PHE - Resources

"Today's infographic dives into some of the technological advances that are pushing the boundaries of modern healthcare, and what this could mean for the sector."

"To keep pace with the evolving ecosystem for precision medicine, pharma players must be attuned to three crucial components: data collection, individualized solutions, and supporting business models."

Welcome to the Empowered Patient Podcast with Karen Jagoda. This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients. Topics on the show include the emergence of personalized medicine and breakthroughs in genomics advances for aging in place using big data from wearables and sensors transparency in the medical marketplace challenges for connected health entrepreneurs The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors.

" CONNECT WITH US: ABOUT PMRI RESEARCH CONTACT US DONATE Alzheimer's Study Can Lifestyle Changes Reverse Alzheimer's Disease?"

"Learn more Click here to subscribe to the CTRI News and Funding Opportunities monthly newsletter. Learn more   Director's Message I am pleased to announce the availability of the ACTRI Virtual Research Desktop (VRD) for UC San Diego Health research scientists and staff. The service is a collaboration between ACTRI and UC San Diego Health System Information Services (IS). The VRD is a HIPAA-compliant virtual desktop that operates in a secure private cloud server environment managed by the ACTRI and housed in a UC San Diego data center. Read more from Director Gary S. Firestein, MD"

Click through to hear an 8 minute interview with Austin Durant, citizen experimenter and founder and chief fermentation officer, Fermenters Club and Vineet Pandey, lead designer and developer, Galileo. "Ever wonder if kombucha, the fermented tea drink, is actually good for you? Like many food and drinks touted as healthy, there hasn't been much scientific research to rely on and you'd just have to come to your own conclusions. Now a tool out of UC San Diego is empowering regular citizens to design experiments to test hypotheses and recruit participants, becoming scientists themselves. The tool is called Galileo and encourages participants to test their intuitions by asking questions like, can a vegan diet improve energy levels? Or does drinking coffee every day reduce the quality of sleep?"

A novel device and method for the objective measurement of pain and analgesic drug effect in children's

"Dear Practitioners,   It is with great pleasure that Daniela Carraro and myself will be co-teaching a transformational retreat with Jianshe Liu on March 5 - 8th, 2019 at Prince of Peace Abbey in Oceanside.   Jianshe has studied Zhineng Qigong since 1991 - his teaching is a direct transmission of authentic,  joyful presence and living each moment gracefully.   Jianshe, Dani and I are honored and humbled to come together and connect with you in this way. Please read below for more details, we look forward to sharing this experience with you.   Abundant blessings, Dani & Reyna"

"In 2009, Ms. Leon went to the WomenHeart Science and Leadership Symposium at the Mayo Clinic, where she met Dr. Sharonne N. Hayes, a professor of cardiovascular medicine at Mayo. At that time, the largest study on SCAD included 43 patients. "I walked up to Dr. Hayes and told her we had 70 people, and we wanted research," Ms. Leon recalled. "She was like, 'Wow.'" "Everything I learned about SCAD in my medical training was wrong," Dr. Hayes said. By 2010, with the help of Dr. Hayes, and subsequently SCAD Research Inc., an organization founded by Bob Alico, who lost his wife to SCAD, Dr. Hayes devised an innovative way to do research, using online networks of far-flung patients and analyzing genetic and clinical data. "We never imagined there would be 1,000 female patients in our virtual registry," Dr. Hayes said."

Sharon, telling your story this article is an act of bravery and determination. Your strength is an inspiration.

Mimi Guarneri on PBS!

