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Where will the next coronavirus variant of concern come from? | The Economist - 1 views

  • Mutation is a random process, which is why successful new variants are more likely to come from places where lots of mutation is occurring
  • Airfinity’s hypothesis is that this will occur where few people have had the jab and where many suffer from weakened immune systems.
  • Airfinity’s researchers concluded that Burundi, Tanzania, the Democratic Republic of the Congo, Yemen and Nigeria are most at risk of producing a new variant.
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  • By January 29th, less than 6% of people living in the four African countries had been fully vaccinated against coronavirus. In Burundi, the country the researchers found to be by far the most at risk, that figure was just 0.05%
  • Distribution remains difficult in poor countries: many lack the necessary infrastructure, including reliable electricity, to store vaccines at very low temperatures. Vaccine hesitancy is a problem, too.
  • It does not take into account the differing protection offered by various covid vaccines, natural immunity, the impact of population density on transmission or covid treatment options for immunocompromised people. Estimating the number of immunocompromised people is itself hard: the model the data was based on includes only a few conditions. Others, like severe type-1 diabetes or rheumatoid arthritis, were absent. Nor is everyone with such conditions immunocompromised. But the study still offers insight into where to look for future variants—and where to focus efforts on increasing the supply and take-up of vaccines.
Javier E

Opinion | A Titanic Geopolitical Struggle Is Underway - The New York Times - 0 views

  • There are many ways to explain the two biggest conflicts in the world today, but my own shorthand has been that Ukraine wants to join the West and Israel wants to join the Arab East — and Russia, with Iran’s help, is trying to stop the first, and Iran and Hamas are trying to stop the second.
  • They reflect a titanic geopolitical struggle between two opposing networks of nations and nonstate actors over whose values and interests will dominate our post-post-Cold War world — following the relatively stable Pax Americana/globalization era that was ushered in by the fall of the Berlin Wall in 1989 and the collapse of the Soviet bloc, America’s chief Cold War rival.
  • On one side is the Resistance Network, dedicated to preserving closed, autocratic systems where the past buries the future. On the other side is the Inclusion Network, trying to forge more open, connected, pluralizing systems where the future buries the past.
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  • “What Putin wants is to transform the world order” that evolved since World War II and the post-Cold War — where “the competition between nations was about who can be richer and who can help their people prosper the most . … Putin hates that world because he loses in that world — his system is a loser in a peaceful, global, wealth-enhancing paradigm. And so what he wants is to move us back to dog-eat-dog, to a 19th-century, great power competition, because he thinks he can, if not win, be more effective there. … Let’s not think that this is a Ukrainian problem; this is a problem for us all.”
  • These wars very much are our business — and now clearly inescapable, since we’re deeply entwined in both conflicts. What’s crucial to keep in mind about America — as the leader of the Inclusion Network — is that right now we’re fighting the war in Ukraine on our terms, but we’re fighting the war in the Middle East on Iran’s terms.
  • CNN recently described, per a source familiar with it, a declassified U.S. intelligence assessment provided to Congress saying that Russia had lost 87 percent of its preinvasion active-duty ground troops and two-thirds of its tanks that it had prior to its invasion of Ukraine. Putin can still inflict a lot of damage on Ukraine with missiles, but his dream of occupying the whole country and using it as a launching pad to threaten the Inclusion Network — particularly the NATO-protected European Union — is now out of reach. Thank you, Kyiv.
  • At a breakfast with NATO leaders devoted to the Ukraine issue at Davos this year, Canada’s deputy prime minister, Chrystia Freeland, noted that it is we, the West, who should be thanking the Ukrainians, not forcing them to beg us for more weapons.
  • China under President Xi Jinping straddles the two networks, along with much of what’s come to be called the global south. Their hearts, and often pocketbooks, are with the Resistors but their heads are with the Includers
  • the Resistance Network “is orchestrated by Iran, Islamists and jihadists” in a process they refer to as the “unity of battlefields.” This network, he noted, “seeks to bridge militias, rejectionists, religious sects and sectarian leaders,” creating an anti-Israel, anti-American, anti-Western axis that can simultaneously pressure Israel in Gaza, in the West Bank and on the Lebanon border — as well as America in the Red Sea, in Syria and in Iraq and Saudi Arabia from all directions.
  • In stark contrast, Koteich said, stands the Inclusion Network, one that’s focused on “weaving together” global and regional markets instead of battlefronts, business conferences, news organizations, elites, hedge funds, tech incubators and major trade routes. This inclusion network, he added, “transcends traditional boundaries, creating a web of economic and technological interdependence that has the potential to redefine power structures and create new paradigms of regional stability.”
  • things are different in the Middle East. There, it is Iran that is sitting back comfortably — indirectly at war with Israel and America, and sometimes Saudi Arabia, by fighting through Tehran’s proxies: Hamas in Gaza, the Houthis in Yemen, Hezbollah in Lebanon and Syria, and Shiite militias in Iraq.
  • Iran is reaping all the benefits and paying virtually no cost for the work of its proxies, and the U.S., Israel and their tacit Arab allies have not yet manifested the will or the way to pressure Iran back — without getting into a hot war, which they all want to avoid.
  • The members of the Resistance Network are great at tearing down and breaking stuff, but, unlike the Inclusion Network, they have shown no capacity to build any government or society to which anyone would want to emigrate, let alone emulate
  • For all of these reasons, this is a moment of great peril as well as great opportunity — especially for Israel. The competition between the Resistance Network and the Inclusion Network means that the region has never been more hostile or more hospitable to accepting a Jewish state.
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