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The box plot (a.k.a. box and whisker diagram) is a standardized way of displaying the distribution of data based on the five number summary: minimum, first quartile, median, third quartile, and maximum. In the simplest box plot the central rectangle spans the first quartile to the third quartile (the interquartile range or IQR). A segment inside the rectangle shows the median and "whiskers" above and below the box show the locations of the minimum and maximum.

To understand the importance of elements to nutrition. Of the approximately 115 elements known, only the 19 highlighted in purple in Figure 1.26 are absolutely required in the human diet. These elements-called essential elements-are restricted to the first four rows of the periodic table (see Chapter 32 "Appendix H: Periodic Table of Elements"), with only two or three exceptions (molybdenum, iodine, and possibly tin in the fifth row). Some other elements are essential for specific organisms. For example, boron is required for the growth of certain plants, bromine is widely distributed in marine organisms, and tungsten is necessary for some microorganisms.

This case study is centered on a real scenario from 2013 in which the Kickstarter fundraising platform included a fundraising proposal from a group wanting to use synthetic biology to make glowing plants. The proposal raised controversy because the Glowing Plant group offered to give away their genetically-modified glowing plant product to investors.  Kickstarter subsequently changed its policy to prevent use of genetically modified organisms as rewards or incentives to investors. This case study was developed for a college first-year seminar focused on the ethics of synthetic biology, and was introduced during the first week of the semester. The case uses the jigsaw teaching method to introduce students both to the mechanics of synthetic biology and to questions about how we should distribute the benefits and burdens associated with new or emerging technologies. It could be adapted for courses in introductory college biology, genetics or bioethics.

This hands-on activity, used in conjunction with the film The Making of the Fittest: Natural Selection in Humans, teaches students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits. It uses simple simulations to illustrate these complex concepts and includes exercises such as calculating allele and genotype frequencies, graphing and interpretation of data, and designing experiments to reinforce key concepts in population genetics.

Made possible through Toyota USA Foundation funding, the REMS curriculum options include nine online lesson plans and interactive activities themed to examine three pressing challenges in the US: preserving sustainable, competitive manufacturing; distributing products and services across the world; and developing and delivering efficient health care services. Each of the lesson plans provides age-appropriate math and science curriculum that tie to the Common Core Learning Standards for elementary, middle and high school students.

This interrupted case study addresses several concepts related to climate change and its effect on the American pika. Often called an indicator species for climate change, the pika has a unique set of variables specific to its environment. Factors such as temperature, snowpack, and vegetation can affect the distribution and ultimately the chances of survival. The case was designed for use in a "flipped" classroom in which students prepare in advance outside of class by filling out a worksheet while watching a video. The video, created by the author of the case, provides students with baseline information that they apply in class to come up with key ideas and predictions, followed by analysis of actual data to test the hypotheses they develop. The case study incorporates group discussion, analysis of experimental design, and data evaluation as central activities and can be taught in a single 50 minute class session. The case was designed for use in a large introductory-level class, but is also appropriate for smaller classes.

This interrupted case study for the flipped classroom applies evolutionary genetics research to human health. Students learn about a naturally occurring, but rare, allele of the CCR5 gene, CCR5-Δ32, which provides resistance to HIV. They use data from primary literature sources to predict and interpret worldwide patterns of CCR5-Δ32 frequency distribution. They then discuss how these allele frequency patterns may have been driven by selection imposed by various diseases or by other evolutionary mechanisms. Next, they test published data using Hardy-Weinberg equilibrium to examine if CCR5-Δ32 also provides genetic resistance to West Nile virus. Finally, they complete a jigsaw discussion of Nature News articles that report on how CCR5 research is being used to develop therapies to treat HIV. Originally written for the evolution portion of a yearlong biology series for undergraduate majors, the case is also appropriate for some non-majors biology courses or, with added complexity, upper-level evolution, genetics, or cell biology courses.

This case study uses an interactive activity to illustrate density dependence in ecology classes. We developed a "hunt" using paper butterflies with warning signals on the upper side of the wings and symbols that indicate if a butterfly is noxious underneath the wings. Butterflies are distributed in four different patches with varying densities of noxious and palatable butterflies, simulating Batesian or Müllerian mimicry. Students can catch as many butterflies they want for a period of time, but if they catch more than three noxious butterflies they are out of the game. After the activity, students calculate the survival rate of each type of butterfly in each patch and discuss the implications of density and warning signals according to their results. Students then answer questions and build graphs using the data from the activity and knowledge from the class and the discussion. With this case study, students will be able to understand negative and positive density dependence, as well as predation, learning, and convergent evolution, while recalling or being introduced to Batesian and Müllerian mimicry.