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Discover more types of non-Mendelian inheritance such as incomplete dominance and codominance with the Amoeba Sisters! This video uses vocabulary that was previously defined in the Amoeba Sisters Monohybrid Crosses video.

Explore inheritance when carried on the X chromosome with the Amoeba Sisters!

11 video Hank brings us the story of Gregor Mendel, the Austrian monk who, with the help of a garden full of pea plants, discovered the fundamental properties of inheritance and paved the way for modern genetics. He also gives us the dirt on a scientific scandal that has followed Mendel beyond the grave.

There are a significant number of genetics curriculum resources designed by different companies, curriculum development outlets, state curriculum designers and individual teachers. What resources are good? How do you know? As part of the Geneticist-Educator Network of Alliances (GENA) Project, a Curriculum Content Review Committee was formed to review readily available classroom resources about patterns of inheritance. Click here to see original evaluation form used by the committee and here to see the summary of the committee's review.

When babies are born, their eyes and hair are one color, but change within the first few years of their life! Why do hair and eye colors change? Trace explains the process of inheriting certain traits from your parents, and discusses why the colors change!

Curricular resources including animations and games

By then, researchers had identified three genetic mutations that can be inherited and, if they are, cause a form of Alzheimer's called early onset because it strikes before age 65 and sometimes far earlier. Since 2004, Hornstein and all five of her siblings have been tested. Hornstein is the only one who doesn't carry PSEN1, one of the mutations.

The team was grafting skin from one strain of mice to another. The new skin tended to get destroyed by the recipient animals' immune systems. But when the group injected cells from the donor mice into developing fetuses, the mice that were born were much more likely to accept the skin graft. It seemed they had been primed to the foreign cells while in the womb, and developed a tolerance.

Even if you look like your mother, an innovative study suggests that not only humans but, in fact, all mammals are genetically more like Dad. We inherit equal amounts of genetic material from each parent, yet that coming from our father's side is more likely to take action, according to the study that was published in the journal Nature Genetics.

That's why a paper published Thursday in the journal Genetics in Medicine is so remarkable. The paper identifies NGLY1 deficiency as an inherited genetic disorder, caused by mutations in the NGLY1 gene. The researchers have confirmed eight patients with these mutations who share several symptoms, including developmental delays, abnormal tear production and liver disease.

The Y chromosome is only one-third the size of the X. Although the Y has a partner in X, only the tips of these chromosomes are able to recombine. Thus, most of the Y chromosome is inherited from father to son in a pattern resembling asexual, not sexual, reproduction. No recombination means no reassortment, so deleterious mutations have no opportunity to be independently selected against. The Y chromosome therefore tends to accumulate changes and deletions faster than the X. Degradation doesn't occur in X chromosomes because during female meiosis, the X has the other X as a full partner in recombination.

If the lab technique works in the field, it could offer a new way of stopping the biting insects from spreading malaria to humans, they say. The scientists put a new "resistance" gene into the mosquito's own DNA, using a gene editing method called Crispr. And when the GM mosquitoes mated - their offspring inherited the same resistance, PNAS journal reports. In theory, if these mosquitoes bite people, they should not be able to pass on the parasite that causes malaria.

This biomarker, called the KRAS-variant, is linked to more cancers than any other known inherited genetic mutation. It is present in 1 out of every 4 people with cancer, and in more than half of people who develop multiple cancers. KRAS-variant carriers tend to get highly aggressive and recurrent breast, ovarian, head and neck, lung and pancreatic cancers.

High heritability points to a major role for inherited genetic variants in the aetiology of schizophrenia7, 8. Although risk variants range in frequency from common to extremely rare9, estimates10, 11 suggest half to a third of the genetic risk of schizophrenia is indexed by common alleles genotyped by current genome-wide association study (GWAS) arrays. Thus, GWAS is potentially an important tool for understanding the biological underpinnings of schizophrenia

"This modular case study tells the story of Dan and Annie, a married couple of Acadian ancestry who have a genetic form of deafblindness called Usher syndrome. They live in Southwest Louisiana, home of the largest population of DeafBlind citizens in the United States. Acadian Usher syndrome is caused by an allele of the USH1C gene that came to Louisiana with the first Acadian settlers from Canada who founded today's Cajun population. This allele's single nucleotide substitution creates an erroneous splice site that produces a defective cytoskeletal protein (harmonin) of the cochlear and vestibular hair cells and retinal photoreceptors. This splice site is the target of a promising gene therapy. The case study applies and connects Mendelian inheritance, chromosomes, cell division, vision and hearing, DNA sequences, gene expression, gene therapy and population genetics to a specific gene and its movement through generations of Dan and Annie's families.  After the introduction, each of the remaining sections can be used independently either for in-class team activities or out-of-class extensions or assignments over an entire year of introductory undergraduate biology. "

Review of many examples of epigenetics and mechanisms. Discussion incorporates evolution.

Rat-smell-fear epigenetic summary in cartoons

This PowerPoint-driven, flipped case study begins with a short video about a woman suffering from cystic fibrosis (CF) in the 1970s, a friend of the lead author's, whom she met in college and who died in her twenties. Hooked by this personal story, students then delve into the genetics and biology of cystic fibrosis as they learn about the difference between dominant and recessive genes, make Punnett squares that depict various types of inheritance, distinguish between probability and actual numbers, differentiate types of mutations, and learn about the opportunistic infections that CF patients often succumb to.  Students conclude the case by watching two additional videos on chest compression machines and the contemporary life expectancy of patients with CF.  In addition to the scientific content presented in the case, it is hoped that students will empathize with, and be motivated by, the young people presented in the videos as they struggle with a very real, incurable disease deeply rooted in genetics.

Hereditary methemoglobinemia (met-H) is a human genetic disease that is inherited as an autosomal recessive.

Interactive genetics site.  Straight forward games based on Punnett squares using bunny families.