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States and experts begin pursuing a coronavirus national strategy in absence of White H... - 0 views

  • A national plan to fight the coronavirus pandemic in the United States and return Americans to jobs and classrooms is emerging — but not from the White House.
  • a collection of governors, former government officials, disease specialists and nonprofits are pursuing a strategy that relies on the three pillars of disease control:
  • Ramp up testing to identify people who are infected.
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  • Find everyone they interact with by deploying contact tracing on a scale America has never attempted before.
  • focus restrictions more narrowly on the infected and their contacts so the rest of society doesn’t have to stay in permanent lockdown.
  • Instead, the president and his top advisers have fixated almost exclusively on plans to reopen the U.S. economy by the end of the month, though they haven’t detailed how they will do so without triggering another outbreak
  • Administration officials, speaking on the condition of anonymity to describe internal deliberations, say the White House has made a deliberate political calculation that it will better serve Trump’s interest to put the onus on governors — rather than the federal government — to figure out how to move ahead.
  • without substantial federal funding, states’ efforts will only go so far
  • The next failure is already on its way, Frieden said, because “we’re not doing the things we need to be doing in April.”
  • In recent days, dozens of leading voices have coalesced around the test-trace-quarantine framework, including former FDA commissioners for the Trump and George W. Bush administrations, Microsoft founder Bill Gates and top experts at Johns Hopkins, Columbia and Harvard universities.
  • On Wednesday, former president Barack Obama weighed in, tweeting, “Social distancing bends the curve and relieves some pressure … But in order to shift off current policies, the key will be a robust system of testing and monitoring — something we have yet to put in place nationwide.”
  • And Friday, Apple and Google unveiled a joint effort on new tools that would use smartphones to aid in contact tracing.
  • What remains unclear is whether this emerging plan can succeed without the backing of the federal government.
  • “It’s mind-boggling, actually, the degree of disorganization,” said Tom Frieden, former Centers for Disease Control and Prevention director. The federal government has already squandered February and March, he noted, committing “epic failures” on testing kits, ventilator supply, protective equipment for health workers and contradictory public health communication.
  • Experts and leaders in some states say remedying that weakness should be a priority and health departments should be rapidly shored up so that they are ready to act in coming weeks as infections nationwide begin to decrease
  • In America, testing — while still woefully behind — is ramping up. And households across the country have learned over the past month how to quarantine. But when it comes to the second pillar of the plan — the labor-intensive work of contact tracing — local health departments lack the necessary staff, money and training.
  • In South Korea, Taiwan, China and Singapore, variations on this basic strategy were implemented by their national governments, allowing them to keep the virus in check even as they reopened parts of their economy and society
  • In a report released Friday, the Johns Hopkins Center for Health Security and the Association of State and Territorial Health Officials — which represents state health departments — estimate 100,000 additional contact tracers are needed and call for $3.6 billion in emergency funding from Congress.
  • “We can’t afford to have multiple community outbreaks that can spiral up into sustained community transmission,” he said in the interview.
  • Unless states can aggressively trace and isolate the virus, experts say, there will be new outbreaks and another round of disruptive stay-at-home orders.
  • “All people are talking about right now is hospital beds, ventilators, testing, testing, testing. Yes, those are important, but they are all reactive. You are dealing with the symptoms and not the virus itself,”
  • The nonprofit Partners in Health quickly put together a plan to hire and train 1,000 contact tracers. Working from their homes making 20 to 30 calls a day, they could cover up to 20,000 contacts a day.
  • Testing on its own is useless, Nyenswah explained, because it only tells you who already has the virus. Similarly, tracing alone is useless if you don’t place those you find into quarantine. But when all three are implemented, the chain of transmission can be shattered.
  • Until a vaccine or treatment is developed, such nonpharmaceutical interventions are the only tools countries can rely on — besides locking down their cities.
  • to expand that in a country as large as the United States will require a massive dose of money, leadership and political will.
  • “You cannot have leaders contradicting each other every day. You cannot have states waiting on the federal government to act, and government telling the states to figure it out on their own,” he said. “You need a plan.”
  • When Vermont’s first coronavirus case was detected last month, it took two state health workers a day to track down 13 people who came into contact with that single patient. They put them under quarantine and started monitoring for symptoms. No one else became sick.
  • He did the math: If each of those 30 patients had contact with even three people, that meant 90 people his crew would have to locate and get into quarantine. In other words, impossible.
  • Since 2008, city and county health agencies have lost almost a quarter of their overall workforce. Decades of budget cuts have left the them unable to mount such a response. State health departments have recently had to lay off thousands more — an unintended consequence of federal officials delaying tax filings until July without warning states.
  • In Wuhan, a city of 11 million, the Chinese had 9,000 health workers doing contact tracing, said Frieden, the former CDC director. He estimates authorities would need roughly one contact tracer for every four cases in the United States.
  • “In the second wave, we have to have testing, a resource base, and a contact-tracing base that is so much more scaled up than right now,” he said. “It’s an enormous challenge.”
  • Gov. Charlie Baker (R) partnered with an international nonprofit group based in Boston
  • “You will never beat a virus like this one unless you get ahead of it. America must not just flatten the curve but get ahead of the curve.”
  • The group is paying new hires roughly the same salary as census takers, more than $20 an hour. As of Tuesday — just four days after the initial announcement — the group had received 7,000 applicants and hired 150.
  • “There’s a huge untapped resource of people in America if we would just ask.”
  • “There needs to be a crash course in contact tracing because a lot of the health departments where this is going to need to happen are already kind of flat-out just trying to respond to the crisis at hand,”
  • Experts have proposed transforming the Peace Corps — which suspended global operations last month and recalled 7,000 volunteers to America — into a national response corps that could perform many tasks, including contact tracing.
  • On Wednesday, the editor in chief of JAMA, a leading medical journal, proposed suspending the first year of training for America’s 20,000 incoming medical students and deploying them as a medical corps to support the “test, trace, track, and quarantine strategy.”
  • The national organization for local STD programs says $200 million could add roughly 1,850 specialists, more than doubling that current workforce.
  • Technology could also turn out to be pivotal. But the invasive nature of cellphone tracking and apps raises concerns about civil liberties.
  • Such technology could take over some of what contact tracers do in interviews: build a contact history for each confirmed patient and find those possibly exposed. Doing that digitally could speed up the process — critical in containing an outbreak — and less laborious.
  • In China, authorities combined the nation’s vast surveillance apparatus with apps and cellphone data to track people’s movements. If someone they came across is later confirmed as infected, an app alerts them to stay at home.
  • In the United States, about 20 technology companies are trying to create a contact tracing app using geolocation data or Bluetooth pings on cellphones
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The Coronavirus in America: The Year Ahead - The New York Times - 0 views

  • More than 20 experts in public health, medicine, epidemiology and history shared their thoughts on the future during in-depth interviews. When can we emerge from our homes? How long, realistically, before we have a treatment or vaccine? How will we keep the virus at bay
  • The path forward depends on factors that are certainly difficult but doable, they said: a carefully staggered approach to reopening, widespread testing and surveillance, a treatment that works, adequate resources for health care providers — and eventually an effective vaccine.
  • The scenario that Mr. Trump has been unrolling at his daily press briefings — that the lockdowns will end soon, that a protective pill is almost at hand, that football stadiums and restaurants will soon be full — is a fantasy, most experts said.
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  • They worried that a vaccine would initially elude scientists, that weary citizens would abandon restrictions despite the risks, that the virus would be with us from now on.
  • Most experts believed that once the crisis was over, the nation and its economy would revive quickly. But there would be no escaping a period of intense pain.
  • Exactly how the pandemic will end depends in part on medical advances still to come. It will also depend on how individual Americans behave in the interim. If we scrupulously protect ourselves and our loved ones, more of us will live. If we underestimate the virus, it will find us.
  • More Americans may die than the White House admits.
  • The epidemiological model often cited by the White House, which was produced by the University of Washington’s Institute for Health Metrics and Evaluation, originally predicted 100,000 to 240,000 deaths by midsummer. Now that figure is 60,000.
  • The institute’s projection runs through Aug. 4, describing only the first wave of this epidemic. Without a vaccine, the virus is expected to circulate for years, and the death tally will rise over time.
  • Fatality rates depend heavily on how overwhelmed hospitals get and what percentage of cases are tested. China’s estimated death rate was 17 percent in the first week of January, when Wuhan was in chaos, according to a Center for Evidence-Based Medicine report, but only 0.7 percent by late February.
  • Various experts consulted by the Centers for Disease Control and Prevention in March predicted that the virus eventually could reach 48 percent to 65 percent of all Americans, with a fatality rate just under 1 percent, and would kill up to 1.7 million of them if nothing were done to stop the spread.
  • A model by researchers at Imperial College London cited by the president on March 30 predicted 2.2 million deaths in the United States by September under the same circumstances.
  • China has officially reported about 83,000 cases and 4,632 deaths, which is a fatality rate of over 5 percent. The Trump administration has questioned the figures but has not produced more accurate ones.
  • The tighter the restrictions, experts say, the fewer the deaths and the longer the periods between lockdowns. Most models assume states will eventually do widespread temperature checks, rapid testing and contact tracing, as is routine in Asia.
  • In this country, hospitals in several cities, including New York, came to the brink of chaos.
  • Only when tens of thousands of antibody tests are done will we know how many silent carriers there may be in the United States. The C.D.C. has suggested it might be 25 percent of those who test positive. Researchers in Iceland said it might be double that.
  • China is also revising its own estimates. In February, a major study concluded that only 1 percent of cases in Wuhan were asymptomatic. New research says perhaps 60 percent were.
  • The virus may also be mutating to cause fewer symptoms. In the movies, viruses become more deadly. In reality, they usually become less so, because asymptomatic strains reach more hosts. Even the 1918 Spanish flu virus eventually faded into the seasonal H1N1 flu.
  • The lockdowns will end, but haltingly.
  • it is likely a safe bet that at least 300 million of us are still vulnerable.
  • Until a vaccine or another protective measure emerges, there is no scenario, epidemiologists agreed, in which it is safe for that many people to suddenly come out of hiding. If Americans pour back out in force, all will appear quiet for perhaps three weeks.
  • The gains to date were achieved only by shutting down the country, a situation that cannot continue indefinitely. The White House’s “phased” plan for reopening will surely raise the death toll no matter how carefully it is executed.
  • Every epidemiological model envisions something like the dance
  • On the models, the curves of rising and falling deaths resemble a row of shark teeth.
  • Surges are inevitable, the models predict, even when stadiums, churches, theaters, bars and restaurants remain closed, all travelers from abroad are quarantined for 14 days, and domestic travel is tightly restricted to prevent high-intensity areas from reinfecting low-intensity ones.
  • In his wildly popular March 19 article in Medium, “Coronavirus: The Hammer and the Dance,” Tomas Pueyo correctly predicted the national lockdown, which he called the hammer, and said it would lead to a new phase, which he called the dance, in which essential parts of the economy could reopen, including some schools and some factories with skeleton crews.
  • Even the “Opening Up America Again” guidelines Mr. Trump issued on Thursday have three levels of social distancing, and recommend that vulnerable Americans stay hidden. The plan endorses testing, isolation and contact tracing — but does not specify how these measures will be paid for, or how long it will take to put them in place.
  • On Friday, none of that stopped the president from contradicting his own message by sending out tweets encouraging protesters in Michigan, Minnesota and Virginia to fight their states’ shutdowns.
  • China did not allow Wuhan, Nanjing or other cities to reopen until intensive surveillance found zero new cases for 14 straight days, the virus’s incubation period.
  • Compared with China or Italy, the United States is still a playground.Americans can take domestic flights, drive where they want, and roam streets and parks. Despite restrictions, everyone seems to know someone discreetly arranging play dates for children, holding backyard barbecues or meeting people on dating apps.
  • Even with rigorous measures, Asian countries have had trouble keeping the virus under control
  • But if too many people get infected at once, new lockdowns will become inevitable. To avoid that, widespread testing will be imperative.
  • Reopening requires declining cases for 14 days, the tracing of 90 percent of contacts, an end to health care worker infections, recuperation places for mild cases and many other hard-to-reach goals.
  • Immunity will become a societal advantage.
  • Imagine an America divided into two classes: those who have recovered from infection with the coronavirus and presumably have some immunity to it; and those who are still vulnerable.
  • “It will be a frightening schism,” Dr. David Nabarro, a World Health Organization special envoy on Covid-19, predicted. “Those with antibodies will be able to travel and work, and the rest will be discriminated against.”
  • Soon the government will have to invent a way to certify who is truly immune. A test for IgG antibodies, which are produced once immunity is established, would make sense
  • Dr. Fauci has said the White House was discussing certificates like those proposed in Germany. China uses cellphone QR codes linked to the owner’s personal details so others cannot borrow them.
  • As Americans stuck in lockdown see their immune neighbors resuming their lives and perhaps even taking the jobs they lost, it is not hard to imagine the enormous temptation to join them through self-infection
  • My daughter, who is a Harvard economist, keeps telling me her age group needs to have Covid-19 parties to develop immunity and keep the economy going,”
  • It would be a gamble for American youth, too. The obese and immunocompromised are clearly at risk, but even slim, healthy young Americans have died of Covid-19.
  • The virus can be kept in check, but only with expanded resources.
  • Resolve to Save Lives, a public health advocacy group run by Dr. Thomas R. Frieden, the former director of the C.D.C., has published detailed and strict criteria for when the economy can reopen and when it must be closed.
  • once a national baseline of hundreds of thousands of daily tests is established across the nation, any viral spread can be spotted when the percentage of positive results rises.
  • To keep the virus in check, several experts insisted, the country also must start isolating all the ill — including mild cases.
  • “If I was forced to select only one intervention, it would be the rapid isolation of all cases,”
  • In China, anyone testing positive, no matter how mild their symptoms, was required to immediately enter an infirmary-style hospital — often set up in a gymnasium or community center outfitted with oxygen tanks and CT scanners.
  • There, they recuperated under the eyes of nurses. That reduced the risk to families, and being with other victims relieved some patients’ fears.
  • Still, experts were divided on the idea of such wards
  • Ultimately, suppressing a virus requires testing all the contacts of every known case. But the United States is far short of that goal.
  • In China’s Sichuan Province, for example, each known case had an average of 45 contacts.
  • The C.D.C. has about 600 contact tracers and, until recently, state and local health departments employed about 1,600, mostly for tracing syphilis and tuberculosis cases.
  • China hired and trained 9,000 in Wuhan alone. Dr. Frieden recently estimated that the United States will need at least 300,000.
  • There will not be a vaccine soon.
  • any effort to make a vaccine will take at least a year to 18 months.
  • the record is four years, for the mumps vaccine.
  • for unclear reasons, some previous vaccine candidates against coronaviruses like SARS have triggered “antibody-dependent enhancement,” which makes recipients more susceptible to infection, rather than less. In the past, vaccines against H.I.V. and dengue have unexpectedly done the same.
  • A new vaccine is usually first tested in fewer than 100 young, healthy volunteers. If it appears safe and produces antibodies, thousands more volunteers — in this case, probably front-line workers at the highest risk — will get either it or a placebo in what is called a Phase 3 trial.
  • It is possible to speed up that process with “challenge trials.” Scientists vaccinate small numbers of volunteers, wait until they develop antibodies, and then “challenge” them with a deliberate infection to see if the vaccine protects them.
  • Normally, it is ethically unthinkable to challenge subjects with a disease with no cure, such as Covid-19.
  • “Fewer get harmed if you do a challenge trial in a few people than if you do a Phase 3 trial in thousands,” said Dr. Lipsitch, who recently published a paper advocating challenge trials in the Journal of Infectious Diseases. Almost immediately, he said, he heard from volunteers.
  • The hidden danger of challenge trials, vaccinologists explained, is that they recruit too few volunteers to show whether a vaccine creates enhancement, since it may be a rare but dangerous problem.
  • if a vaccine is invented, the United States could need 300 million doses — or 600 million if two shots are required. And just as many syringes.
  • “People have to start thinking big,” Dr. Douglas said. “With that volume, you’ve got to start cranking it out pretty soon.”
  • Treatments are likely to arrive first.
  • The modern alternative is monoclonal antibodies. These treatment regimens, which recently came very close to conquering the Ebola epidemic in eastern Congo, are the most likely short-term game changer, experts said.
  • as with vaccines, growing and purifying monoclonal antibodies takes time. In theory, with enough production, they could be used not just to save lives but to protect front-line workers.
  • Having a daily preventive pill would be an even better solution, because pills can be synthesized in factories far faster than vaccines or antibodies can be grown and purified.
  • Goodbye, ‘America First.’
  • A public health crisis of this magnitude requires international cooperation on a scale not seen in decades. Yet Mr. Trump is moving to defund the W.H.O., the only organization capable of coordinating such a response.
  • And he spent most of this year antagonizing China, which now has the world’s most powerful functioning economy and may become the dominant supplier of drugs and vaccines. China has used the pandemic to extend its global influence, and says it has sent medical gear and equipment to nearly 120 countries.
  • This is not a world in which “America First” is a viable strategy, several experts noted.
  • “If President Trump cares about stepping up the public health efforts here, he should look for avenues to collaborate with China and stop the insults,”
  • If we alienate the Chinese with our rhetoric, I think it will come back to bite us,” he said.“What if they come up with the first vaccine? They have a choice about who they sell it to. Are we top of the list? Why would we be?”
  • Once the pandemic has passed, the national recovery may be swift. The economy rebounded after both world wars, Dr. Mulder noted.
  • In one of the most provocative analyses in his follow-up article, “Coronavirus: Out of Many, One,” Mr. Pueyo analyzed Medicare and census data on age and obesity in states that recently resisted shutdowns and counties that voted Republican in 2016.
  • He calculated that those voters could be 30 percent more likely to die of the virus.
  • In the periods after both wars, Dr. Mulder noted, society and incomes became more equal. Funds created for veterans’ and widows’ pensions led to social safety nets, measures like the G.I. Bill and V.A. home loans were adopted, unions grew stronger, and tax benefits for the wealthy withered.
  • If a vaccine saves lives, many Americans may become less suspicious of conventional medicine and more accepting of science in general — including climate change
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How local officials scrambled to protect themselves against the coronavirus - The Washi... - 0 views

