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Sleep is tied to many positive health outcomes according to a constant stream of medical research, much of which recommends more than seven hours a night. My goal was to sleep eight hours each night, and for the first two weeks of the month I tried and failed. I didn't manage it once. It started stressing me out.Wake up, people: You're fooling yourself about sleep, study says I did get more sleep than I would have otherwise because I prioritized getting to bed earlier. But between work, training for a marathon, kids' bedtimes and evening plans, my life was not conducive to that schedule. But since I'm making up the rules (and you make up yours) I gave up on sleep.

Research ties nature exposure to both longevity and happiness, so I made it a goal to commune with nature every day. This could include a run through a park, stopping to hug a tree (which I did at least once), or watching a convoy of ants cross a sidewalk.

Another super-habit for mental and physical health, I made an effort to incorporate meditation in some form -- whether it was 10 breaths, 30 minutes, guided, formal, mantra-led, what have you -- every day.

To complement March's switch-up, my plan for June was the same split: 8 hours of sleep at night and active listening with the kids. I didn't think I could pull a straight fortnight of great sleep, so my aim was for 15 nights of sleep and 15 days of not doing something else while listening.

At CNN, I sit near a constant pile of sweets. And that combined with my weakness for them equals a snacking problem. So in July, my goal was to make fresh fruit my standard snack of choice and eat at least one piece or serving a day. And more water -- at least a pint before coffee in the morning.

In August I attempted to not stay seated for more than 30 minutes during waking hours. Recent research has associated a number of poor health conditions with a sedentary lifestyle. And while no one can definitively say how much sitting is bad for us, moving every 30 minutes has emerged as a good guideline.

My commitment in September was 15 minutes of some form of creative writing each day, almost entirely in a writer's notebook that I've had since college. It's full of random dialogue, lists and story plots, and I used to write in it often but not so much in recent years.

Read a novel. That was it. Given that I mainly read non-fiction, this idea seemed rather novel (sorry).

My intention was to make a daily gesture of gratitude -- an emotional state with its own positive health outcomes -- and I quickly fell behind. I decided instead (because, again, I make up the rules) to make the goal a total of 30 thank yous, one for each day of the month, and I managed to cram them all in.

In another attempt to combat unhealthy snacking, my final goal for 2019 was to convert my diet into one filled with non-processed, whole foods. Carrots and peanut butter instead of donuts; almonds instead of old Halloween candy -- you get the idea. I also declared my intention to track my progress and give myself a daily score.

"At this point, the Oxford researchers have no idea whether they have something or not," Offit said. "You just get so tired of this 'science by press release.' "

There are currently 10 vaccines in human clinical trials worldwide, according to the World Health Organization. Four of the teams are in the United States: Moderna, Pfizer, Inovio and Novavax.

Moderna CEO Stéphane Bancel referred to the results as "positive interim Phase 1 data" and that "the Moderna team continues to focus on moving as fast as safely possible to start our pivotal Phase 3 study in July."

Moderna is collaborating on its vaccine development with the National Institute of Allergy and Infectious Diseases. Dr. Anthony Fauci, the director of NIAID, said while Moderna's numbers were limited, "it was good news" and he was "cautiously optimistic" about the vaccine.

Inovio and Moderna have said they expect their large-scale clinical trials, known as Phase 3 trials, to last around six months. Pfizer hasn't given a timetable for its Phase 3 trial.

"I've not seen anyone wrap up a Phase 3 trial in a month to six weeks," said Dr. Saad Omer, a Yale University infectious disease expert who's done clinical trials on polio, pertussis and influenza vaccines. "We need to benchmark this against realistic expectations."

"I buy that this is a pandemic and we may need to show progress and show steps, and I'm OK with making forecasts if decision makers want that, but do it with a level of uncertainty, because that's what's warranted," said Omer, director of the Yale Institute for Global Health.

One big stumbling block for any vaccine trial is that Covid-19 infection rates in many areas of the world are flattening out or declining.

The Oxford vaccine uses what's called an adenovirus vector. Adenoviruses cause the common cold, but in this case, the adenoviruses are weakened and modified to deliver genetic material that codes for a protein from the novel coronavirus. The body then produces that protein and, ideally, develops an immune response to it.

