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Nathan Goodyear

Dehydroepiandrosterone supplementati... [J Clin Endocrinol Metab. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23824417

DHEA fat mass men male hormone hormones elderly men

shared by Nathan Goodyear on 07 Apr 14 - No Cached
  • Nathan Goodyear on 07 Apr 14
     
    meta-analysis finds reduction in fat mass from DHEA in elderly men.  The authors propose that it is due to the conversion to other hormones.  
Nathan Goodyear

Low Vitamin D Status Has an Adverse Influence on Bone Mass, Bone Turnover, and Muscle Strength in Chinese Adolescent Girls - 0 views

jn.nutrition.org/...1002.long

vitamin d strength muscle

shared by Nathan Goodyear on 24 Aug 15 - No Cached
  • Nathan Goodyear on 24 Aug 15
     
    normal versus low vitamin D in adolescent girls is found to be associated with increased grip strenght and lower bone turnover with increased bone mass.
Nathan Goodyear

Reevaluation of the protein requirement in young men with the indicator amino acid oxidation technique - 0 views

ajcn.nutrition.org/...995.long

protein macronutrients nutrition diet men

shared by Nathan Goodyear on 21 Jul 15 - No Cached
  • the mean and population-safe protein requirements were estimated to be 0.93 and 1.2 g · kg−1 · d
  • diet containing 0.90 g · kg−1 · d−1 was at or above physiologic protein requirements for sedentary men
  • The current EAR recommendation and RDA for protein are 0.66 and 0.80 g · kg−1 · d−1, respectively. We believe that these recommendations are tentative because no long-term studies have suggested that these values would maintain nitrogen balance along with lean body mass, muscle mass, serum protein concentrations, immunity, functional capacity etc
  • ...2 more annotations...
  • a series of long-term balance studies (67-69) showed that intake of the proposed safe allowance of 0.57 g (70) egg protein resulted in negative nitrogen balance, loss of lean body mass, and deteriorating serum protein and transferase values unless additional energy or nonessential nitrogen was supplied
  • The results of the present study suggest that the current EAR recommendations (0.66 g · kg−1 · d−1) and RDA (0.80 g · kg−1 · d−1) for protein are underestimated at 29% and 33%, respectively
  • Nathan Goodyear on 21 Jul 15
     
    study looked at protein requirements in 8 "healthy" men.  This study pointed to 1.2 g/kg/day as an appropriate daily dietary protein intake for healthy men.  This far exceeds levels per RDA.
Nathan Goodyear

American Journal of Gastroenterology - Abstract of article: Effects of Branched-Chain Amino Acids Supplementation in Patients With Cirrhosis and a Previous Episode of Hepatic Encephalopathy: A Randomized Study - 0 views

www.nature.com/...ajg20119a.html

BCAA branched chain amino acids Muscle mass hepatic encephalopathy liver cirrhosis disease

shared by Nathan Goodyear on 05 Oct 15 - No Cached
  • Nathan Goodyear on 05 Oct 15
     
    BCAA supplementation does not inhibit recurrences of hepatic encephalopathy, but it does improve muscle mass.
Nathan Goodyear

Interorgan ammonia trafficking in liver disease. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19067143

liver disease cirrhosis ammonia muscle Muscle mass

shared by Nathan Goodyear on 05 Oct 15 - No Cached
  • Nathan Goodyear on 05 Oct 15
     
    The primary metabolizer of ammonia is the liver; however, in liver failure, muscle mass becomes a second means to metabolize excessive ammonia.
Nathan Goodyear

Fundamental Aspects of Hypogonadism in the Aging Male - 0 views

www.ncbi.nlm.nih.gov/...PMC1502324

low T low Testosterone muscle muscle mass hypogonadism men male hormone hormones Testosterone aging

shared by Nathan Goodyear on 10 Apr 15 - No Cached
  • Nathan Goodyear on 10 Apr 15
     
    good discussion of low T effect on a man's metabolism: particularly muscle mass.
Nathan Goodyear

