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Javier E

How 'The Good Place' Goes Beyond 'The Trolley Problem' - The Atlantic - 1 views

  • A sitcom may seem like an unlikely vehicle for serious discussions about moral philosophy, which viewers might expect to find in medical and legal dramas (albeit in less literal, didactic forms). But the subject and medium are surprisingly compatible. A comedy can broach otherwise tedious-sounding ideas with levity and self-awareness, and has more leeway to use contrived or exaggerated scenarios to bring concepts to life
  • bringing digestible ethics lessons to the masses can be seen as a moral act, ensuring that those who don’t spend hours poring over Kant and Judith Jarvis Thomson are also privy to what’s gained from understanding how people think.
  • The Good Place’s focus on ethics wouldn’t mean as much if it weren’t also remarkable in other ways—the performances, the top-notch writing, the wordplay and pun-laden jokes, the willingness to formally experiment with the sitcom genre.
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  • “While we’re discussing the issues that I want to discuss, I also know that I have a responsibility to the audience to tell a story. The goal is not to change the world; the goal of this is to make a high-quality, entertaining show that has good-quality acting.” On that front, Season 2 has certainly succeeded
cvanderloo

In Texas, price gouging during disasters is illegal - it is also on very shaky ethical ... - 1 views

  • In Houston, as millions suffered power and water outages, food shortages and subfreezing temperatures, another problem confronted families: price hikes.Steep increases in the price of food, gas and fuel have been reported across Texas. And as millions of Texans lost power, exorbitant prices were being asked for hotel rooms with power, with some climbing to US$1,000 a night.
  • Disaster creates a scarcity of basic necessities; retailers and providers respond by sharply raising the price tags on sought-after commodities.
  • Contrarian voices argue that price hikes are good – they provide incentives for sellers to bring extra supplies and prevent hoarding.
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  • Whether price gouging helps bring more supply to disaster victims is speculative, but a surer outcome is that it will disproportionately burden the worst-off.
  • that is, an obligation to help others in danger when doing so entails only a small cost to yourself.
    • cvanderloo
       
      duty of early rescue
  • Picture a hiker lost in the woods suffering serious dehydration. A second hiker walks by and offers to sell her his extra water, but for a large sum.This violates the duty of easy rescue because it risks failing to save someone who can easily be saved, so long as the second hiker does not need the water himself.
  • Rescuing someone with little risk or cost to yourself is a moral duty, not a duty enforced by law in the U.S. So, some people might ask, why should it be enforced on would-be price gougers?
  • We are all better off when we cooperate to provide services that at some point we all may need.
    • cvanderloo
       
      social contract theory
  • This extends to rescue services such as firefighters, paramedics and first responders. But when life-threatening conditions arise from lack of food, water, shelter and power, this burden of rescue can be delegated to sellers of necessities and providers of utilities. At the least, society requires that they not raise prices and turn away those who cannot pay.
  • But actual inequality provides a reason to enforce laws against price gouging. When prices rise, the worst-off suffer the most.
Javier E

The Surprising Challenge of Teaching Ethics in US Schools | HuffPost - 0 views

  • Should schools be teaching morals? What does it mean to be moral or ethical?
blythewallick

