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Javier E

Opinion | Want to See My Genes? Get a Warrant - The New York Times - 0 views

  • While there may be broad public support for a technique that solved serial murders, just because technology allows for a new type of investigation doesn’t mean the government should be allowed to use it in all cases.
  • 90 percent of Americans of European descent will be identifiable from their DNA within a year or two, even if they have not used a consumer DNA service
  • As for easy access, GEDmatch’s website provides exactly this opportunity. Consumers can take profiles generated from other commercial genetic testing services, upload them free and compare them to other profiles. So can the police.
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  • If the police felt free to use it in an assault case, why not shoplifting, trespassing or littering?
  • When you consent to genetic sleuthing, you are also exposing your siblings, parents, cousins, relatives you’ve never met and even future generations of your family
  • Legitimate consent to the government’s use of an entire family tree should involve more than just a single person clicking “yes” to a website’s terms and conditions.
  • the police usually confirm leads by collecting discarded DNA samples from a suspect. How comfortable should we be that a school resource officer hung around a high school cafeteria waiting to collect a teenager’s “abandoned” DNA?
  • All of these issues point to one problem: Police use of genetic genealogy is virtually unregulated
  • Our genetic and digital identities raise similar questions of autonomy, civil liberties, and intrusion by public and private entities.
  • Rather than wait for the courts to deal with difficult and novel issues about genetic surveillance and privacy, state legislatures and attorneys general should step in and articulate guidelines on how far their law enforcement agencies should go.
Javier E

Ice Age Europeans had some serious drama going on, according to their genomes - The Was... - 0 views

  • before researchers could start analyzing that genetic material, they had to get it. DNA degrades over time, so extracting it from ancient human remains is difficult and costly.
  • In the end, they had data from 51 individuals — a tenfold increase over the measly four that once gave researchers their only glimpses into this period.
  • "Trying to represent this vast period of European history with just four samples is like trying to summarize a movie with four still images," Reich said. "With 51 samples, everything changes; we can follow the narrative arc; we get a vivid sense of the dynamic changes over time.
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  • One of the oldest genomes studied came from a thigh bone discovered in Goyet Cave in Belgium and given the unwieldy name GoyetQ116-1. Radiocarbon dating pegs the Goyet individual at some 35,000 years old,
  • Around 1,000 years after the Goyet individual was found, a new culture swept through Europe: the Gravettians. Analysis of genetic material from the time shows that art and artifacts weren't the only things changing. The Gravettians' DNA was significantly different from their Aurignacian predecessors, suggesting that they were a completely separate lineage.
  • Goyet guy's descendants retreated to the Iberian Peninsula (modern day Spain and Portugal) and waited for their time to come again.
  • It did, some 15,000 years later. Probably spurred by climate changes as glaciers began to recede, this dormant lineage expanded back into the rest of Europe, bearing a new culture known as Magdalenian.
  • Not long after that, their genomes started to look like those of people from the Middle East and the Caucasus, suggesting that new arrivals from the southeast were mingling with — and in some cases supplanting — the existing population.
  • This was a surprise, because researchers used to think that transition happened much later, when Turkish farmers introduced agriculture to Europe some 8,500 years ago.
  • The genetic analysis allowed researchers to trace the inexorable decline of Neanderthal DNA, which was two to three times more prominent in early human genomes than it is in modern-day ones. This supports theories that early humans interbred with Neanderthals, but that their DNA was toxic to us and gradually weeded out by natural selection over the course of millennia.
Javier E

Cousins of Neanderthals Left DNA in Africa, Scientists Report - NYTimes.com - 0 views

  • t's seems the height of arrogance for any paleoanthropologist to assume that the bones they have in hand represent all knowledge. That what is certainly the vast majority of still-existing bones and materials still hidden in earth doesn't represent anything they they don't already know from the relative scraps they have found.
  • On the other hand, the geneticists don't have "evidence", they have hints or suggestions. Sure, they can see existing genes in a modern DNA sampling that have similarities to genes from an older sampling dug from the earth, but how those genes came to be in the modern specimen is completely assumptive guesswork. The geneticists are looking at two end points and are 1. assuming they are of the same linear history and then 2. are assuming all the points in between. Rather grand assumptions.
  • evolution isn't something you "believe" in it is something you understand.
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  • The real problem is in how information is obtained. Anthropologists study bones and are forced to draw conclusions based on ancient, fragmentary evidence, and geneticists can obtain complete DNA samples, but not of very ancient organisms. Both are forced to make assumptions based on different sources of evidence. With regard to the accepted tree of life (much as a bridge lacking most of the cables or roadway) it's very much a work in progress!
Grace Gannon

Oklahoma cases solved: DNA tests used. - 0 views

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    Developments in the field of DNA research and technology have resulted in an overall greater understanding of the truth of the past. Human remains of six people who died in 2013 were tested for DNA and have effectively been identified. These technological and scientific advancements allow us to have a more complete, truthful understanding of the past.
Javier E

