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Nathan Goodyear

The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies | C... - 0 views

  • In this group, the 5-year survivalrateduesolelytocytotoxicchemotherapywas14%
  • There is also no convincing evidence that usingregimens with newer and more expensive drugs are anymore beneficial than the regimens used in the 1970s
  • two systematic reviews of chemotherapy inrecurrent or metastatic breast cancer have not been able toshow any survival benefit
  • ...12 more annotations...
  • The five most common adult malignancies (colorectal, breast, prostate, melanoma and lung cancer)
  • n breast cancer, the optimal regimen(s) for cytotoxicchemotherapy in recurrent/metastatic disease are still notdefined, despite over 30 years of ‘research’ and a plethora of RCTs since the original Cooper regimen was published in1969
  • The five most ‘chemo-sensitive’ cancers,namely testis, Hodgkin’s disease and non-Hodgkin’s lym- phoma, cervix and ovary
  • only 13 out of the 22 malignancies evaluated showed any improvement in 5-year survival, and theimprovement was greater than 10% in only three of those13 malignancies
  • the contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults is 2.3% in Australia and 2.1% in the USA
  • a benefit of less than 2.5% is likely to be applicable in other developed countries
  •   Overview The Contribution o
  • the benefit of cytotoxic chemotherapy may have been overestimated for cancers of oesophagus, stomach,rectum and brain.
  • this reflects the presentation of results as a ‘reduction in risk’ rather than asan absolute survival benefit[89,90]and by exaggerating theresponse rates by including ‘stable disease’
  • recent studies have documented impaired cognitive function inwomen receiving adjuvant treatment for breast cancer
  • the 5-year survival rate due solely to cytotoxicchemotherapy was 1.6%
  • the value of palliative chemotherapy has beenquestioned
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    Incredibly low impact of cytotoxic chemotherapy despite its wide spread utilization.  This article referenced cost yet did not evaluate the cost of cytotoxic side effect.  The question to answer: is Cytotoxic chemotherapy a valid treatment, at all, for the majority of cancers.
Nathan Goodyear

Histamine dihydrochloride and low-dose interleukin-2 as post-consolidation im... - 0 views

  • IL-2 is a central T cell-derived cytokine, which induces NK cell and T cell proliferation, differentiation and activation, and also stim-ulates the production of secondary immunostimulatory cytokines
  • combination of histamine and IL-2 thus triggers efficient NK cell-mediated killing of several types of leukemic cells, including freshly recovered human AML blasts
  • histamine improves the effects of IL-2 on T cell activation
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  • principal action of histamine is to protect cytotoxic lymphocytes from myeloid-cell-induced inactivation, thus improving the efficiency of the T and NK cell stimulation achieved by IL-2
  • random-ized Phase II study of patients with renal cell carcinoma further support the suggestion that the combination of HDC and IL-2 improves lymphocyte functions
  • HDC improves the effectiveness of IL-2-induced T and NK cell activation in cancer patients, as predicted in preclinical models
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    histamine dihydrochloride enhances immune effects of NK cells in IL02 therapy; specifically in this analysis in AML, the histamin prevented inactivation of the IL-2 activated NK cells.
wheelchairindia9

Toilet Wheelchair - 0 views

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    Commode chairs are best suited for people who cannot use a regular toilet. The chairs enable patients who have limited mobility due to an accident or any medical condition to use the toilet with ease. The chair allows the patient to use the toilet without causing discomfort to the legs and back. The chair can be used by people who are restricted to a bed or wheelchair. A commode chair is a useful mobility for people of any age who are recovering from injury or surgery. The chair offers a reasonable level of independence to the user; a handy device to be presented to someone who needs it and for whom care. Commode Wheelchairs which are specially designed for aged and physically challenged people. These wheelchairs can be used for indoor toilet purposes. Fabricated using quality raw material, these wheelchairs are suitable for domestic and hospital purpose. There are two types for handicapped and disability product like Commode Wheelchair- Commode Wheelchair Rainbow 6 Commode Wheelchair Rainbow 7 Commode Wheelchair Rainbow 6: Karma commode wheelchair rainbow 6 comes with lot of exiting features for elderly or physically challenged person who want commode in wheelchair. Karma Rainbow 6 has single seat with center cut commode having cushion cover on top and removable pan or plastic commode seat with pot. Commode Wheelchair Rainbow 6 Features: Frame Material : M.S.Chrome Plated Single Seat with center cut commode Both Option Available In Single Seat Plastic Commode Seat With Pot. Cushioned Top Cover Square Pan Commode Pan Removable Pan Commode Wheelchair Rainbow 6 Measurements: Frame Style : Foldable Open Position Wheel To Wheel Width In : 26" (Inches) Seat Width : 18" (Inches) Total Width in Closing Position : 11" (Inches) Rear Wheel Size : 24" (Inches) Front Wheel Size : 8" (Inches) Seat to Floor Height : 19" (Inches) Seat Depth : 18" (Inches) Total Height : 34" (Inches) Max User Weight Capacity : 110 (kgs)
indian-health

