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"The value of any individual piece of knowledge is about the value of any individual piece of lego," Wilbanks said in a keynote address to the Open Access and Research Conference held in Brisbane last week. "It's not that much until you put it together with other legos." He says the ability to connect knowledge brings scientific revolutions. For example Watson and Crick's breakthrough on the structure of DNA involved them reading all the scientific papers on nucleotide bonding and encoding it in the form of a physical model, says Wilbanks. But this kind of "human scale" analysis is no longer feasible in an age when automated laboratory processes generate vast amounts of information faster than the human mind can process it. "For example, we have 45,000 papers about one protein or one gene," says Wilbanks. He says a scientist might once have analysed the impact of one drug on one gene, but now pipetting robots are capable of analysing 25,000 genes at a time. "Most of the research says the smartest of us can handle five or six independent variables at once - not 25,000," he says