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These past studies of exercise and neurogenesis understandably have focused on distance running. Lab rodents know how to run. But whether other forms of exercise likewise prompt increases in neurogenesis has been unknown and is an issue of increasing interest

new study, which was published this month in the Journal of Physiology, researchers at the University of Jyvaskyla in Finland and other institutions gathered a large group of adult male rats. The researchers injected the rats with a substance that marks new brain cells and then set groups of them to an array of different workouts, with one group remaining sedentary to serve as controls.

They found very different levels of neurogenesis, depending on how each animal had exercised. Those rats that had jogged on wheels showed robust levels of neurogenesis. Their hippocampal tissue teemed with new neurons, far more than in the brains of the sedentary animals. The greater the distance that a runner had covered during the experiment, the more new cells its brain now contained. There were far fewer new neurons in the brains of the animals that had completed high-intensity interval training. They showed somewhat higher amounts than in the sedentary animals but far less than in the distance runners. And the weight-training rats, although they were much stronger at the end of the experiment than they had been at the start, showed no discernible augmentation of neurogenesis. Their hippocampal tissue looked just like that of the animals that had not exercised at all.

“sustained aerobic exercise might be most beneficial for brain health also in humans.”

Just why distance running was so much more potent at promoting neurogenesis than the other workouts is not clear, although Dr. Nokia and her colleagues speculate that distance running stimulates the release of a particular substance in the brain known as brain-derived neurotrophic factor that is known to regulate neurogenesis. The more miles an animal runs, the more B.D.N.F. it produces. Weight training, on the other hand, while extremely beneficial for muscular health, has previously been shown to have little effect on the body’s levels of B.D.N.F.

As for high-intensity interval training, its potential brain benefits may be undercut by its very intensity, Dr. Nokia said. It is, by intent, much more physiologically draining and stressful than moderate running, and “stress tends to decrease adult hippocampal neurogenesis,” she said.

These results do not mean, however, that only running and similar moderate endurance workouts strengthen the brain, Dr. Nokia said. Those activities do seem to prompt the most neurogenesis in the hippocampus. But weight training and high-intensity intervals probably lead to different types of changes elsewhere in the brain. They might, for instance, encourage the creation of additional blood vessels or new connections between brain cells or between different parts of the brain.

They were right about control but wrong about the controllers. Our Internet handlers, not government, are using operant conditioning to modify our behavior today.

we now know how to design cue, activity, and reward systems to more effectively leverage our brain chemistry and program human behavior.

The beauty of the Internet is that by combining big data, behavioral targeting, wearable and mobile devices, and GPS, application developers can design more effective operant conditioning environments and keep us in virtual Skinner boxes as long as we have a smart phone in our pockets.

Operant conditioning techniques will and are currently being used to program the behavior of susceptible Internet users -- young men who play MMORPG (Massively Multiplayer Online Role-Playing Games) for forty hours a week, women who commit hours to social networks, shoppers seeking the thrill of a deal, and poker players.

As smart devices become integrated into our lives, retailers who will know where we are standing in stores and fast food restaurants and bars will find ways to provide us with cues to trigger behaviors.

The real question is how many hundreds of millions of us will become susceptible to what I believe will prove to be history's most potent marketing techniques.

The technical term that might apply here is ‘sleep paralysis,’ a subtype of parasomnia, or sleep disturbance. Beyond the inability to move, these periods of wakeful paralysis are often accompanied with vivid multisensory hallucinations.

Effectively, imagery from your dreams can actually intrude into your waking reality.

Records of incidents attributable to sleep paralysis can actually be found throughout history and across cultures with records dating back at least as far as 400 BC.

For comparison’s sake, consider this account by Jon Loudner, who gave ‘evidence’ during the infamous Salem Witch Trials in 1692:

Witchcraft is a less popular explanation for contemporary sufferers, but even today, the precise physiological mechanisms that result in sleep paralysis are still not entirely understood.

a circuit breaker; it effectively blocks your brain’s motor planning signals from becoming motor action signals

However, our brains are highly complex systems, and, as such, are prone to the occasional glitch.

Researchers have shown that sleep paralysis experiences can be induced in laboratory participants when they are repeatedly woken from deep sleep.

