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Dennis OConnor

Kundalini Yoga for Post-Treatment Lyme Disease: A Preliminary Randomized Study - PubMed - 0 views

pubmed.ncbi.nlm.nih.gov/35885840

yoga lyme research

shared by Dennis OConnor on 19 Aug 22 - No Cached
  • Dennis OConnor on 19 Aug 22
     
    "Abstract This study examined the adherence to and the potential benefit of Kundalini yoga (KY) for post-treatment Lyme disease syndrome (PTLDS). Participants were randomly assigned to 8 weeks of a KY small-group intervention or a waitlist control (WLC). Adherence was measured as attendance at KY group sessions. Primary outcomes assessed pain, pain interference, fatigue, and global health. Secondary outcomes assessed multisystem symptom burden, mood, sleep, physical and social functioning, cognition, and mindfulness. Linear mixed models were used to test changes in outcomes over time as a function of group assignment; intercepts for participants were modeled as random effects. Although the target sample size was 40 participants, the study concluded with 29 participants due to recruitment challenges. No KY participants dropped out of the study, and participants attended 75% of group sessions on average, but WLC retention was poor (57%). Regarding primary outcomes, there was no significant interaction between group and time. Regarding secondary outcomes, there was a significant interaction between group and time for multisystem symptom burden (p < 0.05) and cognition (p < 0.01); KY participants reported improved multisystem symptom burden and cognition over the course of the study compared to WLC participants. To enhance recruitment and retention, future trials may consider expanding geographic access and including supportive procedures for WLC participants. This preliminary study supports the need for a larger study to determine if KY reduces multisystem symptom burden and enhances cognition among people with PTLDS."
Dennis OConnor

The Chopra Center | Homepage - 0 views

chopra.com

ecosystem

shared by Dennis OConnor on 29 May 18 - Cached
  • Dennis OConnor on 29 May 18
     
    "From life-changing live events and online courses, to eye-opening teacher trainings and unique products, The Chopra Center brings the timeless wisdom of meditation, yoga, and Ayurveda into the modern world. Discover self-awareness and why it is the key to closing the gap between who you are and who you want to be."
Dennis OConnor

Karen Sothers - Mindfulness Based Stress Reduction - 0 views

www.karensothers.com

mindfulness mbsr yoga

shared by Dennis OConnor on 19 Dec 18 - No Cached
  • Dennis OConnor on 19 Dec 18
     
    Karen has been my teacher since 2012. She is a true soul. Bringing her into the circle would be a wise decision.
Dennis OConnor

The Quantification of Placebo Effects Within a General Model of Health Care Outcomes - 1 views

