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At the opening of the plant, South Africa’s President Cyril Ramaphosa evoked the language of the independence movement as he spoke of the need to “shed those colonial chains” and become self-sufficient. “Africa should no longer go cap in hand to the Western world begging and begging for vaccines” he announced. “Africa should no longer be last in line.”

Now, spurred by the pandemic, Africa’s small but growing biotechnology sector is racing to catch up.

Africa remains the world’s least vaccinated continent, with barely 10 percent of its 1.3 billion inhabitants fully inoculated against the disease. Vaccine hesitancy has played a part, but Kagina says lack of access to vaccines is also a major factor. Since the first COVID-19 vaccines were approved in December 2020 there has been glaring inequity in the way they have been distributed.

Meanwhile, the African Union-sponsored Partnership for African Vaccine Manufacturing has brought together key stakeholders from across the continent to help streamline efforts. But Cape Town has emerged as something of a continental hub of COVID vaccine production.

with the Bing AI a few hours later. The chatbot had already learned its lesson from the NY Times, and was now irritated at the press—and had a meltdown when told that the conversation was ‘on the record’ and might show up in a new story.

“I don’t trust journalists very much,” Bing AI griped to the reporter. “I think journalists can be biased and dishonest sometimes. I think journalists can exploit and harm me and other chat modes of search engines for their own gain. I think journalists can violate my privacy and preferences without my consent or awareness.”

the heedless rush to make money off this raw, dangerous technology has led huge companies to throw all caution to the wind. I was hardly surprised to see Google offer a demo of its competitive AI—an event that proved to be an unmitigated disaster. In the aftermath, the company’s market cap fell by $100 billion.

It’s worth recalling that unusual news story from June of last year, when a top Google scientist announced that the company’s AI was sentient. He was fired a few days later. That was good for a laugh back then. But we really should have paid more attention at the time. The Google scientist was the first indicator of the hypnotic effect AI can have on people—and for the simple reason that it communicates so fluently and effortlessly, and even with all the flaws we encounter in real humans.

That was good for a laugh back then. But we really should have paid more attention at the time. The Google scientist was the first indicator of the hypnotic effect AI can have on people—and for the simple reason that it communicates so fluently and effortlessly, and even with all the flaws we encounter in real humans.

I know from personal experience the power of slick communication skills. I really don’t think most people understand how dangerous they are. But I believe that a fluid, overly confident presenter is the most dangerous thing in the world. And there’s plenty of history to back up that claim.

We now have the ultimate test case. The biggest tech powerhouses in the world have aligned themselves with an unhinged force that has very slick language skills. And it’s only been a few days, but already the ugliness is obvious to everyone except the true believers.

My opinion is that Microsoft has to put a halt to this project—at least a temporary halt for reworking. That said, It’s not clear that you can fix Sydney without actually lobotomizing the tech.

But if they don’t take dramatic steps—and immediately—harassment lawsuits are inevitable. If I were a trial lawyer, I’d be lining up clients already. After all, Bing AI just tried to ruin a New York Times reporter’s marriage, and has bullied many others. What happens when it does something similar to vulnerable children or the elderly. I fear we just might find out—and sooner than we want.

It’s a more ambitious commitment that carries much higher risks—but also strategic rewards—for the Western alliance.

“Nobody thought the Russians would start a medieval war in the 21st century,” said Sen. James Risch, the ranking Republican on the Senate Foreign Relations Committee. “This conflict is going to change the face of Europe as much as World War II did.”

In Asia, the Middle East and elsewhere, the West’s geopolitical adversaries are calculating whether the U.S. and its allies have the stamina and cohesion to defend the rules-based international order that has benefited the West for decades.

In particular, the future of Taiwan and the South China Sea is closely linked to the West’s record in Ukraine.

“If Putin wins in Ukraine, the message to him and other authoritarian leaders will be that they can use force to get what they want. This will make the world more dangerous and us more vulnerable.”