Top Cardiologists in Bangalore Providing Life-Saving Heart Valve Repair Without Open-He... - 0 views

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    About a year ago, top cardiologists in Bangalore told Arthur Brown the only option to repair his leaky tricuspid heart valve was open-heart surgery. Unfortunately, that surgery comes with serious risks that Arthur, who also had an unrelated lung tumor removed in May 2019, wasn't comfortable taking. According to Top cardiologists in Bangalore, "
spineneuro

Success Rate of Brain Tumor Surgery in India 2021 Doubles Life Expectancy for Brain Cancer - 0 views

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    The Blue 400 is one of many advanced technologies available at the top 10 hospitals for brain tumor surgery in India. "Technology of this type is the future of neurosurgical care. We are thrilled to be one of the first in the region to provide our neurosurgeons with the technology," said the best of the top 10 brain tumor surgeons in India. International Helpline Number : +91-9325887033 Email id: enquiry@spineandneurosurgeryhospitalindia.com
indian-health

Cardiac Surgery India Boosts Survival in Heart Patients - 0 views

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    #Top10heartsurgerieshospitals of #India are equipped with excellent infrastructure, #Bestdoctors and #highstandards of #Operation. Read More https://bit.ly/3AOHLDd Call Us +91-9371136499 Mail Us contact@indianhealthguru.com #CardiacSurgeryIndia #CostofCardiacSurgery #AffordableCardiacSurgery #BestHeartSurgeryHospitals #Top10HeartSurgeons #Top10HospitalsforCardiacSurgeries
spineneuro

Children With Brain Tumors Will Benefit From Targeted Treatment - 0 views

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    List of top brain tumor surgeons India, accomplished a large-scale examination of 241 infants from around the world identified with glioma brain tumors - working with colleagues at the list of top 10 hospitals for brain tumor surgery India.
indian-health

Top Heart Surgeons In India Offering Remarkable Techniques - 0 views

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    Top heart surgeons in India are geared up with the modern day technology and top-notch facilities to permit the treatment of challenging and complex cardiac instances.
indian-health

Top 10 Valve Replacement Surgeons of India Offering Remarkable Techniques - 0 views

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    Each year, the top 10 valve replacement surgeons of India treat thousands of patients for valve replacement surgery India from within the country and abroad. Read More https://medical-tourism-magazine.blogspot.com/2021/12/unitedstates-top-10-valve-replacement-surgeons-of-india-offering-remarkable-techniques.html
indian-health

Your Search For Affordable Dental Surgery India Ends at Top 10 Dental Surgeons of India - 0 views

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    This is encouraging increasingly more people to choose #Affordabledentalsurgerycost in #India, wherein they are able to save 60 to 70 % of their savings. #Top10dentalsurgeonsofIndia offers long-lasting and natural-looking results like #Healthyteeth. Read More https://medical-tourism-magazine.blogspot.com/2021/12/britain-affordable-dental-surgery-india-ends-at-top-10-dental-surgeons-of-india.html
indian-health

How Top Cardiac Hospitals in Bangalore Raising the Bar for Cardiac Care In India - 0 views

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    Cardiac surgery India is especially appealing to worldwide tourists as it now not only lets in them to chop down charges but it also offers them the gain of undergoing process surgery by top 12 cardiologists in Bangalore.
wheelchairindia9

Shower Wheelchair - 0 views

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    Commode chairs are portable toilets, designed to be placed at the bedside of a disabled individual whose activity is very limited. It is typically consist of a frame and a waste receptacle that can be easily removed and emptied. Having such a device close at hand is especially helpful for those too debilitated to make the trip to the bathroom. So, if someone close to needs the support and convenience that commodes can offer, the right place. Adapted and assisted toileting systems help provide independence while being designed to be practical, versatile and comfortable, as well as, easy to clean. These adjustable toilets and commodes can be used as a freestanding commode chair, over the toilet, on the toilet, or as a shower chair. Commode Wheelchair Rainbow 6 Features: Frame Material : M.S.Chrome Plated. Single Seat with center cut commode. Both Option Available In Single Seat. Plastic Commode Seat With Pot. Cushioned Top Cover. Square Pan Commode Pan . Removable Pan. Commode Wheelchair Rainbow 6 Measurements: Frame Style : Foldable Open Position Wheel To Wheel Width In : 26" (Inches) Seat Width : 18" (Inches) Total Width in Closing Position : 11" (Inches) Rear Wheel Size : 24" (Inches) Front Wheel Size : 8" (Inches) Seat to Floor Height : 19" (Inches) Seat Depth : 18" (Inches) Total Height : 34" (Inches) Max User Weight Capacity : 110 (kgs) Net Weight : 19.5 (kgs) Armrest : Fixed Footrest : Fixed Wheel Quality : Rear Tyre Solid Tube Less Rear Wheel Lock : Yes Hand Brakes : No Drop Back Handle : No Providing a wide range of commode wheelchairs which are specially designed for aged and physically challenged people. These wheelchairs can be used for indoor toilet purposes. Fabricated using quality raw material, these wheelchairs are suitable for western as well as Indian toilets. This advanced technology involved wheelchair has a comfortable seat and made of a strong steel frame. This chair is very durable
krsnaphysio1

