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In March 2005 High Tech High received a $250,000 grant from the California Department of Education to disseminate project-based learning methods to teachers in non-charter public schools. As part of the project, High Tech High teachers have documented successful projects to share with collaborating teachers from local districts and across the HTH network. The current volume presents the fruits of these labors. The aim is simple: to offer practitioners useful, easily adaptable models of real projects.

On June 14, 2013, the Smithsonian Institution in Washington, D.C. opened the high-tech, high-intensity exhibition Genome: Unlocking Life's Code to celebrate the 10th anniversary of researchers producing the first complete human genome sequence - the genetic blueprint of the human body - in April 2003. The exhibition is a collaboration between the Smithsonian's National Museum of Natural History (NMNH) and the National Human Genome Research Institute (NHGRI) of the National Institutes of Health.

In the wake of a potential global crisis we will investigate the biology of infectious diseases to better understand how they transmit, replicate and induce an immune response in humans. Our objective is to pose solutions to the Ebola outbreak in the United States by studying other infectious diseases. We will investigate infectious diseases and the development of vaccines to show how they have changed the course of human health and populations as a whole. We will determine public perceptions about infectious diseases and identify misconceptions. Ultimately, we will develop community awareness information to manage and in future prevent an outbreak of Ebola.

In The Boneyard Project students learn about anatomy and physiology of small mammals and humans while considering ethical questions about utilizing animal products.

The backbone of New Tech High's unique learning environment is project-based learning (PBL). Instead of handing out daily assignments, teachers assign periodic projects that require critical thinking, creativity, collaboration, and communication.