Given their highly subjective nature, dreams are notoriously difficult to study scientifically.

In fact, the connection between video games and dreams is one of the better documented areas of research on the subjective experiences of dreamers. 

This evidence has been used to support the idea that sleeping might serve to ‘consolidate’ memories from our waking life - consolidation is term that refers to the process of reinforcing and strengthening newly created memories.

Various experiments have demonstrated that people who are given memory-based tasks will perform better if they’re given the opportunity to sleep after learning

In both rats and humans, the hippocampus is the part of the brain, which among other functions, is strongly associated with the way we form memories of physical spaces.

As the rats slept, the cells in the hippocampus would light up with activity. And not just any activity – the patterns of activations that occurred while the rats slept corresponded with the pattern associated with the correct maze runs

One caveat is that none of this work proves a direct causal link between dreaming and memories: dreaming itself might not cause the memories to be reinforced, but could simply be a kind of side-effect of the consolidation process. 

Because cells are connected in a network, brain activity produces a synchronised pulse of electrical activity, which is called a “brain wave”.

Brainwaves are detected using a technique known as electroencephalography (EEG),

The pattern of activity is then recorded and interpreted using computer software.

The electrical nature of the brain allows not only for sending of signals, but also for the receiving of electrical pulses

A TMS device creates a magnetic field over the scalp, which then causes an electrical current in the brain.

The connection was reinforced by giving both rats a reward when the receiver rat performed the task correctly.

By combining EEG and TMS, scientists have transmitted the thought of moving a hand from one person to a separate individual, who actually moved their hand.

including EEG, the Internet and TMS – the team of researchers was able to transmit a thought all the way from India to France.

Words were first coded into binary notation

Now that these BBI technologies are becoming a reality, they have a huge potential to impact the way we interact with other humans. And maybe even the way we communicate with animals through direct transmission of thought.

Such technologies have obvious ethical and legal implications, however. So it is important to note that the success of BBIs depends upon the conscious coupling of the subjects.

Contemporary science has refined the old “fight or flight” concept — the idea that those are the two hard-wired options when in mortal danger — to the updated “freeze, flee, fight.”

Why do we freeze? It’s part of a predatory defense system that is wired to keep the organism alive. Not only do we do it, but so do other mammals and other vertebrates. Even invertebrates — like flies — freeze. If you are freezing, you are less likely to be detected if the predator is far away, and if the predator is close by, you can postpone the attack (movement by the prey is a trigger for attack)

The freezing reaction is accompanied by a hormonal surge that helps mobilize your energy and focus your attention. While the hormonal and other physiological responses that accompany freezing are there for good reason, in highly stressful situations the secretions can be excessive and create impediments to making informed choices.

Sometimes freezing is brief and sometimes it persists. This can reflect the particular situation you are in, but also your individual predisposition. Some people naturally have the ability to think through a stressful situation, or to even be motivated by it, and will more readily run, hide or fight as required.

we have created a version of this predicament using rats. The animals have been trained, through trial and error, to “know” how to escape in a certain dangerous situation. But when they are actually placed in the dangerous situation, some rats simply cannot execute the response — they stay frozen. If, however, we artificially shut down a key subregion of the amygdala in these rats, they are able to overcome the built-in impulse to freeze and use their “knowledge” about what to do.

shown that if people cognitively reappraise a situation, it can dampen their amygdala activity. This dampening may open the way for conceptually based actions, like “run, hide, fight,” to replace freezing and other hard-wired impulses.

How to encourage this kind of cognitive reappraisal? Perhaps we could harness the power of social media to conduct a kind of collective cultural training in which we learn to reappraise the freezing that occurs in dangerous situations. In most of us, freezing will occur no matter what. It’s just a matter of how long it will last.

We seem driven (so to speak) to transform cars, conveyances that show us the world, into machines that also see the world for

There is evidence that one’s cognitive map can deteriorate. A widely reported study published in 2006 demonstrated that the brains of London taxi drivers have larger than average amounts of gray matter in the area responsible for complex spatial relations. Brain scans of retired taxi drivers suggested that the volume of gray matter in those areas also decreases when that part of the brain is no longer being used as frequently. “I think it’s possible that if you went to someone doing a lot of active navigation, but just relying on GPS,” Hugo Spiers, one of the authors of the taxi study, hypothesized to me, “you’d actually get a reduction in that area.”

