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markfrankel18

Acupuncture Doesn't Work « Science-Based Medicine - 0 views

  • Clinical research can never prove that an intervention has an effect size of zero. Rather, clinical research assumes the null hypothesis, that the treatment does not work, and the burden of proof lies with demonstrating adequate evidence to reject the null hypothesis. So, when being technical, researchers will conclude that a negative study “fails to reject the null hypothesis.” Further, negative studies do not demonstrate an effect size of zero, but rather that any possible effect is likely to be smaller than the power of existing research to detect. The greater the number and power of such studies, however, the closer this remaining possible effect size gets to zero. At some point the remaining possible effect becomes clinically insignificant. In other words, clinical research may not be able to detect the difference between zero effect and a tiny effect, but at some point it becomes irrelevant. What David and I have convincingly argued, in my opinion, is that after decades of research and more than 3000 trials, acupuncture researchers have failed to reject the null hypothesis, and any remaining possible specific effect from acupuncture is so tiny as to be clinically insignificant.
  • It is clear from meta-analyses that results of acupuncture trials are variable and inconsistent, even for single conditions. After thousands of trials of acupuncture and hundreds of systematic reviews,18 arguments continue unabated. In 2011,Pain published an editorial31 that summed up the present situation well. “Is there really any need for more studies? Ernst et al.18 point out that the positive studies conclude that acupuncture relieves pain in some conditions but not in other very similar conditions. What would you think if a new pain pill was shown to relieve musculoskeletal pain in the arms but not in the legs? The most parsimonious explanation is that the positive studies are false positives. In his seminal article on why most published research findings are false, Ioannidis32 points out that when a popular but ineffective treatment is studied, false positive results are common for multiple reasons, including bias and low prior probability.” Since it has proved impossible to find consistent evidence after more than 3000 trials, it is time to give up. It seems very unlikely that the money that it would cost to do another 3000 trials would be well-spent.
markfrankel18

The Real Miracle of Acupuncture: That Anyone Still Believes In It | Big Think - 0 views

  • It is often alleged that acupuncture is an ancient medical practice that has been refined and revered for thousands of years. In reality acupuncture is indeed an ancient medical practice, but it has in fact been in decline for thousands of years. In 1822 it was actually banned from the Imperial Medical Academy by Emperor Dao Guang. It wasn’t until 1966 that it was revived by Chairman Mao Zedong, but even he didn’t actually believe in it.
  • “Almost all trials of alternative medicines seem to end up with the conclusion that more research is needed. After more than 3,000 trials, that is dubious. ... Since it has proved impossible to find consistent evidence after more than 3,000 trials, it is time to give up.” — David Colquhoun
markfrankel18

Acupuncture Is Sham Medicine - But Has It Led Researchers to a Chronic Pain Treatment? ... - 0 views

  • One of the more benign aspects of Chinese medicine is acupuncture, a practice deemed superstitious in China in the 17th century until Mao Zedong reemployed it for political purposes in the fifties. Two decades later it infiltrated the American imagination. A myth was reborn. As Jeneen Interlandi writes, research results have been murky at best—one 2013 report of over 3,000 studies showed acupuncture to be no more effective than placebos.
markfrankel18

Do You Believe In Magic? Interview with Dr. Paul Offit - CSI - 0 views

  • I think there is something to be said for the placebo response, which is unfortunately named. I think when people hear the word “placebo,” they assume that it's dismissive, trivializing, that it's just all in my head and that it's not real. I think that in fact, the placebo response can be a physiological response. I think believing that you are about to be helped in some way goes a long way to being helped in some way.
  • If you believe that human anatomy has nothing to do with rivers in China or days of the year, then there's nothing accurate about acupuncture. Indeed, if you look at people who benefit from acupuncture, it doesn't matter where you put the needles. In fact, it doesn't even matter whether you put the needles under the skin! Even these retractable needles seem to work, so‑called “acupressure.” That is interesting!
markfrankel18

Placebo-philes - Anxious Machine - 1 views

  • It's easy to sneer at the placebo effect, or to feel ashamed of it when you're its victim. And that's precisely why I found Felix Salmon's piece revelatory, because instead of sneering at the placebo effect of fancy wine, its marketing, and its slightly higher prices, he thinks we should take advantage of it. If the placebo effect makes us happy, why not take advantage of that happiness?
  • n a recent article for the Atlantic, David H. Freedman argues that there's virtually no scientific evidence that alternative medicine (anything from chiropractic care to acupuncture) has any curative benefit beyond a placebo effect. And so many scientists are outraged that anyone takes alternative medicine seriously. However, there is one area where alternative medicine often trumps traditional medicine: stress reduction. And stress reduction can, of course, make a huge impact on people's health. The Atlantic article quotes Elizabeth Blackburn, a biologist at the University of California at San Francisco and a Nobel laureate. “We tend to forget how powerful an organ the brain is in our biology,” Blackburn told me. “It’s the big controller. We’re seeing that the brain pokes its nose into a lot of the processes involved in these chronic diseases. It’s not that you can wish these diseases away, but it seems we can prevent and slow their onset with stress management.” Numerous studies have found that stress impairs the immune system, and a recent study found that relieving stress even seems to be linked to slowing the progression of cancer in some patients. Perhaps not surprisingly, a trip to the chiropractor or the acupuncturist is much more likely to reduce your stress than a trip to the doctor. If anything, a trip to the doctor makes you more anxious.
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