PHE - Resources

Extensive slide-deck from Dr. Sharon Hausman-Cohen

"  Presented by the Law and Policy Working Group and Ethics Working Group Date: Friday, November 22, 2019, from 1:00 PM to 2:15 PM EST Presented by the Law and Policy Working Group and Ethics Working Group Date: Friday, November 22, 2019, from 1:00 PM to 2:15 PM EST"

"Our Co-Founder and Medical Director, Dr. Sharon Hausman-Cohen, received both her master's degree and medical degree from Harvard Medical School. She is board-certified in Family Medicine, a Fellow of the American Board of Integrative and Holistic Medicine, and board-certified in Integrative Medicine through the American Board of Physician Specialties.*  She has been practicing Full Spectrum Family Medicine and Integrative Medicine for more than 20 years."

American Nutrition Association The Genomics of Obesity Sharon Hausman-Cohen, MD The modernization of our society has contributed to higher rates of obesity through an environment that promotes increased caloric intake and decreased physical activity. However, recent studies suggest that genetics may contribute to 40-70% of obesity with the discovery of more than 50 genes that are strongly associated with obesity. Changes in the environment have significantly increased obesity rates over the last 20 years, and the presence or absence of genetic factors can protect us from or predispose us to obesity in conjunction with diet and lifestyle factors that support healthy weight. In this webinar, Dr. Hausman-Cohen will * Describe how the leptin pathway is interrelated to the functions of genes in the hypothalamus, as well as how inflammation, fat absorption and insulin can contribute to obesity. * Discuss how specific food intake can be linked to obesity risk and how weight loss can be individualized based on a patient's genomics. * Attain practical ways of discussing various obesity interventions and patterns with patients - whether or not practitioners have access to patient genomic data. Category"

Background With the rise of precision medicine efforts worldwide, our study objective was to describe and map the emerging precision medicine landscape. A Google search was conducted between June 19, 2017 to July 20, 2017 to examine how "precision medicine" and its analogous terminology were used to describe precision medicine efforts. Resulting web-pages were reviewed for geographic location, data type(s), program aim(s), sample size, duration, and the key search terms used and recorded in a database. Descriptive statistics were applied to quantify terminology used to describe specific precision medicine efforts. Qualitative data were analyzed for content and patterns.

"In this Sketchy EBM video, we explore the definition of Evidence-Based Medicine and a few of the risks."

"Neuroscientist Michael Merzenich looks at one of the secrets of the brain's incredible power: its ability to actively re-wire itself. He's researching ways to harness the brain's plasticity to enhance our skills and recover lost function. This talk was presented at an official TED conference, and was featured by our editors on the home page."

In 2008 Jeff Kaditz was rushed to the hospital after being hit by a car. He spent months in a hospital bed and had to learn to walk again. He was misdiagnosed twice before finding out he needed major surgery. Throughout the process he was frustrated by the lack of quantitative information that was available about his body, which led to a wide range of inconsistent diagnoses. Jeff imagined a day when everything about a person's body could be quickly measured, shared and analyzed. He started researching a solution and in 2015 he met Dr. Michael Snyder and Dr. Garry Choy. They immediately bonded over a shared vision that became Q.

"Meet Milli A self-teaching personalized medical intelligence platform built from real-time analysis of millions of patient/doctor interactions. The Medical Intelligence Platform™ makes it easy to capture, aggregate, and analyze comprehensive patient data with human-augmented Artificial Intelligence. We provide doctors with suggestions for the likely underlying dysfunctions that lead to disease, recommendations for follow up tests, and predictions for which intervention will be most effective for each patient. Our Virtual Health Assistant then provides intervention support to the patient and tracks their adherence and medical outcomes. This closed-loop process enables the platform to systematically learn from every provider/patient medical encounter to learn how to better prevent and reverse disease."

DeAunne Denmark, MD, PhD - OUR CORE PREMISE: To improve health, we must close the gap between what we know and what we do. "INGH has a new facility and venture that is the best I've seen anywhere to get a whole slew of high-resolution data collected in one shot. And supposedly, it is "not that expensive"...

Part clinic, part research lab, Lab100 uses precision diagnostics to empower patients and help scientists advance our understanding of human health.

Tempus is making precision medicine a reality. Through the power of artificial intelligence, we believe all patients will eventually be on their own personalized diagnostic and therapeutic path. With the world's largest library of clinical and molecular data, and an operating system to make that data accessible and useful, we enable physicians to make real-time, data-driven decisions to deliver personalized patient care and in parallel facilitate discovery, development and delivery of optimized therapeutic options for patients through distinctive solution sets.

HALE SPORTS LIVES AT THE INTERSECTION OF HIGH PERFORMANCE TRAINING AND LIFE SCIENCE RESEARCH. WE FOCUS ON PROFESSIONAL, COLLEGIATE, AND EXCEPTIONAL YOUTH ATHLETES TO EXPLAIN THE WAY THEY ARE BUILT AND HOW THEY FUNCTION. HALE HAS DEVELOPED A UNIQUE SYSTEM, BASED ON THE HALE ENGINE - A DATA-DRIVEN PLATFORM THAT INTEGRATES MULTIPLE TYPES OF DATA USING RIGOROUS AI TECHNIQUES - TO DELIVER PERSONALIZED, PRIORITIZED TRAINING AND HEALTH MANAGEMENT PLANS TO ATHLETES.

Lab100 gives patients a comprehensive health risk assessment and biometric screening. The goal is to empower patients to track their health over time and to learn how their behavior and lifestyle are impacting their health in a very tangible way.

"Journal of Medical Internet Research The leading peer-reviewed journal for digital medicine and health and health care in the internet age"

ABSTRACT Decentralized apps (DApps) are computer programs that run on a distributed computing system, such as a blockchain network. Unlike the client-server architecture that powers most internet apps, DApps that are integrated with a blockchain network can execute app logic that is guaranteed to be transparent, verifiable, and immutable. This new paradigm has a number of unique properties that are attractive to the biomedical and health care communities. However, instructional resources are scarcely available for biomedical software developers to begin building DApps on a blockchain. Such apps require new ways of thinking about how to build, maintain, and deploy software. This tutorial serves as a complete working prototype of a DApp, motivated by a real use case in biomedical research requiring data privacy. We describe the architecture of a DApp, the implementation details of a smart contract, a sample iPhone operating system (iOS) DApp that interacts with the smart contract, and the development tools and libraries necessary to get started. The code necessary to recreate the app is publicly available.

N1: wellness by experiment 17+ Back your wellness with data INGH Available on iOS only You can use this app to join a clinical trial on cognition. Comparing 2 treatments using caffeine (50-400 mg) and caffeine (50-400 mg) in combination with L-theanine (250 mg) : L-theanine is a naturally occurring amino acid most commonly found in green tea. I've downloaded the app will join the study. Interesting screen by screen informed consent process. Will report what I discover at an upcoming Apollo Meeting.

DeAunne Denmark, MD, PhD - Magnificent resource N-of-1 guide An interactive explainer on what N-of-1 is and it's purpose.