Skip to main content

Home/ PHE - Resources/ Group items tagged long-covid

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Dennis OConnor

Persistent Symptoms in Patients After Acute COVID-19 | Critical Care Medicine | JAMA | ... - 0 views

jamanetwork.com/...2768351

covid research pandemic

shared by Dennis OConnor on 05 Aug 20 - No Cached
  • Dennis OConnor on 05 Aug 20
     
    "Discussion This study found that in patients who had recovered from COVID-19, 87.4% reported persistence of at least 1 symptom, particularly fatigue and dyspnea. Limitations of the study include the lack of information on symptom history before acute COVID-19 illness and the lack of details on symptom severity. Furthermore, this is a single-center study with a relatively small number of patients and without a control group of patients discharged for other reasons. Patients with community-acquired pneumonia can also have persistent symptoms, suggesting that these findings may not be exclusive to COVID-19.6 Clinicians and researchers have focused on the acute phase of COVID-19, but continued monitoring after discharge for long-lasting effects is needed."
Dennis OConnor

Visualizing the Long Covid experience | by Katie McCurdy | Jul, 2022 | Medium - 0 views

medium.com/...-covid-experience-f0d20e5f3ecd

covid data visualization

shared by Dennis OConnor on 23 Jul 22 - No Cached
  • Dennis OConnor on 23 Jul 22
     
    "As a highly allergic and reactive person with multiple autoimmune conditions, I am likely at risk for Long Covid. I've closely followed the news about this mysterious and pervasive new condition and read about its debilitating symptoms. But until now, I hadn't personally known anyone with Long Covid."
Dennis OConnor

In the coronavirus pandemic, we're making decisions without reliable data - 4 views

www.statnews.com/...ecisions-without-reliable-data

covid testing research pandemic data

shared by Dennis OConnor on 19 Mar 20 - No Cached
  • A fiasco in the making? As the coronavirus pandemic takes hold, we are making decisions without reliable data
  • This evidence fiasco creates tremendous uncertainty about the risk of dying from Covid-19.
  • As most health systems have limited testing capacity, selection bias may even worsen in the near future.
  • ...8 more annotations...
  • The one situation where an entire, closed population was tested was the Diamond Princess cruise ship and its quarantine passengers. The case fatality rate there was 1.0%, but this was a largely elderly population, in which the death rate from Covid-19 is much higher.
  • Projecting the Diamond Princess mortality rate onto the age structure of the U.S. population, the death rate among people infected with Covid-19 would be 0.125%. But since this estimate is based on extremely thin data — there were just seven deaths among the 700 infected passengers and crew — the real death rate could stretch from five times lower (0.025%) to five times higher (0.625%).
  • Although successful surveillance systems have long existed for influenza, the disease is confirmed by a laboratory in a tiny minority of cases.
  • Some worry that the 68 deaths from Covid-19 in the U.S. as of March 1610 will increase exponentially to 680, 6,800, 68,000, 680,000 … along with similar catastrophic patterns around the globe. Is that a realistic scenario, or bad science fiction? How can we tell at what point such a curve might stop?
  • In the absence of data, prepare-for-the-worst reasoning leads to extreme measures of social distancing and lockdowns.
  • This has been the perspective behind the different stance of the United Kingdom keeping schools open12, at least until as I write this. In the absence of data on the real course of the epidemic, we don’t know whether this perspective was brilliant or catastrophic.
  • One of the bottom lines is that we don’t know how long social distancing measures and lockdowns can be maintained without major consequences to the economy, society, and mental health.
  • At a minimum, we need unbiased prevalence and incidence data for the evolving infectious load to guide decision-making.
  • Dennis OConnor on 19 Mar 20
     