Are We Being Framed? | JSTOR Daily - 0 views

  • So the Mueller Report is finally out. President Trump has called it a “total exoneration,” but we don’t have to take his word for it. After special counsel Robert Mueller’s comprehensive, two-year investigation into serious allegations of Russian electoral interference, conspiracy, and obstruction of justice, we’re free to read what the special counsel’s findings actually are, if we so choose—albeit with a number of careful redactions from William Barr that along with his four-page summary, framed public conversations about the report in important ways.
  • It can persuade us one way or another by using certain rhetorical or linguistic means. What’s more, a particular framing doesn’t just arise spontaneously to the top of the public consciousness from its own legitimate merits, because it happens to be the neutral truth. We would be naive to think so, yet many people do. When it comes to the power of states, in sociologist Christopher A. Bail’s view, it has to be knowingly crafted, with two realities. One is a front stage presentation for public consumption and the other a secret collective coordination behind the scenes. Their reality becomes your reality, one way or another.
  • To Dwight Bolinger, “literal truth—the kind one swears to tell on the witness stand—permits any amount of evasion.” He explains: “The most insidious of all concepts of truth is that of literalness. The California prune-growers tell us that prunes, pound for pound, offer several times more vitamins and minerals than fresh fruit; literally true. The oil industry advertises that no heat costs less than oil heat, which has to be true because no heat costs nothing at all.” Those savvy enough to see through it will simply eat fewer prunes and heat their homes differently to those who fall for it. But declaring that you didn’t lie but told the literal truth in this way seems a kind of hollow ethic, a careful weaselling around the words that some lawyers seem particularly adept at.
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  • So, yes, it’s perhaps literally true that no collusion was found by Mueller’s team because they weren’t actually investigating collusion, but a much harder-to-prove charge of criminal conspiracy. Collusion and conspiracy may be related, but they’re not the same. Yet in the resulting media commentary, this framing by the Trump administration was largely successful in amplifying the confused conflation of two separate concepts: One is the fact that Mueller did not ultimately find definitive proof that the Trump campaign illegally conspired with Russia; The other is the non-legal Trump talking point of “no collusion,” even though not finding something is certainly not the same as there being none (at least you would hope so, if you ever can’t find your house keys or wallet).
  • One such case is Muscarello v. United States, from 1998. The law was that anyone caught using or carrying a firearm while selling drugs (presumably on their person) would get an additional five year sentence. The defendant, Muscarello, had a firearm that he was actively not carrying because it was actually locked up in the glove compartment of his truck. Nevertheless this was redefined as “carrying” a firearm, because the judge in the case saw that one of the first definitions in a dictionary for the word happen to be in relation to “carrying” (i.e. transporting) things in vehicles.
  • These are all fairly simple and obvious features of dictionaries that are frequently overlooked in legal contexts, just when it matters most that careful and ethical consideration should go into the linguistic interpretation of the law.
  • If we don’t pay enough attention to linguistic ethics, language and the truth that it seems to tell can be subtly manipulated to misdirect us. Even the most precise legal wording of a thorough report can be misread, as long as the public is willing to allow it.
Javier E

Lawyer Who Used ChatGPT Faces Penalty for Made Up Citations - The New York Times - 0 views

  • “I did not comprehend that ChatGPT could fabricate cases,” he told Judge Castel.
  • At times during the hearing, Mr. Schwartz squeezed his eyes shut and rubbed his forehead with his left hand. He stammered and his voice dropped. He repeatedly tried to explain why he did not conduct further research into the cases that ChatGPT had provided to him.
  • For nearly two hours Thursday, Mr. Schwartz was grilled by a judge in a hearing ordered after the disclosure that the lawyer had created a legal brief for a case in Federal District Court that was filled with fake judicial opinions and legal citations, all generated by ChatGPT.
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  • “I continued to be duped by ChatGPT. It’s embarrassing,” Mr. Schwartz said.
  • As Mr. Schwartz answered the judge’s questions, the reaction in the courtroom, crammed with close to 70 people who included lawyers, law students, law clerks and professors, rippled across the benches. There were gasps, giggles and sighs. Spectators grimaced, darted their eyes around, chewed on pens.
  • “This case has reverberated throughout the entire legal profession,” said David Lat, a legal commentator. “It is a little bit like looking at a car wreck.”
  • The episode, which arose in an otherwise obscure lawsuit, has riveted the tech world, where there has been a growing debate about the dangers — even an existential threat to humanity — posed by artificial intelligence. It has also transfixed lawyers and judges.
  • Avianca asked Judge Castel to dismiss the lawsuit because the statute of limitations had expired. Mr. Mata’s lawyers responded with a 10-page brief citing more than half a dozen court decisions, with names like Martinez v. Delta Air Lines, Zicherman v. Korean Air Lines and Varghese v. China Southern Airlines, in support of their argument that the suit should be allowed to proceed.After Avianca’s lawyers could not locate the cases, Judge Castel ordered Mr. Mata’s lawyers to provide copies. They submitted a compendium of decisions.It turned out the cases were not real.
  • Mr. Schwartz, who has practiced law in New York for 30 years, said in a declaration filed with the judge this week that he had learned about ChatGPT from his college-aged children and from articles, but that he had never used it professionally.He told Judge Castel on Thursday that he had believed ChatGPT had greater reach than standard databases.“I heard about this new site, which I falsely assumed was, like, a super search engine,” Mr. Schwartz said.
  • Irina Raicu, who directs the internet ethics program at Santa Clara University, said this week that the Avianca case clearly showed what critics of such models have been saying, “which is that the vast majority of people who are playing with them and using them don’t really understand what they are and how they work, and in particular what their limitations are.”
  • “This case has changed the urgency of it,” Professor Roiphe said. “There’s a sense that this is not something that we can mull over in an academic way. It’s something that has affected us right now and has to be addressed.”
  • In the declaration Mr. Schwartz filed this week, he described how he had posed questions to ChatGPT, and each time it seemed to help with genuine case citations. He attached a printout of his colloquy with the bot, which shows it tossing out words like “sure” and “certainly!”After one response, ChatGPT said cheerily, “I hope that helps!”
Javier E

