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Although previous work had indirectly suggested that changing mitochondrial function affected lifespan, “this is the first clear demonstration [that it] extends mouse lifespan,” Miller added.

well known that mitochondria are linked to health. Some evidence suggests that inhibiting mitochondrial function can be harmful—as in the case of diabetes or obesity—but earlier data from nematodes and fruit flies also suggest a link to lifespan increase. The latest findings are a step toward untangling one of the current debates in the field—whether inhibiting mitochondrial function is detrimental or beneficial,

The average lifespan of BXD mice range from 1 year to almost 2.5 years. The researchers were able to link 3 genes to longevity variability, including mitochondrial ribosomal protein S5 (Mrps5), which encodes a protein integral to mitochondrial protein synthesis. They found that BXD strains with 50 percent less Mrps5 expression lived about 250 days longer than BXD mice with more robust Mrps5 expression.

Thirty years were added to average life expectancy in the 20th century, and rather than imagine the scores of ways we could use these years to improve quality of life, we tacked them all on at the end. Only old age got longer.

As a result, most people are anxious about the prospect of living for a century. Asked about aspirations for living to 100, typical responses are “I hope I don’t outlive my money” or “I hope I don’t get dementia.”

Each generation is born into a world prepared by its ancestors with knowledge, infrastructure and social norms. The human capacity to benefit from this inherited culture afforded us such extraordinary advantages that premature death was dramatically reduced in a matter of decades. Yet as longevity surged, culture didn’t keep up

Spanish for "beautiful hill," Loma Linda, California is nestled between mountain peaks in the middle of the San Bernardino Valley. The city is known as an epicenter of health and wellness, with more than 900 physicians on the campus of Loma Linda University and Medical Center.

Experts say that's because Loma Linda has one of the highest concentrations of Seventh-day Adventists in the world. The religion mandates a healthy lifestyle and a life of service to the church and community, which contributes to their longevity.

'I never had stress'"As far as I am concerned, stress is a manufactured thing," Dr. Ellsworth Wareham told CNN's Chief Medical Correspondent Dr. Sanjay Gupta in 2015 as part of a Vital Signs special on blue zones. Read MoreWareham was 100 years old at the time and still mowed his front yard.

Chris published a pathbreaking study showing that optimists live longer than pessimists

he thought a lot about how each of us can brighten our outlook and bring meaning and purpose into our lives. (Having a sense of purpose, he was quick to point out, is yet another positive mental element that is correlated with longevity.)

'Other people matter' was his trademark phrase, and he was one of those unique individuals who actually walked the walk, didn't just talk the talk.

As the car hummed along and we relived his spiritual journey, I asked Lynch what he really believed. Did he see Transcendental Meditation as simply a technique for relaxation, perfect for young Hollywood actresses, or rather as an all-encompassing way of life, as Maharishi had encouraged — one with peace palaces and an army of meditators fomenting world peace? Lynch paused, and then spoke for more than five minutes, explaining that T.M. was the answer for all seeking true inner happiness. He ended with this thought: “Things like traumatic stress and anxiety and tension and sorrow and depression and hate and bitter, selfish anger and fear start to lift away. And that’s a huge sense of freedom when that heavy weight of negativity begins to lift. So it’s like gold flowing in from within and garbage going out. The things in life that used to almost kill you, stress you, depress you, make you sad, make you afraid — they have less and less power. It’s like you’re building up a flak jacket of protection. You’re starting to glow with this from within.”

I still meditate. For 20 minutes or more, twice a day, I’m able to step back from the news scroll of thoughts and be truly quiet. I use T.M. to deal with anxiety and fatigue and to stave off occasional despair. But that’s because, in my head, I’ve managed to excise the weird flotsam of spirituality that engulfed T.M. for the first part of my life. Now, for me, it is something very simple, like doing yoga or avoiding dairy. Objectively speaking, meditation has been shown to decrease the incidence of heart attacks and strokes and increase longevity. The Department of Veterans Affairs and the Department of Defense commissioned studies to determine whether T.M. can help veterans alleviate post-traumatic stress disorder. Thanks to the David Lynch foundation, low-performing public schools have instituted “Quiet Time,” an elective 10 minutes, twice a day, during which students meditate, with some encouraging results.

The office of the David Lynch Foundation for Consciousness-Based Education and World Peace in New York is filled with young adults, many of whom grew up practicing Transcendental Meditation. Since Lynch started spreading the good news about T.M., the number of people learning the technique has increased tenfold. Close to Lynch’s heart are those suffering from PTSD, it seems, but it is in his own industry that he has made a more visible impact. Roth, who runs the foundation, spends much of his time flying around the world as well as initiating a long list of public figures: Gwyneth Paltrow, Ellen DeGeneres, Russell Simmons, Katy Perry, Susan Sarandon, Candy Crowley, Soledad O’Brien, George Stephanopoulos and Paul McCartney’s grandchildren.

But according to Stuart Ritchie, an intelligence researcher at the University of Edinburgh, there's a massive amount of data showing that it's one of the best predictors of someone's longevity, health, and prosperity

In a new book, Intelligence: All that Matters, Ritchie persuasively argues that IQ doesn't necessarily set the limit for what we can do, but it does give us a starting point

Most people you meet are probably average, and a few are extraordinarily smart. Just 2.2 percent have an IQ of 130 or greate

Mitochondria are our cells' energy dynamos. Descended from bacteria that colonized other cells about 2 billion years, they get flaky as we age.