DNA Reveals the Hidden Jewish Ancestry of Latin Americans - The Atlantic - 0 views

  • Chacón-Duque and his colleagues pieced together the genetic record by sampling DNA from 6,500 people across Brazil, Chile, Colombia, Mexico, and Peru, which they compared to that of 2,300 people all over the world. Nearly a quarter of the Latin Americans shared 5 percent or more of their ancestry with people living in North Africa and the eastern Mediterranean, including self-identified Sephardic Jews. DNA alone cannot prove that conversos were the source of this ancestry, but it fits with the historical record.
  • This pattern of widespread but low North African and eastern Mediterranean ancestry in the population suggests that its source is centuries old, putting the date around the early days of New Spain.
  • Geneticists have also noticed rare genetic diseases prevalent in Jews popping up in Latin America. “It’s not just one disease. It’s like, wow, this isn’t a coincidence,
Javier E

A New Clue to the 1545 Cocolitzli Epidemic in Mexico - The Atlantic - 0 views

  • In less than a century, the number of people living in Mexico fell from an estimated 20 million to 2 million. “It’s a massive population loss. Really, it’s impressive,” says Rodolfo Acuña-Soto, an epidemiologist at the National Autonomous University of Mexico. What can even kill so many people so quickly?
  • Now, DNA from 16th-century cocolitzli victims has offered up a somewhat unexpected new candidate: Salmonella enterica, or the bacteria that cause paratyphoid fever. The DNA evidence comes from the teeth of 11 people buried in a large Mixtec cemetery in southern Mexico
  • Bos’s team repurposed a method called metagenomics that sequences all of the DNA in a sample, generating a long list of all bacteria present in the teeth. One researcher went through the list by hand, and a specific strain of Salmonella enterica popped up repeatedly. Dental pulp samples from five people who died before European contact but buried in the same site contained no significant amounts of S. enterica.
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  • The study authors acknowledge that S. enterica may have interacted with other circulating pathogens. The method does not rule them out. In particular, the team can only detect DNA, but some viruses carry RNA instead. “If all these people died from RNA viruses, we will never know, at least not with these techniques,
bluekoenig

What Ancient DNA Says About Puerto Rico's History - The Atlantic - 0 views

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    Native Puerto Ricans are learning that the ancient Taíno people, once thought entirely wiped out, who inhabited the island pre-colonization still live on in their DNA
Javier E

Clovis People Probably Not Alone in North America - NYTimes.com - 0 views

  • “The colonization of the Americas involved multiple technologically divergent, and possibly genetically divergent, founding groups.”
  • Indeed, new genetic evidence described in the current issue of the journal Nature shows that the Americas appeared to be first populated by three waves of migrants from Siberia: one large migration about 15,000 years ago, followed by two lesser migrations. Such a pattern had been hypothesized 25 years ago on the basis of Native American language groups spoken today, but had not been widely accepted by linguistics scholars.
  • human DNA from the cave, extracted from coprolites, or dried feces, pointed to Siberian-East Asian origins of the people.
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  • The findings lend support to an emerging hypothesis that the Clovis technology, named for the town in New Mexico where the first specimens were discovered, actually arose in what is now the Southeastern United States and moved west to the Plains and the Southwest. The Western Stemmed technology began, perhaps earlier, in the West. Most artifacts of that kind have been found on the West Coast and in Idaho, Nevada, Utah and Wyoming. “We seem to have two different traditions coexisting in the United States that did not blend for a period of hundreds of years,” Dr. Jenkins said.
Javier E

Scientists Seek Ban on Method of Editing the Human Genome - NYTimes.com - 0 views