Physiotherapist in Gurgaon - 0 views

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    Since its establishment in the year 2011, Krshna Physio Plus is aimed to provide patients with comprehensive, high quality and professional physiotherapy treatments and rehabilitation to people in need. The efficient team of three, Dr. Ravi Sahauta - A very well-known complex trauma surgeon and Orthopaedician, Dr. Dharm Pal Sharma - an ex-Air force Physio trainer and Dr. Parmila Sharma - an experienced and talented physio expert, Krshna Physio Plus is counted among the well-known Physiotherapy clinic in Gurgaon and Delhi/NCR regions.  This clinic is one of the oldest organizations which was started with a vision to help people suffering from diverse dysfunctionalities with proper guidance and treatment which encompasses mainly physical, psychological, emotional, and social well being. With 8 centers in Delhi/NCR and Bihar, we are aimed at setting over 300 centers across Asia by 2020 and become the Physiotherapy clinic in Gurgaon.  Moreover, KRSNA Physio Plus is well equipped with various advanced facilities and equipment used to treat people to assure patient satisfaction and fast recovery. We have with us Top Physiotherapist in Gurgaon and Delhi/NCR regions with us who are specialized in offering treatment in physiotherapy dealing with Orthopedic, Neurological, Pediatric, Cardio-pulmonary, and Sports Injury, etc. All the experts here put their best for providing the best results.  Our experienced team of doctors and physiotherapists in Gurgaon who would be better able to diagnose what might be making it impossible for you to crane your neck, or pick articles off the floor, or simply kneel before your deity. Sports-Related Injuries Could Happen to Anyone It could be just that badminton match on a winter evening, or an office football match. Before you realize what is happening you've pulled a back muscle or your hamstring. Playing tug-of-war in colleges and office parties is fraught with the risk of a rotator cuff injury. Cricketers diving to save
spineneuro

Top VBT Surgeons of India in 2021 Using FDA-Approved Spinal Tethering Device - 0 views

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    "As patients emerge as increasingly interested in non-fusion surgical alternatives for treating scoliosis whilst a back brace has not been effective, vertebral body tethering is an opportunity that preserves movement and flexibility-especially in younger patients as they continue to grow," says top VBT surgeons of India in 2021. For Enquiry Helpline Number: +91-9325887033 Email id: enquiry@spineandneurosurgeryhospitalindia.com
spineneuro

Affordable Top Hospitals for Spinal Fusion India Leads to Better Outcomes - 0 views

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    Affordable top hospitals for spinal fusion India are recommended while non-invasive methods have failed to provide relief from pain. The cost of spine surgery offered by affordable spinal fusion doctors in India is almost 40-70% lower in comparison to the US and UK. Helpline Number: +91-9325887033 Email id: enquiry@spineandneurosurgeryhospitalindia.com
indiacardiacsurg

Cheapest top 10 heart valve surgeons in India Launches new Cardiac Program - 101 Press ... - 0 views

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    The heart valve program at affordable low price hospitals for heart valve repair India brings collectively cheapest top 10 heart valve surgeons in India to assess, treat and provide long-term take care of patients with heart valve conditions. International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
indiacardiacsurg

New Technique by Low Cost Top 10 Heart Valve Surgeons in India Safer for Some High-Risk... - 0 views

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    "All patients had a successful TAVR without a coronary obstruction, stroke, or any major worry," stated low-cost top 10 heart valve surgeons in India. "They have been doing very well as they reached the 30-day-mark after undergoing the procedure." For Consultation International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
spineneuro

Expert Hands, Healing Spines: Manipal Hospital's Top Spine Specialist in Action - 0 views

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    Top spine specialist Manipal Hospital prioritizes exceeding his patients' expectations, offering focused and high-quality care. Utilizing state-of-the-art equipment, he treats everyone with compassion, specializing in safe spine surgery.
indian-health

Cardiac Surgeons in Mumbai Opens the Door to Your New Life - 0 views

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    Cardiac surgery in India is available at a fraction of the cost international patients would have to pay elsewhere. The low cardiac surgery cost in India attracts hundreds of cardiac patients from abroad. In comparison to the western nations such as Britain and the US, the cardiac surgery cost in India is just a fraction of what it costs there.Top heart hospitals of Mumbai offer healthcare services at extremely affordable rates, backed with high-quality results as far as global patients all across the world are concerned. The top heart hospitals of Mumbai keep good quality and are equipped with a skilled team of surgeons using robotic surgery in India.
spineneuro

Get New-Age Technology and Expertise At Top Hospitals for Brain Tumor India - Spine and... - 0 views

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    It is been observed that brain tumor surgery in India is around 60% lesser than in other western advanced countries. That is why overseas patients choose India for their brain tumor surgery because of professional surgeons, top brain tumor hospitals in India, and affordable cost.
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