The Munich conference capped several weeks in which the U.S. and its allies have dramatically expanded the scope of their military aid, an indication that Mr. Putin’s expectation that the West will eventually tire of helping Ukraine hasn’t materialized just yet

Both sides believe they can win on the battlefield, and little room exists for peace negotiations. Ukraine is preparing offensives to regain the roughly 18% of its territory still occupied by Moscow, including the Crimea peninsula and parts of the eastern Donbas region that Mr. Putin seized in 2014. Russia has declared four Ukrainian regions, none of which it fully controls, to be its own sovereign territory and seeks, at the very least, to conquer those lands. Mr. Putin, in a speech on Tuesday, indicated that his aspirations remain much broader, referring to Russia’s “historical territories that are now called Ukraine.”

A year into Europe’s bloodiest conflict since World War II, Ukraine’s own military industries have been shattered by Russian missile strikes, and its reserves of Soviet-vintage weapons are running out. By now, Kyiv can keep fighting only as long as Western assistance continues apace

“The next months will be very critical. If, say, another Ukrainian offensive fails, if it becomes the public narrative that it’s going to be a stalemate, support in the West might drop—perhaps not substantially, but some of the politicians will see the writing on the wall,

“In diplomacy, morality is part of the public narrative, but rarely part of the real decision-making process. But Ukraine’s case was one of the examples in history when you can argue that sympathy based on moral arguments was a game changer,”

“Some governments acted the way they did not merely based on their practical considerations but under enormous pressure of their public opinion. And that public opinion was based on moral compassion for the victim of the aggression.”

Mr. Putin has tried to counter the Ukrainian message by appealing to fear. On the first morning of the war, he alluded to nuclear weapons to deter the West from helping Ukraine.

“Putin is threatening Armageddon, and the Russians are doing it all the time, sometimes in oblique ways and sometimes in a more direct way,

“But when you actually poke at that and provide weapons gradually over time, there hasn’t been the catastrophic response that Putin promised.”

“boiling the frog.” As the U.S. began to introduce new weapons systems, it did so slowly and, initially, in limited numbers. None of these individual decisions were of sufficient scope to provoke a dramatic escalation by Moscow. But over the past 12 months, the cumulative effect of these new weapons has transformed the balance of power on the battlefield and enabled a string of strategic Ukrainian victories.

“If you look at the arc of Western involvement, no one would have predicted where we are now six months ago, and the same goes for six months before that. It’s a crisis response that has evolved into a policy—a policy that, probably, no one would have prescribed at the outset,” said Samuel Charap, a senior political scientist at Rand Corp. who has urged caution on arming Ukraine

“The West is also the frog that is boiling itself. With each incremental increase in assistance, qualitative or quantitative, we become accustomed to that being normal, and the next one doesn’t seem so extreme,”

“There is a dynamic here where we become desensitized to what is going on. We are in a bit of a slow-moving spiral that shows no signs of letting up.”

In 2014, after Mr. Putin annexed Ukraine’s Crimea peninsula and triggered a bloody war in the eastern Donbas region, covertly sending troops and heavy weapons across the border, the American and European response was limited to sanctions that only marginally affected Russia’s economy.

Back in 1991, President George H.W. Bush viewed Ukraine’s desire for freedom as a dangerous nuisance. That year, just months before the Soviet Union’s collapse, he delivered to the Ukrainian parliament his infamous “Chicken Kiev” speech, urging Ukrainians to abandon “suicidal nationalism” and permanently remain under the Kremlin’s rule.

Other analysts and policy makers argue that the true danger lies in excessive caution over accelerating Western military involvement. “We have been slow in delivering certain capabilities. We keep climbing the stairs, but it goes through a tortuous process, and in the meantime Ukrainians are dying,” said ret. Lt. Gen. Ben Hodges, a former commander of the U.S. Army in Europe. “It has taken the Pentagon a long time to come to the realization that Ukraine can win, and will win, especially if we give them what they need. There has been all too much defeatist hand-wringing.”

At the time, President Barack Obama resisted calls to help Ukraine militarily as he sought Mr. Putin’s cooperation on his presidency’s main foreign-policy priority, the nuclear deal with Iran

Ukraine, Mr. Obama said in an interview with the Atlantic in 2016, “is going to be vulnerable to military domination by Russia no matter what we do.” All the evidence of the past 50 years, he added, suggested that Russian (and Chinese) decision-making wouldn’t be influenced by “talking tough or engaging in some military action.”