  • A group of leading biologists on Thursday called for a worldwide moratorium on use of a new genome-editing technique that would alter human DNA in a way that can be inherited.
  • The biologists fear that the new technique is so effective and easy to use that some physicians may push ahead before its safety can be assessed. They also want the public to understand the ethical issues surrounding the technique, which could be used to cure genetic diseases, but also to enhance qualities like beauty or intelligence. The latter is a path that many ethicists believe should never be taken.
  • a technique invented in 2012 makes it possible to edit the genome precisely and with much greater ease. The technique has already been used to edit the genomes of mice, rats and monkeys, and few doubt that it would work the same way in people.
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  • The technique holds the power to repair or enhance any human gene. “It raises the most fundamental of issues about how we are going to view our humanity in the future and whether we are going to take the dramatic step of modifying our own germline and in a sense take control of our genetic destiny, which raises enormous peril for humanity,”
  • The paper’s authors, however, are concerned about countries that have less regulation in science. They urge that “scientists should avoid even attempting, in lax jurisdictions, germline genome modification for clinical application in humans” until the full implications “are discussed among scientific and governmental organizations.”
  • Though such a moratorium would not be legally enforceable and might seem unlikely to exert global influence, there is a precedent. In 1975, scientists worldwide were asked to refrain from using a method for manipulating genes, the recombinant DNA technique, until rules had been established.
  • Though highly efficient, the technique occasionally cuts the genome at unintended sites. The issue of how much mistargeting could be tolerated in a clinical setting is one that Dr. Doudna’s group wants to see thoroughly explored before any human genome is edited.
  • “We worry about people making changes without the knowledge of what those changes mean in terms of the overall genome,” Dr. Baltimore said. “I personally think we are just not smart enough — and won’t be for a very long time — to feel comfortable about the consequences of changing heredity, even in a single individual.”
  • Many ethicists have accepted the idea of gene therapy, changes that die with the patient, but draw a clear line at altering the germline, since these will extend to future generations. The British Parliament in February approved the transfer of mitochondria, small DNA-containing organelles, to human eggs whose own mitochondria are defective. But that technique is less far-reaching because no genes are edited.
  • There are two broad schools of thought on modifying the human germline, said R. Alta Charo, a bioethicist at the University of Wisconsin and a member of the Doudna group. One is pragmatic and seeks to balance benefit and risk. The other “sets up inherent limits on how much humankind should alter nature,” she said. Some Christian doctrines oppose the idea of playing God, whereas in Judaism and Islam there is the notion “that humankind is supposed to improve the world.” She described herself as more of a pragmatist, saying, “I would try to regulate such things rather than shut a new technology down at its beginning.
  • The Doudna group calls for public discussion, but is also working to develop some more formal process, such as an international meeting convened by the National Academy of Sciences, to establish guidelines for human use of the genome-editing technique.“We need some principled agreement that we want to enhance humans in this way or we don’t,” Dr. Jaenisch said. “You have to have this discussion because people are gearing up to do this.”
Javier E

In ancient DNA, the story of how Native Americans thrived - and then were wiped out - T... - 0 views

  • Llamas and his colleagues figured out when the initial American settlers left Siberia via the land bridge over what is now the Bering strait. Their answer: roughly 23,000 years ago.
  • From there, it seemed that a group of about 2,000 child-bearing women (suggesting a population of some 10,000 people total) spent the next 6,000 years in genetic isolation — meaning that they weren’t intermarrying with other groups or branching off into separate ones. They just hunkered down together, and lived as their ancestors did.
  • That matches most scientists’s understanding of the early colonization of the Americas. In 20,000 BC, Alaska and pretty much all of Canada would have been encased in a vast ice sheet. Traversing it was impossible — nothing could survive the 3,000 mile trek across a barren glacier, let alone a motley crew of prehistoric humans.
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  • Historically, scientists have believed that early settlers known as the Clovis people migrated south through an ice-free corridor that formed as the glaciers melted at the end of the Ice Age, roughly 11,500 years ago. That “Clovis first” theory, though dominant for most of the 20th century, is a tricky one: recent radiocarbon analysis of human remains discovered at an ancient site in Chile found they were about 14,000 years old. Either the analysis was wrong, or the theory was.
  • A second and increasingly popular possibility is that the people of Beringia, as the land bridge is known, built themselves some boats, traveled south and began settling the American coastline long before the inland ice had melted. The Science Advances study backs up that theory: It found that the genetic diversity of early Americans exploded about 16,000 years ago, suggesting that they’d made it to the warm, wide open spaces of the North and South American continents and flourished.
  • By 14,000 years before present, humans inhabited the Americas from Alaska to Chile.
  • mitochondrial DNA only offers clues about matrilineal lines of kinship — men, and women who didn’t have children, are left out of the equation.
Javier E