www.ncbi.nlm.nih.gov/...PMC3162378

placebo research positivity

shared by Dennis OConnor on 04 Jul 20 - No Cached
  • It is proposed that the integration of a scientific model of placebo effects within a general model of health care outcomes could finally end the placebo debate and help to integrate these powerful effects into the health care system.
  • Positive expectancy is recognized as a central component of placebo phenomena by all placebo theorists
  • The proposed model emphasizes that the search for a placebo personality factor must be combined with the measurement of situational expectancy.
  • ...47 more annotations...
  • an individual who has negative expectations regarding treatment effectiveness would likely produce a stronger than average “nocebo” effec
  • placebo-prone personality
  • Absorption
  • receptivity to sensory experiences and a propensity for sustained, focused attention.
  • Absorption has a genetic basis and is higher in women compared to men
  • Absorption can go in either a positive or negative direction, depending on the situation,
  • Subjects were randomly
  • outcome measures
  • based on three scales
  • includes scales measuring fatigue, pain, and spasticity
  • Judgment that the placebo was the active device resulted in a positive score with a magnitude of the confidence rating.
  • if judgment was that the placebo was the placebo device, the confidence rating of the placebo was a negative score, with the magnitude of the rating.
  • scored in the upper quintile on improved quality of life, as measured by the 3 QLI (an average of three symptom scales measuring pain, fatigue, and spasticity) after receiving treatment with a sham device.
  • placebo responders
  • Placebo responders scored higher on Absorptio
  • Placebo responders gave higher confidence ratings that the placebo was the active device
  • This study provides support for a two-factor model of placebo responding.
  • importance of positive expectancy
  • both cognitive and emotional factors mediate these effects
  • Positive beliefs or confidence in the treatment coupled with a desire to feel better activate processes that result in positive outcomes.
  • positive expectancy is an essential factor
  • disease-specific pathways that are activated by positive expectancies have helped to transform this “soft” psychologic factor into a “hard” physiologic factor with physically measurable effects.
  • While the shift from negative to positive affect may be the hallmark of placebo responding, negative affect alone is not sufficient and can play a role in people who worsen as well (nocebo effects).
  • Numerous research studies have reliably shown that Absorption is modestly (yet very consistently) correlated with hypnotizability.
  • Hypnotizability is often associated with “suggestibility,” with perhaps the sense of a weak-willed character or unbridled fantasy-proneness, the “unreality factor” that has plagued placebo theory for decades.
  • enlightening to view these individual differences as a natural endowment in self-regulation skills: a potential innate strength rather than a simple weakness with a natural ability for self-directed healing in response to health challenges.
  • Decades of research have reliably demonstrated that individuals scoring high in Absorption can skillfully modulate an impressive array of physiologic processes in laboratory settings.
  • The literature suggests that the mind–body control of high Absorption scorers is similar to the self-regulation skills that many are seeking to develop with meditation, mindfulness, yoga, and qigong.
  • The regular practice of mind–body control and the cultivation of positive attitudes may enhance regulation at higher levels, improving the regularity of circadian and other rhythms,
  • points to the role of both expectation and conditioning, with conditioning playing a greater role in certain pathways such as immune modulation.
  • somatic vulnerability of high Absorption individuals who suffer from negative biases in perception.
  • nocebo phenomena described by these researchers are important for our model as they directly illustrate the power of a negative interaction of the two factors.
  • Many physicians admit to prescribing placebos to contribute to patient wellness, even though this “dark secret” is not condoned and is considered to be ethically questionable.
  • High Absorption individuals may benefit from encouragement to utilize their innate self-regulation skills toward maximum therapeutic effect.
  • ersons with average Absorption scores can be encouraged to become more skilled at self-regulation through mind–body therapies
  • The model does not specifically address the many factors that contribute to confidence in the treatment, such as cost, pill color, pill size, or confidence-enhancing paraphernalia.
  • The role of provider and patient interaction are also not specifically addressed.
  • he model also does not directly address the role of stress reduction
  • The strength of placebo responding in domains such as pain and depression clearly indicate the importance of the shift from a negative to a positive state.
  • the unresolved issue of why some people respond to placebos whereas others do not
  • asic two-factor model can be further tested with the basic measurement tools of expectancy and Absorption,
  • Conclusions
  • the recognition that positive expectancy and expert self-regulation skills significantly contribute to health outcomes can help to integrate these powerful effects into the health care system
  • The “positive psychology” movement is shifting attention to the power of positive expectation
  • undermining nature of negative expectancy and pessimistic language, especially in vulnerable populations such as those with pain and depression
  • Practitioners of the art of health care have always recognized the importance of motivated and empowered patients and the power of a kind word and a ray of hope.
  • This is the time to quantify these factors, integrating art and science, and finally solving (and forgiving Descartes for) the mind–body problem.
  • Dennis OConnor on 04 Jul 20
     
    "The topic of placebo effects is distinguished by decades of keen scientific interest1-4 coupled with a general skepticism regarding the ultimate significance of these phenomena. The importance of psychologic factors in mediating these effects may contribute to the attitude that placebo effects are not as substantial as a therapeutic effect produced by a drug. Complementary and alternative therapies have sometimes been dismissed as "mere placebos." However, recent studies have provided compelling evidence that placebo effects are physiologically measurable with condition-specific pathways.5"
  • Dennis OConnor on 04 Jul 20
     
    Dr. Jake Fleming recently suggested these potent keywords: quantifiable placebo The keywords led to this article. I find it affirming and empowering.
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