  • Across the country, state and local officials, frustrated by what they described as a lack of leadership in the White House and an absence of consistent guidance from federal agencies, took steps on their own to prepare for the pandemic and protect their communities. In some cases, these actions preceded federal directives by days or even weeks as local officials sifted through news reports and other sources of information to educate themselves about the risks posed by the coronavirus.
  • With scant information about the virus and no warnings against large gatherings, cities such as New Orleans moved ahead in February with massive celebrations that may have turned them into hotspots for the virus.
  • “The leader in global pandemics and protecting the United States starts at the federal level,” said Nick Crossley, the director of emergency management in Hamilton County, Ohio, and past president of the U.S. Council of International Association of Emergency Managers.
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  • He praised Republican Gov. Mike DeWine for taking bold steps early, including declaring a state of emergency when there were only three reported cases on March 9, four days before the federal government followed suit. Thirty states had declared a state of emergency by the time Trump declared a national emergency on March 13.
  • “They didn’t move fast enough,” said Crossley, of the federal government. “And what you’ve seen is more local and state officials sounding the alarm. “We needed a national response to this event.”
  • With seven reported infections in the United States by the end of the day, Health and Human Services Secretary Alex Azar declared a public health emergency on Jan. 31, and Trump announced strict travel restrictions, barring most foreign visitors coming from China. He also imposed the nation’s first mandatory quarantine in 50 years.
  • Officials spent three hours war-gaming how they would respond. The drill prompted the state to send 300 employees home early to test their remote work capability. That unmasked a serious problem: A quarter of the team could not perform their jobs at home because they needed access to secure computer systems.
  • Then he heard the news: The United States had identified its first case of person-to-person transmission involving someone who had not traveled overseas. Also, the World Health Organization classified the coronavirus as a public health emergency of international concern.
  • Chicago Jan. 31: 9,927 cases worldwide, seven cases in the United States
  • Tallahassee Jan. 30: 8,234 cases worldwide, five cases in the United States
  • “We are concerned about our public health system’s capacity to implement these measures, recognizing they may inadvertently distract us from our ongoing tried-and-true efforts to isolate confirmed cases and closely monitor their contacts,” according to a previously unreported Feb. 6 letter. “We also worry about the potential to again overwhelm laboratory capacity, recognizing that national capacity has not been adequate to quickly test our highest-risk individuals.”
  • “In the first few sets of conversations, we were not hearing answers to those questions,” Lightfoot, a Democrat, said of her talks with federal officials. “It was kind of like, either silence, or ‘Do the best you can,’ which was obviously not acceptable.”
  • she drafted a letter to Trump on behalf of the mayors from Detroit, Los Angeles, New York, San Francisco and Seattle. They insisted on clear, written directions from the federal government, according to the letter, and worried about diverting health-care resources during flu season, when hospitals were already stretched.
  • Americans who had visited China’s Hubei province would be forced to quarantine for 14 days, and those who visited other parts of China would be screened for symptoms and asked to isolate themselves for two weeks. Chicago Mayor Lori Lightfoot was caught off guard. The directive came with little guidance. Where were local governments supposed to quarantine the travelers? What would they do if someone refused to quarantine? Who was going to pay for the resources needed to quarantine people?
  • Mount Kisco, N.Y. Feb. 9: 40,150 cases worldwide, 11 cases in the United States
  • Weeks earlier, Amler had started fitting employees for personal protective equipment and training them on how to use the gear. In January, she watched what was happening in Wuhan with growing concern: “It seemed impossible that it wouldn’t eventually spill out of China into the rest of the world.”
  • San Francisco Feb. 24: 79,561 cases worldwide, 51 cases in the United States
  • Trump continued to reassure the public that there was little to worry about. On Feb. 24, he tweeted, “The Coronavirus is very much under control in the USA.”
  • But Colfax and his public health staff in San Francisco were seeing something else when they studied the “curves” of the pandemic — graphs showing how many cases were reported in other regions over time.
  • Wuhan’s curve was climbing exponentially, and other countries, such as Italy, were seeing soaring infection rates as well. Colfax noticed that in every infected region, officials were more and more aggressive about restricting their populations
  • “It became apparent that no jurisdiction that was where the virus was being introduced, was sort of, in retrospect, thinking, ‘Oh, we overreacted,’ ” Colfax said.
  • On Feb. 24, Colfax and other health officials assembled their research and met with Mayor London Breed. They made an urgent request: Declare a state of emergency
  • by the end of the meeting, Breed was convinced. They needed to declare a state of emergency so that they could tap into state and federal funds and supplies, and redeploy city employees. The next day, San Francisco became one of the first major cities in the United States to do so, after Santa Clara and San Diego counties did earlier in the month.
  • It would take another 17 days, as the virus infected people in nearly every state, before Trump declared a national emergency.
  • In New Orleans, officials moved ahead with Mardi Gras festivities in late February that packed people into the streets. It was a decision the mayor would later defend as coronavirus cases traced to the celebration piled up.
  • On Feb. 27, at a White House reception, Trump predicted that the coronavirus would disappear. “Like a miracle,” he said.
  • “No red flags were given,” by the federal government, New Orleans Mayor LaToya Cantrell, a Democrat, later said in a CNN interview. “If we were given clear direction, we would not have had Mardi Gras, and I would’ve been the leader to cancel it.
  • San Antonio Feb. 29: 86,011 cases worldwide, 68 cases in the United States
  • The last day of February marked a major turning point for the coronavirus in the United States: The first American who had been diagnosed with the illness died
  • In a Saturday news conference, Trump described the patient from the Seattle area as a “medically high-risk” person who had died overnight. A CDC official said that the man, who was in his 50s, had not traveled recently — another sign that the virus was snaking through local communities.
  • During the announcement, Trump asked the media to avoid inciting panic as there was “no reason to panic at all.”
  • “We’re doing really well,” he said. “Our country is prepared for any circumstance. We hope it’s not going to be a major circumstance, it’ll be a smaller circumstance. But whatever the circumstance is, we’re prepared.”
  • That same afternoon in San Antonio, the CDC mistakenly released a woman from quarantine who was infected. The woman was one of dozens of evacuees from Wuhan whom the federal government had brought to a nearby military base and then isolated at the Texas Center for Infectious Disease.
  • the woman had been dropped off at a Holiday Inn near the San Antonio airport and headed to a mall where she shopped at Dillard’s, Talbots and Swarovski and ate in the food court.
  • As local officials learned details about the infected woman’s movements and how she had been transported at 2 a.m. back to the Texas Center for Infectious Disease, they waited for the CDC to issue a statement. Hours passed, but they heard nothing. “They were like quiet little mouses,” Wolff said. “They were all scared to talk because I think they felt they were going to get in trouble with the president of the United States because he was saying there was not a problem.”
  • The next day, San Antonio officials declared a public health emergency and filed a lawsuit to prevent the CDC from releasing the 120 people in quarantine until they were confirmed negative for the virus or completed a 28-day quarantine. A judge denied the motion, but the CDC agreed that evacuees must have two consecutive negative tests that are 24 hours apart and that no one with a pending test can be released.
  • In Oklahoma City, the coronavirus became a reality for Mayor David Holt, a Republican, when the NBA abruptly canceled a Thunder basketball game after a Utah Jazz player tested positive on March 11. Until then, Holt said, the coronavirus felt “distant on many levels.”
  • Mount Kisco, N.Y. March 3: 92,840 cases worldwide, 118 cases in the United States
  • Within days, state authorities set up an emergency operations center in New Rochelle and created a one-mile containment zone. Inside the perimeter, schools and community centers shuttered and large gatherings were prohibited.
  • Through it all, local officials faced backlash from some community leaders who thought they were overreacting.
  • San Francisco March 5: 97,886 cases worldwide, 217 cases in the United States
  • Days after San Francisco’s emergency declaration, Breed stood in front of news cameras to announce the city’s first two cases of the coronavirus.
  • They were not related, had not traveled to any coronavirus-affected areas and had no contact with known coronavirus patients: It was spreading in the community.
  • By then, Miami Mayor Francis X. Suarez, a Republican, had announced the cancellation of the Ultra Music festival, a three-day celebration that draws about 50,000 people. Miami was the first city to call off a major music festival, and Suarez faced tremendous backlash
  • When he tried to order more masks, none were immediately available. By then the entire country was scrambling for protective gear.
  • Days later, Holt huddled on the phone with other leaders from the United States Conference of Mayors. For about 20 minutes, Seattle Mayor Jenny Durkan, a Democrat, detailed the crisis seizing her city
  • “She sounded like the main character in a Stephen King novel,” Holt recalled. “She had hundreds of cases, she had dozens of deaths.”
  • “Any struggles that we’re having, whether it be testing or other issues, or even just convincing our public of the seriousness of the matter, there are some roots back to the time period in January and February, when not all national leadership was expressing how serious this was,” Holt said.
  • While the mayors held their conference call on March 13, Trump declared a national emergency to combat the coronavirus.
  • By then, Suarez had tested positive for the coronavirus and was in quarantine. As of Sunday, he remained in isolation, leading the city by phone calls and video chats. He wanted to stop flights into Miami and the governor to order residents to shelter in place as California and other states had already done.
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The Unique U.S. Failure to Control the Virus - The New York Times - 0 views