Opinion | Noam Chomsky: The False Promise of ChatGPT - The New York Times - 0 views

  • we fear that the most popular and fashionable strain of A.I. — machine learning — will degrade our science and debase our ethics by incorporating into our technology a fundamentally flawed conception of language and knowledge.
  • OpenAI’s ChatGPT, Google’s Bard and Microsoft’s Sydney are marvels of machine learning. Roughly speaking, they take huge amounts of data, search for patterns in it and become increasingly proficient at generating statistically probable outputs — such as seemingly humanlike language and thought
  • if machine learning programs like ChatGPT continue to dominate the field of A.I
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  • , we know from the science of linguistics and the philosophy of knowledge that they differ profoundly from how humans reason and use language. These differences place significant limitations on what these programs can do, encoding them with ineradicable defects.
  • It is at once comic and tragic, as Borges might have noted, that so much money and attention should be concentrated on so little a thing — something so trivial when contrasted with the human mind, which by dint of language, in the words of Wilhelm von Humboldt, can make “infinite use of finite means,” creating ideas and theories with universal reach.
  • The human mind is not, like ChatGPT and its ilk, a lumbering statistical engine for pattern matching, gorging on hundreds of terabytes of data and extrapolating the most likely conversational response or most probable answer to a scientific question
  • the human mind is a surprisingly efficient and even elegant system that operates with small amounts of information; it seeks not to infer brute correlations among data points but to create explanations
  • such programs are stuck in a prehuman or nonhuman phase of cognitive evolution. Their deepest flaw is the absence of the most critical capacity of any intelligence: to say not only what is the case, what was the case and what will be the case — that’s description and prediction — but also what is not the case and what could and could not be the case
  • Those are the ingredients of explanation, the mark of true intelligence.
  • Here’s an example. Suppose you are holding an apple in your hand. Now you let the apple go. You observe the result and say, “The apple falls.” That is a description. A prediction might have been the statement “The apple will fall if I open my hand.”
  • an explanation is something more: It includes not only descriptions and predictions but also counterfactual conjectures like “Any such object would fall,” plus the additional clause “because of the force of gravity” or “because of the curvature of space-time” or whatever. That is a causal explanation: “The apple would not have fallen but for the force of gravity.” That is thinking.
  • The crux of machine learning is description and prediction; it does not posit any causal mechanisms or physical laws
  • any human-style explanation is not necessarily correct; we are fallible. But this is part of what it means to think: To be right, it must be possible to be wrong. Intelligence consists not only of creative conjectures but also of creative criticism. Human-style thought is based on possible explanations and error correction, a process that gradually limits what possibilities can be rationally considered.
  • ChatGPT and similar programs are, by design, unlimited in what they can “learn” (which is to say, memorize); they are incapable of distinguishing the possible from the impossible.
  • Whereas humans are limited in the kinds of explanations we can rationally conjecture, machine learning systems can learn both that the earth is flat and that the earth is round. They trade merely in probabilities that change over time.
  • For this reason, the predictions of machine learning systems will always be superficial and dubious.
  • some machine learning enthusiasts seem to be proud that their creations can generate correct “scientific” predictions (say, about the motion of physical bodies) without making use of explanations (involving, say, Newton’s laws of motion and universal gravitation). But this kind of prediction, even when successful, is pseudoscienc
  • While scientists certainly seek theories that have a high degree of empirical corroboration, as the philosopher Karl Popper noted, “we do not seek highly probable theories but explanations; that is to say, powerful and highly improbable theories.”
  • The theory that apples fall to earth because mass bends space-time (Einstein’s view) is highly improbable, but it actually tells you why they fall. True intelligence is demonstrated in the ability to think and express improbable but insightful things.
  • This means constraining the otherwise limitless creativity of our minds with a set of ethical principles that determines what ought and ought not to be (and of course subjecting those principles themselves to creative criticism)
  • True intelligence is also capable of moral thinking
  • To be useful, ChatGPT must be empowered to generate novel-looking output; to be acceptable to most of its users, it must steer clear of morally objectionable content
  • In 2016, for example, Microsoft’s Tay chatbot (a precursor to ChatGPT) flooded the internet with misogynistic and racist content, having been polluted by online trolls who filled it with offensive training data. How to solve the problem in the future? In the absence of a capacity to reason from moral principles, ChatGPT was crudely restricted by its programmers from contributing anything novel to controversial — that is, important — discussions. It sacrificed creativity for a kind of amorality.
  • Here, ChatGPT exhibits something like the banality of evil: plagiarism and apathy and obviation. It summarizes the standard arguments in the literature by a kind of super-autocomplete, refuses to take a stand on anything, pleads not merely ignorance but lack of intelligence and ultimately offers a “just following orders” defense, shifting responsibility to its creators.
  • In short, ChatGPT and its brethren are constitutionally unable to balance creativity with constraint. They either overgenerate (producing both truths and falsehoods, endorsing ethical and unethical decisions alike) or undergenerate (exhibiting noncommitment to any decisions and indifference to consequences). Given the amorality, faux science and linguistic incompetence of these systems, we can only laugh or cry at their popularity.
Emily Horwitz