A consequence is a possible diminution of our “cognitive map,” a term introduced in 1948 by the psychologist Edward Tolman of the University of California, Berkeley. In a groundbreaking paper, Dr. Tolman analyzed several laboratory experiments involving rats and mazes. He argued that rats had the ability to develop not only cognitive “strip maps” — simple conceptions of the spatial relationship between two points — but also more comprehensive cognitive maps that encompassed the entire maze.

Could society’s embrace of GPS be eroding our cognitive maps? For Julia Frankenstein, a psychologist at the University of Freiburg’s Center for Cognitive Science, the danger of GPS is that “we are not forced to remember or process the information — as it is permanently ‘at hand,’ we need not think or decide for ourselves.” She has written that we “see the way from A to Z, but we don’t see the landmarks along the way.” In this sense, “developing a cognitive map from this reduced information is a bit like trying to get an entire musical piece from a few notes.” GPS abets a strip-map level of orientation with the world.

We seem driven (so to speak) to transform cars, conveyances that show us the world, into machines that also see the world for us.

For Dr. Tolman, the cognitive map was a fluid metaphor with myriad applications. He identified with his rats. Like them, a scientist runs the maze, turning strip maps into comprehensive maps — increasingly accurate models of the “great God-given maze which is our human world,” as he put it. The countless examples of “displaced aggression” he saw in that maze — “the poor Southern whites, who take it out on the Negros,” “we psychologists who criticize all other departments,” “Americans who criticize the Russians and the Russians who criticize us” — were all, to some degree, examples of strip-map comprehension, a blinkered view that failed to comprehend the big picture. “What in the name of Heaven and Psychology can we do about it?” he wrote. “My only answer is to preach again the virtues of reason — of, that is, broad cognitive maps.”

hippocampus,

Electrodes implanted in these patients' brains help their surgeons precisely identify the seizure foci and also provide valuable information on the brain's inner workings, Lega says.

new treatments to combat memory loss from conditions such as traumatic brain injury or Alzheimer's disease.

In addition, while rats are actively exploring an environment, place cells are further organized into "mini-sequences" that represent a virtual sweep of locations ahead of the rat. These radar-like sweeps happen roughly 8-10 times per second and are thought to be a brain mechanism for predicting immediately upcoming events or outcomes.

it was unclear how the hippocampus was able to produce such sequences.

hocolate milk

However, taking a closer look at the data, the researchers found something new: As the rats moved through these spaces, their neurons not only exhibited forward, predictive mini-sequences, but also backward, retrospective mini-sequences. The forward and backward sequences alternated with each other, each taking only a few dozen milliseconds to complete.

"In the past few decades, there's been an explosion in new findings about memory,"

"What happens when you put anti-wrinkle cream on an elephant?" (See National Geographic's elephant pictures.)

African elephants are also more wrinkled than their forest-dwelling Asian relatives.

Elephants aren't the only creased creatures that benefit from wrinkles. Take the naked mole rat, whose saggy skin makes moving around easier.

India presents a striking example of the limitations of pure economics. From 2003 to 2011, the world’s largest democracy was growing at a phenomenal rate, exceeding 9 percent each year between 2005 and 2008. Even after 2011, it kept up a reasonable rate of growth. However, since 2018, the economy seems to be spinning into a crisis, with growth declining to 4.5 percent, consumption in India’s vast rural sector declining at rates not seen since the late 1960s, and the overall unemployment rate at a 45-year high. The 2018 Accidental Deaths and Suicides in India Report, recently released by the National Crime Records Bureau, highlights a stark mood of despair: Since 2017, there has been a noticeable rise in the relative share of suicides by daily wage earners. They are among the poorest people in the economic ladder, thereby suggesting a rise in poverty.

A recent Harvard Business Review paper shows that if a company’s workers have a sense of belonging, they improve their job performance by 56 percent, with a 50 percent drop in churn and a 75 percent reduction in sick days. For a 10,000-person company, this would result in annual savings of more than $52 million. Extrapolate this to a nation, and you get a sense of why nations where large segments feel excluded do poorly.