| Harvard Magazine - 0 views

  • Who Killed the Men of England? The written record of history meets genomics, evolution, demography, and molecular archaeology.
  • more than a million men vanished without a trace. They left no descendants. Historians know that something dramatic happened in England just as the Roman empire was collapsing. When the Anglo-Saxons first arrived in that northern outpost in the fourth century a.d.--whether as immigrants or invaders is debated--they encountered an existing Romano-Celtic population estimated at between 2 million and 3.7 million people. Latin and Celtic were the dominant languages.
  • Yet the ensuing cultural transformation was so complete, says Goelet professor of medieval history Michael McCormick, that by the eighth century, English civilization considered itself completely Anglo-Saxon, spoke only Anglo-Saxon, and thought that everyone had “come over on the Mayflower, as it were.”
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  • Working along an east-west transect through central England and Wales, the scientists discovered that the mix of Y-chromosomes characteristic of men in the English towns was very different from that of men in the Welsh towns: Wales was the primary Celtic holdout in Western Britannia during the ascendance of the Anglo-Saxons. Using computer analysis, the researchers explored how such a pattern could have arisen and concluded that a massive replacement of the native fourth-century male Britons had taken place. Between 50 percent and 100 percent of indigenous English men today, the researchers estimate, are descended from Anglo-Saxons who arrived on England’s eastern coast 16 centuries ago.
  • So what happened? Mass killing, or “population replacement,” is one possible explanation. Mass migration of Anglo-Saxons, so that they swamped the native gene pool, is another.
  • Yet no archaeological or historical evidence from the fifth and sixth centuries hints at the immense scale of violence or migration that would be necessary to explain this genetic legacy. The science hinted at an untold story.
  • across entire fields of inquiry, the traditional boundaries between history and prehistory have been melting away as the study of the human past based on the written record increasingly incorporates the material record of the natural and physical sciences.
  • The study of the human past, in other words, has entered a new phase in which science has begun to tell stories that were once the sole domain of humanists.
  • Thomas had found that genetically, not one of the English towns he sampled was significantly different from the others. Welsh towns, on the other hand, were significantly different from each other and from the English towns.
  • Most importantly, he found that inhabitants of  the Dutch province of Friesland were indistinguishable genetically from the English town-dwellers. Friesland is one of the known embarkation points of the Angl0-Saxons--and the language spoken there is the closest living relative to English.
  • The implications are profound: “Suddenly, we have all these genuine historical observations that need to be taken on board by historians and archaeologists and they raise a whole series of new questions, focusing particularly on…what is going on at the intimate level of this new civilization that is being born in the ruins of the Roman empire. The history of Europe will never be the same.”
  • But most archaeologists and historians who understand the economic capacity of the era, he noted, “find such massive contributions to the English gene pool to be completely unacceptable.
  • “But still, the genetic data are quite robust,” Thomas pointed out. “This is where the idea of an apartheid-like social structure comes in.” He has advanced a theory that a sexually biased, ethnically driven reproductive pattern, in which Anglo-Saxon males fathered children with Anglo-Saxon females and possibly Celtic females, while the reproductive activities of Romano-Celtic males were more restricted, is the most plausible explanation for the demographic, archaeological, and genetic patterns seen today. 
  • In an attempt to explain the remarkable similarity between Frisian and English towns, Thomas and colleagues constructed a population simulation model on a computer. He tested many theories: common ancestry dating back to the Neolithic age; background migration over centuries and even millennia; and a mass-migration event that, he calculated, would have had to involve at least 50 percent replacement--the movement, in other words, of a million people.
  • Simulating such an advantage, and choosing an arbitrary figure of 10 percent migration, Thomas found that the Y chromosomes of native Britons could have been replaced in the general population in as few as five generations. 
  • by the 1970s, he continues, scholars began to realize there never was a homogenous “nation” of Germans in northern Europe, just small tribes that coalesced along the Roman frontier in what were political and cultural, rather than biological, federations, as their very names suggest: Alemanni, meaning “all men”; Goths, meaning “good guys.”
  • The Romans, scholars believed, provided a common enemy, and that unified the disparate Germanic tribes. This line of reasoning led historians to a further thought: maybe the Anglo-Saxon identity was similarly socially constructed, and not biological after all
  • More recent historical scholarship, therefore, has increasingly emphasized discovering the extent to which the barbarian migrations were really a process of ethnogenesis--the creation of new ethnic identities, as the merchant’s story illustrates.
  • “There is lots of evidence for it,” McCormick says. “But now you have Mark Thomas telling us that you could actually study mating patterns. That is utterly unanticipated.” The work raises a host of new questions: What was women’s role in the barbarian settlements? Were Anglo-Saxon men mating with Celtic women? Or were there women in those invading boats, and if so, how many? What happened to the Romano-Celtic men? Were they killed? 
  • There is some support for this in ancient English laws, which indicate that Britons and Anglo-Saxons were legally and economically different even in the seventh century, long after the initial migration. Thomas cited wergild (blood money) payments as one example: “Killing an Anglo-Saxon was a costly business, but killing a native Briton was quite cheap.” This points to differences in economic status. And differences in wealth “almost always result in differences in reproductive output,” he said. “Sometimes two- and three-fold differences.” To the extent Anglo-Saxons were able to have and support more children, this could lead to a gradual replacement of the indigenous Y-chromosome over many generations
  • The Y-chromosome can be a particularly revealing signature of the past when compared to other kinds of genetic data. Among African Americans in the United States, for example, Y-chromosomes are about 33 percent European, he says, though the proportion varies from city to city. But those same African Americans’ mitochondrial DNA, which comes from the female line, is only about 6 percent European. And that, says Reich, “tells you about the history of this country, in which men contributed about three-fourths of the European ancestry that is present in the African-American population data. The data speak to a history in which white male slaveowners exploited women of African descent--a fact that is well documented in the historical record. That there is evidence of this in genetic data should be no surprise.”
  • Most Americans associate Medellín with the drug cartels of that isolated region. But the remoteness has also preserved a genetic legacy that can be traced to the conquistadores. As described in a paper by Andrés Ruiz-Linares of University College London, the Y-chromosomes of men in Medellín are 95 percent European, while the mitochondrial DNA of the women is 95 percent Native American. Spanish men and Native American women created a new population--confirming the recorded history of the region.
  • The pattern of sexual exploitation by a dominant group seen in the preceding examples is not at all unusual in the human genetic record, says Reich’s frequent collaborator, Nick Patterson, a senior research scientist at the Broad Institute of MIT and Harvard. The Icelandic sagas record that the exiles who settled that island raided Scotland and Ireland, kidnapping Celtic women. And the genes corroborate this account. The mitochondrial DNA of the women is Celtic, the Y-chromosomes are Nordic
  • Fortunately, the science of the human past has progressed in these other areas no less than in the field of genetics. Innovations in archaeological analysis have had a profound impact
  • After the fall of the Roman empire, “you get this layer called ‘dark earth’” in the archaeological stratigraphy, he says. “People thought the empire fell and the cities turned into garden [plots]. That is how dark earth was understood up until about five years ago,
  • “In the Roman excavations,” says McCormick, “there were pots and stone buildings and columns.” But then suddenly you get a layer of nothing but dark, humus-looking soil. What actually happened, Galinié and others have found, is that people shifted to organic building materials. “They had thatched roofs and wooden houses, they didn’t have Roman garbage removal, and they just dumped the ashes and charcoal from their hearths out in the road and all of that compacted. It is extremely rich, extremely dense,
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    Who Killed the Men of England? The written record of history meets genomics, evolution, demography, and molecular archaeology.
knudsenlu

