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Unionization rates in the U.S. have declined for decades. "Unionization is highest in the public sector, but this has been challenged by state and local austerity since the recession in 2008-09," Warner said.

Warner said that the role of the federal government is to provide funds to states and local governments to support critical public services, such as schools and roads

While the federal government can play a redistributive role, as with the recent COVID relief package, this is less likely in states that have more corporate influence in their legislative policymaking,

"In the new political economy of place, the corporate interests undermine the potential for inclusive economic growth."

during this same period, students' self-reported narcissism levels have shot through the roof. "Many people see the current group of college students, sometimes called 'Generation Me,' " Konrath continues, "as one of the most self-centered, narcissistic, competitive, confident, and individualistic in recent history."

Reading a book carves brand-new neural pathways into the ancient cortical bedrock of our brains. It transforms the way we see the world—makes us, as Nicholas Carr puts it in his recent essay, "The Dreams of Readers," "more alert to the inner lives of others." We become vampires without being bitten—in other words, more empathic. Books make us see in a way that casual immersion in the Internet, and the quicksilver virtual world it offers, doesn't.

if society really is becoming more psychopathic, it's not all doom and gloom. In the right context, certain psychopathic characteristics can actually be very constructive. A neurosurgeon I spoke with (who rated high on the psychopathic spectrum) described the mind-set he enters before taking on a difficult operation as "an intoxication that sharpens rather than dulls the senses." In fact, in any kind of crisis, the most effective individuals are often those who stay calm—who are able to respond to the exigencies of the moment while at the same time maintaining the requisite degree of detachment.

mental toughness isn't the only characteristic that Special Forces soldiers have in common with psychopaths. There's also fearlessness.

I ask Andy whether he ever felt any regret over anything he'd done. Over the lives he'd taken on his numerous secret missions around the world. "No," he replies matter-of-factly, his arctic-blue eyes showing not the slightest trace of emotion. "You seriously don't think twice about it. When you're in a hostile situation, the primary objective is to pull the trigger before the other guy pulls the trigger. And when you pull it, you move on. Simple as that. Why stand there, dwelling on what you've done? Go down that route and chances are the last thing that goes through your head will be a bullet from an M16. "The regiment's motto is 'Who Dares Wins.' But sometimes it can be shortened to 'F--- It.' "

one of the things that we know about psychopaths is that the light switches of their brains aren't wired up in quite the same way as the rest of ours are—and that one area particularly affected is the amygdala, a peanut-size structure located right at the center of the circuit board. The amygdala is the brain's emotion-control tower. It polices our emotional airspace and is responsible for the way we feel about things. But in psychopaths, a section of this airspace, the part that corresponds to fear, is empty.

Turn down the signals to the amygdala, of course, and you're well on the way to giving someone a psychopath makeover. Indeed, Liane Young and her team in Boston have since kicked things up a notch and demonstrated that applying TMS to the right temporoparietal junction—a neural ZIP code within that neighborhood—has significant effects not just on lying ability but also on moral-reasoning ability: in particular, ascribing intentionality to others' actions.

at an undisclosed moment sometime within the next 60 seconds, the image you see at the present time will change, and images of a different nature will appear on the screen. These images will be violent. And nauseating. And of a graphic and disturbing nature. "As you view these images, changes in your heart rate, skin conductance, and EEG activity will be monitored and compared with the resting levels that are currently being recorded

"OK," says Nick. "Let's get the show on the road." He disappears behind us, leaving Andy and me merrily soaking up the incontinence ad. Results reveal later that, at this point, as we wait for something to happen, our physiological output readings are actually pretty similar. Our pulse rates are significantly higher than our normal resting levels, in anticipation of what's to come. But with the change of scene, an override switch flips somewhere in Andy's brain. And the ice-cold Special Forces soldier suddenly swings into action. As vivid, florid images of dismemberment, mutilation, torture, and execution flash up on the screen in front of us (so vivid, in fact, that Andy later confesses to actually being able to "smell" the blood: a "kind of sickly-sweet smell that you never, ever forget"), accompanied not by the ambient spa music of before but by blaring sirens and hissing white noise, his physiological readings start slipping into reverse. His pulse rate begins to slow. His GSR begins to drop, his EEG to quickly and dramatically attenuate. In fact, by the time the show is over, all three of Andy's physiological output measures are pooling below his baseline.

