An herbal extract inhibits the development of pancreatic cancer
(Philadelphia)An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its antiinflammatory properties, according to researchers from the kimmel cancer center at jefferson.The data were presented at the aacr 100th annual meeting 2009 in denver. beats by dre sale online
Nigella sativa seeds and oil are used in traditional medicine by many middle eastern and asian countries.It helps treat a broad array of diseases, including some immune and inflammatory disorders, dr.Arafat said.Thymoquinone almost completely abolished the expression of several inflammatory cytokines, including tnfalpha, interleukin1beta, interleukin8, cox2 and mcp1, an effect that was more superior to the effect of trichostatin a.
The herb also inhibited the activation and synthesis of nfkappab, a transcription factor that has been implicated in inflammationassociated cancer.Activation of nfkappab has been observed in pancreatic cancer and may be a factor in pancreatic cancer's resistance to chemotherapeutic agents.When animal models of pancreatic cancer were treated with thymoquinone, 67 percent of the tumors were significantly shrunken, and the levels of proinflammatory cytokines in the tumors were significantly reduced.
Inflammation has been implicated in the beats by dre outlet development of several solid tumor malignancies.Chronic pancreatitis, both hereditary and sporadic, is associated with the risk of developing pancreatic cancer.
"These are very exciting and novel results,"Dr.Arafat said. "Not only patients with chronic pancreatitis could benefit from this, but also several other groups with risk of development or recurrence of pancreatic cancer, such as highrisk family members and postsurgical patients.These potent effects show promise for the herb as a potential preventive and therapeutic strategy for pancreatic cancer.More importantly, the herb and oil are safe when used btsbydreuale moderately, and have been used for thousands of years without reported toxic effects. "Pancreatic cancer is the fourth leading cause of cancer death in the united states, with approximately 32, 000 deaths a year.Only five percent of individuals with pancreatic cancer live for at least one year after diagnosis.
(Philadelphia)An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its antiinflammatory properties, according to researchers from the kimmel cancer center at jefferson.The data were presented at the aacr 100th annual meeting 2009 in denver. beats by dre sale online
Nigella sativa seeds and oil are used in traditional medicine by many middle eastern and asian countries.It helps treat a broad array of diseases, including some immune and inflammatory disorders, dr.Arafat said.Thymoquinone almost completely abolished the expression of several inflammatory cytokines, including tnfalpha, interleukin1beta, interleukin8, cox2 and mcp1, an effect that was more superior to the effect of trichostatin a.
The herb also inhibited the activation and synthesis of nfkappab, a transcription factor that has been implicated in inflammationassociated cancer.Activation of nfkappab has been observed in pancreatic cancer and may be a factor in pancreatic cancer's resistance to chemotherapeutic agents.When animal models of pancreatic cancer were treated with thymoquinone, 67 percent of the tumors were significantly shrunken, and the levels of proinflammatory cytokines in the tumors were significantly reduced.
Inflammation has been implicated in the beats by dre outlet development of several solid tumor malignancies.Chronic pancreatitis, both hereditary and sporadic, is associated with the risk of developing pancreatic cancer.
"These are very exciting and novel results,"Dr.Arafat said. "Not only patients with chronic pancreatitis could benefit from this, but also several other groups with risk of development or recurrence of pancreatic cancer, such as highrisk family members and postsurgical patients.These potent effects show promise for the herb as a potential preventive and therapeutic strategy for pancreatic cancer.More importantly, the herb and oil are safe when used btsbydreuale moderately, and have been used for thousands of years without reported toxic effects. "Pancreatic cancer is the fourth leading cause of cancer death in the united states, with approximately 32, 000 deaths a year.Only five percent of individuals with pancreatic cancer live for at least one year after diagnosis.
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