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Tiberius Brastaviceanu

Open Source 3-D Printed Nutating Mixer - Appropedia, the sustainability wiki - 0 views

www.appropedia.org/rce_3-D_Printed_Nutating_Mixer

open science open hardware OSH catalog

shared by Tiberius Brastaviceanu on 10 Oct 23 - No Cached
  • Tiberius Brastaviceanu on 10 Oct 23
     
    "As the open source development of additive manufacturing has led to low-cost desktop three-dimensional (3-D) printing, a number of scientists throughout the world have begun to share digital designs of free and open source scientific hardware. Open source scientific hardware enables custom experimentation, laboratory control, rapid upgrading, transparent maintenance, and lower costs in general. To aid in this trend, this study describes the development, design, assembly, and operation of a 3-D printable open source desktop nutating mixer, which provides a fixed 20° platform tilt angle for a gentle three-dimensional (gyrating) agitation of chemical or biological samples (e.g., DNA or blood samples) without foam formation. The custom components for the nutating mixer are designed using open source FreeCAD software to enable customization. All of the non-readily available components can be fabricated with a low-cost RepRap 3-D printer using an open source software tool chain from common thermoplastics. All of the designs are open sourced and can be configured to add more functionality to the equipment in the future. It is relatively easy to assemble and is accessible to both the science education of younger students as well as state-of-the-art research laboratories. Overall, the open source nutating mixer can be fabricated with US$37 in parts, which is 1/10th of the cost of proprietary nutating mixers with similar capabilities. The open source nature of the device allow it to be easily repaired or upgraded with digital files, as well as to accommodate custom sample sizes and mixing velocities with minimal additional costs."
Francois Bergeron

Cell Tester Opens the Window of Discovery | Product Information | Articles - 0 views

www.wpiinc.com/...window.html

company physiology cell tester tools sensor

shared by Francois Bergeron on 17 Oct 12 - No Cached
  • Written by Lisa J Fulghum    Physiologic Mechanisms in Cardiac Myocytes and Skeletal Muscle Cells The revolutionary Cell Tester SI-CTS200 is a new research tool for cellular investiga
  • The revolutionary Cell Tester SI-CTS200 is a new research tool for cellular investigation that can (without any changes) be used for one single living cell, for a small multi-cellular preparation and for single or larger skinned muscle strip preparations. Translational experiments from the single living cells to the intact multi-cellular level can be accomplished.
  • The Cell Tester offers: Integral microtweezer apparatus that facilitates cellular attachment Two integrated piezo manipulators are included Bio-compatible adhesive (MyoTak™) included Unique rotational stage that allows for easy cellular alignment, improved experimental throughput (shown in the image above) Ultra-quiet force transducer included Linear displacement motor stretches or compresses cells with 25nm precision Fits ANY inverted microscope Use native cuvette or ANY 35mm glass bottom dish
  • Francois Bergeron on 17 Oct 12
     
    The revolutionary Cell Tester SI-CTS200 is a new research tool
Tiberius Brastaviceanu

Innovation Canada: A Call to Action - Review of Federal Support to Research and Develop... - 1 views

rd-review.ca/...00288.html

Industry Canada

shared by Tiberius Brastaviceanu on 04 Feb 14 - No Cached
  • Canada has a solid foundation on which to build success as a leader in the knowledge economy of tomorrow
  • innovation in Canada lags behind other highly developed countries
  • innovation is the ultimate source of the long-term competitiveness of businesses and the quality of life of Canadians
  • ...28 more annotations...
  • We heard that the government should be more focussed on helping innovative firms to grow and, particularly, on serving the needs of small and medium-sized enterprises (SMEs)
  • greater cooperation with provincial programs
  • innovation support is too narrowly focussed on R&D – more support is needed for other activities along the continuum from ideas to commercially useful innovation
  • more productive and internationally competitive economy
  • whole-of-government program delivery vehicle – the Industrial Research and Innovation Council (IRIC)
  • SR&ED program should be simplified
  • includes non-labour costs, such as materials and capital equipment, the calculation of which can be highly complex
  • the base for the tax credit should be labour-related costs, and the tax credit rate should be adjusted upward
  • fund direct support measures for SMEs
  • promoting the growth of firms
  • facilitating access by such firms to an increased supply of risk capital at both the start-up and later stages of their growth.
  • building public–private research collaborations
  • National Research Council (NRC) should become independent collaborative research organizations
  • become affiliates of universities
  • create opportunity and demand for leading-edge goods
  • encouragement of innovation in the Canadian economy should become a stated objective of procurement policies and programs.
  • the government needs to establish business innovation as a whole-of-government priority
  • put innovation at the centre of the government's economic strategy
  • Innovation Advisory Committee (IAC) – a body with a whole-of-government focus that would oversee the realization of our proposed action plan, as well as serve as a permanent mechanism to promote the refinement and improvement of the government's business innovation programs going forward.
  • focus resources where market forces are unlikely to operate effectively or efficiently and, in that context, address the full range of business innovation activities, including research, development, commercialization and collaboration with other key actors in the innovation ecosystem
  • the closer the activity being supported is to market, and therefore the more likely it is that the recipient firm will capture most of the benefit for itself.
  • specific sectors
  • of strategic importance
  • concentrated in particular regions
  • succeed in the arena of global competition
    • Tiberius Brastaviceanu
      Tiberius Brastaviceanu on 05 Feb 14
       
      They don't go beyond the firm
    • Tiberius Brastaviceanu
      Tiberius Brastaviceanu on 05 Feb 14
       
      they are still stuck in the competitive paradigm
    • Tiberius Brastaviceanu
      Tiberius Brastaviceanu on 05 Feb 14
       