UK, Japan scientists win Nobel for stem cell breakthroughs | Reuters - 0 views

  • Scientists from Britain and Japan shared a Nobel Prize on Monday for the discovery that adult cells can be transformed back into embryo-like stem cells that may one day regrow tissue in damaged brains, hearts or other organs.
  • discovered ways to create tissue that would act like embryonic cells, without the need to harvest embryos.
  • "These groundbreaking discoveries have completely changed our view of the development and specialization of cells," the Nobel Assembly at Stockholm's Karolinska Institute said.
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  • big hope for stem cells is that they can be used to replace damaged tissue in everything from spinal cord injuries to Parkinson's disease.
  • Scientists once thought it was impossible to turn adult tissue back into stem cells, which meant that new stem cells could only be created by harvesting embryos - a practice that raised ethical qualms in some countries and also means that implanted cells might be rejected by the body.
  • The new stem cells are known as "induced pluripotency stem cells", or iPS cells.
  • "We would like to be able to find a way of obtaining spare heart or brain cells from skin or blood cells. The important point is that the replacement cells need to be from the same individual, to avoid problems of rejection and hence of the need for immunosuppression."
  • Thomas Perlmann, Nobel Committee member and professor of Molecular Development Biology at the Karolinska Institute said: "Thanks to these two scientists, we know now that development is not strictly a one-way street."
  • "You can't take out a large part of the heart or the brain or so to study this, but now you can take a cell from for example the skin of the patient, reprogram it, return it to a pluripotent state, and then grow it in a laboratory," he said.
Sean Kirkpatrick

Ethics and Politics : Joseph Roblat - 1 views

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    Ethics and Politics Discussion by Joseph Roblat
Javier E

Can Just Anyone Claim to Be a TV Meteorologist? - NYTimes.com - 0 views

  • Does an individual have the right to professionally define who she is, or is that designation dictated by other people? Is there an ethical responsibility to describe oneself in a standardized, universally accepted context?
  • Most titles are self-applied. This is generally fine, because most titles are meaningless. If you declare yourself a futurist or a farmer or a musician (or an ethicist), that’s what you are, even if reasonable people can disagree. Most titles indicate only intent (“I call myself a ____ because that is what I aspire to do”). Failure to fulfill that intent has no significant impact on other people; as such, ethics aren’t really in play
  • But this is not the case for those rarefied professions in which strangers rely on someone they’ve never met to possess essential, functional, nonnegotiable knowledge that no normal person could attain without intense schooling or specialized experience. I would place neurosurgeon near the top of this tier.
Sean Kirkpatrick

What are values? - 1 views

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    I specifically bookmarked this article because I believe that ones personal values can depend a lot on their opinion of what is ethical, etc. This is why I believe that the word values and ethics are both extremely hard to define because I believe that they mean different things to all different people.
Javier E