Nick has seen nothing like it. "It's almost as if he was gearing himself up for the challenge," he says. "And then, when the challenge eventually presented itself, his brain suddenly responded by injecting liquid nitrogen into his veins. Suddenly implemented a blanket neural cull of all surplus feral emotion. Suddenly locked down into a hypnotically deep code red of extreme and ruthless focus." He shakes his head, nonplused. "If I hadn't recorded those readings myself, I'm not sure I would have believed them," he continues. "OK, I've never tested Special Forces before. And maybe you'd expect a slight attenuation in response. But this guy was in total and utter control of the situation. So tuned in, it looked like he'd completely tuned out."

My physiological output readings, in contrast, went through the roof. Exactly like Andy's, they were well above baseline as I'd waited for the carnage to commence. But that's where the similarity ended. Rather than go down in the heat of battle, in the midst of the blood and guts, mine had appreciated exponentially. "At least it shows that the equipment is working properly," comments Nick. "And that you're a normal human being."

TMS can't penetrate far enough into the brain to reach the emotion and moral-reasoning precincts directly. But by damping down or turning up the regions of the cerebral cortex that have links with such areas, it can simulate the effects of deeper, more incursive influence.

Before the experiment, I'd been curious about the time scale: how long it would take me to begin to feel the rush. Now I had the answer: about 10 to 15 minutes. The same amount of time, I guess, that it would take most people to get a buzz out of a beer or a glass of wine.

The effects aren't entirely dissimilar. An easy, airy confidence. A transcendental loosening of inhibition. The inchoate stirrings of a subjective moral swagger: the encroaching, and somehow strangely spiritual, realization that hell, who gives a s---, anyway? There is, however, one notable exception. One glaring, unmistakable difference between this and the effects of alcohol. That's the lack of attendant sluggishness. The enhancement of attentional acuity and sharpness. An insuperable feeling of heightened, polished awareness. Sure, my conscience certainly feels like it's on ice, and my anxieties drowned with a half-dozen shots of transcranial magnetic Jack Daniel's. But, at the same time, my whole way of being feels as if it's been sumptuously spring-cleaned with light. My soul, or whatever you want to call it, immersed in a spiritual dishwasher.

So this, I think to myself, is how it feels to be a psychopath. To cruise through life knowing that no matter what you say or do, guilt, remorse, shame, pity, fear—all those familiar, everyday warning signals that might normally light up on your psychological dashboard—no longer trouble you.

I suddenly get a flash of insight. We talk about gender. We talk about class. We talk about color. And intelligence. And creed. But the most fundamental difference between one individual and another must surely be that of the presence, or absence, of conscience. Conscience is what hurts when everything else feels good. But what if it's as tough as old boots? What if one's conscience has an infinite, unlimited pain threshold and doesn't bat an eye when others are screaming in agony?

“It used to take me an hour to memorize 20 words. Now I can learn, like, 40 new words in 20 minutes.”

“I don’t know if it makes you smarter. But when you get to each new level on the math and reading tasks, it definitely builds up your self-confidence.”

. “What you care about is not an intelligence test score, but whether your ability to do an important task has really improved. That’s a chain of evidence that would be really great to have. I haven’t seen it.”

Still,a new and growing body of scientific evidence indicates that cognitive training can be effective, including that offered by commercial services.

He looked at 340 middle-school students who spent two hours a week for a semester using LearningRx exercises in their schools’ computer labs and an equal number of students who received no such training. Those who played the online games, Dr. Hill found, not only improved significantly on measures of cognitive abilities compared to their peers, but also on Virginia’s annual Standards of Learning exam.

I’ve had some kids who not only reported that they had very big changes in the classroom, but when we bring them back in the laboratory to do neuropsychological testing, we also see great changes. They show increases that would be highly unlikely to happen just by chance.”

where crosswords and Sudoku are intended to be a diversion, the games here give that same kind of reward, only they’re designed to improve your brain, your memory, your problem-solving skills.”

More than 40 games are offered by Lumosity. One, the N-back, is based on a task developed decades ago by psychologists. Created to test working memory, the N-back challenges users to keep track of a continuously updated list and remember which item appeared “n” times ago.

Despite History’s mantle of preserving and purveying an accurate picture of the past, hewing to the letter of historical accuracy wasn’t possible in the case of a dramatic series based on fragmented documentation, hence a large degree of dramatic license was employed.