Mapping Human Migrations With Ancient Dental Plaque - The Atlantic - 0 views

  • tartar is very durable. Just ask these Neanderthals, whose 40,000-year-old tartar scientists recently analyzed to figure out the real paleo diet. Tartar grows in layers—almost like tree rings—entombing DNA from tiny bits of food as well as bacteria in the mouth. Forty thousand years later, scientists can analyze that DNA to reconstruct what was going on in the mouths of long-dead Neanderthals.
  • Having traveled so far back in time using ancient tartar, some of the same scientists have embarked on a more ambitious project: using the DNA from the bacteria in tartar to figure out how humans settled the 10 million square miles of Polynesia.
  • Humans first reached the Society Islands, in the center of the Polynesian Triangle, perhaps around 1,000 AD. Then in the span of just a couple hundred years, they took canoes across vast tracts of open ocean to find specks of inhabitable rock as far-flung as Hawaii, New Zealand, and Easter Island. How Polynesians navigated these waters in the 11th century is a subject of considerable fascination. But even more basically, archaeologists are not sure exactly when the islands were settled and in what order. That’s where the tartar comes in.
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  • When Weyrich samples tartar from teeth, she’s careful to pick jaws that have more than one tooth and to always leave some tartar behind. You don’t want to destroy it all, she explains, because you never know what techniques might come along in the future.
Javier E

A Teenager Was Bullied. His Ancestors Saved Him. - The New York Times - 0 views

  • In March 2008, Dennis Richmond Jr. watched “Roots” with his father, and it changed his life. It was a Sunday, the Richmonds’ day for leafing through family photographs in their apartment in Yonkers, N.Y., looking at relatives going back about a century. “Roots,” Alex Haley’s semifictional account of his family’s journey from West Africa, posed a challenge: How far back could young Dennis trace his own ancestors?
  • When he thought about his grandmother having parents, who in turn had parents, he was floored. “It blew my mind,” he said. “The seed was planted. And I’ve been steadfast ever since.”
  • For Dennis, finding his ancestors became a refuge from his school life, where classmates bullied him both physically and verbally for his studiousness and the way he carried himself.
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  • “I knew, wow, I have slaves in my family, and I would like to know who they are,” he said. “It was an amazing pastime for me. It kept my mind off the fact that I knew that Monday morning I would have to go back to school and get bullied again.”
  • Dennis’s great-uncle, John Sherman Merritt, said it had been very difficult to get information from his elders, especially the great-grandmother who had been born before Emancipation and grew up during Reconstruction.
  • Through his searches he came across the work of a fifth cousin, Teresa Vega, a generation older, who was already engaged in a rigorous study of their ancestors from her apartment in Upper Manhattan.
  • His father, Dennis Sr., knew that there were family mysteries to be unraveled, though he had not tried to unlock them himself. Many of his relatives“don’t look like they’re of African descent,” he said. “Just visualizing our family, you can see that there’s a relation to different ethnic groups.”
  • Hangroot was a community once vibrant, but largely lost to history; its Black and Indigenous residents were mostly gone by 1910 — “gentrified out,” said Ms. Vega, by the twofold pressure of white immigrants and the arrival nearby of the Rockefellers. When a relative gave Dennis a photograph from around 1899 showing his great-great-grandfather as a boy in Hangroot, it put a face on an ancestor and a community Dennis knew only from documents.
  • Dennis learned about the great-great-grandfather in the photograph, how he worked himself to death at 31, and about his mother, born in 1871 in Virginia, the daughter of enslaved parents, who wrote poems that were published in newspapers.
  • Against his difficulties in school, his ancestors became role models. “Because grandpa John died of exhaustion, if I’m not dying from working hard, then why wouldn’t I continue to work hard?” Dennis said. “If I know that one of my ancestors couldn’t read and write for a few years because of the circumstances they were born into, but taught themselves how to do it, why wouldn’t I go online and look up a word that I didn’t know? So I’m learning from these stories. I’m not just finding these things out. They’re empowering me.”
  • Further searches revealed relatives of Mohawk descent.
  • Finally, an archivist at the Rye Historical Society found a bill of sale that Dennis realized referred to his sixth great-grandmother, Margaret Lyon, known as Peg, dated July 7, 1790. For the sum of “Fifty Pounds of New York Money,” she became the legal property of Nathan Merritt Jr., after whose family the Merritt Parkway in Connecticut is named.
  • Through DNA testing on numerous branches of the family, Mr. Richmond and his cousin Ms. Vega said they were able to determine that Peg bore at least one child — Mr. Richmond’s fifth great-grandfather, who was born into slavery — with a member of the white Merritt family that enslaved her.
  • Ms. Vega took the genealogy back a generation further. Peg Lyon, she found, was herself fathered by a man from the family that sold her to the Merritts, the Lyons, a comparably prominent family whose name is given to a park in nearby Port Chester, N.Y. Again, DNA testing confirmed her research.
  • She followed a family trail to Christine Varner, a Lyon descendant still living in Connecticut. Ms. Varner, who is white, said she always believed she might have relatives of African descent. Then Ms. Vega called.
  • In her childhood, her mother had taken her to the old African-American and Native American cemetery to place flowers on the graves. Now she understood why.
  • In the meantime, he said, his genealogy had given him a view of Black history far different from the one he’d learned in school — one that included Northern families like the Lyons and Merritts, Black and white, living in the same community for generations. During the pandemic, he wrote and self-published a book that included his adventures in genealogy, “He Spoke at My School.”
  • “To know that I have Indigenous DNA, on my dad’s side, just makes for a true American story,” he said. “You had slave owners who had slaves, and who had children with the people that they enslaved. You have people who came to this country from Europe and who had children with Indigenous people. And Indigenous people who had children with stolen Africans.
  • “And then you speed up hundreds of years,” he said, “and you have Dennis.”
Javier E