The philosopher Immanuel Kant (1724–1804) argued in his Critique of Pure Reason that the human mind knows objects in innate, a priori ways. Kant claimed that humans, from birth, must experience all objects as being successive (time) and juxtaposed (space). His list of inborn categories describes predicates that the mind can attribute to any object in general. Arthur Schopenhauer (1788–1860) agreed with Kant, but reduced the number of innate categories to one—causality—which presupposes the others.

Modern nativism is most associated with the work of Jerry Fodor (1935–2017), Noam Chomsky (b. 1928), and Steven Pinker (b. 1954), who argue that humans from birth have certain cognitive modules (specialised genetically inherited psychological abilities) that allow them to learn and acquire certain skills, such as language.

For example, children demonstrate a facility for acquiring spoken language but require intensive training to learn to read and write. This poverty of the stimulus observation became a principal component of Chomsky's argument for a "language organ"—a genetically inherited neurological module that confers a somewhat universal understanding of syntax that all neurologically healthy humans are born with, which is fine-tuned by an individual's experience with their native language

In The Blank Slate (2002), Pinker similarly cites the linguistic capabilities of children, relative to the amount of direct instruction they receive, as evidence that humans have an inborn facility for speech acquisition (but not for literacy acquisition).

A number of other theorists[1][2][3] have disagreed with these claims. Instead, they have outlined alternative theories of how modularization might emerge over the course of development, as a result of a system gradually refining and fine-tuning its responses to environmental stimuli.[4]

Many empiricists are now also trying to apply modern learning models and techniques to the question of language acquisition, with marked success.[20] Similarity-based generalization marks another avenue of recent research, which suggests that children may be able to rapidly learn how to use new words by generalizing about the usage of similar words that they already know (see also the distributional hypothesis).[14][21][22][23]

The term universal grammar (or UG) is used for the purported innate biological properties of the human brain, whatever exactly they turn out to be, that are responsible for children's successful acquisition of a native language during the first few years of life. The person most strongly associated with the hypothesising of UG is Noam Chomsky, although the idea of Universal Grammar has clear historical antecedents at least as far back as the 1300s, in the form of the Speculative Grammar of Thomas of Erfurt.

This evidence is all the more impressive when one considers that most children do not receive reliable corrections for grammatical errors.[9] Indeed, even children who for medical reasons cannot produce speech, and therefore have no possibility of producing an error in the first place, have been found to master both the lexicon and the grammar of their community's language perfectly.[10] The fact that children succeed at language acquisition even when their linguistic input is severely impoverished, as it is when no corrective feedback is available, is related to the argument from the poverty of the stimulus, and is another claim for a central role of UG in child language acquisition.

Researchers at Blue Brain discovered a network of about fifty neurons which they believed were building blocks of more complex knowledge but contained basic innate knowledge that could be combined in different more complex ways to give way to acquired knowledge, like memory.[11

experience, the tests would bring about very different characteristics for each rat. However, the rats all displayed similar characteristics which suggest that their neuronal circuits must have been established previously to their experiences. The Blue Brain Project research suggests that some of the "building blocks" of knowledge are genetic and present at birth.[11]

modern nativist theory makes little in the way of specific falsifiable and testable predictions, and has been compared by some empiricists to a pseudoscience or nefarious brand of "psychological creationism". As influential psychologist Henry L. Roediger III remarked that "Chomsky was and is a rationalist; he had no uses for experimental analyses or data of any sort that pertained to language, and even experimental psycholinguistics was and is of little interest to him".[13]

, Chomsky's poverty of the stimulus argument is controversial within linguistics.[14][15][16][17][18][19]

Neither the five-year-old nor the adults in the community can easily articulate the principles of the grammar they are following. Experimental evidence shows that infants come equipped with presuppositions that allow them to acquire the rules of their language.[6]