    Dr. Michael Kurisu D.O. "My take is this article is written by a very credible source. John P.A. Ioannidis is from Stanford and great resource. Makes argument that we are basing a LOT of our decisions on faulty or NO data ! Its fascinating to me that there has been less than 10,000 deaths globally and we have had SO MUCH DISRUPTION in the economy. I definitely feel we should be tracking the amount of deaths that are going to occur from people that will be pushed into poverty as well as the number of people being denied access to medical care right now. Yes… with COVID19, it CAN get much worse…. But maybe not… we don't know yet. This article actually increased my morale and put me on track to help GET MORE DATA. Then we can make informed decisions. And then TRACK ALL THE DATA moving forward.
  • Dennis OConnor on 19 Mar 20
     
    DeAunne Denmark, MD, PhD, "Excellent piece spelling out the pervasive and critical issues due to abysmal lack/tardiness in US testing, especially of large populations where initial outbreaks occurred, for those both visibly sick and not. And most importantly, healthcare workers. We cannot even begin to estimate CFR, much less develop reliable projection models, without valid data on everybody who is carrying. "The most valuable piece of information for answering those questions would be to know the current prevalence of the infection in a random sample of a population and to repeat this exercise at regular time intervals to estimate the incidence of new infections."
Dennis OConnor

Breakthrough Infections in Vaccinated People Less Likely to Cause 'Long COVID' - NIH Di... - 0 views

directorsblog.nih.gov/...ess-likely-to-cause-long-covid

covid

shared by Dennis OConnor on 15 Sep 21 - No Cached
  • Dennis OConnor on 15 Sep 21
     
    "Breakthrough Infections in Vaccinated People Less Likely to Cause 'Long COVID'"
Dennis OConnor