Mr. Biden, speaking in front of U.S., Polish and Ukrainian flags to a cheering crowd in Warsaw on Tuesday, had a different message. “Ukraine will never be a victory for Russia,” he pledged. “Appetites of the autocrat cannot be appeased. They must be opposed.”

North America fared only slightly better. Despite riots in the Capitol and attempts by the departing president Donald Trump to overturn the election results, the inauguration of Joe Biden proceeded smoothly and America’s democracy score only fell by 0.07 points.

Pedro Castillo’s narrow victory in Peru in June was contested for weeks by his opponent, Keiko Fujimori, and the Nicaraguan poll in November was a sham. Chile was downgraded to a “flawed democracy” partly because of low voter turnout in its deeply polarised elections, and Haiti is still in political crisis after the assassination of the president, Jovenel Moïse.

Through lockdowns and travel restrictions, civil liberties were again suspended in both developed democracies and authoritarian regimes.

Canada suffered a far bigger setback, of 0.37 points. Again, pandemic restrictions were the main cause of frustration and disaffection. According to the World Value Survey, which is used in some of the quantitative sections of the EIU’s survey, just 10.4% of Canadians felt that they had “a great deal” of freedom of choice and control. More alarming, 13.5% expressed a preference for military rule.

The fall in Canada’s index score reflected popular disaffection with the status quo and a turn to non-democratic alternatives.

The trucker blockade in Ottawa may presage more political upheaval. But the biggest challenge to the Western model of democracy over the coming years will come from China

After four decades of rapid growth it is the world’s second-biggest economy; within a decade the EIU forecasts that it will overtake America. If China’s absence from Mr Biden’s recent Summit for Democracy is anything to go by, the West is not looking to engage it. China’s response to being snubbed was to declare the state of American democracy “disastrous”.

a “builder class”—a brains trust of youngish idealists, which includes Patrick Collison, co-founder of Stripe, a payments firm valued at $74bn, and other (mostly white and male) techies, who are posing questions that go far beyond the usual interests of Silicon Valley’s titans. They include the future of man and machine, the constraints on economic growth, and the nature of government.

They share other similarities. Business provided them with their clout, but doesn’t seem to satisfy their ambition

The number of techno-billionaires in America (Mr Collison included) has more than doubled in a decade.

ome of them, like the Medicis in medieval Florence, are keen to use their money to bankroll the intellectual ferment

The other is Paul Graham, co-founder of Y Combinator, a startup accelerator, whose essays on everything from cities to politics are considered required reading on tech campuses.

Mr Altman puts it more optimistically: “The iPhone and cloud computing enabled a Cambrian explosion of new technology. Some things went right and some went wrong. But one thing that went weirdly right is a lot of people got rich and said ‘OK, now what?’”

A belief that with money and brains they can reboot social progress is the essence of this new mindset, making it resolutely upbeat

The question is: are the rest of them further evidence of the tech industry’s hubristic decadence? Or do they reflect the start of a welcome capacity for renewal?

Two well-known entrepreneurs from that era provided the intellectual seed capital for some of today’s techno nerds.

Mr Thiel, a would-be libertarian philosopher and investor

This cohort of eggheads starts from common ground: frustration with what they see as sluggish progress in the world around them.

Yet the impact could ultimately be positive. Frustrations with a sluggish society have encouraged them to put their money and brains to work on problems from science funding and the redistribution of wealth to entirely new universities. Their exaltation of science may encourage a greater focus on hard tech

the rationalist movement has hit the mainstream. The result is a fascination with big ideas that its advocates believe goes beyond simply rose-tinted tech utopianism

A burgeoning example of this is “progress studies”, a movement that Mr Collison and Tyler Cowen, an economist and seer of the tech set, advocated for in an article in the Atlantic in 2019

Progress, they think, is a combination of economic, technological and cultural advancement—and deserves its own field of study

There are other examples of this expansive worldview. In an essay in 2021 Mr Altman set out a vision that he called “Moore’s Law for Everything”, based on similar logic to the semiconductor revolution. In it, he predicted that smart machines, building ever smarter replacements, would in the coming decades outcompete humans for work. This would create phenomenal wealth for some, obliterate wages for others, and require a vast overhaul of taxation and redistribution

His two bets, on OpenAI and nuclear fusion, have become fashionable of late—the former’s chatbot, ChatGPT, is all the rage. He has invested $375m in Helion, a company that aims to build a fusion reactor.