Adam Kirsch: Art Over Biology | The New Republic - 1 views

  • Nietzsche, who wrote in Human, All Too Human, under the rubric “Art dangerous for the artist,” about the particular ill-suitedness of the artist to flourishing in a modern scientific age: When art seizes an individual powerfully, it draws him back to the views of those times when art flowered most vigorously.... The artist comes more and more to revere sudden excitements, believes in gods and demons, imbues nature with a soul, hates science, becomes unchangeable in his moods like the men of antiquity, and desires the overthrow of all conditions that are not favorable to art.... Thus between him and the other men of his period who are the same age a vehement antagonism is finally generated, and a sad end
  • What is modern is the sense of the superiority of the artist’s inferiority, which is only possible when the artist and the intellectual come to see the values of ordinary life—prosperity, family, worldly success, and happiness—as inherently contemptible.
  • Art, according to a modern understanding that has not wholly vanished today, is meant to be a criticism of life, especially of life in a materialist, positivist civilization such as our own. If this means the artist does not share in civilization’s boons, then his suffering will be a badge of honor.
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  • The iron law of Darwinian evolution is that everything that exists strives with all its power to reproduce, to extend life into the future, and that every feature of every creature can be explained as an adaptation toward this end. For the artist to deny any connection with the enterprise of life, then, is to assert his freedom from this universal imperative; to reclaim negatively the autonomy that evolution seems to deny to human beings. It is only because we can freely choose our own ends that we can decide not to live for life, but for some other value that we posit. The artist’s decision to produce spiritual offspring rather than physical ones is thus allied to the monk’s celibacy and the warrior’s death for his country, as gestures that deny the empire of mere life.
  • Animals produce beauty on their bodies; humans can also produce it in their artifacts. The natural inference, then, would be that art is a human form of sexual display, a way for males to impress females with spectacularly redundant creations.
  • For Darwin, the human sense of beauty was not different in kind from the bird’s.
  • Still, Darwin recognized that the human sense of beauty was mediated by “complex ideas and trains of thought,” which make it impossible to explain in terms as straightforward as a bird’s:
  • Put more positively, one might say that any given work of art can be discussed critically and historically, but not deduced from the laws of evolution.
  • with the rise of evolutionary psychology, it was only a matter of time before the attempt was made to explain art in Darwinian terms. After all, if ethics and politics can be explained by game theory and reciprocal altruism, there is no reason why aesthetics should be different: in each case, what appears to be a realm of human autonomy can be reduced to the covert expression of biological imperatives
  • Still, there is an unmistakable sense in discussions of Darwinian aesthetics that by linking art to fitness, we can secure it against charges of irrelevance or frivolousness—that mattering to reproduction is what makes art, or anything, really matter.
  • The first popular effort in this direction was the late Denis Dutton’s much-discussed book The Art Instinct, which appeared in 2009.
  • Dutton’s Darwinism was aesthetically conservative: “Darwinian aesthetics,” he wrote, “can restore the vital place of beauty, skill, and pleasure as high artistic values.” Dutton’s argument has recently been reiterated and refined by a number of new books,
  • “The universality of art and artistic behaviors, their spontaneous appearance everywhere across the globe ... and the fact that in most cases they can be easily recognized as artistic across cultures suggest that they derive from a natural, innate source: a universal human psychology.”
  • Again like language, art is universal in the sense that any local expression of it can be “learned” by anyone.
  • Yet earlier theorists of evolution were reluctant to say that art was an evolutionary adaptation like language, for the simple reason that it does not appear to be evolutionarily adaptive.
  • Stephen Jay Gould suggested that art was not an evolutionary adaptation but what he called a “spandrel”—that is, a showy but accidental by-product of other adaptations that were truly functiona
  • the very words “success” and “failure,” despite themselves, bring an emotive and ethical dimension into the discussion, so impossible is it for human beings to inhabit a valueless world. In the nineteenth century, the idea that fitness for survival was a positive good motivated social Darwinism and eugenics. Proponents of these ideas thought that in some way they were serving progress by promoting the flourishing of the human race, when the basic premise of Darwinism is that there is no such thing as progress or regress, only differential rates of reproduction
  • In particular, Darwin suggests that it is impossible to explain the history or the conventions of any art by the general imperatives of evolution
  • Boyd begins with the premise that human beings are pattern-seeking animals: both our physical perceptions and our social interactions are determined by our brain’s innate need to find and to
  • Art, then, can be defined as the calisthenics of pattern-finding. “Just as animal physical play refines performance, flexibility, and efficiency in key behaviors,” Boyd writes, “so human art refines our performance in our key perceptual and cognitive modes, in sight (the visual arts), sound (music), and social cognition (story). These three modes of art, I propose, are adaptations ... they show evidence of special design in humans, design that offers survival and especially reproductive advantages.”
  • make coherent patterns
Javier E

Trump's personality will help us learn how our minds work | Deborah Orr | Opinion | The... - 0 views