"Compared to previous vaccines, this method is more robust, more versatile, and yet, equally efficient," according to the blog, which notes that the Bill & Melinda Gates Foundation invested $53 million in a German biotech company that specializes in RNA vaccines.

Inovio's technology uses a brief electrical pulse to deliver plasmids, or small pieces of genetic information, into human cells. Inovio says those cells then produce the vaccine, which leads to an immune response.

On April 19, the BBC's Andrew Marr said he asked Gilbert "if it's guaranteed that a workable vaccine can actually be produced."

"Nobody can be absolutely sure it's possible. That's why we have to do trials. We have to find out. I think the prospects are very good, but it's clearly not completely certain,"

"It certainly worked in monkeys," Oxford's Hill told CNN's Burnett May 15. "That was quite an impressive impact and that was our first try, if you like, with a standard dose, a single dose of vaccine."

"As vaccine researchers like to say, mice lie and monkeys exaggerate," Offit said.

"Now researchers can't wait to step out to the microphone -- and there are so many microphones out there -- to say, 'I've got it! This looks really good!' " Offit said.

Multiple health care workers on Thursday debunked a statement from a White House adviser that the media is overstating the need for personal protective equipment in hospitals amid the novel coronavirus pandemic.

Though Hoover’s settings bop around America from Boston to New York to Texas to Vermont, the only contextual references pertain to pop culture, social media and the occasional local attraction.

Politics are confined to the daunting gulf between haves and have-nots, and even when Hoover’s striving heroines find themselves among the haves, their hearts remain forever with the have-nots.

In these novels what matters more than anything else is hardship: Hardship is everywhere, women must suffer, women can heal, and those who make it through all this have the capacity to find themselves/love/happiness. The reader can’t help feeling that the heroine/Hoover is speaking to me/for me/like me.

Fiction of this sort reflects a strain in the culture that has shifted from a fascination with the other — the rich, the powerful, the exclusive — to a more inward preoccupation with the self and the desire to see oneself reflected in the stories one consumes

Women’s popular fiction of the ’80s, when the glitter and glamour of “Dallas” and “Dynasty” dominated prime-time TV, offers a sharp contrast. In best sellers of that period, the settings jetted from Monte Carlo to Capri to Rodeo Drive, populated by the rich, famous and destined-to-be. Heroines could have been peeled off the cover of Cosmopolitan magazine

As with TikTok testimonials of adolescent mental health challenges and group-chat confessions, it’s about “relatability” and the willingness to reveal all. Even celebrities must bare all

I never shed a tear while reading Sheldon, but that wasn’t the point. The point was exuberant voyeurism, the literary equivalent of “Lifestyles of the Rich and Famous.” The heroines’ lives were nothing like mine nor were they meant to be. That’s what made them so absurdly entertaining.

Colleen Hoover paints on a more intimate canvas. Her stories aren’t about attaining worldly power on a grand scale, but about finding power within

Hoover offers readers an emotional road map to recovery from imposter syndrome, domestic abuse, betrayal, victimization. It’s a very different kind of achievement.

In a country where economic inequalities can seem insurmountable and systems of power ever more remote, this may be the best her hard-knock heroines — and readers — can hope for.

For readers invested in characters who are like themselves — if perhaps more beautiful and with more exciting sex lives — the emotional payoff can still feel hard-earned. And, just possibly, the story could happen to them.

The novel probes how nothing in life is fixed, including the legacies of the dead and the stories we tell about our pas

“The study of history shouldn’t be backward looking,” explains a historian in “Halcyon.” “To matter, it has to take us forward.”

Ackerman was in college on Sept. 11, 2001, but what he remembers more vividly is watching the premiere of the TV miniseries “Band of Brothers” the previous Sunday. “If you wanted to know the zeitgeist in the U.S. at the time, it was this very sentimental view of World War II,” he says. “There was this nostalgia for a time where we’re the good guys, they’re the bad guys, and we’re going to liberate oppressed people.”

Ackerman, who also covers wars and veteran affairs as a journalist, says that America’s backing of Ukraine is essential in the face of what he calls “an authoritarian axis rising up in the world, with China, Russia and Iran.” Were the country to offer similar help to Taiwan in the face of an invasion from China, he notes, having some air bases in nearby Afghanistan would help, but the U.S. gave those up in 2021.