Testosterone dose-response relationships in health... [Am J Physiol Endocrinol Metab. 2001] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...11701431

testosterone replacement response muscle mass strength

shared by Nathan Goodyear on 02 Mar 11 - No Cached
  • Nathan Goodyear on 02 Mar 11
     
    testosterone in those with low T increases muscle mass and strength
Nathan Goodyear

Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans - 0 views

www.ajcn.org/...1118.abstract

conjugated linoleic acid weight loss

shared by Nathan Goodyear on 23 Mar 11 - No Cached
  • Long-term supplementation with CLA-FFA or CLA-triacylglycerol reduces BFM in healthy overweight adults
  • Nathan Goodyear on 23 Mar 11
     
    CLA, conjugated linoleic acid, supplementation reduces body fat mass
Nathan Goodyear

Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans - 0 views

www.ajcn.org/...1203.abstract

CLA conjugated linoleic acid fat overweight obesity

shared by Nathan Goodyear on 24 Aug 11 - No Cached
  • Nathan Goodyear on 24 Aug 11
     
    CLA shown to reduce fat mass in meta-analysis
Nathan Goodyear

ScienceDirect - Toxicology Letters : Ex vivo study of incorporation into adipocytes and lipolysis-inhibition effect of polycyclic aromatic hydrocarbons - 0 views

www.sciencedirect.com/science

PBA obesity overweight polycyclic aromatic hydrocarbons

shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • we therefore suggest that B[a]P may play a central role in carcinogenesis not only by inducing cancer through its mutagenic properties, but also by increasing the bioaccumulation capacity of the adipose tissue mass.
  • Nathan Goodyear on 06 Apr 11
     
    PBA plays role in increased fat mass
Nathan Goodyear

α-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-γ coactivator-1α signaling in the skeletal muscle of aged mice - 0 views

www.metabolismjournal.com/...abstract

alpha lipoic acid ALA

shared by Nathan Goodyear on 07 May 11 - No Cached
  • LA improves skeletal muscle energy metabolism
  • LA increases lean mass loss
  • Nathan Goodyear on 07 May 11
     
    alpha lipoic acid improves energy production, lean mass and weight loss
Nathan Goodyear

SpringerLink - Amino Acids, Volume 39, Number 2 - 0 views

www.springerlink.com/...f5371224753j8763

L-Arginine mitochondria fat loss weight muscle mass overweight obesity

shared by Nathan Goodyear on 11 Jul 11 - No Cached
  • Nathan Goodyear on 11 Jul 11
     
    L-Arginine stimulates mitochondrial function, resulting in fat loss and increase muscle mass
Nathan Goodyear

Longitudinal relationships of circul... [J Clin Endocrinol Metab. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24628559

Testosterone low T free Estradiol Estrone muscle mass strength elderly men male hormone hormones men's health

shared by Nathan Goodyear on 24 Mar 14 - No Cached
  • Nathan Goodyear on 24 Mar 14
     
    Declining Testosterone, calculated free Testosterone, Estradiol, and Estrone levels appear to be associated with muscle mass/strength decline in elderly men.  This points to a global decrease in HPA function rather than an individual, specific hormone deficiency.
Nathan Goodyear

Cardiovascular risk associated with tes... [Expert Opin Drug Saf. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25139126

cardiovascular disease risk men male hormone hormones Testosterone low T low Testosterone fat muscle muscle mass metabolism

shared by Nathan Goodyear on 21 Aug 14 - No Cached
  • Nathan Goodyear on 21 Aug 14
     
    Testosterone therapy in men with low Testosterone, over 34 weeks, found to improve metabolism, reduce fat and increase muscle mass and not associated with any increase cardiovascular risk.
Nathan Goodyear

International Journal of Impotence Research - Obesity, low testosterone levels and erectile dysfunction - 0 views

www.nature.com/...ijir200842a.html

low T low Testosterone men male hormone hormones ED erectile dysfunction Testosterone diabetes metabolic syndrome obesity