  • Many observers saw quite quickly that Trump’s personality was highly disordered.
  • The opportunity for everyone to learn a lot about this domineering, exploitative, unstable and superficially charismatic personality type has presented itself on a grand scale.
  • All the neuroimaging, all the psychological theorising, all the psychiatric experimentation with pharmacology, it’s already prompting a huge need for careful, scientifically anchored engagement with the ethical and philosophical debate about what it is to be human.
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  • The idea that every human brain is mechanically perfect – with cruel or annihilating impulses somehow separate from it, as if repugnant thoughts were like stagnant water running through an infallibly reliable plumbing system – is silly but somehow comforting.
  • our potential for understanding that it’s all in our minds, and working out how individual minds can develop in a well-adjusted way, has never been greater. That, to me, gives great hope for the future.
sissij

New Prospects for Growing Human Replacement Organs in Animals - The New York Times - 0 views

  • For the first time, biologists have succeeded in growing human stem cells in pig embryos, shifting from science fiction to the realm of the possible the idea of developing human organs in animals for later transplant.
  • Since the organ would be made of a patient’s own cells, there would be little risk of immune rejection.
  • They would be generated by implanting human stem cells into an early pig embryo, resulting in an animal composed of mixed pig and human cells.
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  • The two reports together establish the feasibility of trying to grow replacement human organs in animals, though such a goal is still far off.
  • Creating chimeras, especially those with human cells, may prove controversial, given the possibility that test animals could be humanized in undesirable ways. One would be if human cells should be incorporated into a pig’s brain, endowing it with human qualities. Almost no one wants a talking pig.
  • The ban is still in place, and it’s unclear whether the Trump administration would continue to consider lifting the moratorium or whether new objections would be raised to using public funds for this line of research.
  • But no one knows exactly what sequence of chemicals is required for the generation of each different tissue or organ. This may be why glassware experiments with stem cells have not yet lived up to their full promise.
  • Concern about human cells’ incorporation into a lower animal’s brain is not without basis. Dr. Steven Goldman of the University of Rochester Medical Center found in 2013 that mice injected with a special type of human brain cell had enhanced learning abilities.
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    The ethics in biology is always a controversial issue in the research. In biology, we want to get as close to the truth as we possibly can, but that sometimes means that we have to research on things that are considered to be inhumane. This article talks about a new possibility that we can grow human stem cells in animals. That would lead to a potential problem of animals gaining intelligence. If animals start to have human properties, how would we treat them? Will they be a threat to our identity? And also, through the experiment described in the article, we can see that the scientific method in biology is dealing with probabilism and population. It is always gathering data. They are always ready for exceptions. --Sissi (1/28/2017)
Ellie McGinnis

