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ScienceDaily (May 22, 2010) - A major step toward being able to regulate nerve cells externally with the help of electronics has been taken by researchers at Linköping University and the Karolinska Institute in Sweden. The breakthrough is based on an ion transistor of plastic that can transport ions and charged biomolecules and thereby address and regulate cells.

Apparently, if Facebook wanted to repair its reputation, all it had to do was seem like it was helping to topple an authoritarian regime. Now that the U.S. media is loudly pushing the idea that social media can change Egypt-and next, the world!-it makes Mark Zuckerberg's tendency to monetize every aspect of our online lives seem less important.

Vera Gorbunova and Andrei Seluanov of the University of Rochester have found that human cells undergoing oxidative stress caused by environmental chemicals or routine cellular processes produce a protein (SIRT6) that stimulates cells to repair DNA double-strand breaks, thought to be associated with premature aging and cancer. The team first measured levels of SIRT6 in stressed cells, then treated a second group of stressed cells with a drug that deactivates the protein. DNA repair in the second group stopped, confirming SIRT6′s role.  The team also found that SIRT6 acts in concert with another protein, called PARP1, to make the repairs. Furthermore, the team found that increased levels of SIRT6 lead to faster DNA repair. They suspect that the protein acts as a "master regulator," coordinating stress and DNA repair activities. Ref.: Zhiyong Mao, Christopher Hine, Xiao Tian, Michael Van Meter, Matthew Au, Amita Vaidya, Andrei Seluanov, and Vera Gorbunova. SIRT6 Promotes DNA Repair Under Stress by Activating PARP1. Science 17 June 2011: 1443-1446. [DOI:10.1126/science.1202723]

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