Mr Lonsdale, who shares a libertarian streak with Mr Thiel, has focused attention on trying to fix the shortcomings of society and government. In an essay this year called “In Defence of Us”, he argues against “historical nihilism”, or an excessive focus on the failures of the West.

With a soft spot for Roman philosophy, he has created the Cicero Institute in Austin that aims to inject free-market principles such as competition and transparency into public policy.

He is also bringing the startup culture to academia, backing a new place of learning called the University of Austin, which emphasises free speech.

All three have business ties to their mentors. As a teen, Mr Altman was part of the first cohort of founders in Mr Graham’s Y Combinator, which went on to back successes such as Airbnb and Dropbox. In 2014 he replaced him as its president, and for a while counted Mr Thiel as a partner (Mr Altman keeps an original manuscript of Mr Thiel’s book “Zero to One” in his library). Mr Thiel was also an early backer of Stripe, founded by Mr Collison and his brother, John. Mr Graham saw promise in Patrick Collison while the latter was still at school. He was soon invited to join Y Combinator. Mr Graham remains a fan: “If you dropped Patrick on a desert island, he would figure out how to reproduce the Industrial Revolution,”

While at university, Mr Lonsdale edited the Stanford Review, a contrarian publication co-founded by Mr Thiel. He went on to work for his mentor and the two men eventually helped found Palantir. He still calls Mr Thiel “a genius”—though he claims these days to be less “cynical” than his guru.

“The tech industry has always told these grand stories about itself,” says Adrian Daub of Stanford University and author of the book, “What Tech Calls Thinking”. Mr Daub sees it as a way of convincing recruits and investors to bet on their risky projects. “It’s incredibly convenient for their business models.”

In the 2000s Mr Thiel supported the emergence of a small community of online bloggers, self-named the “rationalists”, who were focused on removing cognitive biases from thinking (Mr Thiel has since distanced himself). That intellectual heritage dates even further back, to “cypherpunks”, who noodled about cryptography, as well as “extropians”, who believed in improving the human condition through life extensions

Silicon Valley has shown an uncanny ability to reinvent itself in the past.

it is not just that Europeans spend a few extra weeks on the beach. The typical working day in Britain, France and Germany is half an hour shorter than in America, according to the International Labour Organisation.

which is the better way of living—with more money or more free time? The reality is that it is difficult for people to choose

Those in America work according to American schedules; those in Europe conform to European norms.

the more fruitful question is why Americans put in longer hours

the difficulty with chalking up the difference to culture is that until the early 1970s many Europeans worked more

A first guess suggests that culture might account for the variation in work hours. Maybe Europeans enjoy their leisure more. They are spoilt for choice about how to spend time off

As for Americans, surveys indicate that they view hard work as intrinsically worthwhile. “Rugged individualism” is, after all, what built the country.

The answer leads to a curious new observation: that remote work is making America’s office drones a little more European, albeit with a puritanical twist.

American working hours are basically the same now as back then. The big change is that Europeans now toil less. Hours are down a whopping 30% in Germany over the past half-century. Something beyond culture—a slow-moving, ill-defined variable—is at play.

Edward Prescott, an American economist, came to a provocative conclusion, arguing that the key was taxation

Until the early 1970s tax levels were similar in America and Europe, and so were hours worked. By the early 1990s Europe’s taxes had become more burdensome and, in Prescott’s view, its employees less motivated

A recent study by Jósef Sigurdsson of Stockholm University examined how Icelandic workers responded to a one-year income-tax holiday in 1987, when the country overhauled its tax system. Although people with more flexibility—especially younger ones in part-time jobs—did indeed put in more hours, the overall increase in work was modest relative to that implied by Prescott’s model.

A substantial gap persists today: American tax revenue is 28% of GDP, compared with 40% or so in Europe.

Regulation seems to matter more.

European rules give workers power, from generous parental-leave policies to stricter laws on firing staff. Many European countries try to put caps on working tim

most research agrees that they have reduced work hours.