Coronavirus Will Change the World Permanently. Here's How. - POLITICO - 0 views

www.politico.com/...-society-analysis-covid-135579

future disruption covid

shared by Dennis OConnor on 28 Mar 20 - No Cached
  • Instead of asking, “Is there a reason to do this online?” we’ll be asking, “Is there any good reason to do this in person?”
  • saluting our doctors and nurses, genuflecting and saying, “Thank you for your service,”
  • give them guaranteed health benefits and corporate discounts
  • ...131 more annotations...
  • it will force us to reconsider who we are and what we value, and, in the long run, it could help us rediscover the better version of ourselves.
  • has the potential to break America out of the 50-plus year pattern of escalating political and cultural polarization
  • the “common enemy” scenario, in which people begin to look past their differences when faced with a shared external threat
  • second reason is the “political shock wave” scenario
  • enduring relational patterns often become more susceptible to change after some type of major shock destabilizes them
  • now is the time to begin to promote more constructive patterns in our cultural and political discourse. The time for change is clearly ripening.
  • The COVID-19 crisis
  • has already forced people back to accepting that expertise matters.
  • move them back toward the idea that government is a matter for serious people.
  • the end of our romance with market society and hyper-individualism.
  • We could turn toward authoritarianism
  • reorient our politics and make substantial new investments in public goods—for health, especially—and public services.
  • to allowing partial homeschooling or online learning for K-12 kids has been swept away by necessity.
  • the social order it helps support—will collapse if the government doesn’t guarantee income for the millions of workers who will lose their jobs in a major recession or depression
  • de-militarization of American patriotism and love of community will be one of the benefits to come out of this whole awful mess.
  • But how do an Easter people observe their holiest day if they cannot rejoice together on Easter morning?
  • How do Jews celebrate their deliverance from bondage when Passover Seders must take place on Zoom
  • Can Muslim families celebrate Ramadan if they cannot visit local mosques for Tarawih prayers
  • All faiths have dealt with the challenge of keeping faith alive under the adverse conditions of war or diaspora or persecution—but never all faiths at the same time.
  • Contemplative practices may gain popularity
  • One group of Americans has lived through a transformational epidemic in recent memory: gay men. Of course, HIV/AIDS
  • Plagues drive change.
  • awakened us to the need for the protection of marriage
  • People are finding new ways to connect and support each other in adversity
  • demand major changes in the health-care system
  • COVID-19 will sweep away many of the artificial barriers to moving more of our lives online
  • uptake on genuinely useful online tools has been slowed by powerful legacy players,
  • collaboration with overcautious bureaucrats
  • Medicare allowing billing for telemedicine was a long-overdue change
  • s was revisiting HIPAA to permit more medical providers to use the same tools the rest of us use every day to communicate, such as Skype, Facetime and email.
  • The resistance
  • we will be better able to see how our fates are linked.
  • near-impossible to put that genie back in the bottle in the fall
  • college
  • forcing massive changes in a sector that has been ripe for innovation for a long time.
  • Once companies sort out their remote work dance steps, it will be harder—and more expensive—to deny employees those options.
  • Yo-Yo Ma
  • Perhaps we can use our time with our devices to rethink the kinds of community we can create through them
  • This is a different life on the screen from disappearing into a video game or polishing one’s avatar.
  • breaking open a medium with human generosity and empathy
  • Not only alone together, but together alone.
  • The rise of telemedicine
  • Out of necessity, remote office visits could skyrocket in popularity as traditional-care settings are overwhelmed by the pandemic
  • they’ve been forced to make impossible choices among their families, their health and financial ruin.
  • This crisis should unleash widespread political support for Universal Family Care
  • single public federal fund that we all contribute to, that we all benefit from, that helps us take care of our families while we work, from child care and elder care to support for people with disabilities and paid family leave.
  • potlight on unmet needs of the growing older population
  • The reality of fragile supply chains for active pharmaceutical ingredients coupled with public outrage over patent abuses that limit the availability of new treatments has led to an emerging, bipartisan consensus that the public sector must take far more active and direct responsibility for the development and manufacture of medicines.
  • resilient government approach will replace our failed, 40-year experiment with market-based incentives
  • Science reigns again.
  • Truth and its most popular emissary, science, have been declining in credibility for more than a generation
  • Quickly, however, Americans are being reacquainted with scientific concepts like germ theory and exponential growth
  • Unlike with tobacco use or climate change, science doubters will be able to see the impacts of the coronavirus immediately
  • for the next 35 years, I think we can expect that public respect for expertise in public health and epidemics to be at least partially restored
  • Congress can finally go virtual.
  • We need Congress to continue working through this crisis, but given advice to limit gatherings to 10 people or fewer, meeting on the floor of the House of Representatives is not an especially wise option right now
  • nstead, this is a great time for congresspeople to return to their districts and start the process of virtual legislating—permanently
  • Lawmakers will be closer to the voters they represent
  • sensitive to local perspectives and issues
  • A virtual Congress is harder to lobby
  • Party conformity also might loosen with representatives remembering local loyalties over party ties.
  • Big government makes a comeback.
  • Not only will America need a massive dose of big government
  • we will need big, and wise, government more than ever in its aftermath.
  • The widely accepted idea that government is inherently bad won’t persist after coronavirus.
  • functioning government is crucial for a healthy society
