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This animation describes insulin resistance, an underlying cause of type 2 diabetes. It explains the roles of glucose and the hormone insulin in our body. Symptoms of diabetes are reviewed and various health complications that type 2 diabetes can lead to if left untreated.

This case study explores the topics of diffusion, osmosis, membrane transport, and the physiological significance of glucose and insulin in the human body. The story begins with a high school athlete, Timmy, who is incredibly efficient at metabolizing carbohydrates for energy; this is where the reader is introduced to normal carbohydrate digestion and metabolism for energy within skeletal muscle cells. As Timmy enters college, he withdraws from sports and physical activity but continues to consume massive amounts of highly soluble carbohydrates, resulting in insulin resistance and ultimately type II diabetes. Throughout the case students are prompted with conceptual questions and interactive figures that require the application and transfer of information they have been introduced to. Originally written for intermediate and advanced physiology courses that cover foundational and complex concepts in science, the case is also appropriate for courses in intermediate biology, nutritional sciences, animal sciences, and exercise sciences.

UCSF Diabetes Center researchers explain the basics of both type 1 and type 2 diabetes. Faculty interviewed include Dr. Matthias Hebrok, Dr. Michael German, Dr. Suneil Koliwad, Dr. Stephen Gitelman.

UCSF Diabetes Center researchers explain the basics of both type 1 and type 2 diabetes. Faculty interviewed include Dr. Matthias Hebrok, Dr. Michael German, Dr. Suneil Koliwad, Dr. Stephen Gitelman.

In our view, and that of organizations such as the American Society of Clinical Oncology, the World Cancer Research Fund International, and the American Cancer Society, obesity-related cancers will arguably be the most urgent issue in the cancer field in the next decade.

Some 20 percent of cancer-related deaths in the U.S. can be attributed to obesity, making it the number-one preventable cause of cancer death in the country. But with myriad metabolic and inflammatory changes associated with obesity, determining the mechanisms that underlie the obesity-cancer link has proven challenging.