  • Already, the American death toll is of a different order of magnitude than in most other countries. With only 4 percent of the world’s population, the United States has accounted for 22 percent of coronavirus deaths. Canada, a rich country that neighbors the United States, has a per capita death rate about half as large
  • Together, the national skepticism toward collective action and the Trump administration’s scattered response to the virus have contributed to several specific failures and missed opportunities, Times reporting shows:a lack of effective travel restrictions;repeated breakdowns in testing;confusing advice about masks;a misunderstanding of the relationship between the virus and the economy;and inconsistent messages from public officials.
  • Some Republican governors have followed his lead and also played down the virus, while others have largely followed the science. Democratic governors have more reliably heeded scientific advice, but their performance in containing the virus has been uneven.
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  • In no other high-income country — and in only a few countries, period — have political leaders departed from expert advice as frequently and significantly as the Trump administration. President Trump has said the virus was not serious; predicted it would disappear; spent weeks questioning the need for masks; encouraged states to reopen even with large and growing caseloads; and promoted medical disinformation.
  • many agree that the poor results in the United States stem in substantial measure from the performance of the Trump administration.
  • “As an American, I think there is a lot of good to be said about our libertarian tradition,” Dr. Jared Baeten, an epidemiologist and vice dean at the University of Washington School of Public Health, said. “But this is the consequence — we don’t succeed as well as a collective.”
  • That tradition is one reason the United States suffers from an unequal health care system that has long produced worse medical outcomes — including higher infant mortality and diabetes rates and lower life expectancy — than in most other rich countries.
  • First, the United States faced longstanding challenges in confronting a major pandemic. It is a large country at the nexus of the global economy, with a tradition of prioritizing individualism over government restrictions.
  • The New York Times set out to reconstruct the unique failure of the United States, through numerous interviews with scientists and public health experts around the world. The reporting points to two central themes.
  • When it comes to the virus, the United States has come to resemble not the wealthy and powerful countries to which it is often compared but instead far poorer countries, like Brazil, Peru and South Africa, or those with large migrant populations, like Bahrain and Oman.
  • That’s more than five times as many as in all of Europe, Canada, Japan, South Korea and Australia, combined.
  • Over the past month, about 1.9 million Americans have tested positive for the virus.
  • one country stands alone, as the only affluent nation to have suffered a severe, sustained outbreak for more than four months: the United States.
  • Nearly every country has struggled to contain the coronavirus and made mistakes along the way.
  • it quickly became clear that the United States’ policy was full of holes. It did not apply to immediate family members of American citizens and permanent residents returning from China, for example. In the two months after the policy went into place, almost 40,000 people arrived in the United States on direct flights from China.
  • On Jan. 31, his administration announced that it was restricting entry to the United States from China: Many foreign nationals — be they citizens of China or other countries — would not be allowed into the United States if they had been to China in the previous two weeks.
  • A travel policy that fell short
  • In retrospect, one of Mr. Trump’s first policy responses to the virus appears to have been one of his most promising.
  • The administration’s policy also did little to create quarantines for people who entered the United States and may have had the virus.
  • ven more important, the policy failed to take into account that the virus had spread well beyond China by early February. Later data would show that many infected people arriving in the United States came from Europe
  • South Korea, Hong Kong and Taiwan largely restricted entry to residents returning home. Those residents then had to quarantine for two weeks upon arrival
  • South Korea and Hong Kong also tested for the virus at the airport and transferred anyone who was positive to a government facility.
  • “People need a bit more than a suggestion to look after their own health,” said Dr. Mackay, who has been working with Australian officials on their pandemic response. “They need guidelines, they need rules — and they need to be enforced.”
  • Travel restrictions and quarantines were central to the success in controlling the virus in South Korea, Hong Kong, Taiwan and Australia, as well as New Zealand, many epidemiologists believe. In Australia, the number of new cases per day fell more than 90 percent in April. It remained near zero through May and early June, even as the virus surged across much of the United States.
  • the tolls in Australia and the United States remain vastly different. Fewer than 300 Australians have died of complications from Covid-19, the illness caused by the virus. If the United States had the same per capita death rate, about 3,300 Americans would have died, rather than 158,000.
  • there is a good chance that a different version of Mr. Trump’s restrictions — one with fewer holes and stronger quarantines — would have meaningfully slowed the virus’s spread.
  • travel restrictions had been successful enough in fighting the coronavirus around the world that those views may need to be revisited.“Travel,” he said, “is the hallmark of the spread of this virus around the world.”
  • Traditionally, public health experts had not seen travel restrictions as central to fighting a pandemic, given their economic costs and the availability of other options, like testing, quarantining and contact tracing
  • But he added that
  • By early March, with the testing delays still unresolved, the New York region became a global center of the virus — without people realizing it until weeks later. More widespread testing could have made a major difference, experts said, leading to earlier lockdowns and social distancing and ultimately less sickness and death.
  • While the C.D.C. was struggling to solve its testing flaws, Germany was rapidly building up its ability to test. Chancellor Angela Merkel, a chemist by training, and other political leaders were watching the virus sweep across northern Italy, not far from southern Germany, and pushed for a big expansion of testing.
  • By the time the virus became a problem in Germany, labs around the country had thousands of test kits ready to use. From the beginning, the government covered the cost of the tests. American laboratories often charge patients about $100 for a test.
  • Without free tests, Dr. Hendrik Streeck, director of the Institute of Virology at the University Hospital Bonn, said at the time, “a young person with no health insurance and an itchy throat is unlikely to go to the doctor and therefore risks infecting more people.”
  • Germany was soon far ahead of other countries in testing. It was able to diagnose asymptomatic cases, trace the contacts of new patients and isolate people before they could spread the virus. The country has still suffered a significant outbreak. But it has had many fewer cases per capita than Italy, Spain, France, Britain or Canada — and about one-fifth the rate of the United States.
  • One measure of the continuing troubles with testing is the percentage of tests that come back positive. In a country that has the virus under control, fewer than 5 percent of tests come back positive, according to World Health Organization guidelines. Many countries have reached that benchmark. The United States, even with the large recent volume of tests, has not.
  • In Belgium recently, test results have typically come back in 48 to 72 hours. In Germany and Greece, it is two days. In France, the wait is often 24 hours.
  • The conflicting advice, echoed by the C.D.C. and others, led to relatively little mask wearing in many countries early in the pandemic. But several Asian countries were exceptions, partly because they had a tradition of mask wearing to avoid sickness or minimize the effects of pollution.
  • The double mask failure
  • By January, mask wearing in Japan was widespread, as it often had been during a typical flu season. Masks also quickly became the norm in much of South Korea, Thailand, Vietnam, Taiwan and China.
  • In the following months, scientists around the world began to report two strands of evidence that both pointed to the importance of masks: Research showed that the virus could be transmitted through droplets that hang in the air, and several studies found that the virus spread less frequently in places where people were wearing masks.
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Taiwan Is Beating the Coronavirus. Can the US Do the Same? | WIRED - 0 views

  • it is natural enough to look at Taiwan’s example and wonder why we didn’t do what they did, or, more pertinently, could we have done what they did?
  • we keep seeing the culturally embedded assumption that East Asian-style state social control just won’t fly in the good old, individualist, government-wary, freedom-loving United States.
  • The New York Times: People in “places like Singapore … are more willing to accept government orders.” Fortune: “There seems to be more of a willingness to place the community and society needs over individual liberty.” Even WIRED: “These countries all have social structures and traditions that might make this kind of surveillance and control a little easier than in the don’t-tread-on-me United States.”
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  • we see the classic “Confucian values” (or “Asian values”) argument that has historically been deployed to explain everything from the economic success of East Asian nations to the prevalence of authoritarian single-party rule in Asia, and even, most recently, China’s supposed edge in AI research.
  • So, yeah, kudos to Taiwan for keeping its people safe, but here in America we’re going to do what we always do in a crisis—line up at a gun store and accuse the opposing political party of acting in bad faith. Not for us, those Asian values.
  • But the truth is that Taiwan, one of Asia’s most vibrant and boisterous democracies, is a terrible example to cite as a cultural other populated by submissive peons
  • Taiwan’s self-confidence and collective solidarity trace back to its triumphal self-liberation from its own authoritarian past, its ability to thrive in the shadow of a massive, hostile neighbor that refuses to recognize its right to chart its own path, and its track record of learning from existential threats.
  • There is no doubt that in January it would have been difficult for the US to duplicate Taiwan’s containment strategy, but that’s not because Americans are inherently more ornery than Taiwanese
  • It’s because the United States has a miserable record when it comes to learning from its own mistakes and suffers from a debilitating lack of faith in the notion that the government can solve problems—something that dates at least as far back as the moment in 1986 when Ronald Reagan said, “The nine most terrifying words in the English language are: ‘I’m from the government and I’m here to help.’”
  • The Taiwan-US comparison is the opposite of a clash of civilizations; instead, it’s a deathly showdown between competence and incompetence.
  • To be fair, there are some cultural aspects of East Asian societies that may work in Taiwan’s favor
  • There is undeniably a long tradition in East Asia of elevating scholars and experts to the highest levels of government,
  • The country’s president Tsai Ingwen, boasts a PhD from the London School of Economics, and the vice president, Chen Chien-jen, is a highly regarded epidemiologist
  • The threat of SARS put Taiwan on high alert for future outbreaks, while the past record of success at meeting such challenges seems to have encouraged the public to accept socially intrusive technological interventions.
  • First, and most important was Taiwan’s experience battling the SARS outbreak in 2003, followed by the swine flu in 2009
  • “Taiwan actually has a functioning democratic government, run by sensible, well-educated people—the USA? Not so much.”)
  • Taiwan’s commitment to transparency has also been critical
  • In the United States, the Trump administration ordered federal health authorities to treat high-level discussions on the coronavirus as classified material.
  • In Taiwan, the government has gone to great lengths to keep citizens well informed on every aspect of the outbreak, including daily press conferences and an active presence on social media
  • “Do not forget that Taiwan has been under China’s threat constantly,” wrote Wang Cheng-hua, a professor of art history at Princeton, “which has raised social consciousness about collective action. When the collective will supports government, then all of the strict measures implemented by the government make sense.”
  • Over the past quarter-century, Taiwan’s government has nurtured public trust by its actions and its transparency.
  • The democracy activists who risked their lives and careers during the island nation’s martial law era were not renowned for their willingness to accept government orders or preach Confucian social harmony
  • some of the current willingness to trust what the government is telling the people is the direct “result of having experienced the transition from an authoritarian government that lied all the time, to a democratic government and robust political dialogue that forced people to be able to evaluate information.”
  • Because of the opposition of the People’s Republic of China, Taiwan is not a member of the United Nations or the World Health Organization
  • “The reality of being isolated from global organizations,” wrote Tung, “also makes Taiwanese very aware of the publicity of its success in handling a crisis like this. The more coverage from foreign media, the more people feel confident in government policy and social mobilization.”
  • Given what we know about Taiwan’s hard-won historical experience, could the US have implemented a similar model?
  • The answer, sadly, seems to be no
  • it would be impossible for the US to successfully integrate a health care database with customs and travel records because there is no national health care database in the United States. “The US health care system is fragmented, making it difficult to organize, integrate, and assess data coming in from its various government and private-sector parts,”
  • more tellingly, continued Fidler, “the manner in which the United States has responded to Covid-19 demonstrates that the United States did not learn the lessons from past outbreaks and is struggling to cobble together a semblance of a strategy. ”
  • There’s where the contrast between the United States and Taiwan becomes most salient. The US is not only bad at the act of government but has actively been getting worse.
  • But Taiwan’s own success at building a functional democracy is probably the most potent rebuke to the Asian values thesis.
  • But over that same period, powerful political and economic interests in the US have dedicated themselves to undermining faith in government action, in favor of deregulated markets that have no capacity to react intelligently or proactively to existential threats.
  • And instead of learning from history, US leaders actively ignore it, a truth for which there could be no better symbolic proof than the Trump administration’s dismantling of the National Security Council pandemic office created by the Obama administration in the wake of the Ebola outbreak
  • Finally, instead of seeking to keep the public informed to the best of our ability, some of our political leaders and media institutions have gone out of their way to muddy the waters.
  • In Taiwan, one early government response to the Covid-19 outbreak was to institute a fine of $100,000 for the act of spreading fake news about the epidemic.
  • In the US the most popular television news network in the country routinely downplayed or misrepresented the threat of the coronavirus, until the severity of the outbreak became too large to ignore.
  • If there is any silver lining here, it’s that the disaster now upon us is of such immense scope that it could finally expose the folly of the structural forces that have been wreaking sustained havoc on American governmental institutions
  • So maybe we are finally about to learn that competence matters, that educated leaders are a virtue, and that telling the truth is a responsibility
  • Americans might have to learn this the hard way, like we did in Hong Kong and Singapore.”
  • We’re about to find out how hard it’s going to be. But will we learn?
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The Coronavirus Could End American Exceptionalism - The Atlantic - 0 views

  • many American politicians, especially those on the right, have in recent years paradoxically doubled down on American exceptionalism (we have a president who ran on an “America first” platform, after all) even as American power has declined relative to other countries’.
  • This kind of insularity might have been “relatively harmless when America bestrode the world like a colossus, but it’s dangerous when the country faces a raft of global challenges from China, to climate, to COVID-19,” Dominic Tierney, a political-science professor at Swarthmore College
  • Pandemics are, in fact, particularly ripe moments for cross-cultural learning
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  • Today, in the case of COVID-19, “all states face the same essential threat, and each government’s response is a kind of laboratory experiment,” Tierney said.
  • “The United States had the advantage of being struck relatively late by the virus, and this gave [us] a priceless chance to copy best practices and avoid the mistakes of others,” he noted.
  • When China began confining millions of people to their homes in January, the U.S. government should have gotten the message that the Chinese were grappling with a grave threat to the wider world, the Yale sociologist and physician Nicholas Christakis told me in March.
  • We lost six weeks” in the United States to prepare—“to build ventilators, get protective equipment, organize our ICUs, get tests ready, prepare the public for what was going to happen so that our economy didn’t tank as badly. None of this was done adequately by our leaders.”
  • By one estimate, from the epidemiologists Britta L. Jewell and Nicholas P. Jewell, if social-distancing policies had been implemented just two weeks earlier in March, 90 percent of the cumulative coronavirus deaths in the United States during the first wave of the pandemic might have been prevented.
  • Rather than using diagnostic tests that the World Health Organization had distributed to other countries early in the global outbreak, the Centers for Disease Control and Prevention insisted on developing its own, only to botch the rollout of those tests.
  • Even now, as a number of countries have swum feverishly toward safer ground, the United States has spent the past couple of months of near-nationwide lockdown merely treading water. It has yet to roll out robust testing across the country
  • It has also failed to develop proper contact-tracing systems, as other nations have, and to meaningfully flatten the curve outside New York.
  • Amid all this, Trump has exhibited more hubris than humility. The president has repeatedly claimed that the United States is leading the world in testing, which in part is an unflattering reflection of the U.S. outbreak’s huge scale and also is not true on a per-capita basis
  • As an example of ideas the United States could borrow from other countries, Tierney cited the fact that 750,000 people in Britain, which would be equivalent to nearly 4 million Americans, responded to the British government’s request to enlist in a “volunteer army” to help deliver food to vulnerable populations and provide other assistance.
  • A number of countries that have had more success against the coronavirus have demonstrated greater open-mindedness about learning from their peers. Taiwanese officials are watching Iceland’s mass-testing efforts, while the German government is explicitly modeling its response after South Korea’s “trace, test, and treat” campaign.
  • “Things have moved so quickly that there hasn't been much time for considered lesson-drawing,” he noted. Some countries were slow to institute strict lockdowns, despite witnessing the horrifying spread of the virus in Italy, while others “embraced approaches that broke with the broader consensus,” including “Sweden’s proposal
  • New Zealand’s record of learning
  • His colleague at the University of Otago, Michael Baker, told me that as a government adviser on the nation’s coronavirus taskforce, he was personally very influenced by a February 2020 WHO-China Joint Mission report, which suggested that the pandemic could be contained, and led him to advocate for New Zealand’s current strategy of eliminating the virus entirely from the country.
  • Yet Wilson added that New Zealand has lagged behind Asian countries in encouraging mass mask wearing, in rigorously quarantining incoming travelers, and in using digital technologies for contact tracing
  • In the United States too, even before the virus hit, attitudes toward learning from other countries were beginning to change
  • “The No. 1 place to live out the American Dream right now is Denmark,” Pete Buttigieg stated during one debate.
  • as a senator, Romney is urging the U.S. government to follow South Korea’s lead and “learn from those countries that were successful” in dealing with their outbreaks. Conservatives are championing Sweden’s laissez-faire approach as a blueprint for how to mitigate public-health damage while preserving freedom and the economy.
  • with the exception of the U.S. Paycheck Protection Program, “most of our economic-policy response has ignored useful lessons from abroad, explaining why our unemployment rate is skyrocketing above those in many other affected countries.”
  • Kelemen noted that the coronavirus crisis has led to a surge in interest among the American public and U.S. policy makers in harvesting lessons from other countries, most evident in the fact that everyone is following “the comparative charts of how countries are doing over time on infection rates or changes in year-on-year death counts.
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How Will the Coronavirus End? - The Atlantic - 0 views