The Mammoth Cometh - NYTimes.com - 2 views

  • Brand helped to establish in 1996 to support projects designed to inspire “long-term responsibility.”
  • The theme of the talk was “Is Mass Extinction of Life on Earth Inevitable?”
  • the resurrection of extinct species, like the woolly mammoth, aided by new genomic technologies developed by the Harvard molecular biologist George Church.
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  • Just as the loss of a species decreases the richness of an ecosystem, the addition of new animals could achieve the opposite effect.
  • National Geographic Society hosted a larger conference to debate the scientific and ethical questions raised by the prospect of “de-extinction.
  • “De-extinction went from concept to potential reality right before our eyes,
  • “This may be the biggest attraction and possibly the biggest benefit of de-extinction. It would surely be very cool to see a living woolly mammoth.”
  • less scientific, if more persuasive, argument was advanced by the ethicist Hank Greely and the law professor Jacob Sherkow, both of Stanford. De-extinction should be pursued, they argued in a paper published in Science, because it would be really
  • They will replace chunks of band-tailed-pigeon DNA with synthesized chunks of passenger-pigeon DNA, until the cell’s genome matches their working passenger-pigeon genome.
  • Scientists predict that changes made by human beings to the composition of the atmosphere could kill off a quarter of the planet’s mammal species, a fifth of its reptiles and a sixth of its birds by 2050
  • This cloning method, called somatic cell nuclear transfer, can be used only on species for which we have cellular material.
  • There is a shortcut. The genome of a closely related species will have a high proportion of identical DNA, so it can serve as a blueprint, or “scaffold.”
  • By comparing the fragments of passenger-pigeon DNA with the genomes of similar species, researchers can assemble an approximation of an actual passenger-pigeon genome.
  • “We’ve framed it in terms of conservation,”
  • the genome will have to be inscribed into a living cell.
  • As with any translation, there may be errors of grammar, clumsy phrases and perhaps a few missing passages, but the book will be legible. It should, at least, tell a good story.
  • MAGE (Multiplex Automated Genome Engineering). MAGE is nicknamed the “evolution machine” because it can introduce the equivalent of millions of years of genetic mutations within minutes
  • Developmental and behavioral biologists would take over, just in time to answer some difficult questions. Chicks imitate their parents’ behavior. How do you raise a passenger pigeon without parents of its own species? And how do you train band-tailed pigeons to nurture the strange spawn that emerge from their eggs; chicks that, to them, might seem monstrous: an avian Rosemary’s Baby?
  • For endangered species with tiny populations, scientists would introduce genetic diversity to offset inbreeding.
  • They will try to alter the birds’ diets, migration habits and environment. The behavior of each subsequent generation will more closely resemble that of their genetic cousins.
  • “There’s always this fear that somehow, if we do it, we’re going to accidentally make something horrible, because only nature can really do it right. But nature is totally random. Nature makes monsters. Nature makes threats. Many of the things that are most threatening to us are a product of nature. Revive & Restore is not going to tip the balance in any way.”
  • For species threatened by contagion, an effort would be made to fortify their DNA with genes that make them disease-resistant
  • This optimistic, soft-focus fantasy of de-extinction, while thrilling to Ben Novak, is disturbing to many conservation biologists, who consider it a threat to their entire discipline and even to the environmental movement.
  • The first question posed by conservationists addresses the logic of bringing back an animal whose native habitat has disappeared. Why go through all the trouble just to have the animal go extinct all over again?
  • There is also anxiety about disease
  • “If you recreate a species genetically and release it, and that genotype is based on a bird from a 100-year-old environment, you probably will increase risk.”
  • The scientific term for this type of genetic intervention is “facilitated adaptation.”
  • De-extinction also poses a rhetorical threat to conservation biologists. The specter of extinction has been the conservation movement’s most powerful argument. What if extinction begins to be seen as a temporary inconvenience?
  • De-extinction suggests that we can technofix our way out of environmental issues generally, and that’s very, very bad.
  • How will we decide which species to resurrect?
  • Philip Seddon recently published a 10-point checklist to determine the suitability of any species for revival, taking into account causes of its extinction, possible threats it might face upon resurrection and man’s ability to destroy the species “in the event of unacceptable ecological or socioeconomic impacts.”
  • But the most visceral argument against de-extinction is animal cruelty.
  • “Is it fair to do this to these animals?” Shapiro asked. “Is ‘because we feel guilty’ a good-enough reason?” Stewart Brand made a utilitarian counterargument: “We’re going to go through some suffering, because you try a lot of times, and you get ones that don’t take. On the other hand, if you can bring bucardos back, then how many would get to live that would not have gotten to live?”
  • In “How to Permit Your Mammoth,” published in The Stanford Environmental Law Journal, Norman F. Carlin asks whether revived species should be protected by the Endangered Species Act or regulated as a genetically modified organism.
  • He concludes that revived species, “as products of human ingenuity,” should be eligible for patenting.
  • The term “de-extinction” is misleading. Passenger pigeons will not rise from the grave
  • Our understanding of the passenger pigeon’s behavior derives entirely from historical accounts.
  • There is no authoritative definition of “species.” The most widely accepted definition describes a group of organisms that can procreate with one another and produce fertile offspring, but there are many exceptions.
  • Theseus’ ship, therefore, “became a standing example among the philosophers . . . one side holding that the ship remained the same, and the other contending that it was not the same.”
  • What is coming will go well beyond the resurrection of extinct species. For millenniums, we have customized our environment, our vegetables and our animals, through breeding, fertilization and pollination. Synthetic biology offers far more sophisticated tools. The creation of novel organisms, like new animals, plants and bacteria, will transform human medicine, agriculture, energy production and much else.
Javier E

The Two Contradictory Ideas Many Americans Have About the Economy - The Atlantic - 0 views