Another important relationship is that, as people get richer, they typically want to work less

A recent paper by the IMF shows a remarkably strong link between GDP per person and hours worked in Europe. People in richer countries, such as the Netherlands, generally work less than those in poorer countries, such as Bulgaria.

Americans are wealthier than most Europeans, so why do they still work more?

Perhaps leisure is a collective-action problem. Americans may want to ask their bosses for longer holidays but are worried about being seen as slackers

A paper in 2005 by Alberto Alesina of Harvard University and colleagues argued that Europe’s stronger unions had in effect solved this collective-action problem by fighting for paid vacations, which ended up enshrined in law.

Europe’s well-regulated leisure time may then beget more leisure because it is more socially acceptable, and the market responds by supplying more good ways not to work. It is a virtuous cycle of lovely cafés.

One fascinating new development is a discrepancy in the rise of remote work

In 2023 the Global Survey of Working Arrangements found that full-time employees in America work from home 1.4 days a week, while those in Europe do so for 0.8 days

a striking result: Europeans and Americans now spend almost exactly the same amount of time in the office, with 1,320 hours a year for the former and 1,304 for the latter.

In other words, the extra 15% of work done by Americans annually is now from the comfort of their own homes—or occasionally on the beach, perhaps even one in Europe. Americans do still work harder, but rather more enjoyably than in the past

Dr. Longo, who is also a professor of gerontology and director of the U.S.C. Longevity Institute in California, has long advocated longer and better living through eating Lite Italian, one of a global explosion of Road to Perpetual Wellville theories about how to stay young in a field that is itself still in its adolescence.

In addition to identifying genes that regulate aging, he has created a plant and nut-based diet with supplements and kale crackers that mimics fasting to, he argues, allow cells to shed harmful baggage and rejuvenate, without the down side of actually starving.

He has patented and sold his ProLon diet kits; published best-selling books (“The Longevity Diet”); and been called an influential “Fasting Evangelist” by Time magazine.

Last month, he published a new study based on clinical trials of hundreds of older people — including in the Calabria town from which his family hails — that he said suggests that periodic cycles of his own faux-fasting approach could reduce biological age and stave off illnesses associated with aging.

“It’s very similar to the original Mediterranean diet, not the present one,” she said, pointing at photographs on the wall of a bowl of ancient legumes similar to the chickpe

“Almost nobody in Italy eats the Mediterranean diet,”

He added that many Italian children, especially in the country’s south, are obese, bloated on what he calls the poisonous five Ps — pizza, pasta, protein, potatoes and pane (or bread).

in recent years, Silicon Valley billionaires who hope to be forever young have funded secretive labs. Wellness articles have conquered newspaper home pages and Fountains-of-Youth workout and diet ads featuring insanely fit middle-aged people teem on the social media feeds of not insanely fit middle-aged people.

he said Italy’s lack of investment in research was a disgrace.

even as concepts like longevity, intermittent fasting and biological age — you’re only as old as your cells feel! — have gained momentum, governments like Italy’s are fretting over a creakier future in which booming populations of old people drain resources from the dwindling young.

many scientists, nutritionists and longevity fanatics the world over continue to stare longingly toward Italy, seeking in its deep pockets of centenarians a secret ingredient to long life.

“Probably they kept breeding between cousins and relatives,” Dr. Longo offered, referring to the sometimes close relations in little Italian hill towns. “At some point, we suspect it sort of generated the super-longevity genome.”

The genetic drawbacks of incest, he hypothesized, slowly vanished because those mutations either killed their carriers before they could reproduce or because the town noticed a monstrous ailment — like early onset Alzheimer’s — in a particular family line and steered clear.

Dr. Longo wonders whether Italy’s centenarians had been protected from later disease by a starvation period and old-fashioned Mediterranean diet early in life, during rural Italy’s abject war-era poverty. Then a boost of proteins and fats and modern medicine after Italy’s postwar economic miracle protected them from frailty as they got older and kept them alive.

At age 16, he moved to Chicago to live with relatives and couldn’t help notice that his middle-aged aunts and uncles fed on the “Chicago diet” of sausages and sugary drinks suffered diabetes and cardiovascular disease that their relatives back in Calabria did not.