“I especially had to take liberties with ‘Vikings’ because no one knows for sure what happened in the Dark Ages,” Mr. Hirst said. “Very little was written then.” The bottom line, he explained, was: “We want people to watch it. A historical account of the Vikings would reach hundreds, occasionally thousands, of people. Here we’ve got to reach millions.”

he was hard put to replicate authentic fabrics and woods. One of the biggest challenges he faced, he added, was improvising lighting sources for Viking homes and halls, which had no windows, making engaging photography of a strictly realistic interior setting impossible.

“And one of the things we want is to spend more time with people who think like us and less with people who are different,” Haidt added. “The Facebook effect isn’t trivial. But it’s catalyzing or amplifying a tendency that was already there.”

prevalent for many users are the posts we see from friends and from other people and groups we follow on the network, and this information is utterly contingent on choices we ourselves make

The Internet isn’t rigged to give us right or left, conservative or liberal — at least not until we rig it that way. It’s designed to give us more of the same, whatever that same is

So it goes with the fiction we read, the movies we watch, the music we listen to and, scarily, the ideas we subscribe to. They’re not challenged. They’re validated and reinforced.

this colors our days, or rather bleeds them of color, reducing them to a single hue.

Facebook, along with other social media, definitely conspires in this. Haidt noted that it often discourages dissent within a cluster of friends by accelerating shaming. He pointed to the enforced political correctness among students at many colleges.

Carnival barkers, conspiracy theories, willful bias and nasty partisanship aren’t anything new, and they haven’t reached unprecedented heights today. But what’s remarkable and sort of heartbreaking is the way they’re fed by what should be strides in our ability to educate ourselves.

The proliferation of cable television networks and growth of the Internet promised to expand our worlds, not shrink them. Instead they’ve enhanced the speed and thoroughness with which we retreat into enclaves of the like-minded.

there’s no argument that in an era that teems with choice, brims with niche marketing and exalts individualism to the extent that ours does, we’re sorting ourselves with a chillingly ruthless efficiency. We’ve surrendered universal points of reference. We’ve lost common ground.

Marc Dunkelman, adding that it also makes it easier for us to avoid “face-to-face interactions with diverse ideas.” He touched on this in an incisive 2014 book, “The Vanishing Neighbor,” which belongs with Haidt’s work and with “Bowling Alone,” “Coming Apart” and “The Fractured Republic” in the literature of modern American fragmentation, a booming genre all its own.

We’re less committed to, and trustful of, large institutions than we were at times in the past. We question their wisdom and substitute it with the groupthink of micro-communities, many of which we’ve formed online, and their sensibilities can be more peculiar and unforgiving.

We construct precisely contoured echo chambers of affirmation that turn conviction into zeal, passion into fury, disagreements with the other side into the demonization of it

It’s not about some sorcerer’s algorithm. It’s about a tribalism that has existed for as long as humankind has and is now rooted in the fertile soil of the Internet, which is coaxing it toward a full and insidious flower

As a child grows up, the body schema adjusts to the changing body, but its adaptability has limits.

Attention is the selective enhancement of some signals over others, such that the brain’s resources are strategically deployed.

The brain needs to control its attention, just as it controls the body.

In control theory, if a machine is to control something optimally, it needs a working model of whatever it’s controlling. The brain certainly follows this principle in controlling the body.

Just as the body schema is a surreal description of the body, so the attention schema would be a surreal description of attention.

This is called the attention schema theory, a theory that my lab has been developing and testing experimentally for the past five years. It’s a theory of why we insist with such certainty that we have subjective experience. Attention is fundamental.

During adolescence, the neurocircuitry strengthens and allows for multitasking, enhanced ability to solve problems, and the capability to process complex information. Furthermore, adolescent brain plasticity provides an opportunity to develop talents and lifelong interests; however, neurotoxic insult, trauma, chronic stress, drug abuse, and sedentary lifestyles may have a negative impact during this sensitive period of brain maturation

Language evolved to solve the crisis of visual theft and to exploit cooperation and exchange

Humans use discrete pulses of sound -- their language -- to alter the internal settings inside someone else's brain to suit an individual's interests. Because language is not a solitary pursuit, language is a form of social learning.

thousands of languages evolved

Can humans afford to have all these different languages, asks Professor Pagel. In a world where we want to promote cooperation, in a world that is more dependent than ever on cooperation to maintain and enhance humanity's levels of prosperity, multiple languages may not be practical.

languages reflect the myriad ways that the human mind perceives and responds to the world, and to lose any of them is to (slightly) diminish and limit the variety and expressive depth of human intellectual, creative and experiential capacity.

