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This case study was inspired by a real-life scenario, and follows the story of Roberto, a migrant farmworker whose health is impacted by the usage of pesticides on a farm.  With the help of a health care provider, Roberto becomes aware of the effects of pesticides on his well-being. Students utilize a database and draw conclusions from data in order to answer the case questions.  The case concludes with an activity that uses the "intimate debate" technique in which students use scientific data as evidence to argue whether or not the pesticide under discussion should be banned from usage.  This case was originally developed for undergraduate anatomy and physiology or toxicology courses. Students are expected to have some background knowledge in nerve structure and function as well as the mechanics of neural transmission before starting the case.

The external environment's effects upon genes can influence disease, and some of these effects can be inherited in humans. Studies investigating how environmental factors impact the genetics of an individual's offspring are difficult to design. However, in certain parts of the world in which social systems are highly centralized, environmental information that might have influenced families can be obtained. For example, Swedish scientists recently conducted investigations examining whether nutrition affected the death rate associated with cardiovascular disease and diabetes and whether these effects were passed from parents to their children and grandchildren (Kaati et al., 2002). These researchers estimated how much access individuals had to food by examining records of annual harvests and food prices in Sweden across three generations of families, starting as far back as the 1890s. These researchers found that if a father did not have enough food available to him during a critical period in his development just before puberty, his sons were less likely to die from cardiovascular disease. Remarkably, death related to diabetes increased for children if food was plentiful during this critical period for the paternal grandfather, but it decreased when excess food was available to the father. These findings suggest that diet can cause changes to genes that are passed down though generations by the males in a family, and that these alterations can affect susceptibility to certain diseases. But what are these changes, and how are they remembered? The answers to questions such as these lie in the concept of epigenetics.

When Jordan is diagnosed with brain cancer (glioblastoma multiform), his college plans are unexpectedly put on hold. This scenario is presented in order to teach students about gene regulation, as the efficacy of the drug Jordan receives for post-surgical treatment is dependent upon the activity level of a gene encoding a protein involved in DNA repair. This "flipped" case study requires students to prepare in advance outside of class by watching several short videos that have been selected to teach the basics of how cancer forms as well as the role of epigenetics in gene silencing. Inside of class, the case is delivered using progressive disclosure format in which students gradually receive additional information to answer a series of directed questions. To determine a treatment plan for Jordan, students analyze data from a research study involving patients treated for his specific type of cancer. The case is designed for advanced high school biology classes as well as lower-level undergraduate general biology courses for non-majors and majors.

3 min video, Scientists have made a major advancement in the world of cloning-- creating hundreds of identical mice from a single drop of blood. The implications are pretty big. Why? Anthony Carboni as the answers.

Have you ever wondered why people look the way they do? Why our hands and feet have five digits instead of six? Why we stand on two legs instead of four? It took 350 million years of evolution to produce the amazing machine we call the human body and in Your Inner Fish, a three-part series based on the best-selling book of the same name, author and evolutionary biologist Dr. Neil Shubin looks into the past to answer these and other questions.

The following list rebuts some of the most common "scientific" arguments raised against evolution. It also directs readers to further sources for information and explains why creation science has no place in the classroom.

But did they actually live longer? The answer is yes! The average lifespan of monkeys on a regular diet is approximately 26 years, but the CR monkeys lived on average 3 years longer, a whopping 10 percent increase. The statistics suggest at any point in time, the control monkeys had 2.9 times the rate of death from age-related causes compared to those on a CR diet.

9:14 video Have you ever wondered how life first got started on Earth? So do scientists! Though the question has not yet been fully answered, a careful study of Chemical Evolution is beginning to shed light on this mystery. In this film you will learn what Chemical Evolution is, how it works, and how it is different from Biological Evolution.

Our planet's diverse, thriving ecosystems may seem like permanent fixtures, but they're actually vulnerable to collapse. Jungles can become deserts, and reefs can become lifeless rocks. What makes one ecosystem strong and another weak in the face of change? Kim Preshoff details why the answer, to a large extent, is biodiversity.