  • A global pandemic of this scale was inevitable. In recent years, hundreds of health experts have written books, white papers, and op-eds warning of the possibility. Bill Gates has been telling anyone who would listen, including the 18 million viewers of his TED Talk.
  • We realized that her child might be one of the first of a new cohort who are born into a society profoundly altered by COVID-19. We decided to call them Generation C.
  • “No matter what, a virus [like SARS-CoV-2] was going to test the resilience of even the most well-equipped health systems,”
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  • To contain such a pathogen, nations must develop a test and use it to identify infected people, isolate them, and trace those they’ve had contact with. That is what South Korea, Singapore, and Hong Kong did to tremendous effect. It is what the United States did not.
  • That a biomedical powerhouse like the U.S. should so thoroughly fail to create a very simple diagnostic test was, quite literally, unimaginable. “I’m not aware of any simulations that I or others have run where we [considered] a failure of testing,”
  • The testing fiasco was the original sin of America’s pandemic failure, the single flaw that undermined every other countermeasure. If the country could have accurately tracked the spread of the virus, hospitals could have executed their pandemic plans, girding themselves by allocating treatment rooms, ordering extra supplies, tagging in personnel, or assigning specific facilities to deal with COVID-19 cases.
  • None of that happened. Instead, a health-care system that already runs close to full capacity, and that was already challenged by a severe flu season, was suddenly faced with a virus that had been left to spread, untracked, through communities around the country.
  • With little room to surge during a crisis, America’s health-care system operates on the assumption that unaffected states can help beleaguered ones in an emergency.
  • That ethic works for localized disasters such as hurricanes or wildfires, but not for a pandemic that is now in all 50 states. Cooperation has given way to competition
  • Partly, that’s because the White House is a ghost town of scientific expertise. A pandemic-preparedness office that was part of the National Security Council was dissolved in 2018. On January 28, Luciana Borio, who was part of that team, urged the government to “act now to prevent an American epidemic,” and specifically to work with the private sector to develop fast, easy diagnostic tests. But with the office shuttered, those warnings were published in The Wall Street Journal, rather than spoken into the president’s ear.
  • Rudderless, blindsided, lethargic, and uncoordinated, America has mishandled the COVID-19 crisis to a substantially worse degree than what every health expert I’ve spoken with had feared. “Much worse,”
  • “Beyond any expectations we had,” said Lauren Sauer, who works on disaster preparedness at Johns Hopkins Medicine. “As an American, I’m horrified,” said Seth Berkley, who heads Gavi, the Vaccine Alliance. “The U.S. may end up with the worst outbreak in the industrialized world.”
  • it will be difficult—but not impossible—for the United States to catch up. To an extent, the near-term future is set because COVID-19 is a slow and long illness. People who were infected several days ago will only start showing symptoms now, even if they isolated themselves in the meantime. Some of those people will enter intensive-care units in early April
  • A “massive logistics and supply-chain operation [is] now needed across the country,” says Thomas Inglesby of Johns Hopkins Bloomberg School of Public Health. That can’t be managed by small and inexperienced teams scattered throughout the White House. The solution, he says, is to tag in the Defense Logistics Agency—a 26,000-person group that prepares the U.S. military for overseas operations and that has assisted in past public-health crises, including the 2014 Ebola outbreak.
  • The first and most important is to rapidly produce masks, gloves, and other personal protective equipment
  • it would also come at a terrible cost: SARS-CoV-2 is more transmissible and fatal than the flu, and it would likely leave behind many millions of corpses and a trail of devastated health systems.
  • This agency can also coordinate the second pressing need: a massive rollout of COVID-19 tests.
  • These measures will take time, during which the pandemic will either accelerate beyond the capacity of the health system or slow to containable levels. Its course—and the nation’s fate—now depends on the third need, which is social distancing.
  • There are now only two groups of Americans. Group A includes everyone involved in the medical response, whether that’s treating patients, running tests, or manufacturing supplies. Group B includes everyone else, and their job is to buy Group A more time. Group B must now “flatten the curve” by physically isolating themselves from other people to cut off chains of transmission.
  • Given the slow fuse of COVID-19, to forestall the future collapse of the health-care system, these seemingly drastic steps must be taken immediately, before they feel proportionate, and they must continue for several weeks.
  • Persuading a country to voluntarily stay at home is not easy, and without clear guidelines from the White House, mayors, governors, and business owners have been forced to take their own steps.
  • when the good of all hinges on the sacrifices of many, clear coordination matters—the fourth urgent need
  • Pundits and business leaders have used similar rhetoric, arguing that high-risk people, such as the elderly, could be protected while lower-risk people are allowed to go back to work. Such thinking is seductive, but flawed. It overestimates our ability to assess a person’s risk, and to somehow wall off the ‘high-risk’ people from the rest of society. It underestimates how badly the virus can hit ‘low-risk’ groups, and how thoroughly hospitals will be overwhelmed if even just younger demographics are falling sick.
  • A recent analysis from the University of Pennsylvania estimated that even if social-distancing measures can reduce infection rates by 95 percent, 960,000 Americans will still need intensive care.
  • There are only about 180,000 ventilators in the U.S. and, more pertinently, only enough respiratory therapists and critical-care staff to safely look after 100,000 ventilated patients. Abandoning social distancing would be foolish. Abandoning it now, when tests and protective equipment are still scarce, would be catastrophic.
  • If Trump stays the course, if Americans adhere to social distancing, if testing can be rolled out, and if enough masks can be produced, there is a chance that the country can still avert the worst predictions about COVID-19, and at least temporarily bring the pandemic under control. No one knows how long that will take, but it won’t be quick. “It could be anywhere from four to six weeks to up to three months,” Fauci said, “but I don’t have great confidence in that range.”
  • there are three possible endgames: one that’s very unlikely, one that’s very dangerous, and one that’s very long.
  • The first is that every nation manages to simultaneously bring the virus to heel, as with the original SARS in 2003. Given how widespread the coronavirus pandemic is, and how badly many countries are faring, the odds of worldwide synchronous control seem vanishingly small.
  • The second is that the virus does what past flu pandemics have done: It burns through the world and leaves behind enough immune survivors that it eventually struggles to find viable hosts. This “herd immunity” scenario would be quick, and thus tempting
  • The U.S. has fewer hospital beds per capita than Italy. A study released by a team at Imperial College London concluded that if the pandemic is left unchecked, those beds will all be full by late April. By the end of June, for every available critical-care bed, there will be roughly 15 COVID-19 patients in need of one.  By the end of the summer, the pandemic will have directly killed 2.2 million Americans,
  • The third scenario is that the world plays a protracted game of whack-a-mole with the virus, stamping out outbreaks here and there until a vaccine can be produced. This is the best option, but also the longest and most complicated.
  • there are no existing vaccines for coronaviruses—until now, these viruses seemed to cause diseases that were mild or rare—so researchers must start from scratch.
  • The first steps have been impressively quick. Last Monday, a possible vaccine created by Moderna and the National Institutes of Health went into early clinical testing. That marks a 63-day gap between scientists sequencing the virus’s genes for the first time and doctors injecting a vaccine candidate into a person’s arm. “It’s overwhelmingly the world record,” Fauci said.
  • The initial trial will simply tell researchers if the vaccine seems safe, and if it can actually mobilize the immune system. Researchers will then need to check that it actually prevents infection from SARS-CoV-2. They’ll need to do animal tests and large-scale trials to ensure that the vaccine doesn’t cause severe side effects. They’ll need to work out what dose is required, how many shots people need, if the vaccine works in elderly people, and if it requires other chemicals to boost its effectiveness.
  • No matter which strategy is faster, Berkley and others estimate that it will take 12 to 18 months to develop a proven vaccine, and then longer still to make it, ship it, and inject it into people’s arms.
  • as the status quo returns, so too will the virus. This doesn’t mean that society must be on continuous lockdown until 2022. But “we need to be prepared to do multiple periods of social distancing,” says Stephen Kissler of Harvard.
  • First: seasonality. Coronaviruses tend to be winter infections that wane or disappear in the summer. That may also be true for SARS-CoV-2, but seasonal variations might not sufficiently slow the virus when it has so many immunologically naive hosts to infect.
  • Second: duration of immunity. When people are infected by the milder human coronaviruses that cause cold-like symptoms, they remain immune for less than a year. By contrast, the few who were infected by the original SARS virus, which was far more severe, stayed immune for much longer.
  • scientists will need to develop accurate serological tests, which look for the antibodies that confer immunity. They’ll also need to confirm that such antibodies actually stop people from catching or spreading the virus. If so, immune citizens can return to work, care for the vulnerable, and anchor the economy during bouts of social distancing.
  • Aspects of America’s identity may need rethinking after COVID-19. Many of the country’s values have seemed to work against it during the pandemic. Its individualism, exceptionalism, and tendency to equate doing whatever you want with an act of resistance meant that when it came time to save lives and stay indoors, some people flocked to bars and clubs.
  • “We can keep schools and businesses open as much as possible, closing them quickly when suppression fails, then opening them back up again once the infected are identified and isolated. Instead of playing defense, we could play more offense.”
  • The vaccine may need to be updated as the virus changes, and people may need to get revaccinated on a regular basis, as they currently do for the flu. Models suggest that the virus might simmer around the world, triggering epidemics every few years or so. “But my hope and expectation is that the severity would decline, and there would be less societal upheaval,”
  • After infections begin ebbing, a secondary pandemic of mental-health problems will follow.
  • But “there is also the potential for a much better world after we get through this trauma,”
  • Testing kits can be widely distributed to catch the virus’s return as quickly as possible. There’s no reason that the U.S. should let SARS-CoV-2 catch it unawares again, and thus no reason that social-distancing measures need to be deployed as broadly and heavy-handedly as they now must be.
  • Pandemics can also catalyze social change. People, businesses, and institutions have been remarkably quick to adopt or call for practices that they might once have dragged their heels on, including working from home, conference-calling to accommodate people with disabilities, proper sick leave, and flexible child-care arrangements.
  • Perhaps the nation will learn that preparedness isn’t just about masks, vaccines, and tests, but also about fair labor policies and a stable and equal health-care system. Perhaps it will appreciate that health-care workers and public-health specialists compose America’s social immune system, and that this system has been suppressed.
  • Attitudes to health may also change for the better. The rise of HIV and AIDS “completely changed sexual behavior among young people who were coming into sexual maturity at the height of the epidemic,”
  • Years of isolationist rhetoric had consequences too.
  • “People believed the rhetoric that containment would work,” says Wendy Parmet, who studies law and public health at Northeastern University. “We keep them out, and we’ll be okay. When you have a body politic that buys into these ideas of isolationism and ethnonationalism, you’re especially vulnerable when a pandemic hits.”
  • Pandemics are democratizing experiences. People whose privilege and power would normally shield them from a crisis are facing quarantines, testing positive, and losing loved ones. Senators are falling sick. The consequences of defunding public-health agencies, losing expertise, and stretching hospitals are no longer manifesting as angry opinion pieces, but as faltering lungs.
  • After COVID-19, attention may shift to public health. Expect to see a spike in funding for virology and vaccinology, a surge in students applying to public-health programs, and more domestic production of medical supplies.
  • The lessons that America draws from this experience are hard to predict, especially at a time when online algorithms and partisan broadcasters only serve news that aligns with their audience’s preconceptions.
  • “The transitions after World War II or 9/11 were not about a bunch of new ideas,” he says. “The ideas are out there, but the debates will be more acute over the next few months because of the fluidity of the moment and willingness of the American public to accept big, massive changes.”
  • One could easily conceive of a world in which most of the nation believes that America defeated COVID-19. Despite his many lapses, Trump’s approval rating has surged. Imagine that he succeeds in diverting blame for the crisis to China, casting it as the villain and America as the resilient hero.
  • One could also envisage a future in which America learns a different lesson. A communal spirit, ironically born through social distancing, causes people to turn outward, to neighbors both foreign and domestic. The election of November 2020 becomes a repudiation of “America first” politics. The nation pivots, as it did after World War II, from isolationism to international cooperation
  • The U.S. leads a new global partnership focused on solving challenges like pandemics and climate change.
  • In 2030, SARS-CoV-3 emerges from nowhere, and is brought to heel within a month.
  • On the Global Health Security Index, a report card that grades every country on its pandemic preparedness, the United States has a score of 83.5—the world’s highest. Rich, strong, developed, America is supposed to be the readiest of nations. That illusion has been shattered. Despite months of advance warning as the virus spread in other countries, when America was finally tested by COVID-19, it failed.
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Tests Show Genetic Signature of Coronavirus That Likely Infected Trump - The New York T... - 0 views