Opinion | We Need a New Language for Talking About Race - The New York Times - 0 views

  • The other day, while teaching a lecture class, one of us mentioned in passing that the average African American, according to a 2014 paper, is about 24 percent European and less than 1 percent Native American. A student responded that these percentages were impossible to measure, since “race is a social construction.”
  • the fact that race is a social invention and not a biological reality cannot be repeated too much.
  • However, while race is socially constructed, genetic mutations — biological records of ancestry — are not, and the distinction is a crucial one.
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  • To varying degrees, we have all inherited a muddled understanding of race, ancestry and phenotype from the Enlightenment,
  • if we don’t disentangle these concepts, we may miss the great promise of using genetics to push back against a very long and sad history of the misuse of science for pernicious purposes.
  • One of the key moments in the evolution of modern concepts of race occurred in France in 1741, when the members of Bordeaux’s Royal Academy of Sciences held a continentwide essay contest on the “cause” of dark skin and textured hair among African populations. Why, they asked, were Black people Black?
  • this contest signaled a new era of “scientific racism.” In the decades that followed, naturalists increasingly subdivided the human species into several so-called races by things like skin color, hair texture, skull shape and, most perniciously, according to supposedly transcendent essences.
  • genetics — or, for that matter, any science — has the potential to be misused, co-opted by racist ideologies and employed to bolster harmful narratives about racial purity or biological superiority.
  • There is no category for white in genetic analysis; half of his ancestry traces back to regions in Europe. We should never forget that whiteness, like Blackness, is just another social fiction.
  • If, throughout the 18th, 19th and 20th centuries, science put an enormous amount of effort into dividing the human species into separate categories, 21st-century genetic analysis promises to reveal just how meaningless those categories are — and how connected we’ve been all along.
  • it feels urgent that we develop new language for discussing the relationship between identity, ancestry, history and science
  • DNA analysis could help create that language by offering more nuanced ways of looking at individual origins and a more unifying narrative about our shared heritage
  • While, biologically speaking, the idea of individual human races with different origins is as farcical as the medieval belief that elves cause hiccups, the social reality of race is undeniable.
  • The multitude of population clusters, regions and genetic groups reflected in DNA tests counters existing narratives that try to reduce the astonishing variety of the human community to the four or five socially constructed races of man
  • But if we can, at the very least, embrace the understanding that race (a toxic social construction) and ancestry (a shared genetic history) are not only distinct but also fundamentally opposed — and teach that in our classrooms — it could go a long way toward freeing us from some of the binds in which scientific racism have trapped us.
  • The stories embedded in our genes beg to be told. They tell of ancestral diversity that stretches back thousands of years and ultimately underscores all that we — despite superficial physical differences — have in common.
Javier E