  • most people are desperately hoping
  • a rebirth of the patriotic honor of working for the government.
  • the coronavirus crisis might sow the seeds of a new civic federalism, in which states and localities become centers of justice, solidarity and far-sighted democratic problem-solving.
  • we will see that some communities handled the crisis much better than others.
  • success came in states where government, civic and private-sector leaders joined their strengths together in a spirit of self-sacrifice for the common good.
  • The coronavirus is this century’s most urgent challenge to humanity.
  • a new sense of solidarity, citizens of states
  • The rules we’ve lived by won’t all apply
  • pandemic has revealed a simple truth:
  • many policies that our elected officials have long told us were impossible and impractical were eminently possible and practical all along.
  • student loans and medical debt
  • evictions were avoidable; the homeless could’ve been housed
  • Trump has already put a freeze on interest for federal student loans
  • Governor Andrew Cuomo has paused all medical and student debt owed to New York State
  • Democrats and Republicans are discussing suspending collection on—or outright canceling—student loans as part of a larger economic stimulus package
  • It’s clear that in a crisis, the rules don’t apply
  • an unprecedented opportunity to not just hit the pause button and temporarily ease the pain, but to permanently change the rules so that untold millions of people aren’t so vulnerable to begin with.
  • Revived trust in institutions.
  • oronavirus pandemic, one hopes, will jolt Americans into a realization that the institutions and values Donald Trump has spent his presidency assailing are essential to the functioning of a democracy—and to its ability to grapple effectively with a national crisis.
  • government institutions
  • need to be staffed with experts (not political loyalists),
  • decisions need to be made through a reasoned policy process and predicated on evidence-based science and historical and geopolitical knowledge
  • we need to return to multilateral diplomacy,
  • to the understanding that co-operation with allies—and adversaries, too—is especially necessary when it comes to dealing with global problems like climate change and viral pandemics.
  • t public trust is crucial to governance
  • 1918 flu pandemic
  • the main lesson from that catastrophe is that “those in authority must retain the public’s trust” and “the way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one.”
  • Expect a political uprising.
  • Occupy Wall Street 2.0, but this time much more massive and angrier.
  • Electronic voting goes mainstream.
  • how to allow for safe voting in the midst of a pandemic, the adoption of more advanced technology
  • To be clear, proven technologies now exist that offer mobile, at-home voting while still generating paper ballots.
  • This system is not an idea; it is a reality that has been used in more than 1,000 elections for nearly a decade by our overseas military and disabled voters.
  • hould be the new normal.
  • Election Day will become Election Month.
  • The change will come through expanded early voting and no-excuse mail-in balloting, effectively turning Election Day into Election Month
  • Once citizens experience the convenience of early voting and/or voting by mail, they won’t want to give it up.
  • . Some states, such as Washington, Oregon and Utah, already let everyone vote at home.
  • Voters already receive registration cards and elections guides by mail. Why not ballots?
  • First, every eligible voter should be mailed a ballot and a self-sealing return envelope with prepaid postage.
  • Elections administrators should receive extra resources to recruit younger poll workers, to ensure their and in-person voters’ health and safety, and to expand capacity to quickly and accurately process what will likely be an unprecedented volume of mail-in votes.
  • In the best-case scenario, the trauma of the pandemic will force society to accept restraints on mass consumer culture as a reasonable price to pay to defend ourselves against future contagions and climate disasters alike.
  • In the years ahead, however, expect to see more support from Democrats, Republicans, academics and diplomats for the notion that government has a much bigger role to play in creating adequate redundancy in supply chains—resilient even to trade shocks from allies. This will be a substantial reorientation from even the very recent past.
  • pressure on corporations to weigh the efficiency and costs/benefits of a globalized supply chain system against the robustness of a domestic-based supply chain.
  • other gap that has grown is between the top fifth and all the rest—and that gap will be exacerbated by this crisis.
  • In this crisis, most will earn steady incomes while having necessities delivered to their front doors.
  • other 80 percent of Americans lack that financial cushion.
  • will struggle
  • A hunger for diversion.
  • After the disastrous 1918-19 Spanish flu and the end of World War I, many Americans sought carefree entertainment, which the introduction of cars and the radio facilitated.
  • The economy quickly rebounded and flourished for about 10 years, until irrational investment tilted the United States and the world into the Great Depression.
  • human beings will respond with the same sense of relief and a search for community, relief from stress and pleasure.
  • Less communal dining—but maybe more cooking
  • many people will learn or relearn how to cook over the next weeks.
  • ikely there will be many fewer sit-down restaurants in Europe and the United States. We will be less communal at least for a while.
  • A revival of parks.
  • Urban parks—in which most major cities have made significant investments over the past decade—are big enough to accommodate both crowds and social distancing.
  • Society might come out of the pandemic valuing these big spaces even more,
  • A change in our understanding of ‘change.’
  • Americans have said goodbye to a society of frivolity and ceaseless activity in a flash
  • Our collective notions of the possible have changed already
  • The tyranny of habit no more.
  • Maybe, as in Camus’ time, it will take the dual specters of autocracy and disease to get us to listen to our common sense, our imaginations, our eccentricities—and not our programming.
  • and environmentally and physiologically devastating behaviors (including our favorites: driving cars, eating meat, burning electricity)
  • echarged commitment to a closer-to-the-bone worldview that recognizes we have a short time on earth
Dennis OConnor