  • President Trump’s illness from a coronavirus infection last month was the most significant health crisis for a sitting president in nearly 40 years. Yet little remains known about how the virus arrived at the White House and how it spread
  • The administration did not take basic steps to track the outbreak, limiting contact tracing, keeping cases a secret and cutting out the Centers for Disease Control and Prevention. The origin of the infections, a spokesman said, was “unknowable.”
  • The journalists, Michael D. Shear and Al Drago, both had significant, separate exposure to White House officials in late September, several days before they developed symptoms. They did not spend any time near each other in the weeks before their positive tests.
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  • The study reveals, for the first time, the genetic sequence of the virus that may have infected Mr. Trump and dozens of others, researchers said.
  • In a study released on Thursday, the C.D.C. cited genetic sequencing and intensive contact tracing that documented an super-spreading event at a high school retreat in Wisconsin.
  • The genomes believed by these researchers to be connected to the White House outbreak do not identify a recent geographic source, in part because they are unusual.
  • The results show that even weeks after it was identified, the White House outbreak would be better understood by sequencing samples of more people who were infected.
  • Viruses constantly mutate, picking up tiny, accidental alterations to their genetic material as they reproduce. Few mutations alter how a virus functions. But by comparing patterns of mutations across many genetic sequences, scientists can construct family trees of a virus, illuminating how it spreads.
  • But the Trump administration is not known to have conducted its own genetic analysis of people infected in the outbreak. The White House declined to respond to questions on genetic sequencing of Mr. Trump and the cluster of aides and officials who tested positive or became ill.
  • Scientists not involved in the research who reviewed the results agreed with the conclusion that the two samples sharing rare mutations strongly suggested they are part of the same outbreak.
  • “These genomes are probably going to be identical or nearly identical to the genome that infected the president,” said Michael Worobey, head of the department of ecology and evolutionary biology at the University of Arizona.
  • For months, the White House minimized the threat of the virus and eschewed basic safety precautions at official events, like wearing a mask or keeping people six feet apart.
  • At least 11 people who attended a Rose Garden celebration on Sept. 26 for Judge Barrett, which included an indoor event without masks, became infected with the coronavirus, including Mr. Trump.
  • The work is convincing, and it is the best way to piece together the progression of such an outbreak, said David Engelthaler, head of the infectious disease branch of the Translational Genomics Research Institute in Arizona, where he and colleagues have sequenced thousands of genomes to track the spread of the coronavirus, including devastating outbreaks at Native American reservations in the state.
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How South Korea Successfully Managed Coronavirus - WSJ - 0 views

  • South Korea appears to have cracked the code for managing the coronavirus. Its solution is straightforward, flexible and relatively easy to replicate.
  • The country has averaged about 77 new daily cases since early April and recently suppressed a spike in infections. Adjusting for population, that would be the equivalent of about 480 cases a day in the U.S., where new daily cases have averaged about 38,000 over the same period.
  • South Korea halted virus transmission better than any other wealthy country during the pandemic’s early months. It was about twice as effective as the U.S. and U.K. at preventing infected individuals from spreading the disease to other
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  • South Korea’s economy is expected to decline by just 0.8% this year, the best among the Organization for Economic Cooperation and Development’s forecasts for member nations.
  • When the supply of face masks ran short early on in the crisis, the government seized production.
  • The nation fast-tracked approval of domestic testing kits as soon as cases began hitting
  • It tapped into its relative wealth and hyperconnectivity, blasting text alerts to citizens if infections occurred in their area
  • The key to South Korea’s success came from blending technology and testing like no other country, centralized control and communication—and a constant fear of failure.
  • “You don’t need or want to eradicate the virus. But you modify your behavior and get on with life.”
  • Nearly everyone in the country wears masks.
  • Every confirmed patient, even those with no or mild symptoms, gets isolated at hospitals or converted dormitories run by the government. Treatment is free.
  • As a result, South Korea never had to mandate a lockdown, so restaurants and business were able to stay open, cushioning the blow to the economy.
  • “No country has adapted to living with, and containing, the virus like South Korea,”
  • Some parts of its playbook wouldn’t work in most Western societies—and received backlash in South Korea as well
  • It detected the country’s first case 10 days later using a test that screened for all known coronavirus strains—the same tactic practiced during the December simulation.
  • Health officials have unfettered access to individuals’ private mobile data, and early on used government websites to share the whereabouts of confirmed patients, plucked from smartphone GPS history
  • The government now offers anonymous testing and leaves out identifying information and specific names of places visited in contact-tracing disclosures.
  • After a major cluster linked to a megachurch in the city of Daegu emerged on Feb. 18, the government made a flurry of moves
  • Cases peaked in 11 days.
  • The day after cases reached a five-month high of 441 on Aug. 27, South Korea’s top public-health official gave a grim forecast: “We could see 800 to 2,000 infections next week
  • South Koreans took the advice and adjusted. Population mobility, as measured by local telecom operators, soon fell by one-quarter. Most schools closed and diners had to leave restaurants by 9 p.m. Aug. 27 turned out to be the peak.
  • After two weeks of aggressive social distancing, South Koreans could again head back to schools, gyms and sports stadiums.
  • In total, South Korea, with a population of 52 million, has reported 23,455 cases and 395 deaths.
  • One reason South Korea was prepared: It learned painful lessons in 2015 from an outbreak of Middle East respiratory syndrome
  • “The only way to make the government prepared is to actually have an outbreak,”
  • After MERS, the government started twice-a-year training sessions simulating a rapid spread of viral disease
  • “Oddly enough, last December’s ‘war game’ was a novel coronavirus,”
  • At twice-a-day briefings, health officials express worry when they can only trace the origins of three-quarters of confirmed cases.
  • One firm, Kogene Biotech Co., demonstrated a successful test and got the regulatory green light within four days. A second manufacturer would be added by Feb. 12. The tests all used the same methodology and could be sent to any of the country’s roughly 120 laboratories that promised turnaround times of between six to 24 hours.
  • Cases, which had been slowly rising, suddenly doubled in a day, to over 100. Experts predicted it would soon surge to levels seen nowhere else but China.
  • That triggered a Feb. 20 late-night message in a group chat with eight South Korean infectious-disease experts: “We need to quickly devise a way to conduct mass testing,”
  • an answer: drive-through clinics.
  • Dr. Kim sent a PowerPoint presentation to the group within hours, at 3:53 a.m., outlining how tests would take just 10 minutes and saved much-needed protective gear since outdoor workers didn’t have to change gowns after each patient
  • Two days later, cars rumbled through the country’s first drive-through clinic. Testing capacity multiplied 100 times, giving South Korea a critical early edge.
  • As South Korea’s coronavirus problems mounted, Mr. Moon intentionally kept his profile low. “His stance is that it’s more objective for an expert to hold the briefings, and that is the way to gain the trust of the people,”
  • Even with the swift response, a lack of hospital beds became a major issue. In just 11 days, South Korea’s case count had gone from 31 to 3,150. Thousands were waiting to be hospitalized. A handful died while waiting.
  • South Korea’s infectious-disease experts had a proposal. Confirmed patients should be divided into four categories, based on the risk profile and severity of symptoms, with only the most serious cases hospitalized. Those with mild or no symptoms should be isolated at makeshift treatment facilities.
  • Dr. Peck set up a meeting with senior officials from the Samsung conglomerate, asking that an empty facility near Daegu be lent to the South Korean government. By first having a company volunteer a venue, Dr. Peck recalled thinking, it would pressure South Korea’s health ministry to act.
  • About 80% of South Korea’s coronavirus patients have been hospitalized in the community treatment centers. Those who are asymptomatic or have mild symptoms are still sent there.
  • That changed in August. Unlike February’s outbreak, the new wave of infections fanned out across South Korea to all 15 of the country’s major cities and provinces. The country’s national testing capacity had by then expanded to 50,000 a day with test results notified within 24 hours, up from 20,000 in February
  • The U.S. conducted about 900,000 tests a day over the past week through Thursday, according to data from the Covid Tracking Project. But South Korea performs six times as many tests per confirmed Covid-19 case than the U.S. doe
  • South Korea’s three-tier system created in June for social distancing went off script. With health experts split on whether to adopt the maximum levels last month, a government advisory committee landed at a “level 2.5” social-distancing for the Seoul area that closed schools and banned church services and gatherings of more than 10 people.
  • On Tuesday, South Korea reported its lowest one-day infections in over a month, with just 61 cases.
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The Coronavirus Can Be Stopped, but Only With Harsh Steps, Experts Say - The New York T... - 0 views

  • Terrifying though the coronavirus may be, it can be turned back. China, South Korea, Singapore and Taiwan have demonstrated that, with furious efforts, the contagion can be brought to heel.
  • for the United States to repeat their successes will take extraordinary levels of coordination and money from the country’s leaders, and extraordinary levels of trust and cooperation from citizens. It will also require international partnerships in an interconnected world.
  • This contagion has a weakness.
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  • the coronavirus more often infects clusters of family members, friends and work colleagues,
  • “You can contain clusters,” Dr. Heymann said. “You need to identify and stop discrete outbreaks, and then do rigorous contact tracing.”
  • The microphone should not even be at the White House, scientists said, so that briefings of historic importance do not dissolve into angry, politically charged exchanges with the press corps, as happened again on Friday.
  • Americans must be persuaded to stay home, they said, and a system put in place to isolate the infected and care for them outside the home
  • Travel restrictions should be extended, they said; productions of masks and ventilators must be accelerated, and testing problems must be resolved.
  • It was not at all clear that a nation so fundamentally committed to individual liberty and distrustful of government could learn to adapt to many of these measures, especially those that smack of state compulsion.
  • What follows are the recommendations offered by the experts interviewed by The Times.
  • they were united in the opinion that politicians must step aside and let scientists both lead the effort to contain the virus and explain to Americans what must be done.
  • medical experts should be at the microphone now to explain complex ideas like epidemic curves, social distancing and off-label use of drugs.
  • doing so takes intelligent, rapidly adaptive work by health officials, and near-total cooperation from the populace. Containment becomes realistic only when Americans realize that working together is the only way to protect themselves and their loved ones.
  • Above all, the experts said, briefings should focus on saving lives and making sure that average wage earners survive the coming hard times — not on the stock market, the tourism industry or the president’s health.
  • “At this point in the emergency, there’s little merit in spending time on what we should have done or who’s at fault,”
  • The next priority, experts said, is extreme social distancing.If it were possible to wave a magic wand and make all Americans freeze in place for 14 days while sitting six feet apart, epidemiologists say, the whole epidemic would sputter to a halt.
  • The virus would die out on every contaminated surface and, because almost everyone shows symptoms within two weeks, it would be evident who was infected. If we had enough tests for every American, even the completely asymptomatic cases could be found and isolated.
  • The crisis would be over.
  • Obviously, there is no magic wand, and no 300 million tests. But the goal of lockdowns and social distancing is to approximate such a total freeze.
  • In contrast to the halting steps taken here, China shut down Wuhan — the epicenter of the nation’s outbreak — and restricted movement in much of the country on Jan. 23, when the country had a mere 500 cases and 17 deaths.Its rapid action had an important effect: With the virus mostly isolated in one province, the rest of China was able to save Wuhan.
  • Even as many cities fought their own smaller outbreaks, they sent 40,000 medical workers into Wuhan, roughly doubling its medical force.
  • Stop transmission within cities
  • the weaker the freeze, the more people die in overburdened hospitals — and the longer it ultimately takes for the economy to restart.
  • People in lockdown adapt. In Wuhan, apartment complexes submit group orders for food, medicine, diapers and other essentials. Shipments are assembled at grocery warehouses or government pantries and dropped off. In Italy, trapped neighbors serenade one another.
  • Each day’s delay in stopping human contact, experts said, creates more hot spots, none of which can be identified until about a week later, when the people infected there start falling ill.
  • South Korea avoided locking down any city, but only by moving early and with extraordinary speed. In January, the country had four companies making tests, and as of March 9 had tested 210,000 citizens — the equivalent of testing 2.3 million Americans.
  • As of the same date, fewer than 9,000 Americans had been tested.
  • Fix the testing mess
  • Testing must be done in a coordinated and safe way, experts said. The seriously ill must go first, and the testers must be protected.In China, those seeking a test must describe their symptoms on a telemedicine website. If a nurse decides a test is warranted, they are directed to one of dozens of “fever clinics” set up far from all other patients.
  • Isolate the infected
  • As soon as possible, experts said, the United States must develop an alternative to the practice of isolating infected people at home, as it endangers families. In China, 75 to 80 percent of all transmission occurred in family clusters.
  • Cellphone videos from China show police officers knocking on doors and taking temperatures. In some, people who resist are dragged away by force. The city of Ningbo offered bounties of $1,400 to anyone who turned in a coronavirus sufferer.
  • In China, said Dr. Bruce Aylward, leader of the World Health Organization’s observer team there, people originally resisted leaving home or seeing their children go into isolation centers with no visiting rights — just as Americans no doubt would.
  • In China, they came to accept it.“They realized they were keeping their families safe,” he said. “Also, isolation is really lonely. It’s psychologically difficult. Here, they were all together with other people in the same boat. They supported each other.”
  • Find the fevers
  • Make masks ubiquitous
  • In China, having a fever means a mandatory trip to a fever clinic to check for coronavirus. In the Wuhan area, different cities took different approaches.
  • In most cities in affected Asian countries, it is commonplace before entering any bus, train or subway station, office building, theater or even a restaurant to get a temperature check. Washing your hands in chlorinated water is often also required.
  • The city of Qianjiang, by contrast, offered the same amount of money to any resident who came in voluntarily and tested positive
  • Voluntary approaches, like explaining to patients that they will be keeping family and friends safe, are more likely to work in the West, she added.
  • Trace the contacts
  • Finding and testing all the contacts of every positive case is essential, experts said. At the peak of its epidemic, Wuhan had 18,000 people tracking down individuals who had come in contact with the infected.
  • Dr. Borio suggested that young Americans could use their social networks to “do their own contact tracing.” Social media also is used in Asia, but in different ways
  • When he lectured at a Singapore university, Dr. Heymann said, dozens of students were in the room. But just before he began class, they were photographed to record where everyone sat.
  • Instead of a policy that advises the infected to remain at home, as the Centers for Disease and Prevention now does, experts said cities should establish facilities where the mildly and moderately ill can recuperate under the care and observation of nurses.
  • There is very little data showing that flat surgical masks protect healthy individuals from disease. Nonetheless, Asian countries generally make it mandatory that people wear them.
  • The Asian approach is less about data than it is about crowd psychology, experts explained.All experts agree that the sick must wear masks to keep in their coughs. But if a mask indicates that the wearer is sick, many people will be reluctant to wear one. If everyone is required to wear masks, the sick automatically have one on and there is no stigma attached.
  • Also, experts emphasized, Americans should be taught to take seriously admonitions to stop shaking hands and hugging
  • Preserve vital services
  • Only the federal government can enforce interstate commerce laws to ensure that food, water, electricity, gas, phone lines and other basic needs keep flowing across state lines to cities and suburbs
  • “I sense that most people — and certainly those in business — get it. They would prefer to take the bitter medicine at once and contain outbreaks as they start rather than gamble with uncertainty.”
  • Produce ventilators and oxygen
  • The manufacturers, including a dozen in the United States, say there is no easy way to ramp up production quickly. But it is possible other manufacturers, including aerospace and automobile companies, could be enlisted to do so.
  • Canadian nurses are disseminating a 2006 paper describing how one ventilator can be modified to treat four patients simultaneously. Inventors have proposed combining C-PAP machines, which many apnea sufferers own, and oxygen tanks to improvise a ventilator.
  • One of the lessons of China, he noted, was that many Covid-19 patients who would normally have been intubated and on ventilators managed to survive with oxygen alone.
  • Retrofit hospitals
  • In Wuhan, the Chinese government famously built two new hospitals in two weeks. All other hospitals were divided: 48 were designated to handle 10,000 serious or critical coronavirus patients, while others were restricted to handling emergencies like heart attacks and births.
  • Wherever that was impractical, hospitals were divided into “clean” and “dirty” zones, and the medical teams did not cross over. Walls to isolate whole wards were built
  • Decide when to close schools
  • Recruit volunteers
  • China’s effort succeeded, experts said, in part because of hundreds of thousands of volunteers. The government declared a “people’s war” and rolled out a “Fight On, Wuhan! Fight On, China!” campaign.
  • Many people idled by the lockdowns stepped up to act as fever checkers, contact tracers, hospital construction workers, food deliverers, even babysitters for the children of first responders, or as crematory workers.
  • “In my experience, success is dependent on how much the public is informed and participates,” Admiral Ziemer said. “This truly is an ‘all hands on deck’ situation.”
  • Prioritize the treatments
  • Clinicians in China, Italy and France have thrown virtually everything they had in hospital pharmacies into the fight, and at least two possibilities have emerged that might save patients: the anti-malaria drugs chloroquine and hydroxychloroquine, and the antiviral remdesivir, which has no licensed use.
  • An alternative is to harvest protective antibodies from the blood of people who have survived the illness,
  • The purified blood serum — called immunoglobulin — could possibly be used in small amounts to protect emergency medical workers, too.
  • “Unfortunately, the first wave won’t benefit from this,” Dr. Hotez said. “We need to wait until we have enough survivors.”Find a vaccine
  • testing those candidate vaccines for safety and effectiveness takes time.
  • The roadblock, vaccine experts explained, is not bureaucratic. It is that the human immune system takes weeks to produce antibodies, and some dangerous side effects can take weeks to appear.
  • After extensive animal testing, vaccines are normally given to about 50 healthy human volunteers to see if they cause any unexpected side effects and to measure what dose produces enough antibodies to be considered protective.
  • If that goes well, the trial enrolls hundreds or thousands of volunteers in an area where the virus is circulating. Half get the vaccine, the rest do not — and the investigators wait. If the vaccinated half do not get the disease, the green light for production is finally given.
  • In the past, some experimental vaccines have produced serious side effects, like Guillain-Barre syndrome, which can paralyze and kill. A greater danger, experts said, is that some experimental vaccines, paradoxically, cause “immune enhancement,” meaning they make it more likely, not less, that recipients will get a disease. That would be a disaster.
  • One candidate coronavirus vaccine Dr. Hotez invented 10 years ago in the wake of SARS, he said, had to be abandoned when it appeared to make mice more likely to die from pneumonia when they were experimentally infected with the virus.
  • Reach out to other nations
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Germany's coronavirus contact tracing offers a model for the U.S. - The Washington Post - 0 views

