In this video segment from NOVA: "Cracking the Code of Life," Eric Lander of MIT's Whitehead Institute explains the effort to decode the human genome -- from motivation to process to importance -- and explains what a genome map can do for science and what it can't -- yet.
With a dozen or so 140-character dispatches (including three heat maps), Gilad suggested the results published in PNAS were an anomaly-a result of how the tissue samples were sequenced in different batches. If this "batch effect" was eliminated, he proposed, mouse and human tissues clustered in a tissue-specific manner, confirming previous results rather than supporting the conclusions reported by the Mouse ENCODE team.
Dogs are excellent models for studying genetics, especially disease genetics. Work done in the last 20 years has shown that dogs share many gene-related disorders with people. Each breed is a closed reproductive population with distinct rates of heritable diseases, which dramatically increases the odds of finding disease-related loci. In creating new dog breeds, we reduce the gene pool within those populations, and fix many alleles. This homogeneous background makes it much easier to map QTLs and perform linkage analyses
he National Agricultural Literacy Curriculum Matrix is an online, searchable, and standards-based curriculum map for K-12 teachers. The Matrix contextualizes national education standards in science, social studies, and nutrition education with relevant instructional resources linked to Common Core Standards. Search our instructional, classroom-ready resources now! After you find what you need, consider storing them in your personal binder - MyBinder!
This activity supports the HHMI short film The Origin of Species: The Making of a Theory. Students are presented with a map of the Malay Archipelago and some field notebooks with observations of animals. By plotting which animals are found on which island, the students discover the Wallace Line-a sharp boundary that separates distinct Asian and Australian fauna.
Sheep ranching has destroyed habitat and decimated species in many areas of the world, but in Patagonia declining wool prices provide an opportunity to turn the tide. This case study places students in the role of advisor to an international NGO that has funds to advance conservation goals. A PowerPoint slideshow is used to present the Patagonian landscape, species, and variables that should be considered in conservation decisions. After the presentation, students are given two maps: the first shows park boundaries, topography, roads, and major land forms; the second includes land prices overlaid on the first. Student groups are assigned a budget, and with the help of a set of guiding questions, students identify and defend a potential land purchase to develop as a protected area. The case is intended for use in an undergraduate class in conservation biology, environmental science or ecology, and presupposes another case in our collection, "The Great Patagonia Land Grab" by C.E. Quinn and J.E. Quinn
This interactive case discussion was created to emphasize the clinical relevance of population genetics, but is also a suitable resource for teaching the basic principles of population genetics while relating them to human genetic variation. Our understanding of human genetic variation has deepened over the past decade due to fine-scale genome mapping. Applying this knowledge to the evaluation of ancestry-based genetic testing strategies, such as direct-to-consumer genetic testing, is an important component of the practice of culturally-competent medicine and a relevant way to teach the foundations of population genetics, including Hardy-Weinberg equilibrium.
As you read the chapters in Stiff, attach a post-it note to pages where you highlight something interesting. You should have 4-10 Post-It's per chapter, use the following symbol guide to create your notes. Stiff has 12 chapters, you are only required to map (Post-It) 8 of those chapters. You are welcome to read them all, of course, but you can also choose to focus on chapters that interest you the most or skip those you do not find interesting. You may wish to skim the chapters or browse the table of contents.
Each Post-It will contain three items
1. Symbol (see chart)
2. Page and paragraph number
3. Content
How can a mixture of molecules, too small to be seen with even a high-powered microscope, be separated from one another? Such was the dilemma facing scientists until the development of a process that is now standard in laboratories worldwide-gel electrophoresis. Laboratories rely heavily on this proven and reliable technique for separating a wide variety of samples, from DNA used in forensics and for mapping genes, to proteins useful in determining evolutionary relationships.
To understand the importance of elements to nutrition.
Of the approximately 115 elements known, only the 19 highlighted in purple in Figure 1.26 are absolutely required in the human diet. These elements-called essential elements-are restricted to the first four rows of the periodic table (see Chapter 32 "Appendix H: Periodic Table of Elements"), with only two or three exceptions (molybdenum, iodine, and possibly tin in the fifth row). Some other elements are essential for specific organisms. For example, boron is required for the growth of certain plants, bromine is widely distributed in marine organisms, and tungsten is necessary for some microorganisms.
The first activity will have you investigate some of the animals in the Mexican ecosystem. Figure out who are the predators and who are their prey and build your own food web.
A worldwide study of the DNA of 100,000 women has discovered two new genetic variants associated with an increased risk of breast cancer.
The genetic variants are specifically linked to the most common form of breast cancer, oestrogen receptor positive, and provide important insights into how the disease develops.
BodyMaps is an interactive visual search tool that allows users to explore the human body in 3-D. With easy-to-use navigation, users can search multiple layers of the human anatomy, view systems and organs down to their smallest parts, and understand in detail how the human body works.
Using detailed 3-D models of body parts-including muscles, veins, bones, and organs-BodyMaps offers a new way to visualize and manage your health. See how the coronary artery delivers blood to the heart, and learn how plaque build-up on artery walls leads to heart disease. Locate the exact location of a pulled muscle or broken bone, and find information on how to prevent injuries. View a cross-section of the human brain, and learn which areas control certain emotions and body functions.
By offering rich, detailed anatomical images alongside links to relevant and useful health information, BodyMaps allows you to leam about your body and your health in a personalized and revolutionary new way.