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The worst cancer cells don't sit still. Instead they metastasize-migrate from their original sites and establish new tumors in other parts of the body. Once a cancer spreads, it is harder to eliminate. A study by developmental biologists offers a fresh clue to how cancer cells acquire the ability to invade other tissues-a prerequisite for metastasis. It reveals that invasion requires cells to stop dividing. Therefore, the two processes- invasion and proliferation-are mutually exclusive. The finding could inform cancer therapies, which typically target rapidly proliferating cancer cells.

Millions of people in 70 countries across Asia, Africa, and South America have been exposed to high levels of mercury as small-scale mining has proliferated over the past decade. The United Nations Environment Programme estimates that at least 10 million miners, including at least four million women and children, are working in small "artisanal" gold mines, which produce as much as 15 percent of the world's gold.

Part 2 of 2. David Attenborough explains how early sea life developed and adapted to dry land, becoming Reptiles and Amphibians. After the era of the Dinosaurs came to a sudden end, Mammal species began to proliferate. From BBC 1 documentary 'Charles Darwin and the Tree of Life'.

This clicker case was designed to teach students about basic enzyme structure, mechanisms of enzyme inhibition, and mechanisms of drug resistance. The story follows Oliver Casey, a patient afflicted with Chronic Myelogenous Leukemia (CML). CML is caused by a chromosomal mutation that affects the tyrosine kinase ABL, an enzyme important in regulating cell growth and proliferation. The chromosomal mutation gives rise to the BCR-ABL fusion gene that produces a constitutively active ABL kinase, which causes the leukemia. In May 2001, the Food and Drug Administration approved the use of a rationally designed tyrosine kinase inhibitor, imatinib (Gleevec®), for the treatment of CML. During that same month, Gleevec made the cover of TIME magazine, described as "new ammunition in the war on cancer." The case is structured for a flipped classroom environment in which students view preparatory videos (including one by the author) on their own before beginning the case. Written for a first-year introductory biology course, the case could also be adapted for AP/Honors high school biology or a cancer biology course.

Multiple outbreaks have been reported in poultry farms and wild flocks across Europe, Africa and Asia in the past three months. While most involve strains that are currently low risk for human health, the sheer number of different types, and their presence in so many parts of the world at the same time, increases the risk of viruses mixing and mutating - and possibly jumping to people.