  • As the United Kingdom and the United States scramble to hire teams of contact tracers, local health authorities across Germany have used contact scouts such as Degidiben since they confirmed their first cases early this year.
  • Germany has experienced around 10 coronavirus deaths per 100,000 people
  • The United States has seen nearly three times as many. France, more than four times. Britain, more than 5½ times.
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  • As restrictions here are lifted, Chancellor Angela Merkel has singled out tracking infection chains as the key, above “all else.” Germany aims to have five contact tracers for every 25,000 people — or about 16,000 for its population of 83 million.
  • Privacy concerns — which run strong in Europe and particularly deep in Germany, with its not-so-distant memories of fascism and communism — have limited the potential of contact-tracing apps. So the tracing is largely a case of calling the recently diagnosed patient and asking his or her movements.
  • Germany’s trace-and-quarantine approach is by no means flawless. In about 65 percent of the cases here, health authorities have no idea how a person was infected. Asymptomatic carriers are no doubt falling through the cracks.
  • The whole conversation lasts just over 10 minutes. It’s a simple case, but that’s been normal since social distancing restrictions, health workers here say. Someone from the health department will call him daily to check in on his symptoms.
  • He contends that contact tracing and quarantines have been more important to containing the virus than the more widely lauded testing program.
  • “There are two things: the contact tracing and the quarantine,” Larscheid said. In Germany, the contacts of a positive coronavirus case are not generally tested unless they have symptoms.
  • “Testing is nice, but if you’re tested or not tested and are in quarantine, it makes no difference,” Larscheid said. Testing could also lull someone into a false sense of security, he said — a negative result might mean it’s just too early for an infection to register on a test.
  • Reinickendorf began to build its contact tracing team in March, as an outbreak in a kindergarten went beyond the capacity of the usual contingent of health officials. Workers were moved from parts of the local administration for which the outbreak had caused work to slow.
  • They say the numbers are distorted by isolated outbreaks in several nursing homes and a meatpacking plant. In Berlin, where there’s no requirement to wear a mask, there are only a few dozen new cases a day. Parks and markets have remained busy throughout the pandemic.
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Coronavirus fatality rate remains unknown as officials plan to reopen the economy - The... - 0 views

  • a fundamental question about the coronavirus pandemic remains unanswered: Just how deadly is this disease?
  • In Germany, fewer than three out of every 100 people with confirmed infections have died. In Italy the rate is almost five times higher, according to official figures.
  • Singapore, renowned for its careful testing, contact tracing and isolation of patients, saw only 10 deaths out of 4,427 cases through April 16. That yields a strikingly low case fatality rate of 0.2 percent, about twice the rate of seasonal influenza.
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  • No one knows exactly how many people died from influenza in 1918; estimates range from 15 million to 100 million globally. Historians estimate that the virus killed about 675,000 people in the United States across three waves of the pandemic
  • confirmed cases. But in this global crisis, both the numerator and the denominator are fuzzy.
  • the rising rate may reflect the disease’s gradual progression, combined with discoveries of additional deaths.
  • The disease is far more likely to cause severe outcomes in older people, with the oldest cohorts the most vulnerable. That said, in every age group — even 85-plus — most people who contract the disease will recover.
  • One scholarly estimate finds that the 1918-1920 pandemic killed 218 out of every 100,000 people living in the world at that time
  • In Spain, the death toll already stands at 41 out of 100,000 people; in Belgium the number is 45. In New York state, it is 63, and that number rises even higher if you consider the “probable” death toll in New York City.
  • So is the coronavirus as deadly? “This depends on how long this continues,”
  • The “virulence” of the virus — its ability to cause illness — has been steadily coming into focus.
  • But more than a month later, the WHO number has gone even higher: On April 16, the WHO showed a global fatality rate of 6.6 percent among confirmed cases.
  • Preliminary research indicates that the virus is not mutating significantly as it spreads, and so there is no evidence that some countries are dealing with a more virulent strain of SARS-CoV-2.
  • the median age of patients in Italy is 63 or 64 years; the median age of patients in Germany is 47. The mortality is much lower [in Germany] because they avoided having the older population affected.”
  • “If, in fact, the case fatality rate is higher than the 1918 flu, then this one has the potential to kill even more people,
  • “We saw it everyday. African Americans have three times the rate of chronic kidney disease that Caucasians have, and 25 percent higher heart disease. They’ve got higher rates of diabetes, hypertension and asthma,” Duggan said. “I fully expect that when people are hit hard and they are on a ventilator to breathe and their body needs to fight the infection, that people who already have compromised hearts or kidneys or lungs are that much more in jeopardy.”
  • Also critical is the nature, and robustness, of the national health system. For instance, Japan, where the current case fatality rate is 1.6 percent, and Singapore are reporting extremely high rates of hospitalization for coronavirus patients, at 80 percent and higher, figures that are unheard of in the United States. But this probably helps improve treatment and also reduces disease spread by isolating patients. The result is fewer deaths.
  • Several of the countries with low fatality rates — Germany, South Korea, Norway — have very high rates of coronavirus testing. This gave them a better look at the disease within their borders.
  • San Francisco General Hospital, noted that the hospital nearly tripled the capacity of its intensive care unit by adding doctors, nurses and technicians while the city adopted social distancing measures shortly ahead of New York.
  • “We were ready for a surge that never happened,” Balmes said. “They’re every bit as good as we are in intensive care in New York, but the system was overwhelmed. We did physical distancing just a few days earlier than New York, but it was a few days to the good.”
  • in a news conference that the global case fatality rate was 3.4 percent. That was treated as a revelation about the innate deadliness of the disease, but in fact was simply the WHO’s crude mortality ratio for confirmed covid-19 cases up to that point in time.
  • The other major factor in mortality is chronic disease. Most people hospitalized with severe cases of covid-19 have chronic health conditions such as diabetes, lung disease and heart disease. Where there is a high percentage of noncommunicable diseases like high blood pressure, the coronavirus will also be more deadly
  • A new study from researchers at Stanford, not yet peer-reviewed, looked for coronavirus antibodies in a sample population in Santa Clara County, Calif., and concluded that the actual infection rate in the county by early April was 50 to 85 times greater than the rate of confirmed cases.
  • “The story of this virus is turning out to be more about its contagiousness and less about its case fatality rate,” said David Rubin, director of PolicyLab at Children’s Hospital of Philadelphia and a University of Pennsylvania professor of pediatrics. “It’s less fatal than we thought, but it’s more contagious.”
  • Where extensive testing has been done, estimates for the case fatality rate are often below 1 percent, The Post has found, suggesting these countries are getting closer to a rate that takes into account all infections
  • In Iceland, which has tested over 10 percent of the population, vastly more than other countries, the fatality rate is just 0.5 percent.
  • Harvard epidemiologist Marc Lipsitch has written that he and most experts suspect the fatality rate is about 1 to 2 percent for symptomatic cases. A 1 percent fatality rate is 10 times the average fatality rate for seasonal flu.
  • “It’s probably about an order of magnitude higher for covid-19,” said Viboud, the NIH epidemiologist. “It’s more severe in terms of mortality than the pandemics we’ve seen since 1918.”
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Coronavirus Contact Tracing: Apple and Google Team Up to Enable Virus Tracking - The Ne... - 0 views

  • The technology giants said they would embed a feature in iPhones and Android devices to enable users to track infected people they’d come close to.
  • The technology giants said they were teaming up to release the tool within several months, building it into the operating systems of the billions of iPhones and Android devices around the world. That would enable the smartphones to constantly log other devices they come near, enabling what is known as “contact tracing” of the disease. People would opt in to use the tool and voluntarily report if they became infected.
  • underscores the seriousness of the health crisis and the power of the two companies whose software runs almost every smartphone in the world. Apple and Google said their joint effort came together in just the last two weeks.
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  • With the tool, people infected with the coronavirus would notify a public health app that they have it, which would then alert phones that had recently come into proximity with that person’s device. The companies would need to get public-health authorities to agree to link their app to the tool.
  • There are already third-party tools for contact tracing, including from public health authorities and the Massachusetts Institute of Technology. In March, the government of Singapore introduced a similar coronavirus contact-tracing app, called TraceTogether, that detects mobile phones that are nearby.
  • One challenge for third-party apps is that they must run constantly — 24 hours a day, seven days a week — to be effective. Google said some Android smartphone manufacturers shut down those applications to save battery life.
  • Apple and Google said their tool would also constantly run in the background if people opt to use it, logging nearby devices through the short-range wireless technology Bluetooth. But it would eat up less battery life and be more reliable than third-party apps, they said.
  • “This data could empower members of the general population to make informed decisions about their own health in terms of self-quarantining,” said Dr. Reid. “But it doesn’t replace the public health imperative that we scale up contact tracing in the public health departments” around the world.
  • Other phones will constantly check those servers for the broadcast beacons of devices they had come near in the past 14 days. If there is a match, those people will receive an alert that they had likely come into contact with an infected person.
  • Apple and Google said they were discussing how much information to include in those alerts with health officials, aiming to strike a balance between being helpful while also protecting the privacy of those who have the coronavirus.
  • Once someone reports his or her infection to a public-health app, the tool will send the phone’s so-called broadcast beacons, or anonymous identifiers connected to the device, to central computer servers.
  • Apple and Google said they would make the tool’s underlying technology available to third-party apps by mid-May and publicly release the tool “in the coming months.” The companies said the tool would not collect devices’ locations — it only tracked proximity to other devices — and would keep people anonymous in the central servers.
  • The European Commission, the executive of the 27-nation bloc, said on Wednesday that “a fragmented and uncoordinated approach risks hampering the effectiveness” of such apps.
  • “The danger is, as you roll out these voluntary solutions and they gain adoption, it’s more likely that they are going to become compulsory,” said Mr. Soltani, a former chief technologist for the Federal Trade Commission.
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Which States Have Coronavirus Travel Restrictions? - The Atlantic - 0 views

