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So, What’s Your ‘Fauxmorbidity’?

People are racing to get vaccinated — even those who don’t yet technically qualify. And that’s good news.

After Covid-19 vaccines from Pfizer and Moderna were approved for use in late 2020, anecdotes proliferated about rich people finding ways to jump the distribution priority line.

What makes it so hard to quit?

two culprits: aspartame and caffeine. Or, to be more precise: addiction to sweetness and to caffeine. Individually, they’re bad; together, they’re an addict’s nightmare.

A 12-ounce can of regular Coke has 34 milligrams of caffeine, whereas Diet Coke has 11 milligrams more, according to Coca-Cola. (An 8-ounce cup of coffee has about 95 mg.) Artificial sweeteners activate the brain’s reward system, but only about half as much as regular sugar, said Dr. Peeke. Faux sugar doesn’t pack the same wallop as the real stuff, so it keeps you wanting more and more.

It’s no surprise that when a person gets a diagnosis of heart disease, cancer or some other life-limiting or life-threatening physical ailment, they become anxious or depressed.

But the reverse can also be true: Undue anxiety or depression can foster the development of a serious physical disease, and even impede the ability to withstand or recover from one.

The human organism does not recognize the medical profession’s artificial separation of mental and physical ills. Rather, mind and body form a two-way street.

The problem with anxiety — as Marcus Aurelius would acknowledge — is that, by definition, it’s irrational; in that regard, it’s not so different from the almost irresistible impulse to jump that seizes me every time I find myself on a 50th-floor balcony,

it’s uncanny how often we let ourselves out of the Garden by worrying about something that, if it did happen, would quicken us into a response much more practical than worry

All the real challenges of my, or any, life — the forest fire that did indeed destroy my home and everything in it; the car crash that suddenly robbed dozens of us of a cherished friend; my 13-year-old daughter’s diagnosis of cancer in its third stage — came out of the blue; they’re just what I had never thought to worry about

One-fifth of Americans are religiously unaffiliated — higher than at any time in recent U.S. history — and those younger than 30 especially seem to be drifting from organized religion. A third of young Americans say they don't belong to any religion.

raised Jewish and considers herself Jewish with an "agnostic bent." She loves going to synagogue.

I realize maybe there's a disconnect there — why are you doing it if you don't necessarily have a belief in God? But I think there's a cultural aspect, there's a spiritual aspect, I suppose. I find the practice of sitting and being quiet and being alone with your thoughts to be helpful, but I don't think I need to answer that question [about God] in order to participate in the traditions I was brought up with."

he can't see the fans or the football field like his teammates

he long snapper for the University of Southern California is blind

fter losing his eyesight, he never dreamed that one day he would be walking on the field as a player.

Mitochondria are our cells' energy dynamos. Descended from bacteria that colonized other cells about 2 billion years, they get flaky as we age.

While it's not clear why our mitochondria fade as we age, evidence suggests that it leads to everything from heart failure to neurodegeneration,

Recent research suggests it may be possible to reverse mitochondrial decay with dietary supplements that increase cellular levels of a molecule called NAD (nicotinamide adenine dinucleotide).

As we age, our brains naturally shrink and our risk of having a stroke, dementia or Alzheimer's rise, and almost everyone experiences some kind of memory loss

Scientists know that people who exercise regularly, eat a healthy diet, avoid smoking and keep mentally stimulated generally have healthier brains

Researchers figured this out by looking at the brains of 674 people with an average age of 80. They asked these elderly people to fill out food surveys about what they ate in the last year and researchers scanned their brains. The group that ate a Mediterranean diet had heavier brains with more gray and white matter.

Mitochondria are our cells' energy dynamos. Descended from bacteria that colonized other cells about 2 billion years, they get flaky as we age. A prominent theory of aging holds that decaying of mitochondria is a key driver of aging. While it's not clear why our mitochondria fade as we age, evidence suggests that it leads to everything from heart failure to neurodegeneration, as well as the complete absence of zipping around the supper table.

t may be possible to reverse mitochondrial decay with dietary supplements that increase cellular levels of a molecule called NAD (nicotinamide adenine dinucleotide).

This time his lab made headlines by reporting that the mitochondria in muscles of elderly mice were restored to a youthful state after just a week of injections with NMN (nicotinamide mononucleotide), a molecule that naturally occurs in cells and, like NR, boosts levels of NAD.

eproducible result may actually be the rarest of birds. Replication, the ability of another lab to reproduce a finding, is the gold standard of science, reassurance that you have discovered something true

With the most accessible truths already discovered, what remains are often subtle effects, some so delicate that they can be conjured up only under ideal circumstances, using highly specialized techniques.

any hypotheses already start with a high chance of being wrong

Many books and hundreds of articles have been written about how drug companies have “gamed every system” to push their products. Negative clinical studies are suppressed; claims are made for larger usefulness that have no real basis in fact; side effects are ignored or deliberately underreported; and companies pay fines in the billions that still represent small fractions of total sales.

Spending enormous amounts of cash looking at cancer, cardiovascular and “women’s health” research, the Bayer scientists could corroborate less than a quarter of the studies they tested. In other words, 75-80% of these major research findings could not be confirmed.

Science lives on replication. Yet these clinically critical attempts to corroborate research findings could not confirm them. Why? Ironically, the reasons resemble many that are used to describe the malfeasance of drug companies – the need for money, grant support, major findings to achieve tenure – and a desire for others not to have the “secret sauce” of methodology needed to create the research.

All scientific results are, of course, subject to revision and refutation by later experiments. The problem comes when these replications don’t occur and the information keeps spreading unchecked. Continue reading the main story Related Coverage Raw Data: Hills to Scientific Discoveries Grow SteeperFEB. 17, 2014 Raw Data: New Truths That Only One Can SeeJAN. 20, 2014 D

Based on the number of papers in major journals, Dr. Ioannidis estimates that the field accounts for some 50 percent of published research.