Ancient DNA Paints a New Picture of the Viking Age - WSJ - 0 views

  • “It is clear from archaeological artifacts and historical documents that they also took captives,” he said, adding that the new study suggests the number of slaves brought back to Scandinavia by the Vikings was enough to influence genetic composition of the region.The study revealed, too, that primarily females were moved into Scandinavia from the east during this time—which “suggests that the Vikings may have preferentially targeted women and girls as slaves,” Dr. Collard said.
  • The researchers found that, following the Viking Age, there was a notable decline in Baltic and British-Irish ancestries among Scandinavians. While there remains some genetic influence from these regions today, it is “not as much as we would expect,” Dr. Götherström said.
  • “The only credible way I can explain that is a lot of these people that came into Scandinavia during the Viking period didn’t build families and weren’t as efficient in getting children as the people who were already living there,”
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  • The study’s conclusions need to be tempered by the idea that these 300 ancient genomes may not be wholly representative of the region’s overall population
  • Many of the genomes used in the new analysis were collected from individuals uncovered in burial grounds, grave fields and churchyards. But some samples came from people who died in unusual circumstances—including sailors from a Swedish warship that sank off the country’s southeastern coast in 1676, and inhabitants of a settlement known as Sandby borg who were likely massacred during an organized attack in the fifth century.
  • “There is a question of how much you can call it population genomics as opposed to kind of lots of little vignettes,
Javier E

All the Infrastructure a Tyrant Would Need, Courtesy of Bush and Obama - Conor Frieders... - 0 views

  • Bush and Obama have built infrastructure any devil would lust after. Behold the items on an aspiring tyrant's checklist that they've provided their successors:A precedent that allows the president to kill citizens in secret without prior judicial or legislative reviewThe power to detain prisoners indefinitely without charges or trialOngoing warrantless surveillance on millions of Americans accused of no wrongdoing, converted into a permanent database so that data of innocents spied upon in 2007 can be accessed in 2027Using ethnic profiling to choose the targets of secret spying, as the NYPD did with John Brennan's blessingNormalizing situations in which the law itself is secret -- and whatever mischief is hiding in those secret interpretationsThe permissibility of droning to death people whose identities are not even known to those doing the killingThe ability to collect DNA swabs of people who have been arrested even if they haven't been convicted of anythingA torture program that could be restarted with an executive order
  • we're allowing ourselves to become a nation of men, not laws. Illegal spying? Torture? Violating the War Powers Resolution and the convention that mandates investigating past torture? No matter. Just intone that your priority is keeping America safe.
  • This isn't a argument about how tyranny is inevitable. It is an attempt to grab America by the shoulders, give it a good shake, and say: Yes, it could happen here, with enough historical amnesia, carelessness, and bad luck. We're not special. Our voters won't always pick good men and women to represent us.
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  • Stop acting like the president takes an oath to keep us safe, when his job is to protect and defend the Constitution. Doing so keeps the American project safe.
  • Past generations fought monarchies, slaveholders, and Nazis to win, expand, and protect that project. And we're so risk-averse -- not that we're actually minimizing risk -- that we're "balancing" the very rights in our Constitution against a threat with an infinitesimal chance of killing any one of us
  • the national-security state, loosed of the Constitution's safeguards, is a far bigger threat to liberty than al-Qaeda will ever be. Vesting it with more power every year -- expanding its size, power, and functions in secret without any debate about the wisdom of the particulars -- is an invitation to horrific abuses, and it renders the concept of government by the people a joke.
Javier E

Genetics Reveal Europe Is One Big Family - NYTimes.com - 0 views

  • From Ireland to Turkey, Europeans are all related, sharing a link with ancestors who were alive just 1,000 years ago, according to a new genetic study.
  • Peter Ralph and Graham Coop of the University of California used genomic data for 2,257 Europeans to conduct the first such study of an entire continent.
  • A separate study, based on DNA recovered from ancient skeletons, revealed last month that the genetic makeup of modern Europe was established by a wave of newcomers to the continent 6,500 years ago, more recently than previously thought.
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  • other research suggests everyone alive in the world today shares a common ancestor from sometime in the past 3,500 years.
  • scientists had been arguing for 50 years that all humans were too closely related to be divided into races. “The few externally visible differences like skin color or nose shape are not enough to justify divisions,” he said.
  • As recently as the 1950s, British schoolchildren were still studying pre-World War II textbooks that divided Europeans into Germanic, Alpine and Latin “types” according to the shape of their noses.
  • Modern Italians and Spaniards have relatively few common ancestors compared with other European populations, which may be explained by their geography and history.
  • “There have been many studies that we’ve been involved in showing that groups which are fighting each other furiously all the time are actually extremely closely genetically related,” Mark A. Jobling, a geneticist at England’s Leicester University, told Associated Press. “So for example Jewish and non-Jewish populations in the Middle East are extremely similar genetically, but to tell them they are genetic close relatives isn’t going to change their ways.”
Javier E

Bones Under Parking Lot Belonged to Richard III - NYTimes.com - 1 views

  • researchers showed photographs of the skeleton as they found it, stuffed into a grave without a coffin, clearly displaying curvature of the spine as chronicled in contemporary accounts of Richard III’s appearance.
  • DNA samples from the remains had been compared with the DNA of two descendants of the monarch’s family. One of them, Michael Ibsen, is the son of a 16th-generation niece of King Richard’s. The second descendant wished to remain anonymous, the researchers said. The researchers said that the body displayed 10 wounds, 8 of them in the skull and some likely to have caused death, possibly by a blow from a halberd, a kind medieval weapon with an ex-like head on a long pole. Other wounds seem to have been inflicted after his death to humiliate the monarch after his armor was stripped and he was paraded naked over the back of a horse, the researchers said.
Javier E