With Islamic fundamentalists now in control of places where he lost friends, he says he is often asked if he regrets his service. “When you are a young man and your country goes to war, you’re presented with a choice: You either fight or you don’t,” he writes in his 2019 memoir “Places and Names.” “I don’t regret my choice, but maybe I regret being asked to choose.”

Serving in the military at a time when wars are no longer generation-defining events has proven alienating for Ackerman. “When you’ve got wars with an all-volunteer military funded through deficit spending, they can go on forever because there are no political costs

The catastrophic withdrawal from Afghanistan in 2021, which Ackerman covers in his recent memoir “The Fifth Act,” compounded this moral injury. “The fact that there has been so little government support for our Afghan allies has left it to vets to literally clean this up,” he says, noting that he still fields requests for help on WhatsApp. He adds that unless lawmakers act, the tens of thousands of Afghans currently living in the U.S. on humanitarian parole will be sent back to Taliban-held Afghanistan later this year: “It’s very painful to see how our allies are treated.”

Looking back on America’s misadventures in Iraq, Afghanistan and elsewhere, he notes that “the stories we tell about war are really important to the decisions we make around war. It’s one reason why storytelling fills me with a similar sense of purpose.”

“We don’t talk about the world and our place in it in a holistic way, or a strategic way,” Ackerman says. “We were telling a story about ending America’s longest war, when the one we should’ve been telling was about repositioning ourselves in a world that’s becoming much more dangerous,” he adds. “Our stories sometimes get us in trouble, and we’re still dealing with that trouble today.”

Something similar might be said about “The Maniac,” Benjamín Labatut’s new novel, whose designated Prometheus is the Hungarian-born polymath John von Neumann, a pioneer of A.I. as well as an originator of game theory.

both narratives are grounded in fact, using the lives and ideas of real people as fodder for allegory and attempting to write a new mythology of the modern world.

Oppenheimer wasn’t a principal author of that theory. Those scientists, among them Niels Bohr, Erwin Schrödinger and Werner Heisenberg, were characters in Labatut’s previous novel, “When We Cease to Understand the World.” That book provides harrowing illumination of a zone where scientific insight becomes indistinguishable from madness or, perhaps, divine inspiration. The basic truths of the new science seem to explode all common sense: A particle is also a wave; one thing can be in many places at once; “scientific method and its object could no longer be prised apart.”

More than most intellectual bastions, the institute is a house of theory. The Promethean mad scientists of the 19th century were creatures of the laboratory, tinkering away at their infernal machines and homemade monsters. Their 20th-century counterparts were more likely to be found at the chalkboard, scratching out our future in charts, equations and lines of code.

The consequences are real enough, of course. The bombs dropped on Hiroshima and Nagasaki killed at least 100,000 people. Their successor weapons, which Oppenheimer opposed, threatened to kill everybody els

on Neumann and Oppenheimer were close contemporaries, born a year apart to prosperous, assimilated Jewish families in Budapest and New York. Von Neumann, conversant in theoretical physics, mathematics and analytic philosophy, worked for Oppenheimer at Los Alamos during the Manhattan Project. He spent most of his career at the Institute for Advanced Study, where Oppenheimer served as director after the war.

the intellectual drama of “Oppenheimer” — as distinct from the dramas of his personal life and his political fate — is about how abstraction becomes reality. The atomic bomb may be, for the soldiers and politicians, a powerful strategic tool in war and diplomacy. For the scientists, it’s something else: a proof of concept, a concrete manifestation of quantum theory.

. Oppenheimer’s designation as Prometheus is precise. He snatched a spark of quantum insight from those divinities and handed it to Harry S. Truman and the U.S. Army Air Forces.

Labatut’s account of von Neumann is, if anything, more unsettling than “Oppenheimer.” We had decades to get used to the specter of nuclear annihilation, and since the end of the Cold War it has been overshadowed by other terrors. A.I., on the other hand, seems newly sprung from science fiction, and especially terrifying because we can’t quite grasp what it will become.

