Sensory perception | Science Features | Naked Scientists - 0 views
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Deciphering how the brain processes sight and hearing could have implications for how we understand and treat conditions such as dyslexia, autism and schizophrenia.
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Through a project called SENSOCOM, she is exploring how sensory perception affects communication, focusing on the brain’s deep subcortical structures.By doing this, she and her team are exploring a part of the brain traditionally excluded by research trying to understand communication impairments found in autism spectrum disorder and dyslexia, conditions which affect around 53 million people in Europe.
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To do this they have been focusing on the sensory pathways linked to these deep structures. She and her group discovered that adults with dyslexia have weaker pathway connections between a visual subcortical structure (the left visual thalamus) with an area of the cortex called V5/MT, which is critical for the perception of visual motion. In the auditory mode, there was a similar finding. The team discovered weaker connections between the left auditory thalamus and a cortex structure linked to auditory motion, which is important for speech perception. These connections could therefore be important for reading and for predicting reading skill, according to Dr von Kriegstein.
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So how might this translate into helping people with dyslexia? This is basic science, says Prof. von Kriegstein, so first it’s crucial to understand the mechanisms behind communications disorders before developing therapy training tools, although she is optimistic these could lie within reach.
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The way the brain encodes information and in turn directs perception of that sensory experience is a highly variable process.
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The sensory overload or distorted and heightened perceptions described by schizophrenia patients, for instance, could relate to these deficits. Sensory dysfunction has also been linked to delusions and hallucinations as well as difficulties with attention and reading the emotions or tone of others – all of which can affect social interaction.
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According to Dr Fellin, decreased connectivity between nerve cells (neurons) appears to play an important role in the progression of schizophrenia. So far, Dr Fellin and his group have identified which specific neurons influence sensory responses in mouse studies, but not yet in animal models of schizophrenia, with similar investigations in glial cells - the supporting cells of the nervous system.