Together that constitutes most of scientific research. The remaining slice is physical science — everything from geology and climatology to cosmology and particle physics. These fields have not received the same kind of scrutiny as the others. Is that because they are less prone to the problems Dr. Ioannides describe

“Breaking Bad” implicitly challenges audiences to get down to bedrock and actually justify those norms. Why is it so wrong to kill strangers — often dangerous strangers! — so that your own family can survive and prosper? Why is it wrong to exploit people you don’t see or care about for the sake of those inside your circle? Why is Walter White’s empire-building — carried out with boldness, brilliance and guile — not an achievement to be admired?

The allure for Team Walt is not ultimately the pull of nihilism, or the harmless thrill of rooting for a supervillain. It’s the pull of an alternative moral code, neither liberal nor Judeo-Christian, with an internal logic all its own. As James Bowman wrote in The New Atlantis, embracing Walt doesn’t requiring embracing “individual savagery” and a world without moral rules. It just requires a return to “old rules” — to “the tribal, family-oriented society and the honor culture that actually did precede the Enlightenment’s commitment to universal values.”

Those rules seem cruel by the lights of both cosmopolitanism and Christianity, but they are not irrational or necessarily false. Their Darwinian logic is clear enough, and where the show takes place — in the shadow of cancer, the shadow of death — the kindlier alternatives can seem softheaded, pointless, naïve.

The patient is feeble and near death, his bone marrow eviscerated by cancer. The supervising oncologist has ordered a course of chemotherapy using a very toxic investigational drug. Stuart knows enough to feel certain that the treatment will kill the patient, and he does not believe the patient understands this.

“I walked out of that room and said, ‘There has got to be a better way than this,’ ” he told me recently. “I was appalled by how we care for—or, more accurately, fail to care about—people who are near the end of life. We literally treat them to death.”

advocating home-based primary care, which represents a fundamental change in the way we care for people who are chronically very ill. The idea is simple: rather than wait until people get sick and need hospitalization, you build a multidisciplinary team that visits them at home,

Limbaugh is onto something. The Pope of the Catholic Church really is offering a rebuttal to the Pope of the Republican party, which is what Limbaugh has largely become. In daily encyclicals, Rush is infallible in doctrine and not to be questioned in public. When he speaks on the airwaves, it is always ex cathedra. Callers can get an audience from him, but rarely a hearing. Dissent from his eternal doctrines means excommunication from the GOP and the designation of heretic. His is always the last word.

And in the Church of Limbaugh, market capitalism is an unqualified, eternal good. It is the ever-lasting truth about human beings. It is inextricable from any concept of human freedom. The fewer restrictions on it, the better.

The church has long opposed market capitalism as the core measure of human well-being. Aquinas even taught that interest-bearing loans were inherently unjust in the most influential theological document in church history. The fundamental reason is that market capitalism measures human life by a materialist rubric. And Jesus radically taught us to give up all our possessions, to renounce everything except our “daily bread”, to spend our lives serving the poverty-stricken takers rather than aspiring to be the wealthy and powerful makers. He told the Mark Zuckerberg of his day to give everything away to the poor, if he really wanted to be happy.

I recently asked one of my youngest daughters what she feared most. She answered without hesitation: failure. This disturbed and surprised me. I had always thought of fear of failure as an adult preoccupation, but it seems that one of the effects of the climate of the times (and the media saturation that expresses it) is the importation of adult fears to childish minds. The fear of ghosts is being replaced by the terror of underperformance.

In this survey, from Johns Hopkins University in Baltimore, the top five fears 30 years ago were animals, being in a dark room, high places, strangers and loud noises. In the updated survey, kids were afraid of divorce, nuclear war, cancer, pollution, and being mugged.

Children’s fears are a litmus test of the society we live in and they are clearly changing – becoming more concrete – as society becomes more performance-driven, insecure and saturated with threatening, upsetting facts.

In a recent piece for National Geographic, Book Talk curator Simon Worrall entitled his headline, “In Age of Science, Is Religion 'Harmful Superstition'?” For the answer, he gave platform to Jerry Coyne, author of Faith vs. Fact: Why Science and Religion Are Incompatible.

Coyne, an atheist and University of Chicago professor of Ecology and Evolution, answered, among other questions, why “are religion and science incompatible.”

“[T]here are a number of things about evolution and science that undermine religion,” Coyne responded, including “the fact that the Genesis story is wrong.” “There’s no evidence that there’s any qualitatively different feature about humans from other species, except maybe for language” – language that “could have evolved via culture.”

Some questions you ask because you want the right answer. Others are valuable because no answer is right; the payoff comes from the range of attempts.

That is the diversity of views about the types of historical breakthroughs that matter, with a striking consensus on whether the long trail of innovation recorded here is now nearing its end.

The clearest example of consensus was the first item on the final compilation, the printing press

We rely on computers to fly our planes, find our cancers, design our buildings, audit our businesses. That's all well and good. But what happens when the computer fails?

On the evening of February 12, 2009, a Continental Connection commuter flight made its way through blustery weather between Newark, New Jersey, and Buffalo, New York.

The Q400 was well into its approach to the Buffalo airport, its landing gear down, its wing flaps out, when the pilot’s control yoke began to shudder noisily, a signal that the plane was losing lift and risked going into an aerodynamic stall. The autopilot disconnected, and the captain took over the controls. He reacted quickly, but he did precisely the wrong thing: he jerked back on the yoke, lifting the plane’s nose and reducing its airspeed, instead of pushing the yoke forward to gain velocity.