Paul Griffiths, in "What is Innateness?", argues that innateness is too confusing a concept to be fruitfully employed as it confuses "empirically dissociated" concepts. In a previous paper, Griffiths argued that innateness specifically confuses these three distinct biological concepts: developmental fixity, species nature, and intended outcome. Developmental fixity refers to how insensitive a trait is to environmental input, species nature reflects what it is to be an organism of a certain kind, and the intended outcome is how an organism is meant to develop.[24]

students didn't want to be anywhere near the computers

pencil-and-paper creativity quiz, the so-called Remote Associates Test, which asks people to identify word associations that aren't immediately obvious. Four days into the trip, they took the test again

45 percent improvement.

hardly scientific.

took the test four days into the wilderness did 50 percent better than those who were still immersed in modern lif

Outward Bound is notoriously strict about bringing artifacts of modern life into the wilderness.

Half of the 56 hikers took the test before going backpacking in the wilderness, and the other half took the RAT test on the fourth day of their trip. The groups went into the wild in Alaska, Colorado, Maine and Washington.

researchers had already taken the test once.

exposure to nature over a number of days, which has been shown in other studies to improve thinking

exercise

abandoning electronic devices

constant texting and checking in on Facebook are not making us think more clearly.

If so, would people choose to take it? Could criminals be given the option, as an alternative to prison, of a drug-releasing implant that would make them less likely to harm others?

many argued that we could never be justified in depriving someone of his free will, no matter how gruesome the violence that would thereby be prevented. No doubt any proposal to develop a morality pill would encounter the same objection.

But if our brain’s chemistry does affect our moral behavior, the question of whether that balance is set in a natural way or by medical intervention will make no difference in how freely we act. If there are already biochemical differences between us that can be used to predict how ethically we will act, then either such differences are compatible with free will, or they are evidence that at least as far as some of our ethical actions are concerned, none of us have ever had free will anyway.

According to the psychologist Stéphane Bouchard, who studies phobia at the University of Quebec, about a third of phobias are indeed set off by direct exposure to frightening encounters, such as a dog bite. Roughly another third are culturally suggested: a classic example being the increase in shark and water phobias after the movie “Jaws.” With that final third, Mr. Bouchard told me, shrugging, “we just have no clue.”Let me zero in on that final third.“I have a fear of honeycomb shapes,” a woman once wrote to me when I solicited examples of phobias for my research. “I can’t look at something like a beehive. The other day, I saw a box of honeycomb-shaped pasta at the grocery store and it really creeped me out.”

We are not simple creatures, we human beings, and we know it; yet we still insist on imposing simple explanations upon our emotional conduct. “They’re just freaking dandelions, Mom,” my son tells me. It’s just a garter snake. They’re merely peas. How in the world  can you be so idiotically afraid of clowns?There are wider implications here for our civic and political discourse. Certain people may be neurologically prone to anxiety, true, but fear is also circumstantial. The current economic climate is extremely anxiety-provoking, and research has shown that people can tolerate uncertainty for only so long. At some point, the neurotically wired begin to prefer negative certitudes  — or compartmentalized threats  — to ambiguity.

Oddly, this act of transmuting anxiety into fear does possess a kind of logic. Anxiety has been described as fear in search of a cause, and there’s little question that fear is more actionable. Instead of being paralyzed by a sense of directionless menace, as would be the case with a generalized anxiety disorder where danger is everywhere and nowhere, the phobic can pour all dread into one vessel, and then swiftly run away.In other words, phobia can be a form of compartmentalization.

A fear of flying, for instance, can relate to acrophobia (fear of heights), or to claustrophobia, or it can be a stand-in for a much more threatening prospect that dare not be confronted at any cost, such as the death of a parent. You’re avoiding grief, and the next thing you know you would rather be trapped in an elevator with bees than board an airplane. The airplane is departing for another world but no, that’s too obvious.

Of all the manifestations of anxiety, specific phobias are by far the most idiosyncratic. About 6 percent of Americans have an acute fear of animals like rats and birds. But after that, the sources of terror are myriad.

f we cannot tolerate uncertainty, then it might be reasonable to expect an increase in phobic behaviors:   xenophobia, Islamophobia, Obamafear, a terror of newts. These aren’t stances that can be dealt with by counterargument.  They can be quelled only by exposure, by a reminder that the threat is symbolic, a stand-in. Let’s invite the enemy we  fear to dine, then, and rescue ourselves  from irrational conflict.