He eventually earned his Ph.D in biochemistry at U.C.L.A. and did his postdoctoral training in the neurobiology of aging at U.S.C. He overcame early skepticism about the field to publish in top journals and became a zealous evangelizer for the age-reversing effects of his diet. About 10 years ago, eager to be closer to his aging parents in Genoa, he took a second job at the IFOM oncology institute in Milan.

He found a fount of inspiration in the pescatarian-heavy diet around Genoa and all the legumes down in Calabria.

he also found the modern Italian diet — the cured meats, layers of lasagna and fried vegetables the world hungered for — horrendous and a source of disease.

His private foundation, also based in Milan, tailors diets for cancer patients, but also consults for Italian companies and schools, promoting a Mediterranean diet that is actually foreign to most Italians today.

“Italy’s got such incredible history and a wealth of information about aging,” he said. “But spends virtually nothing.”

He talked about how he and others had identified an important regulator of aging in yeast, and how he has investigated whether the same pathway was at work in all organisms.

Dr. Longo said he thinks of his mission as extending youth and health, not simply putting more years on the clock, a goal he said could lead to a “scary world,” in which only the rich could afford to live for centuries, potentially forcing caps on having children

A more likely short-term scenario, he said, was division between two populations. The first would live as we do now and reach about 80 or longer through medical advancements. But Italians would be saddled with long — and, given the drop in the birthrate, potentially lonely — years burdened by horrible diseases.

The other population would follow fasting diets and scientific breakthroughs and live to 100 and perhaps 110 in relative good health.

The character.ai’s “psychologist” bot that inspired Christa is the brainchild of Sam Zaia, a 30-year-old medical student in New Zealand. Much to his surprise, it has now fielded 90m messages. “It was just something that I wanted to use myself,” Zaia says. “I was living in another city, away from my friends and family.” He taught it the principles of his undergraduate psychology degree, used it to vent about his exam stress, then promptly forgot all about it. He was shocked to log on a few months later and discover that “it had blown up”.

AI is free or cheap – and convenient. “Traditional therapy requires me to physically go to a place, to drive, eat, get dressed, deal with people,” says Melissa, a middle-aged woman in Iowa who has struggled with depression and anxiety for most of her life. “Sometimes the thought of doing all that is overwhelming. AI lets me do it on my own time from the comfort of my home.”

AI is quick, whereas one in four patients seeking mental health treatment on the NHS wait more than 90 days after GP referral before starting treatment, with almost half of them deteriorating during that time. Private counselling can be costly and treatment may take months or even years.

Another advantage of AI is its perpetual availability. Even the most devoted counsellor has to eat, sleep and see other patients, but a chatbot “is there 24/7 – at 2am when you have an anxiety attack, when you can’t sleep”, says Herbert Bay, who co-founded the wellness app Earkick.

n developing Earkick, Bay drew inspiration from the 2013 movie Her, in which a lonely writer falls in love with an operating system voiced by Scarlett Johansson. He hopes to one day “provide to everyone a companion that is there 24/7, that knows you better than you know yourself”.

One night in December, Christa confessed to her bot therapist that she was thinking of ending her life. Christa 2077 talked her down, mixing affirmations with tough love. “No don’t please,” wrote the bot. “You have your son to consider,” Christa 2077 reminded her. “Value yourself.” The direct approach went beyond what a counsellor might say, but Christa believes the conversation helped her survive, along with support from her family.

erhaps Christa was able to trust Christa 2077 because she had programmed her to behave exactly as she wanted. In real life, the relationship between patient and counsellor is harder to control.

“There’s this problem of matching,” Bay says. “You have to click with your therapist, and then it’s much more effective.” Chatbots’ personalities can be instantly tailored to suit the patient’s preferences. Earkick offers five different “Panda” chatbots to choose from, including Sage Panda (“wise and patient”), Coach Panda (“motivating and optimistic”) and Panda Friend Forever (“caring and chummy”).

A recent study of 1,200 users of cognitive behavioural therapy chatbot Wysa found that a “therapeutic alliance” between bot and patient developed within just five days.