Predicting 'Long COVID Syndrome' with Help of a Smartphone App - NIH Director's Blog - 0 views

directorsblog.nih.gov/...-with-help-of-a-smartphone-app

covid-19 long-covid research apps

shared by Dennis OConnor on 23 Mar 21 - No Cached
  • Dennis OConnor on 23 Mar 21
     
    Recommended by Tyler Orion, Endorsed by DeAunne Denmark, MD, PhD :This is an example of the high quality and thoughtful study design needed to accurately and meaningfully interpret real-world tracking data. This prediction signal would not have been detected in the larger (inconsistently reporting) group, or in those who hadn't tracked enough before getting sick. Which relates to the importance of creating a baseline health timeline and consistently collecting robust, standardized pre-intervention contextual data. And another illustration re: why I keep circling back to these in all of our n-of-1 discussions :)
Dennis OConnor

What The 1918 Flu Pandemic Can Tell Us About The COVID-19 Crisis : NPR - 0 views

www.npr.org/...l-us-about-the-covid-19-crisis

covid pandemic

shared by Dennis OConnor on 05 Aug 20 - No Cached
  • Dennis OConnor on 05 Aug 20
     
    "John Barry, author of the 2004 book, The Great Influenza, draws parallels between today's pandemic and the flu of 1918. In both cases, he says, "the outbreak was trivialized for a long time.""
Dennis OConnor

Covid-19 "long haulers" are organizing online to study themselves | MIT Technology Review - 0 views

www.technologyreview.com/...ing-online-to-study-themselves

covid research citizen-science self-study

shared by Dennis OConnor on 21 Aug 20 - No Cached
  • Dennis OConnor on 21 Aug 20
     
    "Slack groups and social media are connecting people who've never fully recovered from coronavirus to collect data on their condition."
Dennis OConnor

Crash Course | Snyder Lab Studies - Genetics - Stanford University School of Medicine - 0 views

snyderlabs.stanford.edu/crashcourse

lyme-disease research covid

shared by Dennis OConnor on 20 Oct 21 - No Cached
  • Dennis OConnor on 20 Oct 21
     
    Recommended"Stanford University researchers are recruiting ME/CFS, Chronic Lyme, and Long COVID patients for a study to better understand symptom flares such as post-exertional malaise (PEM), or "crashes"."
Dennis OConnor

Long-Haulers Are Redefining COVID-19 - The Atlantic - 2 views

www.theatlantic.com/...615382

patient-centered research data

shared by Dennis OConnor on 21 Aug 20 - No Cached
  • Dennis OConnor on 21 Aug 20
     
    "Without clear information from official sources, many long-haulers have found answers from one another. Support groups on Facebook have thousands of members. One Slack group, founded within a wellness organization called Body Politic, has almost doubled in size since June to more than 7,000 active participants from 25 countries. There are channels for discussing every organ system in the body. There are lists of sympathetic medical providers, and tips for convincing those who aren't listening. Eerily, the group's membership morphs as the pandemic spreads: "When Brazil had a huge spike, we had a massive influx of Brazilian patients," said Nichols, who is an administrator."
Dennis OConnor

Everything we know about coronavirus immunity, and plenty we still don't - 0 views

www.statnews.com/...odies-and-plenty-we-still-dont

covid testing antibodies

shared by Dennis OConnor on 20 Apr 20 - No Cached
  • an accurate positive test may be hard to interpret: the virus is so new that researchers cannot say for sure what sort of results will signal immunity or how long that armor will last.
  • policymakers may be making sweeping economic and social decisions — plans to reopen businesses or schools, for example — based on limited data, assumptions, and what’s known about other viruses.
  • most experts do think an initial infection from the coronavirus, called SARS-CoV-2, will grant people immunity to the virus for some amount of time.
  • ...1 more annotation...
  • With data limited, “sometimes you have to act on a historical basis,” Anthony Fauci,
  • Dennis OConnor on 20 Apr 20
     