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Studies have shown that ED may be an early biomarker of general endothelial dysfunction, atherosclerosis and CVD
  • testosterone treatment of hypogonadal young and older men improves sexual function, increases lean mass and decreases fat mass
  • In men with low serum testosterone (for example, <8 or 230 nmol l−1) with obesity, metabolic syndrome and diabetes mellitus, treatment with testosterone is warranted
  • ...12 more annotations...
  • In obese middle-aged men, testosterone treatment reduced visceral adipocity, insulin resistance, serum cholesterol and glucose levels
  • testosterone replacement has a favorable impact on body mass, insulin secretion and sensitivity, lipid profile and blood pressure in hypogonadal men with the metabolic syndrome as well as type 2 diabetes mellitus
  • Testosterone significantly inhibits lipoprotein lipase activity, which reduces triglycerides uptake into adipocytes in the abdominal adipose tissue
  • testosterone treatment decreased endogenous inflammatory cytokines (tumor necrosis factor-α and IL-1β) and lipids (total cholesterol) and increased IL-10 in hypogonadal men
  • Testosterone treatment reduced leptin and adiponectin levels in hypogonadal type 2 diabetic men after 3 months of testosterone replacement
  • available data clearly show a relationship between obesity, low testosterone levels and ED
  • Obesity adversely affects endothelial function and lowers serum testosterone levels through the development of insulin resistance and metabolic syndrome
  • Metabolic disturbances as well as production of cytokines and adipokines by inflamed fat cells may be causal factors in the development of ED
  • The onset of ED and the associated risk of CVD may be delayed through lifestyle modifications that affect obesity, such as diet and exercise
  • Very low testosterone levels contribute to the development of ED in obesity, metabolic syndrome and type 2 diabetes mellitus
  • Obesity is associated with low total testosterone levels that can be explained at least partially by lower sex hormone-binding globulin (SHBG) in obese men
  • epidemiological studies have shown a negative correlation between BMI and total testosterone and to a lesser extent with free and bioavailable (biologically active) testosterone levels
  • Nathan Goodyear on 27 Jan 15
     
    Obesity is associated with low Testosterone and ED in men.
Nathan Goodyear

Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis | Endocrinology and Metabolism - 0 views

ajpendo.physiology.org/...E820.short

Testosterone men male hormone hormones muscle muscle mass protein strength metabolism

shared by Nathan Goodyear on 06 Mar 15 - No Cached
  • Nathan Goodyear on 06 Mar 15
     
    small study finds that Testosterone therapy in elderly men increased protein synthesis, muscle mass, and increase in strength.
Nathan Goodyear

Sarcopenia and Age-Related Endocrine Function - 0 views

www.hindawi.com/...cta

Testosterone low T low testosterone low T muscle mass sarcopenia aging

shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    Good discussion of sarcopenia.  They article looked at the evidence of Testosterone and found the evidence pointed to improved lean muscle mass; but not a direct cause effect of low T and sarcopenia.
Nathan Goodyear

A Lower-Carbohydrate, Higher-Fat Diet Reduces Abdominal and Intermuscular Fat and Increases Insulin Sensitivity in Adults at Risk of Type 2 Diabetes - 0 views

jn.nutrition.org/...177S.abstract

nutrition diet high fat diet low carb diet fats carbohydrates weight fat fat mass insulin resistance obesity diabetes TNF-alpha insulin sensitivity

shared by Nathan Goodyear on 23 Mar 15 - No Cached
  • Nathan Goodyear on 23 Mar 15
     
    Diet higher in fats and lower in carbs associated with a reduction in weight, fat mass, improved insulin sensitivity, lowered fasting glucose, and a reduction in TNF-alpha
Nathan Goodyear

THERAPY OF ENDOCRINE DISEASE: Testosterone supplementation and body composition: results from a meta-analysis study. - 0 views

www.eje-online.org/...EJE-15-0262.abstract

low T low Testosterone Testosterone fat muscle mass metabolism body composition cholesterol triglycerides HDL men male hormones

shared by Nathan Goodyear on 19 Nov 15 - No Cached
  • Nathan Goodyear on 19 Nov 15
     
    new study finds Testosterone therapy in men with low T significantly reduces fat, increases lean muscle mass, and reduces fasting glucose and insulin levels.  Improvements in total cholesterol, triglycerides and HDL was also seen.  Only abstract available currently.
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