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The aims of clinical and translational research are to achieve a better understanding of the pathogenesis of human disease in order to develop effective diagnostic, therapeutic and prevention strategies. Biomedical informatics can play an important role in supporting this research by facilitating the management, integration, analysis and exchange of data derived from and related to the research problems being studied. A key aspect of this support is to bring clarity, rigor and formalism to the representation of 1. disease initiation, progression, pathogenesis, signs, symptoms, assessments, clinical and laboratory findings, disease diagnosis, treatment, treatment response and outcome, and 2. the interrelations between these distinct entities both in patient management and in clinical research, thus allowing the data to be more readily retrievable and shareable, and more able to serve in the support of algorithmic reasoning.

Welcome to the National Center for Biomedical Ontology's BioPortal. BioPortal is a Web-based application for accessing and sharing biomedical ontologies. New features in BioPortal 2.0 include: * Full ontology navigation using Flash visualization * Web-service access to BioPortal content and capabilities, which enables developers to use our BioPortal services in their tools. * Ability to add Marginal Notes to classes in BioPortal ontologies, a feature that enables the community to comment on ontologies and to discuss their contents * Ability to create Point to Point Mappings between concepts in different BioPortal ontologies * Bulk export of ontology-to-ontology mappings in RDF format * Navigation of multiple ontologies, which enables users to have several ontologies opened simultaneously in different tabs in the user interface * URIs for all ontology content, which enable developers to access and share BioPortal content from their applications * Improved support through Protégé for ontologies in OWL format

NCBO Seminar Series talks occur via the Web and teleconference at 10:00AM, Pacific time, the 1st and 3rd Wednesday of every month. This series aims to showcase new projects, technologies and ideas in biomedical ontology by featuring the work of a different collaborator each session. It is open to anyone interested, regardless of location or affiliation.