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"Similarly, how should cancer biologists think about cancer cells capable of producing vascular endothelial growth factor, a protein that promotes the growth of blood vessels? Clearly, the importance of this protein only makes sense when thinking about a cancer cell's environment: how close it is to blood vessels that it can exploit, for example."

"Die Forscher um Juniorprofessor Dr. Martin Thanbichler von der Philipps-Universität beschreiben die neu entdeckte Struktur in der aktuellen Ausgabe der Fachzeitschrift „Cell", die am 7. Dezember erscheint. „Für Bakterien ist dies das erste Beispiel einer Barriere, welche die Proteindiffussion einschränkt", erklärt Thanbichler, der eine Arbeitsgruppe am Marburger Max-Planck-Institut für terrestrische Mikrobiologie leitet und als Seniorautor des Aufsatzes firmiert. Er und sein Team untersuchten das Modellbakterium Caulobacter crescentus, das an einem Ende einen Stiel bildet, der durch Querbänder unterteilt ist. Er dient vermutlich als Abstandshalter, der die Zelle bei Nährstoffmangel von der Oberfläche entfernt und so in Bereiche erhöhter Nährstoffkonzentrationen bringt."

"Tissue engineering is often thought of as a "Frankenstein-type" science where scientists build living tissues from otherwise "dead" tissues and organs. However, current advances in technology mean bringing life to cadaveric tissues is becoming more and more sophisticated: less of the lightning strikes and more stem cells and 3D printing!"

The Singularity is a VERY rapid intelligence explosion. Each year we progress quicker. Visualize perfect immortality, eternal youth for everyone, no wrinkles. Every illness will be cured. Everything will be free, no poverty. We will colonize and explore Space. Our bodies and minds will be improved via genetic and technological modification. It's all about Artificial Intelligence, synthetic biology, biotech, nanotech, nanobots, robotics, 3D-Printing, DNA manipulation, Stem Cells. The Singularity is massively awesome utopia, perfect happiness.

"uBiome is a citizen science project that allows the public access to cutting edge sequencing technology to understand their health through the microbiome. How does the microbiome affect my health? We are all covered in trillions of microbes -- in fact, they outnumber human cells 10:1. The trillions of bacteria live on and in us are collectively called the microbiome. Like the rainforest, the healthy human microbiome is a balanced ecosystem. The correct balance of microbes keeps potential pathogens in check and regulates our immune system. Microbes also perform essential functions such as digesting food and synthesizing vitamins. Studies have also linked the microbiome to human mood and behavior, as well as many gut disorders, eczema, and chronic sinusitis."

The Encyclopedia of DNA Elements (ENCODE) Consortium is an international collaboration of research groups funded by the National Human Genome Research Institute (NHGRI). The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active.

"Over the last 10 years, MIT biologist Leonard Guarente and other researchers have demonstrated that very-low-calorie diets provoke a comprehensive physiological response, which promotes survival due to a set of proteins called sirtuins. A new report by Guarente published online in Cell has now demonstrated that sirtuins may also have a key part in the psychological response to dietary restriction. "

"I am going to try and experiment within an experiment today. I cloned a couple genes from yeast and have been spending months now trying to get them into several vectors for my combinatorial overexpression project. However, as it goes with wet messy biology, this seemingly simple process has been fighting me tooth and nail. I have retrieved one good clone out of 56 minipreps (plasmid construct isolation) and tried several ligations. So I have tripled down this week. In the picture here, I have 32 tubes, each with 5 individual E. coli colonies. That is a grand total of 160 isolates. 1.5 mL of cells have been transferred from overnight cultures and I am about to spin, lyse, and retrieve."

great science videos, the cell

http://www.ted.com In his lab, Martin Hanczyc makes "protocells," experimental blobs of chemicals that behave like living cells. His work demonstrates how life might have first occurred on Earth ... and perhaps elsewhere too.

"The SOS-Ras-Raf-MAPK cascade plays a central role here. In about 25% of human tumors, Ras proteins are present in structurally altered forms that enable them to release a flux of mitogenic signals into cells, without ongoing stimulation by their normal upstream regulators (Medema and Bos 1993). We suspect that growth signaling pathways suffer deregulation in all"

dass bei Mäusen mindestens 2 der 3 zur Krebstherapie zugelassenen Angiogenese-Hemmer die Bösartigkeit von Tumoren erhöhen können (Cancer Cell 2009, Band 15: Seite 220 und 232). Wurden krebskranke Labortiere mit den Wirkstoffen Sunitinib oder Sorafenib behandelt, verlangsamte sich einerseits das Tumorwachstum deutlich, andererseits drangen die Tumore verstärkt in das umliegende Gewebe ein und bildeten mehr Metastasen. .. Offenbar verlangsamen Angiogenese-Hemmer zunächst das Wachstum eines Tumors, bis dieser auf das knappe Nährstoffangebot reagiert und sich gegen das Aushungern zur Wehr setzt. „Möglicherweise liegt das daran, dass ein Tumor sein Wachstumsverhalten ändert, wenn er nicht mehr ausreichend versorgt wird. Indem er in benachbartes Gewebe eindringt und Tochtergeschwülste bildet, könnte er versuchen, wieder mehr Nachschub zu bekommen

Clay Adams Serofuge 2002 is a versatile system that has proven to be very useful for conducting blood grouping, cross matching, typing, and other cell washing procedures.

"Researchers say they want to emphasize, however, that the HPV vaccine commonly used by millions of women around the world is perfectly safe if done prior to infection with the virus. The concerns raised by this study relate only to viral therapies or possible use of a therapeutic vaccine after the virus has already been integrated into human cells. "It's been known for decades that only women with prior infection with HPV get cervical cancer," said Andrey Morgun, an assistant professor and a leader of the study in the OSU College of Pharmacy. "In about 90 percent of cases it's naturally eliminated, often without any symptoms. But in a small fraction of cases it can eventually lead to cancer, in ways that have not been fully understood.""

"100,000 skin samples every year (that's 5 square meters of skin or a full cow's-worth annually) at its lab in Lyon. Currently, the company receives bits of donor skin from plastic surgery procedures. Then L'Oreal breaks the samples down into individual cells, re-cultures and grows them into .5 cm testing squares. The whole process takes about a week to complete but could soon be done much faster thanks to Organovo's NovoGen Bioprinting Platform. ... The bioprinter has already partnered with Merk to create liver and kidney tissues"

Jaincolab made 9V battery holder with wire leads, with switch and cover. battery holder with wire leads, with switch and cover.

Jaincolab is one of the leading manufacturers and importers of best quality AA Battery Holder with wires and clips.