Von Neumann, who died in 1957, did not teach machines to play Go. But when asked “what it would take for a computer, or some other mechanical entity, to begin to think and behave like a human being,” he replied that “it would have to play, like a child.”

MANIAC. The name was an acronym for “Mathematical Analyzer, Numerical Integrator and Computer,” which doesn’t sound like much of a threat. But von Neumann saw no limit to its potential. “If you tell me precisely what it is a machine cannot do,” he declared, “then I can always make a machine which will do just that.” MANIAC didn’t just represent a powerful new kind of machine, but “a new type of life.”

If Oppenheimer took hold of the sacred fire of atomic power, von Neumann’s theft was bolder and perhaps more insidious: He stole a piece of the human essence. He’s not only a modern Prometheus; he’s a second Frankenstein, creator of an all but human, potentially more than human monster.

“Technological power as such is always an ambivalent achievement,” Labatut’s von Neumann writes toward the end of his life, “and science is neutral all through, providing only means of control applicable to any purpose, and indifferent to all. It is not the particularly perverse destructiveness of one specific invention that creates danger. The danger is intrinsic. For progress there is no cure.”

, we know from the science of linguistics and the philosophy of knowledge that they differ profoundly from how humans reason and use language. These differences place significant limitations on what these programs can do, encoding them with ineradicable defects.

It is at once comic and tragic, as Borges might have noted, that so much money and attention should be concentrated on so little a thing — something so trivial when contrasted with the human mind, which by dint of language, in the words of Wilhelm von Humboldt, can make “infinite use of finite means,” creating ideas and theories with universal reach.

The human mind is not, like ChatGPT and its ilk, a lumbering statistical engine for pattern matching, gorging on hundreds of terabytes of data and extrapolating the most likely conversational response or most probable answer to a scientific question

the human mind is a surprisingly efficient and even elegant system that operates with small amounts of information; it seeks not to infer brute correlations among data points but to create explanations

such programs are stuck in a prehuman or nonhuman phase of cognitive evolution. Their deepest flaw is the absence of the most critical capacity of any intelligence: to say not only what is the case, what was the case and what will be the case — that’s description and prediction — but also what is not the case and what could and could not be the case

Those are the ingredients of explanation, the mark of true intelligence.

Here’s an example. Suppose you are holding an apple in your hand. Now you let the apple go. You observe the result and say, “The apple falls.” That is a description. A prediction might have been the statement “The apple will fall if I open my hand.”

an explanation is something more: It includes not only descriptions and predictions but also counterfactual conjectures like “Any such object would fall,” plus the additional clause “because of the force of gravity” or “because of the curvature of space-time” or whatever. That is a causal explanation: “The apple would not have fallen but for the force of gravity.” That is thinking.

The crux of machine learning is description and prediction; it does not posit any causal mechanisms or physical laws

any human-style explanation is not necessarily correct; we are fallible. But this is part of what it means to think: To be right, it must be possible to be wrong. Intelligence consists not only of creative conjectures but also of creative criticism. Human-style thought is based on possible explanations and error correction, a process that gradually limits what possibilities can be rationally considered.

ChatGPT and similar programs are, by design, unlimited in what they can “learn” (which is to say, memorize); they are incapable of distinguishing the possible from the impossible.

Whereas humans are limited in the kinds of explanations we can rationally conjecture, machine learning systems can learn both that the earth is flat and that the earth is round. They trade merely in probabilities that change over time.

For this reason, the predictions of machine learning systems will always be superficial and dubious.

some machine learning enthusiasts seem to be proud that their creations can generate correct “scientific” predictions (say, about the motion of physical bodies) without making use of explanations (involving, say, Newton’s laws of motion and universal gravitation). But this kind of prediction, even when successful, is pseudoscienc

While scientists certainly seek theories that have a high degree of empirical corroboration, as the philosopher Karl Popper noted, “we do not seek highly probable theories but explanations; that is to say, powerful and highly improbable theories.”

The theory that apples fall to earth because mass bends space-time (Einstein’s view) is highly improbable, but it actually tells you why they fall. True intelligence is demonstrated in the ability to think and express improbable but insightful things.