The two reports together establish the feasibility of trying to grow replacement human organs in animals, though such a goal is still far off.

Creating chimeras, especially those with human cells, may prove controversial, given the possibility that test animals could be humanized in undesirable ways. One would be if human cells should be incorporated into a pig’s brain, endowing it with human qualities. Almost no one wants a talking pig.

The ban is still in place, and it’s unclear whether the Trump administration would continue to consider lifting the moratorium or whether new objections would be raised to using public funds for this line of research.

But no one knows exactly what sequence of chemicals is required for the generation of each different tissue or organ. This may be why glassware experiments with stem cells have not yet lived up to their full promise.

Concern about human cells’ incorporation into a lower animal’s brain is not without basis. Dr. Steven Goldman of the University of Rochester Medical Center found in 2013 that mice injected with a special type of human brain cell had enhanced learning abilities.

two and a half years later, the questionnaire was given a second time to the same students.

It was then that R. T. recalled, with absolute confidence, her dorm-room experience.

She didn’t know any details of what had happened,

We don’t really remember an uneventful day the way that we remember a fight or a first kiss.

Her hope is to understand how, exactly, emotional memories behave at all stages of the remembering process: how we encode them, how we consolidate and store them, how we retrieve them.

When it comes to the central details of the event, like that the Challenger exploded, they are clearer and more accurate. But when it comes to peripheral details, they are worse. And our confidence in them, while almost always strong, is often misplaced.

Phelps has combined Neisser’s experiential approach with the neuroscience of emotional memory to explore how such memories work, and why they work the way they do.

A key element of emotional-memory formation is the direct line of communication between the amygdala and the visual cortex.

Within the brain, memories are formed and consolidated largely due to the help of a small seahorse-like structure called the hippocampus; damage the hippocampus, and you damage the ability to form lasting recollections.

Memory for the emotional scenes was significantly higher, and the vividness of the recollection was significantly greater.

hat is, if you were shocked when you saw animals, your memory of the earlier animals was also enhanced. And, more important, the effect only emerged after six or twenty-four hours: the memory needed time to consolidate.

o, if memory for events is strengthened at emotional times, why does everyone forget what they were doing when the Challenger exploded?

The strength of the central memory seems to make us confident of all of the details when we should only be confident of a few.

Our misplaced confidence in recalling dramatic events is troubling when we need to rely on a memory for something important—evidence in court, for instance

After reviewing the evidence, the committee made several concrete suggestions to changes in current procedures, including “blinded” eyewitness identification

standardized instructions to witnesses, along with extensive police training in vision and memory research as it relates to eyewitness testimony, videotaped identification, expert testimony early on in trials about the issues surrounding eyewitness reliability, and early and clear jury instruction on any prior identifications

go this route if you believe privacy is dead, but find social networking too good to miss out on.

While we should be attuned to constraints and their consequences, there are at least four problems with conceptualizing the social media user's dilemma as a version of "if you can't stand the heat, get out of the kitchen".

The efficacy of abandoning social media can be questioned when others are free to share information about you on a platform long after you've left.

Second, while abandoning a single social technology might seem easy, this "love it or leave it" strategy -- which demands extreme caution and foresight from users and punishes them for their naivete -- isn't sustainable without great cost in the aggregate. If we look past the consequences of opting out of a specific service (like Facebook), we find a disconcerting and more far-reaching possibility: behavior that justifies a never-ending strategy of abandoning every social technology that threatens privacy -- a can being kicked down the road in perpetuity without us resolving the hard question of whether a satisfying balance between protection and publicity can be found online

if your current social network has no obligation to respect the obscurity of your information, what justifies believing other companies will continue to be trustworthy over time?

Sticking with the opt-out procedure turns digital life into a paranoid game of whack-a-mole where the goal is to stay ahead of the crushing mallet. Unfortunately, this path of perilously transferring risk from one medium to another is the direction we're headed if social media users can't make reasonable decisions based on the current context of obscurity, but instead are asked to assume all online social interaction can or will eventually lose its obscurity protection.

