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Numbers Games Devised to Aid People with "Dyscalculia": Scientific American - 0 views

  • team now has tentative plans to evaluate its software with researchers at the Cuban Neurosciences Center and the University of Pedagogical Sciences in Havana next year
  • also placing the game in other countries, including China and Singapore.
  • Cubans, curiously, are putting money into this, even though they've got very little
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  • hopes that Number Sense — if it can improve dyscalculia — will help him in the academic debate over the cognitive basis of numeracy.
  • the interest of the children was to have a fun game full of ideas and variety, and that was not very compatible with an analytic approach
Mars Base

Ultrathin flexible brain implant offers unique look at seizures - 0 views

  • Researchers funded by the National Institutes of Health have developed a flexible brain implant that could one day be used to treat epileptic seizures
  • a type of electrode array that conforms to the brain's surface – to take an unprecedented look at the brain activity underlying seizures
  • Someday, these flexible arrays could be used to pinpoint where seizures start in the brain and perhaps to shut them down
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  • These flexible electrode arrays could significantly expand surgical options for patients with drug-resistant epilepsy
  • In an animal model, the researchers saw spiral waves of brain activity not previously observed during a seizure
  • Similar waves are known to ripple through cardiac muscle during a type of life-threatening heart rhythm called ventricular fibrillation.
  • A stimulating electrode array might one day be designed to suppress seizure activity, working like a pacemaker for the brain
  • The brain contains billions of interconnected neurons that normally transmit electrical pulses
  • During a seizure, these pulses occur in abnormal, synchronized, rapid-fire bursts that can cause convulsions, loss of consciousness and other symptoms
  • is made of a pliable material that is only about one quarter the thickness of a human hair
  • It contains 720 silicon nanomembrane transistors in a multiplexed 360-channel array, which allow for minimal wiring and dense packing of the electrodes
  • The flexibility of the array allows it to conform to the brain's complex shape, even reaching into grooves that are inaccessible to conventional arrays
  • the array could be rolled into a tube and delivered into the brain through a small hole rather than by opening the skull
  • The researchers tested the flexible array on cats. Although mice and rats are used for most neuroscience research, cats have larger brains that are anatomically more like the human brain, with simplified folds and grooves
Mars Base

Memories 'geotagged' with spatial information - 0 views

  • Using a video game in which people navigate through a virtual town delivering objects to specific locations, a team of neuroscientists
  • has discovered how brain cells that encode spatial information form "geotags" for specific memories and are activated immediately before those memories are recalled.
  • work shows how spatial information is incorporated into memories and why remembering an experience can quickly bring to mind other events that happened in the same place
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  • findings provide the first direct neural evidence for the idea that the human memory system tags memories with information about where and when they were formed
  • this study involved playing a simple video game on a bedside computer
  • The game in this experiment involved making deliveries to stores in a virtual city
  • The participants were first given a period where they were allowed to freely explore the city and learn the stores' locations
  • When the game began, participants were only instructed where their next stop was, without being told what they were delivering
  • After they reached their destination, the game would reveal the item that had been delivered, and then give the participant their next stop
  • After 13 deliveries, the screen went blank and participants were asked to remember and name as many of the items they had delivered in the order they came to mind
  • This allowed the researchers to correlate the neural activation associated with the formation of spatial memories (the locations of the stores) and the recall of episodic memories: (the list of items that had been delivered).
  • "Having these patients play our games allows us to record every action they take in the game and to measure the responses of neurons both during spatial navigation and then later during verbal recall."
  • By asking participants to recall the items they delivered instead of the stores they visited, the researchers could test whether their spatial memory systems were being activated
  • map-like nature of the neurons associated with spatial memory made this comparison possible
  • During navigation, neurons in the hippocampus and neighboring regions can often represent the patient's virtual location within the town
  • Using the brain recordings generated while the participants navigated the city, the researchers were able to develop a neural map that corresponded to the city's layout
  • As participants passed by a particular store, the researchers correlated their spatial memory of that location with the pattern of place cell activation recorded
  • With maps of place cell activations in hand, the researchers were able to cross- reference each participant's spatial memories as they accessed their episodic memories of the delivered items
  • given just the place cell activations of a participant
  • could predict, with better than chance accuracy, the item he or she was recalling
  • cannot distinguish whether these spatial memories are actually helping the participants access their episodic memories
  • seeing that this place cell activation plays a role in the memory retrieval processes
  • Earlier neuroscience research
  • had suggested the hippocampus has two distinct roles
  • tracking location information for spatial memory, and
  • recording events for episodic memory
  • This experiment provides further evidence that these roles are intertwined
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