This means constraining the otherwise limitless creativity of our minds with a set of ethical principles that determines what ought and ought not to be (and of course subjecting those principles themselves to creative criticism)

True intelligence is also capable of moral thinking

To be useful, ChatGPT must be empowered to generate novel-looking output; to be acceptable to most of its users, it must steer clear of morally objectionable content

In 2016, for example, Microsoft’s Tay chatbot (a precursor to ChatGPT) flooded the internet with misogynistic and racist content, having been polluted by online trolls who filled it with offensive training data. How to solve the problem in the future? In the absence of a capacity to reason from moral principles, ChatGPT was crudely restricted by its programmers from contributing anything novel to controversial — that is, important — discussions. It sacrificed creativity for a kind of amorality.

Here, ChatGPT exhibits something like the banality of evil: plagiarism and apathy and obviation. It summarizes the standard arguments in the literature by a kind of super-autocomplete, refuses to take a stand on anything, pleads not merely ignorance but lack of intelligence and ultimately offers a “just following orders” defense, shifting responsibility to its creators.

In short, ChatGPT and its brethren are constitutionally unable to balance creativity with constraint. They either overgenerate (producing both truths and falsehoods, endorsing ethical and unethical decisions alike) or undergenerate (exhibiting noncommitment to any decisions and indifference to consequences). Given the amorality, faux science and linguistic incompetence of these systems, we can only laugh or cry at their popularity.

“Good” artists instinctively exclude elements of what they know to be part of real life if they feel it may be “bad,” artistically speaking. The prudish Victorians regarded sexual language in fiction that way. Charles Dickens, obviously, knew that people have sex, but he would never spell such a thing out in a novel, even though he knew dirty language was part of real life (especially among the lowlifes he sometimes wrote about, like Fagin and company). It was “bad.” It may have been “bad” in a different sense—as in indecent, improper—but it was “bad” artistically as well, in that his sense of his audience kept him from being too graphic or explicit, either in scenes or dialogue. Meanwhile, Dickens was at liberty to engineer a scene in which, say, a tuberculosis-stricken orphan switches places at the guillotine with a virginal seamstress. Today, you can put all sorts of explicit sexual references in fiction, and the average critic won’t chide you for immorality or indecency; sentimentality will get you panned every time.

The critical temperament of an age shapes an age’s creativity not just in the supply-demand way, motivating writers to produce what is praised and valued by critics and readers. The critical temperament actually blocks off areas of life to create a portrayal of the world that fits its idea of the world. So a prudish era like the Victorian will target immorality—and a cynical or ironic era like ours will target sentimentality.

"The twenties were the highest peak of joy-related words that we see," he says. "They really were roaring." But then there came 1941, which, of course, marked the beginning of America's entry into World War II. It doesn't take a historian to see that peaks and valleys like these roughly mirror the major economic and social events of the century. "In 1941, sadness is at its peak," Bently says.

They weren't just novels or books about current events, Bentley says. Many were books without clear emotional content — technical manuals about plants and animals, for example, or automotive repair guides. "It's not like the change in emotion is because people are writing about the Depression, and people are writing about the war," he says. "There might be a little bit of that, but this is just, kind of, averaged over all books and it's just kind of creeping in."

Generally speaking the usage of these commonly known emotion words has been in decline over the 20th century," Bentley says. We used words that expressed our emotions less in the year 2000 than we did 100 years earlier — words about sadness, and joy, and anger, and disgust and surprise. In fact, there is only one exception that Bentley and his colleagues found: fear. "The fear-related words start to increase just before the 1980s," he says.

For psychologists, he says, there are only a handful of ways to try to understand what is actually going on with somebody emotionally. "One is what a person says," Pennebaker explains, "kind of the 'self report' of emotion. Another might be the physiological links, and the third is what slips out when they're talking to other people, when they're writing a book or something like that."

This suggests that we imagine a complex reality in which things might be true — materially, spiritually, psychologically

“Inventive pretend,” in which children pretend the fantastic or impossible (enchanted princesses, dragon hunters) “is rarely — if ever — observed in non-industrialized or traditional cultures,”

Westerners, by contrast, not only tolerate fantasy play but actively encourage it, for adults as well as for children. We are novel readers, movie watchers and game players.