The fourth problem with the "leave if you're unhappy" ethos is that it is overly individualistic. If a critical mass participates in the "Opt-Out Revolution," what would happen to the struggling, the lonely, the curious, the caring, and the collaborative if the social web went dark?

Our point is that there is a middle ground between reclusion and widespread publicity, and the reduction of user options to quitting or coping, which are both problematic, need not be inevitable, especially when we can continue exploring ways to alleviate the user burden of retreat and the societal cost of a dark social web.

it is easy to presume that "even if you unfriend everybody on Facebook, and you never join Twitter, and you don't have a LinkedIn profile or an About.me page or much else in the way of online presence, you're still going to end up being mapped and charted and slotted in to your rightful place in the global social network that is life." But so long it remains possible to create obscurity through privacy enhancing technology, effective regulation, contextually appropriate privacy settings, circumspect behavior, and a clear understanding of how our data can be accessed and processed, that fatalism isn't justified.

The social medium of choice for the self-absorbed appears to be Twitter. The researchers found an association between tweeting about oneself and high narcissism scores.

“We have to think about social media in a new strategic way,” he said. “It is no longer something that we can ignore. It is not a place to just wish your friends happy birthday. It is a place of business. It is a place where your career will be enhanced or degraded, depending on your use of these tools and services.”

By emphasizing a focus on the here and now, it trains the mind to stay on task and avoid distraction.

“Your ability to recognize what your mind is engaging with, and control that, is really a core strength,” said Peter Malinowski, a psychologist and neuroscientist at Liverpool John Moores University in England. “For some people who begin mindfulness training, it’s the first time in their life where they realize that a thought or emotion is not their only reality, that they have the ability to stay focused on something else, for instance their breathing, and let that emotion or thought just pass by.”

one of the most surprising findings of recent mindfulness studies is that it could have unwanted side effects. Raising roadblocks to the mind’s peregrinations could, after all, prevent the very sort of mental vacations that lead to epiphanies.

he found that having participants spend a brief period of time on an undemanding task that maximizes mind wandering improved their subsequent performance on a test of creativity. In a follow-up study, he reported that physicists and writers alike came up with their most insightful ideas while spacing out.

The trick is knowing when mindfulness is called for and when it’s not.

the higher adults scored on a measurement of mindfulness, the worse they performed on tests of implicit learning — the kind that underlies all sorts of acquired skills and habits but that occurs without conscious awareness.

“There’s so much our brain is doing when we’re not aware of it,” said the study’s leader, Chelsea Stillman, a doctoral candidate. “We know that being mindful is really good for a lot of explicit cognitive functions. But it might not be so useful when you want to form new habits.” Learning to ride a bicycle, speak grammatically or interpret the meaning of people’s facial expressions are three examples of knowledge we acquire through implicit learning

in developed countries, major and minor mental illnesses were three times as common in societies where there were bigger income differences between rich and poor. In other words, an American is likely to know three times as many people with depression or anxiety problems as someone in Japan or Germany.

One, looking at the 50 American states, discovered that after taking account of age, income and educational differences, depression was more common in states with greater income inequality

schizophrenia was about three times as common in more unequal societies as it was in more equal ones.

a wide range of mental disorders might originate in a “dominance behavioral system.” This part of our evolved psychological makeup, almost universal in mammals, enables us to recognize and respond to social ranking systems based on hierarchy and power. One brain-imaging study discovered that there were particular areas of the brain and neural mechanisms dedicated to processing social rank.

psychiatric conditions like mania and narcissism are related to our striving for status and dominance, while disorders such as anxiety and depression may involve responses to the experience of subordination

how does increasing inequality factor in? One of the important effects of wider income differences between rich and poor is to intensify the issues of dominance and subordination, and feelings of superiority and inferiority.

A new study by Dublin-based researchers of 34,000 people in 31 countries found that in countries with bigger income differences, status anxiety was more common at all levels in the social hierarchy

self-enhancement or self-aggrandizement — the tendency to present an inflated view of oneself — occurred much more frequently in more unequal societies.

In the United States, research psychologists have shown that narcissism rates, as measured by a standard academic tool known as the Narcissistic Personality Inventory, rose rapidly from the later 1980s, which would appear to track the increases in inequality

as larger differences in material circumstances create greater social distances, feelings of superiority and inferiority increase. In short, growing inequality makes us all more neurotic about “image management” and how we are seen by others.