"N-of-1 or single subject clinical trials consider an individual patient as the sole unit of observation in a study investigating the efficacy or side-effect profiles of different interventions. The ultimate goal of an n-of-1 trial is to determine the optimal or best intervention for an individual patient using objective data-driven criteria. Such trials can leverage study design and statistical techniques associated with standard population-based clinical trials, including randomization, washout and crossover periods, as well as placebo controls. Despite their obvious appeal and wide use in educational settings, n-of-1 trials have been used sparingly in medical and general clinical settings. We briefly review the history, motivation and design of n-of-1 trials and emphasize the great utility of modern wireless medical monitoring devices in their execution. We ultimately argue that n-of-1 trials demand serious attention among the health research and clinical care communities given the contemporary focus on individualized medicine. Keywords: clinical equipoise, early-phase trials, individualized medicine, n-of-1, remote phenotyping, single patient trial, treatment repositioning, wireless health"

I met Tahir Bhatti during my Ornish Lifestyle Medicine transformation at Jacobs Medical Center UCSD. Tahir would sub into our support group whenever Ozzie Gontang was traveling. He is a great teacher. "Holistic Healers, Wellness Coaches, and Life-partners, Tahir Bhatti & Ayesha Suneja  have spent the last 20 years researching, teaching and guiding others towards mind-body-spirit healing, transpersonal wellness and spiritual growth.   Originally from India and Pakistan, both Ayesha and Tahir were raised in cultures that naturally cultivated spirituality, meditation and holistic healing practices.   Their passion for integrating spirituality into their clinical work led them to further their studies in Eastern philosophy, meditation, soul consciousness and self-realization.   Due to their exposure to ancient Eastern philosophies at a young age and their extensive training in Western Medicine & Psychology, their eclectic studies are balanced in the Sciences and the Ancient Truths.     By integrating both philosophies Tahir and Ayesha have created a blend of Eastern and Western Coaching Practices that is truly unique."

"Meet Sharon Terry, a former college chaplain and stay-at-home mom who took the medical research world by storm when her two young children were diagnosed with a rare disease known as pseudoxanthoma elasticum (PXE). In this knockout talk, Terry explains how she and her husband became citizen scientists, working midnight shifts at the lab to find the gene behind PXE and establishing mandates that require researchers to share biological samples and work together."

"Xconomy San Diego -  LunaDNA, a startup that is offering individuals company stock in exchange for personal genomic and health information in a bid to build a database that could help advance scientific research, is merging its research platform with the Genetic Alliance's Platform for Engaging Everyone Responsibly (PEER)."

"The Society to Improve Diagnosis in Medicine (SIDM) is a non-profit organization that focuses on the issue of diagnostic error. Misdiagnosis is quite common in Lyme disease and the consequences can be devastating. The SIDM website recently featured the personal story of LymeDisease.org's Lorraine Johnson, and the lessons learned from her own experience with diagnostic error. It is re-published here with SIDM's permission."

Abstract: INTRODUCTION: Spasticity in chronic spinal cord injury is a condition that can have negative repercussions on the patient's quality of life. Its treatment is complex and sometimes the outcome is insufficient. Cannabinoids have recently been used in multiple sclerosis to successfully treat spasticity that is refractory to other therapies. AIM: To quantify the clinical response of a group of patients with spastic chronic spinal cord injury to the orally administered drug delta-9-tetrahydrocannabinol-cannabidiol (Sativex®) as medication for use in special situations. PATIENTS AND METHODS: The research consists of a six-month observational study in patients with chronic spinal cord injuries with refractory spasticity. The variables collected were: modified Ashworth scale, Penn spasm frequency scale, Numeric Rating Scale, and Visual Analogue Scale for pain. Additionally, clinical variables and side effects of the treatment were also collected. RESULTS: Fifteen patients took part in this study. A significant improvement was observed on three of the scales recorded: modified Ashworth scale (z = -2.97; p = 0.003), Penn spasm frequency scale (z = -2.76; p = 0.006) and Numeric Rating Scale (z = -3.21; p = 0.001). The use of the drug was withdrawn in two patients due to side effects. CONCLUSIONS: Sativex can be considered an alternative in patients with spasticity associated with chronic spinal cord injury for whom other therapeutic measures have been insufficient. Further studies need to be conducted before the use of this drug can be recommended and so as to define a complete profile of its long-term side effects.