New test uses a single drop of blood to reveal entire history of viral infections | Sci... - 0 views
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Researchers have developed a cheap and rapid test that reveals a person’s full history of viral infections from a single drop of blood.
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The test allows doctors to read out a list of the viruses that have infected, or continue to infect, patients even when they have not caused any obvious symptoms. The technology means that GPs could screen patients for all of the viruses capable of infecting people
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When a droplet of blood from a patient is mixed with the modified viruses, any antibodies they have latch on to human virus proteins they recognise as invaders. The scientists then pull out the antibodies and identify the human viruses from the protein fragments they have stuck to.
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In a demonstration of the technology, the team analysed blood from 569 people in the US, South Africa, Thailand and Peru. The test found that, on average, people had been infected with 10 species of viruses, though at least two people in the trial had histories of 84 infections from different kinds of viruses.
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The test could bring about major benefits for organ transplant patients. One problem that can follow transplant surgery is the unexpected reawakening of viruses that have lurked inactive in the patient or donor for years. These viruses can return in force when the patient’s immune system is suppressed with drugs to prevent them rejecting the organ. Standard tests often fail to pick up latent viruses before surgery, but the VirScan procedure could reveal their presence and alert doctors and patients to the danger.