Science leads us to draw a sharp line between what is real and what is unreal. At the same time, we live in an age in which we are exquisitely aware that there are many theories, both religious and scientific, to explain the world, and many ways to be human.

Probably fiction does for us what the vision of Aslan did for Bob: it helps us to learn what we find emotionally true in the face of irreconcilable contradictions.

fiction teaches us how to think about what we take to be true. In the cacophony of an information-soaked age, we need it.

hypnosis can, in certain circumstances, result in the distortion of memory.

Initially, the neighbour told police she saw Trochym on the afternoon of Thursday, Oct. 15, 1992,but after she underwent hypnosis at the request of police, she remembered she sawthe accusedleave on Wednesday afternoon.

In its ruling, the court said the dangers posed by problems with the evidence could deprive an accused of a fair trial.

But dissenting judges, in their reasons, expressed concern about the majority ruling in which hypnosis is described as a "novel science" and "hypnotically refreshed memories" are now consideredinadmissible as evidence. "This ignores the fact that the technique has been used in Canada for almost 30 years, and has been employed in Canadian criminal investigations to assist in memory retrieval of both Crown and defence witnesses for a similar amount of time," they wrote. "Hypnosis is not new science, nor is its use in forensic investigation new."

The Sinclair group's NAD paper drew attention partly because it showed a novel way that NAD and sirtuins work together. The researchers discovered that cells' nuclei send signals to mitochondria that are needed to maintain their normal operation. SIRT1 helps insure the signals get through. When NAD levels drop, as they do with aging, SIRT1 activity falls off, which in turn makes the crucial signals fade, leading to mitochondrial dysfunction and all the ill effects that go with it.

Test-tube and rodent studies also suggest that pterostilbene is more potent than resveratrol when it comes to improving brain function, warding off various kinds of cancer and preventing heart disease.

Just as the loss of a species decreases the richness of an ecosystem, the addition of new animals could achieve the opposite effect.

National Geographic Society hosted a larger conference to debate the scientific and ethical questions raised by the prospect of “de-extinction.

“De-extinction went from concept to potential reality right before our eyes,

“This may be the biggest attraction and possibly the biggest benefit of de-extinction. It would surely be very cool to see a living woolly mammoth.”

less scientific, if more persuasive, argument was advanced by the ethicist Hank Greely and the law professor Jacob Sherkow, both of Stanford. De-extinction should be pursued, they argued in a paper published in Science, because it would be really

They will replace chunks of band-tailed-pigeon DNA with synthesized chunks of passenger-pigeon DNA, until the cell’s genome matches their working passenger-pigeon genome.

Scientists predict that changes made by human beings to the composition of the atmosphere could kill off a quarter of the planet’s mammal species, a fifth of its reptiles and a sixth of its birds by 2050

This cloning method, called somatic cell nuclear transfer, can be used only on species for which we have cellular material.

There is a shortcut. The genome of a closely related species will have a high proportion of identical DNA, so it can serve as a blueprint, or “scaffold.”

By comparing the fragments of passenger-pigeon DNA with the genomes of similar species, researchers can assemble an approximation of an actual passenger-pigeon genome.

“We’ve framed it in terms of conservation,”

the genome will have to be inscribed into a living cell.

As with any translation, there may be errors of grammar, clumsy phrases and perhaps a few missing passages, but the book will be legible. It should, at least, tell a good story.

MAGE (Multiplex Automated Genome Engineering). MAGE is nicknamed the “evolution machine” because it can introduce the equivalent of millions of years of genetic mutations within minutes

Developmental and behavioral biologists would take over, just in time to answer some difficult questions. Chicks imitate their parents’ behavior. How do you raise a passenger pigeon without parents of its own species? And how do you train band-tailed pigeons to nurture the strange spawn that emerge from their eggs; chicks that, to them, might seem monstrous: an avian Rosemary’s Baby?

For endangered species with tiny populations, scientists would introduce genetic diversity to offset inbreeding.

They will try to alter the birds’ diets, migration habits and environment. The behavior of each subsequent generation will more closely resemble that of their genetic cousins.