Why is their so much secrecy in animal research? Can't we do without animals in medical research? In this video Dr Simon Festing, our ex-Chief Executive, answers questions about why animals are an essential part of medical work. Download this film here: http://ww

How do cancer cells grow? How does chemotherapy fight cancer (and cause negative side effects)? The answers lie in cell division. George Zaidan explains how rapid cell division is cancer's "strength" -- and also its weakness.

The elusive octopus genome has finally been untangled, which should allow scientists to discover answers to long-mysterious questions about the animal's alienlike physiology: How does it camouflage itself so expertly? How does it control-and regenerate-those eight flexible arms and thousands of suckers? And, most vexing: How did a relative of the snail get to be so incredibly smart-able to learn quickly, solve puzzles and even use tools?

This case study presents the story of "Nick," a student who has been assigned the task of writing a research paper describing the fundamentals of chemical bonds and how they relate to human life. When Nick experiences difficulty remembering information about the different types of chemical bonds, he turns to his tutor, Josh, for help. Josh explains orbitals and valence electrons to Nick, and then they together review nonpolar and polar covalent bonds, ionic bonds, and hydrogen bonds. A final practical application exercise requires that students write about how different types of chemical bonds may relate to the development of Alzheimer's disease and to the mechanism of action of potential drug treatments.  The case is presented with PowerPoint slides and is designed to be used with a personal response system ("clickers"), but students can instead record their answers on paper or share them verbally.  The content is appropriate for use in high school and undergraduate introductory chemistry and biology courses.

This lesson follows a flipped learning model where teachers don't stand before the class and lecture.  Instead, students become grizzly bear scientists and "discover" the answers to real-world research questions through scientific inquiry. Using real-world demographic data collected over 30 years on grizzly bears in the Greater Yellowstone Ecosystem, students work individually, in three Science Teams, and as a class to determine whether or not this grizzly bear population is biologically ready for delisting.

Answer five simple questions about a bird you are trying to identify and Merlin will come up with a list of possible matches. Merlin offers quick identification help for beginning and intermediate bird watchers to learn about North America's most common birds!

The STAR-G Project has put together fact sheets about disorders commonly screened for by newborn screening. The fact sheets were written specifically for families that have received an initial diagnosis of one of the disorders and want to know more general information. They address issues and answer questions that are of particular concern to parents. Each fact sheet was written by a genetic counselor and reviewed by metabolic and genetic specialists.

Why did you get the flu this winter, but your co-workers didn't? The answer, according to a new study of twins, may have less to do with your genes and more to do with your environment-including your past exposure to pathogens and vaccines. Our immune system is incredibly complex, with diverse armies of white blood cells and signal-sending proteins coursing through our veins, ready to mount an attack on would-be invaders. Everyone's immune system is slightly different-a unique mixture of hundreds of these cells and proteins. But the main driver of this variation is unclear. Although scientists know that our immune system can adapt to our environment-that's why vaccines work, for instance-it is also built by our genes.

Naked mole rats are hairless, blind, underground dwellers that are remarkably impervious to cancer. But why you ask? Well, researchers at the University of Rochester asked that same question and it turns out a cluster of genes, called the INK4 locus, is the answer. This locus, also found in humans and mice, uses that cluster to carry instructions, or encode, for several cancer fighting proteins.

In this video Paul Andersen answers the very simple question: What is cancer? He explains how damage to the DNA can create uncontrolled cell growth. He explains how malignant tumors can spread the disease throughout the body and gives possible treatments.

"Survival of the Fittest: Variations in the Clam Species Clamys sweetus" is a guided inquiry. This series of hands-on activities complements the HHMI DVD Evolution: Constant Change and Common Threads and requires simple materials such as M&Ms, Reese's Pieces, food storage bags, and paper cups. This activity has been designed to engage students in thinking about the mechanism of natural selection by encouraging them to formulate questions that can be answered through scientific investigation, data collection, and pattern recognition.