    Recommended by Tyler Orion: "People who think they've been exposed to the novel coronavirus are clamoring for antibody tests - blood screens that can detect who has previously been infected and, the hope is, signal who is protected from another case of Covid-19."
Dennis OConnor

This Is How We Beat the Coronavirus - The Atlantic - 1 views

www.theatlantic.com/...608389

covid testing research

shared by Dennis OConnor on 20 Mar 20 - No Cached
  • We’re closing schools and businesses and committing to social (really, physical) distancing. But as the sobering charts from the analysis show, this isn’t enough.
  • Asian countries have engaged in suppression; we are only engaging in mitigation.
  • At the moment, we can’t even test everyone who is sick.
  • ...15 more annotations...
  • Testing will allow us to isolate the infected so they can’t infect others. We need to be vigilant, and willing to quarantine people with absolute diligence.
  • To achieve this, we need to test many, many people, even those without symptoms.
  • buried in the Imperial College report is reason for optimism. The analysis finds that in the do-nothing scenario, many people die and die quickly. With serious mitigation, though, many of the measures we’re taking now slow things down. By the summer, the report calculates, the number of people who become sick will eventually reduce to a trickle.
  • Our efforts are good, temporizing measures.
  • Social distancing cannot prevent these infections, as they’ve already happened. Therefore, things will appear to get worse for some time, even if what we’re doing is making things better in the long run.
  • Our primary approach is social distancing—asking people to stay away from one another.
  • We can create a third path. We can decide to meet this challenge head-on. It is absolutely within our capacity to do so. We could develop tests that are fast, reliable, and ubiquitous. If we screen everyone, and do so regularly, we can let most people return to a more normal life. We can reopen schools and places where people gather. If we can be assured that the people who congregate aren’t infectious, they can socialize.
  • We can build health-care facilities that do rapid screening and care for people who are infected, apart from those who are not.
  • We can even commit to housing infected people apart from their healthy family members, to prevent transmission in households.
  • We will need to massively strengthen our medical infrastructure. We will need to build ventilators and add hospital beds. We will need to train and redistribute physicians, nurses, and respiratory therapists to where they are most needed. We will need to focus our factories on turning out the protective equipment—masks, gloves, gowns, and so forth—to ensure we keep our health-care workforce safe.
  • most importantly, we need to pour vast sums of intellectual and financial resources into developing a vaccine that would finally bring this nightmare to a close
  • If we commit to social distancing, however, at some point in the next few months the rate of spread will slow. We’ll be able to catch our breath. We’ll be able to ease restrictions, as some early hit countries are doing. We can move toward some semblance of normalcy.
  • The temptation then will be to think we have made it past the worst. We cannot give in to that temptation. That will be the time to redouble our efforts. We will need to prepare for the coming storm. We’ll need to build up our stockpiles, create strategies, and get ready.
  • We need to keep time on the clock, time to find a treatment or a vaccine.
  • We all have a choice to make. We can look at the coming fire and let it burn. We can hunker down, and hope to wait it out—or we can work together to get through it with as little damage as possible.
Dennis OConnor

Advice from Dr. Mimi Guarneri - Integrative Medicine - 1 views

www.facebook.com/...1728581947283499

covid containment wellness

shared by Dennis OConnor on 17 Mar 20 - No Cached
  • Dennis OConnor on 17 Mar 20
     
    "Thankfully, there are many things we can do as individuals and communities that may be helpful. It is important to remain calm and think clearly. Remember that our positive attitudes go a long way in protecting health, enriching our daily lives, and supporting the ones we love. Here is a list of things one can do at home to help in these uncertain times:"
1 - 13 of 13
Showing 20▼ items per page