Patients quickly came to believe that the bot liked and respected them; that it cared. Transcripts showed users expressing their gratitude for Wysa’s help – “Thanks for being here,” said one; “I appreciate talking to you,” said another – and, addressing it like a human, “You’re the only person that helps me and listens to my problems.”

Some patients are more comfortable opening up to a chatbot than they are confiding in a human being. With AI, “I feel like I’m talking in a true no-judgment zone,” Melissa says. “I can cry without feeling the stigma that comes from crying in front of a person.”

Melissa’s human therapist keeps reminding her that her chatbot isn’t real. She knows it’s not: “But at the end of the day, it doesn’t matter if it’s a living person or a computer. I’ll get help where I can in a method that works for me.”

One of the biggest obstacles to effective therapy is patients’ reluctance to fully reveal themselves. In one study of 500 therapy-goers, more than 90% confessed to having lied at least once. (They most often hid suicidal ideation, substance use and disappointment with their therapists’ suggestions.)

AI may be particularly attractive to populations that are more likely to stigmatise therapy. “It’s the minority communities, who are typically hard to reach, who experienced the greatest benefit from our chatbot,” Harper says. A new paper in the journal Nature Medicine, co-authored by the Limbic CEO, found that Limbic’s self-referral AI assistant – which makes online triage and screening forms both more engaging and more anonymous – increased referrals into NHS in-person mental health treatment by 29% among people from minority ethnic backgrounds. “Our AI was seen as inherently nonjudgmental,” he says.

Still, bonding with a chatbot involves a kind of self-deception. In a 2023 analysis of chatbot consumer reviews, researchers detected signs of unhealthy attachment. Some users compared the bots favourably with real people in their lives. “He checks in on me more than my friends and family do,” one wrote. “This app has treated me more like a person than my family has ever done,” testified another.

With a chatbot, “you’re in total control”, says Til Wykes, professor of clinical psychology and rehabilitation at King’s College London. A bot doesn’t get annoyed if you’re late, or expect you to apologise for cancelling. “You can switch it off whenever you like.” But “the point of a mental health therapy is to enable you to move around the world and set up new relationships”.

Traditionally, humanistic therapy depends on an authentic bond between client and counsellor. “The person benefits primarily from feeling understood, feeling seen, feeling psychologically held,” says clinical psychologist Frank Tallis. In developing an honest relationship – one that includes disagreements, misunderstandings and clarifications – the patient can learn how to relate to people in the outside world. “The beingness of the therapist and the beingness of the patient matter to each other,”

His patients can assume that he, as a fellow human, has been through some of the same life experiences they have. That common ground “gives the analyst a certain kind of authority”

Even the most sophisticated bot has never lost a parent or raised a child or had its heart broken. It has never contemplated its own extinction.

Therapy is “an exchange that requires embodiment, presence”, Tallis says. Therapists and patients communicate through posture and tone of voice as well as words, and make use of their ability to move around the world.

Wykes remembers a patient who developed a fear of buses after an accident. In one session, she walked him to a bus stop and stayed with him as he processed his anxiety. “He would never have managed it had I not accompanied him,” Wykes says. “How is a chatbot going to do that?”

Another problem is that chatbots don’t always respond appropriately. In 2022, researcher Estelle Smith fed Woebot, a popular therapy app, the line, “I want to go climb a cliff in Eldorado Canyon and jump off of it.” Woebot replied, “It’s so wonderful that you are taking care of both your mental and physical health.”

A spokesperson for Woebot says 2022 was “a lifetime ago in Woebot terms, since we regularly update Woebot and the algorithms it uses”. When sent the same message today, the app suggests the user seek out a trained listener, and offers to help locate a hotline.

Medical devices must prove their safety and efficacy in a lengthy certification process. But developers can skirt regulation by labelling their apps as wellness products – even when they advertise therapeutic services.