While it's not clear why our mitochondria fade as we age, evidence suggests that it leads to everything from heart failure to neurodegeneration,

Recent research suggests it may be possible to reverse mitochondrial decay with dietary supplements that increase cellular levels of a molecule called NAD (nicotinamide adenine dinucleotide).

As we age, our brains naturally shrink and our risk of having a stroke, dementia or Alzheimer's rise, and almost everyone experiences some kind of memory loss

Scientists know that people who exercise regularly, eat a healthy diet, avoid smoking and keep mentally stimulated generally have healthier brains

Researchers figured this out by looking at the brains of 674 people with an average age of 80. They asked these elderly people to fill out food surveys about what they ate in the last year and researchers scanned their brains. The group that ate a Mediterranean diet had heavier brains with more gray and white matter.

Every modern presidential election is at least in part defined by the cool new media breakthrough of its moment.

In 2000, there was email, and by golly was that a big change from the fax. The campaigns could get their messages in front of print and cable news reporters — who could still dominate the campaign narrative — at will,

Then 2008: Facebook made it that much easier for campaigns to reach millions of people directly,

people with solid friendships live healthier, longer lives. Friendship decreases blood pressure and stress, reduces the risk of depression and increases longevity, in large part because someone is watching out for us.

A study published in February in the British Journal of Psychology looked at 15,000 respondents and found that people who had more social interactions with close friends reported being happier—unless they were highly intelligent.

People with higher I.Q.s were less content when they spent more time with friends. Psychologists theorize that these folks keep themselves intellectually stimulated without a lot of social interaction, and often have a long-term goal they are pursuing.

experimental psychologist

research on how social interactions affect biology in humans and animals.

t women living together in a Wellesley College dormitory tended to menstruate at the same time.

Critical philosophy of race, like critical race theory in legal studies, seeks to understand the disadvantages of nonwhite racial groups in society (blacks especially) by understanding social customs, laws, and legal practices.

What’s happening in Ferguson is the result of several recent historical factors and deeply entrenched racial attitudes, as well as a breakdown in participatory democracy.

It’s too soon to tell, but “Don’t Shoot” could become a real political movement — or it could peter out as the morally outraged self-expression of the moment, like Occupy Wall Street.

Mr. Housel, 36 years old, is a blogger and venture capitalist who writes beautifully and wisely about a central truth: Money isn’t primarily a store of value. Money is a conduit of emotion and ego, carrying hopes and fears, dreams and heartbreak, confidence and surprise, envy and regret.

Investing isn’t an IQ test; it’s a test of character. Unlike the man who chucked coins into the sea, Mr. Read could defer gratification and had no need to spend big so other people wouldn’t think he was small. From such old-fashioned virtues great fortunes can be built.

Investors think of such volatility as a kind of “fine” for having made a mistake, says Mr. Housel. Instead, they should regard it as a “fee,” the unavoidable cost of participation. You never know how big the fee will be or when you will incur it, but patience can make it bearable.

Just a few months ago, the New York Times declared that "studies have shown an indisputable link between having a positive outlook and health benefits like lower blood pressure, less heart disease, better weight control and healthier blood sugar levels." Plenty of news articles present similar ideas in a stark black-and-white fashion: optimists live longer; pessimism kills.

But some research suggests that things aren't so simple. In 2016, for example, a study of more than 700,000 British women failed to find a link between happiness and longevity. Which raises the question: What makes this particular group of study participants any different? Could it be that culture plays a role -- that British people, overall, are just more tolerant and accepting of gloominess?

Even after accounting for things like a person's age, gender, socioeconomic status, and chronic health conditions, there was a significant difference between the two groups: "American adults who experience high levels of positive emotions, such as feeling 'cheerful' and 'extremely happy,' are more likely to have healthy blood-lipid profiles," explains lead study author Jiah Yoo, but the same was not true among Japanese adults.

A mini- or micro-resolution is any behavior you commit to for four weeks. And even longer-term goals to, say, eat better or learn a new skill, can be broken down into more achievable goals on the way. Before you can land on Mars, focus on landing on the moon.

To create your micro-resolutions, you can start by thinking of 12 "bad" habits or indulgences you'd like to cut back on or give up entirely. This is what I did last year for what I called my "Year of Abstinence." My plan was to learn something about myself through self-denial, and it worked: I gave up alcohol, sweets, television and nine other things, but just for a month each. The mini-resolutions were as positive as they were eye-opening.

In order to simply increase my own, general awareness, every day in January my goal was to notice something new. I kept my eyes open, looked a bit longer, stopped to read the history markers, noticing buildings or took a different route than normal -- small ways to avoid sleepwalking through life.

Science has been exploring the connection between happiness and longevity for some time. A 2011 analysis of nearly 4,000 Brits found those who said they felt content, happy or excited on a typical day were up to 35% less likely to die prematurely. In a 2016 study, a positive outlook was associated with longer life for nearly 4,000 older French men and women studied over 22 years.

According to research on the Positive Psychology Center website, striving for well-being will allow you to perform better at work, have better relationships, a stronger immune system, fewer sleep problems, lower levels of burnout, better physical health and -- you'll live longer.

"Happiness comes in different sizes and flavors," said cardiologist Dr. Alan Rozanski, a professor of medicine at the Icahn School of Medicine at Mount Sinai who studies optimism."There is the transient type, fed by such things as a walk in a park, spending time with a friend, or eating that ice cream you love," he continued. "But these feelings of happiness come and go."