  • Hawaii has one of the strictest quarantine laws in the country.
  • The state’s geographic isolation has helped and hurt its efforts to control the virus. On one hand, the state would be completely unequipped to deal with a coronavirus surge. There are no states nearby from which to borrow doctors or ICU capacity. The island of Kauai has just 15 ventilators. On the other hand, everyone enters Hawaii through its airports, which makes enforcing a quarantine easier there than in almost every other state.
  • There’s no national database of quarantine noncompliance, but in U.S. states other than Hawaii, quarantine violations rarely result in fines or jail time—or, really, any consequences at all,
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  • Yet quarantine compliance is essential for the combination of testing, contact tracing, and isolation of sick people to work. Simply telling people they’ve been exposed and letting them loose on the nation’s Outback Steakhouses is not sufficient
  • Public-health departments are reluctant to seem like bad cops—or cops at all.
  • Hawaii created its quarantine law as a travel quarantine, stopping everyone at the airport. These types of quarantines are logistically easier to implement—they don’t require contact tracers—than medical quarantines, in which the state orders a certain individual to stay in isolation
  • Some other countries have imposed much tougher travel restrictions and quarantine policies. At one point, Greeks were required to text authorities to explain why they needed to go out. Norway quarantined its own citizens under threat of a fine or imprisonment. Most foreigners still can’t fly to Vietnam.
  • Keen believes that Hawaii residents are on such high alert because of long-ago pandemics that came to the islands and killed large percentages of the population
  • “Generations of stories you hear, from great-grandparents, grandparents, parents, that the pandemics nearly killed off Native Hawaiians,” she told me. “So there is a great fear here of outsiders coming in and bringing it with them.”
  • On the mainland, states cite a combination of COVID-19 denial, logistical hurdles, and funding and personnel shortages to explain why they haven’t been willing or able to enforce quarantines.
  • scofflaws: Some people stay inside for three or four days, then decide, “I’m bored with staying home,”
  • Even if a North Dakotan wants to do the right thing, she might not be able to without going hungry or losing her job. Grocery delivery isn’t available in parts of the large and rural state
  • Some states can’t quarantine people, because they have too many cases to trace
  • In fact, many COVID-exposed Americans who want to stay home and quarantine have an intractable problem: Their bosses won’t let them
  • The Families First Coronavirus Response Act granted paid leave to recover from COVID-19 to many Americans. But the law doesn’t cover everyone: Large companies aren’t included, and small companies can claim an exemption. Because of these exemptions, only 47 percent of private-sector workers have guaranteed access to coronavirus-related sick leave,
  • The U.S. is the only country out of 193 nations to exclude workers from sick-leave benefits based on the size of the company they work for, according to a recent UCLA study.
  • “We don’t really pay people to stay at home to quarantine,” Polly Price, a global-health professor at Emory University, says. But that’s exactly the problem: In a study in Israel, people were more likely to quarantine after exposure to COVID-19 if they were paid during their isolation.
  • Months into the pandemic, half of Americans didn’t know they might have the right to stay home with pay if they contracted the coronavirus.
  • even if they did, employers might have pressured them to come to work if they were no longer showing symptoms,
  • “After testing positive, employees are being scheduled and expected to work as long as they don’t show symptoms and [are] not placed in quarantine,” a worker at a Georgia taco restaurant complained in July. OSHA has formally inspected just 11 of the employers in these incidents. “Under the Trump administration, OSHA decided to do almost no enforcement,”
  • America’s laissez-faire federal pandemic response has, in effect, treated each state like its own country
  • When it comes time to isolate sick people, though, it becomes painfully clear that states aren’t countries. Wisconsin can’t stop Iowans from driving into it. North Dakota doesn’t have enough health workers to trace all of its infected citizens. The governor can’t help you when your employer is—legally—dragging you back into the office.
  • the reason Hawaii has been so ruthlessly effective at quarantine is that it in some ways still acts as its own country with its own border controls.
  • The state consistently has some of the lowest case numbers in the nation. As with so many other pandemic rules, Americans might not like quarantine, but it works.
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Demand Overwhelms Some U.S. Vaccine Registration Sites - 0 views

  • As states try to scale up vaccine rollouts that have been marred with confusion and errors, the online registration sites — operated by a welter of agencies and using a range of technologies — are crucial.
  • There are many, many more people who want to be vaccinated than there are opportunities to get the shot.
  • “The registration system worked as designed, but there is far greater demand than available supply at this time,”
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  • Beaumont Health, which operates several hospitals in the Metro Detroit area, had recently announced plans to offer residents 65 and older vaccinations, and about 25,000 people tried to gain access to the online portal simultaneously
  • Both of the vaccines being used across the country require patients to receive two doses spaced weeks apart, so the process of administering second shots to Americans has only just begun.
  • Even in states where online registration seemed to go well, some people were stuck with long waits.
  • At least 151,000 people in the United States have been fully vaccinated against Covid-19, according to a New York Times survey of all 50 states.
  • County officials had said they would have a limited number of slots for people 65 and older. The available slots were filled in 20 minutes,
  • Some states, including Florida, Louisiana and Texas, have already expanded who is eligible for the vaccine, even though many in the first priority group recommended by the Centers for Disease Control and Prevention — health care workers and residents of nursing homes and other long-term care facilities — have not yet received a shot.
  • about 6.7 million people had received a first dose of a vaccine. That falls far short of the goal federal officials set to give at least 20 million people their first shots before the end of 2020.
  • On Friday, the transition team for President-elect Joseph R. Biden Jr. announced a plan to accelerate vaccinations that includes reversing course and releasing nearly all available doses. That would provide more people with first doses but raise the risk that second doses would not be administered on time; however, ramped up vaccine production is expected to keep enough in the pipeline for timely second doses
  • The tally of fully vaccinated people is an undercount because some states did not provide that information.
  • Some states’ expansions have led to frantic and often futile efforts by older people to get vaccinated. After Florida opened up vaccinations to anyone 65 and older last month, the demand was so great that new online registration portals quickly overloaded and crashed, people spent hours on the phone trying to secure appointments and others waited overnight at scattered pop-up sites offering shots on a first-come first-served basis.
  • Vaccines alone will not be enough to get ahead of the virus: It will take years to inoculate enough people to limit its evolution. In the meantime, social distancing, mask-wearing and hand-washing — combined with aggressive testing, tracking and tracing — might buy some time and avert devastating spikes in hospitalizations and deaths along the way.
  • The rapid spread of the new variants is a reminder of the failings and missteps of major countries to contain the virus earlier.
  • Dr. Anthony S. Fauci, the top U.S. infectious disease expert, told performing arts professionals at a virtual conference on Saturday that he believed that theaters and other venues could reopen “some time in the fall of 2021,” depending on the vaccination rollout, and suggested that audiences might still be required to wear masks for some time.
  • A week after the first case of a highly contagious coronavirus variant first identified in Britain was found in New York, Gov. Andrew Cuomo announced Saturday that the state had found three additional cases.
  • The other case appears to be unrelated to those to Saratoga Springs and was traced back to a man in his 60s living in Massapequa, in Nassau County, Mr. Cuomo added. The man first tested positive for the coronavirus on Dec. 27.The travel history of those who tested positive for the variant in New York was unclear.
  • Pope Francis said in a soon-to-be-televised interview that he would be vaccinated against the coronavirus as early as next week, calling it a lifesaving, ethical obligation and the refusal to do so suicidal.
  • On Saturday, 1,035 people died of the coronavirus in Britain, a day after health officials reported the highest daily death toll since the pandemic started, with 1,325 deaths. Britain has been the worst-hit country in Europe, with nearly 80,000 deaths.
  • In a separate decision put in effect Thursday, face masks, long deemed ineffective by Swedish health officials, are now being recommended for use during rush hour on public transport, although they will not be mandatory.
  • On Friday, Britain suffered its deadliest daily toll since the beginning of the pandemic, with 1,325 deaths. On Saturday, the toll was 1,035 lives.— Elian Peltier
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This is how South Korea flattened its coronavirus curve - 0 views

  • This is how South Korea flattened its coronavirus curveSouth Korea's COVID-19 infection rates have been falling for two weeks thanks to a rigorous testing regime and clear public information.
  • Streetman, who works as a marketing manager at a gaming company in Seoul, received his negative results in less than 24 hours and is now one of more than 327,000 people out of the country's 51 million-strong population to have been tested for the coronavirus in South Korea since the country confirmed its first case Jan. 21.The U.S., which confirmed its first case the same day, is suffering from the repercussions of a weeks-late start in obtaining test kits
  • Here's what we can learn from South Korea.
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  • Early testing, detection, preventionNews that China had reported its first case of the coronavirus was enough reason for South Korean leaders and medical staff to brace themselves for the worst.
  • Acting fast was the most important decision South Korea made,"
  • Active collaboration among central and regional government officials and medical staff took place before cases began piling up, enabling South Korea's current testing capacity of 20,000 people a day at 633 sites, including drive-thru centers and even phone booths.
  • By early February, the first test had been approved
  • "Among Shincheonji members, there were many 20- and 30-year-olds who were infected. Many of them may have never even known they were carrying the virus and recovered easily while silently infecting those around them," Hwang said. "Early testing is why Korea hasn't reached its breaking point yet.
  • Under South Korea's single-payer health care system, getting tested costs $134. But with a doctor's referral or for those who've made contact with an infected person, testing is free. Even undocumented foreigners are urged to get tested and won't face threats due to their status.
  • South Korean leaders have amped up efficiency for overwhelmed hospitals by digitally monitoring lower-risk patients under quarantine, as well as keeping close tabs on visiting travelers who are required to enter their symptoms into an app.
  • Sites like Corona Map generate real-time updates about where current patients are located and inform proactive Koreans focused on protecting themselves.
  • That people are willing to forgo privacy rights and allow the publication of sensitive information underlines the willingness to pay the digital cost of state surveillance in the name of public safety,
  • 78.5 percent of respondents agreed that they would sacrifice the protection of their privacy rights to help prevent a national epidemic.
  • 97.6 percent responded that they at least sometimes wear a mask when they are outside, 63.6 percent of whom said they always wear one.
  • "Wearing masks or self-monitoring alone isn't foolproof to people in Korea, but taking part in these practices as a group is believed to have an impact,"
  • "This says that your individual choices may not have immediate benefit to you as an individual but will benefit the herd — that it doesn't work unless everybody is in the game."
  • Despite its apparently swift recovery from the coronavirus, South Korea may only be entering the beginning stages of what experts suspect may be a long ride ahead
  • bout 80 percent of COVID-19 cases can be categorized as mass infections. A call center in southwestern Seoul was at the center of a local outbreak this month that generated more than 156 infections. About 90 cases were traced to a Zumba class.
  • local infection clusters are emerging every day in churches, hospitals and other mundane spaces."
  • outh Korea has already started new testing on all arrivals from Europe, according to local news reports, preparing for a "second wave" of imported clusters. Even those who test negative are required to self-quarantine for 14 days
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Opinion: Whoever wins in November is going to have to solve the Covid-19 crisis - CNN - 0 views

  • Despite the deep divisions ravaging our country ahead of the presidential elections, many Americans are looking for answers to a common threat -- the coronavirus. As the daily number of cases and deaths have risen, we remain in the throes of a pandemic that has killed more than 225,000 of our fellow citizens and torpedoed our economy. Indeed, the US is averaging more than 68,000 new cases a day.
  • the next president will confront a dual challenge: managing the current pandemic and ensuring that the country and the world are better prepared when the next plague strikes -- as it inevitably will.
  • Nothing has undercut the US response to Covid-19 more than the failure to develop -- to this day -- a comprehensive nationwide system of testing and tracing that allows public health authorities to rapidly identify infected individuals and their contacts in order to isolate the sick from healthy populations.
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  • It is past time for the nation to make the investments we need to prevent, detect and respond quickly to emerging infectious diseases, like the coronavirus, before they sicken Americans and force catastrophic economic shutdowns.
  • The pandemic has taken a grievous toll on the elderly and nursing home residents specifically. It has also hit essential workers hard, and Black, Latino, Native and low-income Americans suffer disproportionately. As of the end of September, according to the Atlantic, Black Americans have died from Covid-19 at 2.3 times the rate of White Americans, comprising 21% of all US deaths from the disease
  • The success of public health measures like contact tracing, mask-wearing, and social distancing depends on individuals and communities trusting and adhering to advice from medical professionals and scientists, sometimes delivered by elected and other officials
  • That public trust must be earned and sustained.
  • Elected US officials, including the President, often have fallen short as communicators in this pandemic.
  • authorities are too often flying blind, uncertain of the trajectory of the disease, slow to identify hot spots and unable to stop the spread of the virus through targeted measures that do not require shutting down entire communities and economies.
  • US government authorities at all levels should target public health investments to increase the resilience of these communities, including universal paid sick leave in declared pandemics, accessible and free testing, and workplace protections and personal protective equipment for essential workers. Social justice and equity in our existing health care system is not just a moral mandate -- it is a matter of basic pandemic preparedness.
  • The smarter choice is to reform and strengthen the WHO as an essential cornerstone of global pandemic preparedness
  • The coronavirus demonstrates that an international framework for pandemic detection and response that relies so heavily on the transparency, judgment and discretion of individual national governments leaves too many opportunities for failure.
  • Alerts from that network should, in turn, notify national public health agencies and the WHO -- and trigger an international response.
  • Finally, the next president must resist the siren song of vaccine nationalism
  • So far, the US has chosen not to join COVAX, a groundbreaking consortium of more than 150 countries created not only to develop a vaccine but to ensure that when one emerges it is shared equitably, rather than hoarded by individual countries. We hope that the next president -- whoever he may be -- will reconsider this decision.
  • When it comes to pandemics, we all sink or swim together,
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Why Britain Failed Its Coronavirus Test - The Atlantic - 0 views