“There’s always this fear that somehow, if we do it, we’re going to accidentally make something horrible, because only nature can really do it right. But nature is totally random. Nature makes monsters. Nature makes threats. Many of the things that are most threatening to us are a product of nature. Revive & Restore is not going to tip the balance in any way.”

For species threatened by contagion, an effort would be made to fortify their DNA with genes that make them disease-resistant

This optimistic, soft-focus fantasy of de-extinction, while thrilling to Ben Novak, is disturbing to many conservation biologists, who consider it a threat to their entire discipline and even to the environmental movement.

The first question posed by conservationists addresses the logic of bringing back an animal whose native habitat has disappeared. Why go through all the trouble just to have the animal go extinct all over again?

There is also anxiety about disease

“If you recreate a species genetically and release it, and that genotype is based on a bird from a 100-year-old environment, you probably will increase risk.”

The scientific term for this type of genetic intervention is “facilitated adaptation.”

De-extinction also poses a rhetorical threat to conservation biologists. The specter of extinction has been the conservation movement’s most powerful argument. What if extinction begins to be seen as a temporary inconvenience?

De-extinction suggests that we can technofix our way out of environmental issues generally, and that’s very, very bad.

How will we decide which species to resurrect?

Philip Seddon recently published a 10-point checklist to determine the suitability of any species for revival, taking into account causes of its extinction, possible threats it might face upon resurrection and man’s ability to destroy the species “in the event of unacceptable ecological or socioeconomic impacts.”

But the most visceral argument against de-extinction is animal cruelty.

“Is it fair to do this to these animals?” Shapiro asked. “Is ‘because we feel guilty’ a good-enough reason?” Stewart Brand made a utilitarian counterargument: “We’re going to go through some suffering, because you try a lot of times, and you get ones that don’t take. On the other hand, if you can bring bucardos back, then how many would get to live that would not have gotten to live?”

In “How to Permit Your Mammoth,” published in The Stanford Environmental Law Journal, Norman F. Carlin asks whether revived species should be protected by the Endangered Species Act or regulated as a genetically modified organism.

He concludes that revived species, “as products of human ingenuity,” should be eligible for patenting.

The term “de-extinction” is misleading. Passenger pigeons will not rise from the grave

Our understanding of the passenger pigeon’s behavior derives entirely from historical accounts.

There is no authoritative definition of “species.” The most widely accepted definition describes a group of organisms that can procreate with one another and produce fertile offspring, but there are many exceptions.

Theseus’ ship, therefore, “became a standing example among the philosophers . . . one side holding that the ship remained the same, and the other contending that it was not the same.”

What is coming will go well beyond the resurrection of extinct species. For millenniums, we have customized our environment, our vegetables and our animals, through breeding, fertilization and pollination. Synthetic biology offers far more sophisticated tools. The creation of novel organisms, like new animals, plants and bacteria, will transform human medicine, agriculture, energy production and much else.

“reversification” to describe the phenomenon. “I mean by it a process in which words come, through a process of evolution and innovation, to have a meaning that is opposite to, or at least very different from, their initial sense,”

the word “enable” had a dubious cast in the common parlance of therapy and gossip: an enabler was someone who handed the broody tippler a fresh cocktail; to enable was to unleash the codependent. Now it’s a technological upgrade

To have something liked online is not as great as having something actually liked. It doesn’t even necessarily mean someone enjoyed it — it might simply mean, “Got it,” or more wanly, “This provoked some kind of feeling, however minor.”

To tag someone online is a far nastier enterprise. Anyone can resurface disparaging photographic evidence of youthful folly and post it on a social network, “tagging” it with the unsuspecting’s name.

Most people think long and hard about their favorite movie, novel, people and even color. Online, favorites are not so special. To “favorite” (now a verb) something on Twitter is to say, in effect, “I saw this thing and liked it O.K., but not enough to retweet it.” Or a tepid “I see you wrote something about me and I will acknowledge that by favoriting. But expect nothing more.”

Even for adults, sharing has historically been considered a commendable activity, no matter the tangled motivations. Sharing in Internet parlance? Pure egotism. Check out my 6-year-old on the viola. Don’t you wish you were this attractive at 41?

Being a star in real life signifies tremendous professional success or, at the very least, celebrity; to “star” something on Gmail means you need to write back.