      Still stack with the old paradigm of the "knowledge economy"  http://en.wikipedia.org/wiki/Knowledge_economy  My opinion is that we're moving into a know-how economy. 
sebastianklemm

Crypto4Good - 2 views

www.crypto4good.co

greens_for_good funding platform trading

shared by sebastianklemm on 25 Jun 21 - No Cached
  • sebastianklemm on 25 Jun 21
     
    Crypto4Good is a French NGO organizing charity events supported by the French-speaking crypto community. Best Practice: During a 24 hours live event by Crypto4Good + Binance Charity on 19 June 2021, two professional trading teams - Kryll.io & Diabolo.io - leveraged an experimental fund that was collected throughout the French crypto community in the weeks before the event. The two trading teams competed to make the most out of this fund within 24 hours of trading. Finally, both the money fundraised as well as the money sucessfully traded by Kryll.io & Diabolo.io will be given to NGOs in France. In the next weeks the event teams will travel to 5 cities in France: Lille, Paris, Lyon, Nantes, Toulouse, and use all of the donations collected and the money traded to buy as much food and basic necessities as possible. All these products will be donated to social services: https://www.binance.charity/fight-hunger-worldwide
Tiberius Brastaviceanu

Fostering creativity. A model for developing a culture of collective creativity in science - 0 views

www.ncbi.nlm.nih.gov/...PMC1808036

open science paper

shared by Tiberius Brastaviceanu on 05 Aug 14 - No Cached
  • Scientific progress depends on both conceptual and technological advances, which in turn depend on the creativity of scientists
  • creative processes behind these discoveries rely on mechanisms that are similar across disciplines as diverse as art and science
  • research into the nature of creativity indicates that it depends strongly on the cultural environment
  • ...48 more annotations...
  • create optimal conditions in a research organization with the aim of enhancing the creativity of its scientific staff
  • Creativity has been traditionally associated with art and literature but since the early twentieth century, science has also been regarded as a creative activity
  • Measuring creativity is a challenging task owing to its complex and elusive nature
  • Measurement of brain activity showed that creativity correlates with two brain states: a quiescent, relaxed state corresponding to the inspiration stage, and a much more active state corresponding to the elaboration stage
  • models of creativity
  • have a common feature: they depend on a balance between analytical and synthetic thinking, and usually describe the creative process as a sequence of phases that alternate between these states
  • Most research on creativity has focused on the individual
  • However, more recent studies suggest that creativity also depends strongly on the social and cultural context
  • breakthroughs depended on collaboration and social support
  • social environment in business organizations affects the creativity of their employees
  • Although creative individuals are essential, the strong link with the environment indicates that creativity might be greatly enhanced by generating a culture that supports the creative process.
  • Many of the interviewees repeatedly emphasized three main qualities necessary to be a good scientist: rigorous intellect, the ability to get the job done and the ability to have creative ideas.
  • almost all interviewees characterized their breakthrough moment as an abrupt leap in understanding
  • Although breakthroughs in science depend on such an ‘internal' conceptual shift, they also rely on ‘external' experimental results. However, most interviewees described their breakthroughs as largely internal:
  • Only two scientists expressed the view that their breakthroughs were purely external events, based on the observation of novel data.
  • intuition
  • must be combined with rational thinking to be effective
  • Although the synthesis of a new concept relies on intuition, which is based on subconscious mental processing, it must be subjected to conscious examination and analysis
  • specific mental skills or attitudes
  • ability to make unexpected connections
  • ability to choose relevant possibilities from an infinite set of irrelevant ones
  • interest in the unknown'
  • enjoyment of the creative process
  • stimulation by interacting with colleagues
  • undoubtedly the most crucial trait for creativity, which thrives on the exchange of ideas
  • The majority felt that the individual and the collective are equally important:
  • what interactions are optimal for creativity
  • The majority of interviewees answered that other people provided them with ‘inspiration to do something new'
  • positive feedback after the emergence of a new idea is almost as important as the inspiration that triggered it
  • collective provides the individual with technical expertise
  • Therefore, scientists would value a culture of interaction and mutual inspiration more highly than access to technology, although the latter is essential for their experiments.
  • At the end of the interviews, each scientist was asked to describe the best possible conditions for generating creativity at a research institute.
  • Cross-fertilization is absolutely essential
  • These results indicate strongly that an interactive environment is the single most important factor for stimulating creativity
  • interacting with people doing very different things
  • interacting with colleagues informally
  • interactions within any institution are strongly affected by its organization
  • Several interviewees described ‘an open hierarchy' as an important factor for creativity
  • hierarchy is based on genuine respect because people are great scientists, but at the same time they're very approachable and open towards what you have to say
  • These results suggest that the best conditions for scientific creativity come with a free-flowing hierarchy and a highly developed culture of interaction to guarantee the exchange of ideas and inspiration.
  • Furthermore, interdisciplinary interactions lead to the generation of new and unusual ideas
  • Finally, because of the freedom to try new things, these ideas can be tested and eventually generate new insights.
  • Creativity can be described as an emergent phenomenon
  • nonlinear phenomena
  • Emergence depends on dynamic interactions between individual agents within the system
  • The importance of a ‘freedom to try new things' and a ‘free-flowing hierarchy' further supports the idea that individual components in an emergent system must be able to interact flexibly without central control
  • During the interviews, it became apparent that although a culture of interaction and creativity exists at EMBL, this itself is not often the subject of discussion. The values on which this culture is based are seemingly implicit rather than explicit
  • Potentially, the EMBL culture of interaction could be strengthened further by consciously expressing and discussing the values on which it is based
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