A man's discovery of bones under his pub could forever change what we know about the Ir... - 0 views

  • “Celtic” languages were not imports to the region but instead were developed somewhere in the British Isles or the Iberian Peninsula — and then spread eastward into continental Europe.
  • His doubts about the traditional view arose as he was studying inscriptions on artifacts from southern Portugal. The inscriptions on those artifacts strongly resembled the languages known as Celtic, yet they dated as far back as 700 B.C. This placed Celtic languages far from the Celt homelands in the middle of Europe at a very, very early date.
  • “What it shows is that the language that became Irish was already out there — before 700 B.C. and before the Iron Age,” Koch said. “It just didn’t fit with the traditional theory of Celtic spreading west to Britain and Iberia.”
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  • Numerous digs, most notably in Austria and Switzerland, have traced the outlines of the Celts. The artifacts offer evidence going back as far as about 800 B.C. The ancient Greeks and Romans also left written accounts of the Celts, and probably knew them well — the Celts sacked Rome around 390 B.C. and attacked Delphi in Greece in 279 B.C.
  • It seemed plausible that this group that had invaded Rome had invaded Ireland as well, and in the standard view, it was this people that eventually made it to Ireland.
  • For decades, however, archaeologists and other scholars have noted just how flimsy the evidence is for that standard account and how broad, nonetheless, is the application of the word.
  • n recent years, some archaeologists have proposed that the traditional story of the Celts' invasion was, in a sense, exactly wrong — the culture was not imported but exported — originating on the western edge of Europe much earlier than previously thought and spreading into the continent.
  • it flowed from the western edge of Europe, what he calls “the Atlantic zone” — into the rest of the continent. In many places of the Atlantic zone, he notes, people were buried in passages aligned with the solstices, a sign that they shared a unified belief system.
  • “From about 5,000 B.C. onwards, complicated ideas of status, art, cosmology were being disseminated along the Atlantic seaways,” Cunliffe said, and that culture then spread eastward.
  • “If we’re right, the roots of what is known as ‘Celtic’ culture go way way back in time,” Cunliffe said. “And the genetic evidence is going to be an absolute game-changer.”
  • If the new scholarship proves correct, exactly what to do with the word Celtic will probably be a matter of some dispute: Should it be applied to languages or cultures that, no matter how clearly defined, were largely uninfluenced by the historical Celts of continental Europe?
  • Complicating any answer are old ethnic antagonisms: The old notions of a distinct “Celtic race” or “Irish race” have been used not just for poetic tributes, but for scorn.
  • According to the genetic research, the Irish are at the extreme end of a genetic wave that washed across Europe, a wave of migrants that swept westward from above the Black Sea across Europe about 2,500 B.C.
  • The way to think about genetic variation in Europe is that it is more of a gradient than it is of sharp boundaries," said Bradley, the DNA researcher. "Sometimes, cultural features like language and natural borders can coincide with genetics, but most times not. Genetics is fuzzy, and it doesn't follow political and cultural borders."
  • "The public will always want a place on the map and for someone to point and say, 'This where the Irish are from,'
  • "But there’s going to be no way to do that. These groups were frequently traveling east-west across Europe, from one place to another. Everyone is a mix.”
Javier E

Who Arrived in the Americas First? - NYTimes.com - 0 views

  • The first evidence to raise significant questions about the Clovis model emerged in the late 1970s, when the anthropologist Tom Dillehay came across a prehistoric campsite in southern Chile called Monte Verde. Radiocarbon dating of the site suggested that the first campfires were lighted there, all the way at the southern tip of South America, well before the first Clovis tools were made
  • Professor Waters announced finding dozens of stone tools along a Texas creekbed. After using a technique that measures the last time the dirt around the stones was exposed to light, Professor Waters concluded, in a paper in Science, that the site was at least 15,000 years old — which would make it the earliest reliably dated site in the Americas.
  • Having compared the DNA of modern American Indians with that of groups living in Asia today, scholars have estimated that the last common ancestor of the two peoples probably lived between 16,000 and 20,000 years ago. That figure doesn’t square with the arrival of the Clovis people from Asia only 13,500 years ago.
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  • We now know people were in the Americas earlier than 14,000 years ago. But how much earlier, and how did they get to a continent sealed off by thick sheets of ice?
  • Working theories vary. Some scholars hypothesize that people migrated from Asia down the west coast of North America in boats. Others suggest variations on the overland route. One theory even argues that some early Americans might have come by boat from Europe via the North Atlantic, despite the fact that the DNA of modern American Indians does not suggest European origins. After 80 years under Clovis’s spell, scholars are once again venturing into unknown territory — and no one is ready to rule anything out yet.
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