These clashing perspectives are reflected in the perennial conflict between two dieting dicta: 1) avoid temptation and 2) don't make yourself feel deprived. There is some truth to both views. 

The mating and cohabitation produced the exact same effects [as TSA],” said Bruce Cushing, a behavioral neuroscientist at the University of Akron who was not involved in the study. “That is really powerful.”

a growing number of scientists are using autonomous robots to interrogate animal behavior and cognition. Researchers have designed robots to behave like ants, cockroaches, rodents, chickens, and more, then deployed their bots in the lab or in the environment to see how similarly they behave to their flesh-and-blood counterparts.

robots give behavioral biologists the freedom to explore the mind of an animal in ways that would not be possible with living subjects, says University of Sheffield researcher James Marshall, who in March helped launch a 3-year collaborative project to build a flying robot controlled by a computer-run simulation of the entire honeybee brain.

“I really think there is a lot to be discovered by doing the engineering side along with the science.”

Not only did the bots move around the space like the rat pups did, they aggregated in remarkably similar ways to the real animals.3 Then Schank realized that there was a bug in his program. The robots weren’t following his predetermined rules; they were moving randomly.

Animal experiments are still needed to advance neuroscience.” But, he adds, robots may prove to be an indispensable new ethological tool for focusing the scope of research. “If you can have good physical models,” Prescott says, “then you can reduce the number of experiments and only do the ones that answer really important questions.”

animal-mimicking robots is not easy, however, particularly when knowledge of the system’s biology is lacking.

However, when the researchers also gave the robots a sense of flow, and programmed them to assume that odors come from upstream, the bots much more closely mimicked real lobster behavior. “That was a demonstration that the animals’ brains were multimodal—that they were using chemical information and flow information,” says Grasso, who has since worked on robotic models of octopus arms and crayfish.

some sense, the use of robotics in animal-behavior research is not that new. Since the inception of the field of ethology, researchers have been using simple physical models of animals—“dummies”—to examine the social behavior of real animals, and biologists began animating their dummies as soon as technology would allow. “The fundamental problem when you’re studying an interaction between two individuals is that it’s a two-way interaction—you’ve got two players whose behaviors are both variable,”

building a robot that animals will accept as one of their own is complicated, to say the least.

handful of other researchers have also successfully integrated robots with live animals—including fish, ducks, and chickens. There are several notable benefits to intermixing robots and animals; first and foremost, control. “One of the problems when studying behavior is that, of course, it’s very difficult to have control of animals, and so it’s hard for us to interpret fully how they interact with each other

Like all animal brains, human brains are not general-purpose universal learning machines, but, instead, are intricately structured suites of instincts optimized for the environments in which they evolved. To harness our brains, we want to let the brain’s brilliant mechanisms run as intended—i.e., not to be twisted. Rather, the strategy is to twist Y into a shape that the brain does know how to process.

there is a very good reason to be optimistic that the next stage of human will come via the form of adaptive harnessing, rather than direct technological enhancement: It has already happened. We have already been transformed via harnessing beyond what we once were. We’re already Human 2.0, not the Human 1.0, or Homo sapiens, that natural selection made us. We Human 2.0’s have, among many powers, three that are central to who we take ourselves to be today: writing, speech, and music (the latter perhaps being the pinnacle of the arts). Yet these three capabilities, despite having all the hallmarks of design, were not a result of natural selection, nor were they the result of genetic engineering or cybernetic enhancement to our brains. Instead, and as I argue in both The Vision Revolution and my forthcoming Harnessed, these are powers we acquired by virtue of harnessing, or neuronal recycling.

Although the step from Human 1.0 to 2.0 was via cultural selection, not via explicit human designers, does the transformation to Human 3.0 need to be entirely due to a process like cultural evolution, or might we have any hope of purposely guiding our transformation? When considering our future, that’s probably the most relevant question we should be asking ourselves.

One of my reasons for optimism is that nature-harnessing technologies (like writing, speech, and music) must mimic fundamental ecological features in nature, and that is a much easier task for scientists to tackle than emulating the exhorbitantly complex mechanisms of the brain