Humans instinctively know how to cooperate and create social ties, but we also know how to engage in status competition — how to be snobs and how to talk ourselves up. We use these alternative social strategies almost every day of our lives, but crucially, inequality shifts the balance between them.

we become less nice people in more unequal societies. But we are less nice and less happy: Greater inequality redoubles status anxiety, damaging our mental health and distorting our personalities — wherever we are on the social spectrum.

Creativity moves beyond mere synthesis and evaluation and is, he says, “the higher order skill.” This has not been a sudden development. Nearly 20 years ago “creating” replaced “evaluation” at the top of Bloom’s Taxonomy of learning objectives. In 2010 “creativity” was the factor most crucial for success found in an I.B.M. survey of 1,500 chief executives in 33 industries. These days “creative” is the most used buzzword in LinkedIn profiles two years running.

The method, which is used in Buffalo State classrooms, has four steps: clarifying, ideating, developing and implementing. People tend to gravitate to particular steps, suggesting their primary thinking style.

What’s igniting campuses, though, is the conviction that everyone is creative, and can learn to be more so.

Just about every pedagogical toolbox taps similar strategies, employing divergent thinking (generating multiple ideas) and convergent thinking (finding what works).The real genius, of course, is in the how.

as content knowledge evolves at lightning speed, educators are talking more and more about “process skills,” strategies to reframe challenges and extrapolate and transform information, and to accept and deal with ambiguity.

Clarifying — asking the right question — is critical because people often misstate or misperceive a problem. “If you don’t have the right frame for the situation, it’s difficult to come up with a breakthrough,

Ideating is brainstorming and calls for getting rid of your inner naysayer to let your imagination fly.

Developing is building out a solution, and maybe finding that it doesn’t work and having to start over

Implementing calls for convincing others that your idea has value.

“the frequency and intensity of failures is an implicit principle of the course. Getting into a creative mind-set involves a lot of trial and error.”

His favorite assignments? Construct a résumé based on things that didn’t work out and find the meaning and influence these have had on your choices.

“Examine what in the culture is preventing you from creating something new or different. And what is it like to look like a fool because a lot of things won’t work out and you will look foolish? So how do you handle that?”

Because academics run from failure, Mr. Keywell says, universities are “way too often shapers of formulaic minds,” and encourage students to repeat and internalize fail-safe ideas.

“The new people who will be creative will sit at the juxtaposition of two or more fields,” she says. When ideas from different fields collide, Dr. Cramond says, fresh ones are generated.

Basic creativity tools used at the Torrance Center include thinking by analogy, looking for and making patterns, playing, literally, to encourage ideas, and learning to abstract problems to their essence.

students explore definitions of creativity, characteristics of creative people and strategies to enhance their own creativity.These include rephrasing problems as questions, learning not to instinctively shoot down a new idea (first find three positives), and categorizing problems as needing a solution that requires either action, planning or invention.

training before the age of 7 years results in changes in white-matter connectivity that may serve as a solid scaffolding upon which ongoing experience can maintain a well-connected brain infrastructure into adulthood.

musical training improves the function and connectivity of different brain regions. Musical training increases brain volume and strengthens communication between brain areas. Playing an instrument changes how the brain interprets and integrates a wide range of sensory information, especially for those who start before age 7.

Musicians have an enhanced ability to integrate sensory information from hearing, touch, and sight.The age at which musical training begins affects brain anatomy as an adult; beginning training before the age of seven has the greatest impact.Brain circuits involved in musical improvisation are shaped by systematic training, leading to less reliance on working memory and more extensive connectivity within the brain.

cross-reactive antibodies bind relatively weakly to their targets and, under normal circumstances, would probably get outcompeted by antibodies with a narrower focus but higher affinity. “For whatever reason, antibodies to the conserved regions are very rare,”

possible to skew the response towards more broadly cross-reactive antibodies, in mice, in a particular situation,”

not advocating that we use rapamycin [in humans],” said McGargill. However, her group’s discovery could point to other ways of achieving the same effect, perhaps by manipulating the immune system into producing more cross-reactive antibodies. “Maybe instead of trying to enhance the immune response, we need to dampen it a little bit, and allow it to be more diverse,