  • Britain has not been alone in its failure to prevent mass casualties—almost every country on the Continent suffered appalling losses—but one cannot avoid the grim reality spelled out in the numbers: If almost all countries failed, then Britain failed more than most.
  • The raw figures are grim. Britain has the worst overall COVID-19 death toll in Europe, with more than 46,000 dead according to official figures, while also suffering the Continent’s second-worst “excess death” tally per capita, more than double that in France and eight times higher than Germany’s
  • The British government as a whole made poorer decisions, based on poorer advice, founded on poorer evidence, supplied by poorer testing, with the inevitable consequence that it achieved poorer results than almost any of its peers. It failed in its preparation, its diagnosis, and its treatment.
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  • In the past two decades, the list of British calamities, policy misjudgments, and forecasting failures has been eye-watering: the disaster of Iraq, the botched Libyan intervention in 2011, the near miss of Scottish independence in 2014, the woeful handling of Britain’s divorce from the European Union from 2016 onward
  • What emerges is a picture of a country whose systemic weaknesses were exposed with appalling brutality, a country that believed it was stronger than it was, and that paid the price for failures that have built up for years
  • The most difficult question about all this is also the simplest: Why?
  • Like much of the Western world, Britain had prepared for an influenza pandemic, whereas places that were hit early—Hong Kong, South Korea, Singapore, Taiwan—had readied themselves for the type of respiratory illness that COVID-19 proved to be.
  • Britain’s pandemic story is not all bad. The NHS is almost universally seen as having risen to the challenge; the University of Oxford is leading the race to develop the first coronavirus vaccine for international distribution, backed with timely and significant government cash; new hospitals were built and treatments discovered with extraordinary speed; the welfare system did not collapse, despite the enormous pressure it suddenly faced; and a national economic safety net was rolled out quickly.
  • One influential U.K. government official told me that although individual mistakes always happen in a fast-moving crisis, and had clearly taken place in Britain’s response to COVID-19, it was impossible to escape the conclusion that Britain was simply not ready. As Ian Boyd, a professor and member of SAGE, put it: “The reality is, there has been a major systemic failure.”
  • “It’s obvious that the British state was not prepared for” the pandemic, this official told me. “But, even worse, many parts of the state thought they were prepared, which is significantly more dangerous.”
  • When the crisis came, too much of Britain’s core infrastructure simply failed, according to senior officials and experts involved in the pandemic response
  • The human immune system actually has two parts. There is, as Cummings correctly identifies, the adaptive part. But there is also an innate part, preprogrammed as the first line of defense against infectious disease. Humans need both. The same is true of a state and its government, said those I spoke with—many of whom were sympathetic to Cummings’s diagnosis. Without a functioning structure, the responsive antibodies of the government and its agencies cannot learn on the job. When the pandemic hit, both parts of Britain’s immune system were found wanting.
  • The consequences may be serious and long term, but the most immediately tragic effect was that creating space in hospitals appears to have been prioritized over shielding Britain’s elderly, many of whom were moved to care homes, part of what Britain calls the social-care sector, where the disease then spread. Some 25,000 patients were discharged into these care homes between March 17 and April 16, many without a requirement that they secure a negative coronavirus test beforehand.
  • There was a bit too much exceptionalism about how brilliant British science was at the start of this outbreak, which ended up with a blind spot about what was happening in Korea, Taiwan, Singapore, where we just weren’t looking closely enough, and they turned out to be the best in the world at tackling the coronavirus,” a former British cabinet minister told me.
  • The focus on influenza pandemics and the lack of a tracing system were compounded by a shortfall in testing capacity.
  • Johnson’s strategy throughout was one that his hero Winston Churchill raged against during the First World War, when he concluded that generals had been given too much power by politicians. In the Second World War, Churchill, by then prime minister and defense secretary, argued that “at the summit, true politics and strategy are one.” Johnson did not take this approach, succumbing—as his detractors would have it—to fatalistic management rather than bold leadership, empowering the generals rather than taking responsibility himself
  • “It was a mixture of poor advice and fatalism on behalf of the experts,” one former colleague of Johnson’s told me, “and complacency and boosterism on behalf of the PM.”
  • What it all adds up to, then, is a sobering reality: Institutional weaknesses of state capacity and advice were not corrected by political judgment, and political weaknesses were not corrected by institutional strength. The system was hardwired for a crisis that did not come, and could not adapt quickly enough to the one that did.
  • Britain’s NHS has come to represent the country itself, its sense of identity and what it stands for. Set up in 1948, it became known as the first universal health-care system of any major country in the world (although in reality New Zealand got there first). Its creation, three years after victory in the Second World War, was a high-water mark in the country’s power and prestige—a time when it was a global leader, an exception.
  • Every developed country in the world, apart from the United States, has a universal health-care system, many of which produce better results than the NHS.
  • When the pandemic hit, then, Britain was not the strong, successful, resilient country it imagined, but a poorly governed and fragile one. The truth is, Britain was sick before it caught the coronavirus.
  • In asking the country to rally to the NHS’s defense, Johnson was triggering its sense of self, its sense of pride and national unity—its sense of exceptionalism.
  • Before the coronavirus, the NHS was already under considerable financial pressure. Waiting times for appointments were rising, and the country had one of the lowest levels of spare intensive-care capacity in Europe. In 2017, Simon Stevens, the NHS’s chief executive, compared the situation to the time of the health sevice’s founding decades prior: an “economy in disarray, the end of empire, a nation negotiating its place in the world.”
  • Yet from its beginnings, the NHS has occupied a unique hold on British life. It is routinely among the most trusted institutions in the country. Its key tenet—that all Britons will have access to health care, free at the point of service—symbolizes an aspirational egalitarianism that, even as inequality has risen since the Margaret Thatcher era, remains at the core of British identity.
  • In effect, Britain was rigorously building capacity to help the NHS cope, but releasing potentially infected elderly, and vulnerable, patients in the process. By late June, more than 19,000 people had died in care homes from COVID-19. Separate excess-death data suggest that the figure may be considerably higher
  • Britain failed to foresee the dangers of such an extraordinary rush to create hospital capacity, a shift that was necessary only because of years of underfunding and decades of missed opportunities to bridge the divide between the NHS and retirement homes, which other countries, such as Germany, had found the political will to do.
  • Ultimately, the scandal is a consequence of a political culture that has proved unable to confront and address long-term problems, even when they are well known.
  • other health systems, such as Germany’s, which is better funded and decentralized, performed better than Britain’s. Those I spoke with who either are in Germany or know about Germany’s success told me there was an element of luck about the disparity with Britain. Germany had a greater industrial base to produce medical testing and personal protective equipment, and those who returned to Germany with the virus from abroad were often younger and healthier, meaning the initial strain on its health system was less.
  • However, this overlooks core structural issues—resulting from political choices in each country—that meant that Germany proved more resilient when the crisis came, whether because of the funding formula for its health system, which allows individuals more latitude to top up their coverage with private contributions, or its decentralized nature, which meant that separate regions and hospitals were better able to respond to local outbreaks and build their own testing network.
  • Also unlike Britain, which has ducked the problem of reforming elderly care, Germany created a system in 1995 that everyone pays into, avoids catastrophic costs, and has cross-party support.
  • A second, related revelation of the crisis—which also exposed the failure of the British state—is that underneath the apparent simplicity of the NHS’s single national model lies an engine of bewildering complexity, whose lines of responsibility, control, and accountability are unintelligible to voters and even to most politicians.
  • Britain, I was told, has found a way to be simultaneously overcentralized and weak at its center. The pandemic revealed the British state’s inability to manage the nation’s health:
  • Since at least the 1970s, growing inequality between comparatively rich southeast England (including London) and the rest of the country has spurred all parties to pledge to “rebalance the economy” and make it less reliant on the capital. Yet large parts remain poorer than the European average. According to official EU figures, Britain has five regions with a per capita gross domestic product of less than $25,000. France, Germany, Ireland, Austria, the Netherlands, Denmark, and Sweden have none
  • If Britain were part of the United States, it would be anywhere from the third- to the eighth-poorest state, depending on the measure.
  • Britain’s performance in this crisis has been so bad, it is damaging the country’s reputation, both at home and abroad.
  • Inside Downing Street, officials believe that the lessons of the pandemic apply far beyond the immediate confines of elderly care and coronavirus testing, taking in Britain’s long-term economic failures and general governance, as well as what they regard as its ineffective foreign policy and diplomacy.
  • the scale of the task itself is enormous. “We need a complete revamp of our government structure because it’s not fit for purpose anymore,” Boyd told me. “I just don’t know if we really understand our weakness.”
  • In practice, does Johnson have the confidence to match his diagnosis of Britain’s ills, given the timidity of his approach during the pandemic? The nagging worry among even Johnson’s supporters in Parliament is that although he may campaign as a Ronald Reagan, he might govern as a Silvio Berlusconi, failing to solve the structural problems he has identified.
  • This is not a story of pessimistic fatalism, of inevitable decline. Britain was able to partially reverse a previous slump in the 1980s, and Germany, seen as a European laggard in the ‘90s, is now the West’s obvious success story. One of the strengths of the Westminster parliamentary system is that it occasionally produces governments—like Johnson’s—with real power to effect change, should they try to enact it.
  • It has been overtaken by many of its rivals, whether in terms of health provision or economic resilience, but does not seem to realize it. And once the pandemic passes, the problems Britain faces will remain: how to sustain institutions so that they bind the country together, not pull it apart; how to remain prosperous in the 21st century’s globalized economy; how to promote its interests and values; how to pay for the ever-increasing costs of an aging population.
  • “The really important question,” Boyd said, “is whether the state, in its current form, is structurally capable of delivering on the big-picture items that are coming, whether pandemics or climate change or anything else.”
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Experts fear coronavirus will become a pandemic - The Washington Post - 0 views

  • There are outbreaks. There are epidemics. And there are pandemics, where epidemics become rampant in multiple countries and continents simultaneously. The novel coronavirus that causes the disease named covid-19 is on the verge of that third, globe-shaking stage
  • Amid an alarming surge in cases with no clear link to China, infectious disease experts believe the flulike illness may soon be impossible to contain
  • the language coming from the organization’s Geneva headquarters has turned more ominous in recent days as the challenge of containment grows more daunting.
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  • “The window of opportunity is still there, but the window of opportunity is narrowing,” WHO Director General Tedros Adhanom Ghebreyesus said on Friday. “We need to act quickly before it closes completely.”
  • At the beginning of any disease outbreak, public health experts painstakingly trace the contacts of every person who becomes sick. The experts build a family tree of possible illness, with branches that include anyone who might have shaken hands with, or been sneezed on by an infected person
  • with confirmed infections approaching 80,000 people, contact tracing on a case-by-case basis could soon be impractical.
  • “What we find is that this virus is going to be very difficult to contain,” said Jeffrey Shaman, an infectious disease researcher at Columbia University and co-author of the study posted Monday. “Personally, I don’t think we can do it.”
  • The word ‘pandemic’ invokes fear, but it describes how widespread an outbreak may be, not its deadliness.
  • “I think we should assume that this virus is very soon going to be spreading in communities here, if it isn’t already, and despite aggressive actions, we should be putting more efforts to mitigate impacts,”
  • The virus would be easier to contain if people who are contagious were obviously so, as was the case with SARS, which started an outbreak that burned itself out in 2003. But the new virus appears to spread among people who in some cases are not noticeably sick.
  • among the more than 600 passengers from the Diamond Princess cruise ship who have tested positive, about half had no obvious symptoms.
  • If the coronavirus becomes a true pandemic, a large proportion of the human population — a third, a half, two-thirds even — could become infected
  • Harvard epidemiologist Marc Lipsitch estimates that 40 to 70 percent of the human population could potentially be infected by the virus if it becomes pandemic. Not all of those people would get sick
  • The novel coronavirus may be particularly suited for stealth community transmission since its symptoms can be indistinguishable from those of a cold or flu, and testing capabilities are still being ramped up.
  • Experts estimate it takes about a week for the number of people infected in a given community to double. Based on that, it would likely take several weeks for a new infection cluster to be picked up by a local health department
  • By mid-March, he estimated, officials should know if there is community transmission and a true pandemic.
  • “I want to be clear that we are not seeing community spread here in the United States yet,” she said Friday. “But it’s very possible, even likely, that may eventually happen.”
  • “If a large number of countries are unsuccessful in preventing sustained multi-generation transmissions, then we could witness the next pandemic.”
  • A pandemic is a line in the sand, and every expert has a slightly different definition for when an outbreak crosses it. Generally, it means that there are self-sustaining lines of infection in multiple countries and continents — where the family tree of possible illness begins to encompass the entire population.
  • I think we’re not in as dire straits as we might be, and that’s because everyone is pulling together internationally.”
  • Public health experts are devising strategies on how to conserve N95 respirators, specialized masks that are in a limited supply amid surging demand.
  • “Extrapolating from some of the numbers we’ve seen on the impact to the health care system in China, it means we’ll have to surge fast.”
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Taiwan Covid: How they went 200 days without a locally transmitted case - CNN - 0 views

  • As much of the world struggles to contain new waves of the Covid-19 pandemic, Taiwan just marked its 200th consecutive day without a locally transmitted case of the disease.
  • Taipei's response to the coronavirus pandemic has been one of the world's most effective. The island of 23 million people last reported a locally transmitted case on April 12, which was Easter Sunday. As of Thursday, it had confirmed 553 cases -- only 55 of which were local transmissions. Seven deaths have been recorded.
  • Easter was an important milestone in the United States because President Donald Trump had said a month earlier he wanted the country "opened up and just raring to go" by the holiday.
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  • On Friday, those figures had passed 45 million cases and more than 1.1 million deaths, according to Johns Hopkins University.
  • Taiwan's landmark achievement comes in a week when France and Germany are enacting new lockdowns and the United States identified a record 88,000-plus cases in a day. The state of Florida, which has a similar population size to Taiwan, with approximately 21 million people, identified 4,188 cases on Wednesday alone.
  • Taiwan's response focused on speed. Taiwanese authorities began screening passengers on direct flights from Wuhan, where the virus was first identified, on December 31, 2019 -- back when the virus was mostly the subject of rumors and limited reporting.
  • Taiwan confirmed its first reported case of the novel coronavirus on January 21 and then banned Wuhan residents from traveling to the island. All passengers arriving from mainland China, Hong Kong and Macao were required to undergo screening.
  • All this happened before Wuhan itself went into lockdown on January 23.
  • By March, Taiwan banned all foreign nationals from entering the island, apart from diplomats, residents and those with special entry visas.
  • One is geography -- Taiwan is an island, so it's easier for officials to control entry and exit through its borders.
  • Taiwan also had experience on its side. After suffering through the deadly outbreak of severe acute respiratory syndrome (SARS) in 2003, Taiwan worked to build up its capacity to deal with a pandemic
  • Authorities activated the island's Central Epidemic Command Center, which was set up in the wake of SARS, to coordinate between different ministries. The government also ramped up face mask and protective equipment production to make sure there would be a steady supply of PPE.
  • The government also invested in mass testing and quick and effective contact tracing.
  • "Very careful contact tracing, and very stringent quarantines of close contacts are the best way to contain Covid-19," he said.
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