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"David Brin is a scientist and best-selling author whose future-oriented novels include Earth and Hugo Award winners Startide Rising and The Uplift War. (The Postman inspired a major film in 1998.) Brin is also known as a leading commentator on modern technological trends. His non fiction book -- The Transparent Society - won the Freedom of Speech Award of the American Library Association. For more informations see: http://www.davidbrin.com"

And yet, even today, seventeen years after the launch of the arxiv, every attempt to set up a preprint service for biologists has been a dismal failure, as noted by both Ginsparg and Timo Hannay (whose Science21 talk notes are up at Nature Networks. You can also get video and microblogging). Contrary to what a naive outsider's opinion might suggest, biologists appear to be highly resistant to the whole idea of sharing pre-publication results.

And now comes an era when we live immersed in computer-generated "virtual" realities, rendered through lavish games where ersatz selves get to do countless things that our mundane, fleshy selves cannot. Is it any wonder that some people have been talking about a near future when this process may reach its ultimate conclusion? When the denizens of Reality will not be able to verify, by any clear-cut means, that they aren't living in-or even existing because of-a simulation?

Arguments against technology: contrary to nature, to humans, to technology itself (self-destruction), to God.