  • How do people reconcile a belief in individual autonomy with nationwide wage stagnation?
  • “Many middle-class wage earners are victims of the economy, and, perhaps, of that great, glowing, irresistible American promise that has been drummed into our heads since birth: Just work hard and you can have it all.”
  • This sentiment taunts at two sacred and quintessentially American convictions—that success is self-determined and that advancement is inevitable for anyone with a serious work ethic. According to a 2014 Pew Global Attitudes Study, people in the United States are much more likely to hold these two beliefs than many of their European counterparts.
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  • Many Americans, then, are holding two contradictory ideas in their mind at once: the optimistic belief that their success is in their hands (on display since Tocqueville’s Democracy in America) and the acknowledgement that wages have been steadily stagnating (on decline since the band America).
  • In his story, Gabler concedes that, no matter how illogical and uninformed his financial decisions might have been, he remained seduced by a superseding assumption that he “would always overcome any adversity, should it arrive.”
  • “This is the genius and the Achilles’ heel of American culture,” Newman says. “We do have a strong belief in self-determination and agency, even when our expectations fly in the face of reality.”
  • Struggling white-collar workers and managers, she says, especially stood out in her research for how likely they were to believe they were the authors of their own fate. “And if your destiny isn’t working out very well,” she says, “you only have yourself to blame,” in their telling.
  • part of what makes financial fragility so distressing in the United States is that citizens aren’t afforded the regimen of protections offered by Europe’s wealthier governments.
  • “These are social democracies that come to the rescue of people in trouble or are just more generous even if they’re not in trouble,” says Newman. “So the kind of suffering that will happen in a society like that is not one of material deprivation nearly as much as what we call in the trade ‘social exclusion.’”
sissij

The Stem-Cell Revolution Is Coming - Slowly - The New York Times - 3 views

  • In 2001, President George W. Bush issued an executive order banning federal funding for new sources of stem cells developed from preimplantation human embryos. The action stalled research and discouraged scientists.
  • re-energized the field by devising a technique to “reprogram” any adult cell, such as a skin cell, and coax it back to its earliest “pluripotent” stage. From there it can become any type of cell, from a heart muscle cell to a neuron.
  • But it’s a double-edged sword. After multiple cell cycles, the chances of mutations increases.
  •  
    In Biology, we learned that the study for stem cells has been halted because of the ethic issues on whether embryos should be count as human life. Now, there is this new technique that can induce skin cello its earliest "pluripotent" stage. With this technique,the study of stem cells and continue and flourish to benefit patients who need to have new cells that aren't mutated. It's surprised to see that how fast science is progressing. The science wielder at school might not be the science up to date.--Sissi (1/17/2017)
nataliedepaulo1

Who's watching Trump's ethics watchdogs? - POLITICO - 0 views

  • The lawyers tasked with policing Donald Trump’s potential conflicts of interest are grappling with an oversight system that’s disjointed and ineffective -- and one they say is mostly unnecessary.
  • The only thing you leave this world with is your reputation,” he said. “I’m very concerned about my reputation. But I’m also committed to making sure I can do it in the right way. I’m confident I can do it in a way that doesn’t diminish my reputation or the reputation of the president.”
kortanekev

Scientists Build New Computer Made of DNA - 0 views

  • Scientists at the University of Manchester have developed a new type of self-replicating computer that uses DNA to make calculations, a breakthrough that could make computing far more efficient.
  •  
    what are the ethical implications of a computer that functions much like we do... but better? Could a "DNA computer" program its own mutations? When computers do everything for us...what will be the pursuit of knowledge?  Evie K 3/4/17
Javier E

Are We Ready for a 'Morality Pill'? - NYTimes.com - 0 views

  • It seems plausible that humans, like rats, are spread along a continuum of readiness to help others. There has been considerable research on abnormal people, like psychopaths, but we need to know more about relatively stable differences (perhaps rooted in our genes) in the great majority of people as well.
  • Undoubtedly, situational factors can make a huge difference, and perhaps moral beliefs do as well, but if humans are just different in their predispositions to act morally, we also need to know more about these differences. Only then will we gain a proper understanding of our moral behavior
  • If continuing brain research does in fact show biochemical differences between the brains of those who help others and the brains of those who do not, could this lead to a “morality pill” — a drug that makes us more likely to help?
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  • many argued that we could never be justified in depriving someone of his free will, no matter how gruesome the violence that would thereby be prevented. No doubt any proposal to develop a morality pill would encounter the same objection.
  • If so, would people choose to take it? Could criminals be given the option, as an alternative to prison, of a drug-releasing implant that would make them less likely to harm others?
  • But if our brain’s chemistry does affect our moral behavior, the question of whether that balance is set in a natural way or by medical intervention will make no difference in how freely we act. If there are already biochemical differences between us that can be used to predict how ethically we will act, then either such differences are compatible with free will, or they are evidence that at least as far as some of our ethical actions are concerned, none of us have ever had free will anyway.
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