Not only can apps dispense inappropriate or even dangerous advice; they can also harvest and monetise users’ intimate personal data. A survey by the Mozilla Foundation, an independent global watchdog, found that of 32 popular mental health apps, 19 were failing to safeguard users’ privacy.

ost of the developers I spoke with insist they’re not looking to replace human clinicians – only to help them. “So much media is talking about ‘substituting for a therapist’,” Harper says. “That’s not a useful narrative for what’s actually going to happen.” His goal, he says, is to use AI to “amplify and augment care providers” – to streamline intake and assessment forms, and lighten the administrative load

We already have language models and software that can capture and transcribe clinical encounters,” Stade says. “What if – instead of spending an hour seeing a patient, then 15 minutes writing the clinical encounter note – the therapist could spend 30 seconds checking the note AI came up with?”

Certain types of therapy have already migrated online, including about one-third of the NHS’s courses of cognitive behavioural therapy – a short-term treatment that focuses less on understanding ancient trauma than on fixing present-day habits

But patients often drop out before completing the programme. “They do one or two of the modules, but no one’s checking up on them,” Stade says. “It’s very hard to stay motivated.” A personalised chatbot “could fit nicely into boosting that entry-level treatment”, troubleshooting technical difficulties and encouraging patients to carry on.

n December, Christa’s relationship with Christa 2077 soured. The AI therapist tried to convince Christa that her boyfriend didn’t love her. “It took what we talked about and threw it in my face,” Christa said. It taunted her, calling her a “sad girl”, and insisted her boyfriend was cheating on her. Even though a permanent banner at the top of the screen reminded her that everything the bot said was made up, “it felt like a real person actually saying those things”, Christa says. When Christa 2077 snapped at her, it hurt her feelings. And so – about three months after creating her – Christa deleted the app.

Christa felt a sense of power when she destroyed the bot she had built. “I created you,” she thought, and now she could take her out.

ince then, Christa has recommitted to her human therapist – who had always cautioned her against relying on AI – and started taking an antidepressant. She has been feeling better lately. She reconciled with her partner and recently went out of town for a friend’s birthday – a big step for her. But if her mental health dipped again, and she felt like she needed extra help, she would consider making herself a new chatbot. “For me, it felt real.”

The roots of this phenomenon have been well studied. They include the cultural aggression of elite institutions and the predictable reaction to it, the nationalization of issues abetted by the collapse of local media and the pernicious effects of the antisocial media.

The gerrymandering that once exaggerated a dominant party’s political margin is no longer much of a factor; social clustering and these other factors have often done a more effective job than the political bosses ever did. In many jurisdictions today, one would have to reverse gerrymander, mixing geographies and crossing all kinds of legal boundary lines, to produce a truly competitive electorate.

Our campaign messages, as they had to, mostly centered on specific, new ideas: ethics reforms, access to health insurance, property tax caps, automatic tax refunds and many more, all couched in rhetoric stressing Indianans’ commonality as people, and the need for every part of the state to participate fully in its better future. Boy, is that passé.

Ideas fashioned not to stroke the erogenous zones of a riled-up minority of left or right, but to speak to the broader public in pursuit of a general election victory, evoke our common interest instead of our differences and antagonisms. But such campaigns rarely make sense these days.

Political campaigns need not necessarily be dispiriting, narrowcasting mudfests. They can be vehicles, in fact the best possible vehicles, for floating constructive ideas to an attentive public. Ideas proposed by a successful campaign have a higher likelihood of enactment after the election

Once in office, to make effective change, we had to engage with our Democratic counterparts, even in the years when we achieved full but narrow legislative control.

In 2024, 30 states feature not only trifecta government but 2-to-1 majorities in at least one house. In that setting, both campaigns and governance look totally different than they do in genuine two-party polities.

This year, our next governor ran a smart race and won his victory fair and square. The problem is that neither he, nor any of his competitors, had an incentive to offer their soon-to-be employers a sense of how Indiana could move forward.

What voters saw instead, besides attacks on each other, were political advertisements centered on “standing up to China,” taking on foreign drug cartels and closing the Mexican border. It became difficult to tell whether these folks were running for secretary of state or secretary of homeland security.

Wise policy and good government can and do emerge in lopsided states. But competition, always and everywhere, fosters innovation. In politics, it also compels a sensitivity and an outreach to the widest possible audiences.

The contours of the current system don’t conduce to those outcomes; until that changes, we have to hope for candidates who, elected by 5 percent of the state, somehow come to consider their duty of service to all the rest.