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The activity begins with students observing different organisms or phenomena and developing questions based on their observations. They then sort their questions into those that can and cannot be answered using the methods of science. Students practice writing scientific questions, designing experiments to address scientific questions, developing questions that involve cause and effect, and understanding the importance of cause and effect questions in scientific research. At the end of the activity, students determine the research questions being asked from reading journal article titles and parts of a published paper or other reported results. Several possible extension activities are provided for continuing the investigation and research of phenomena.

Hyperlinked list of types of questioning with examples.

Many biology courses are designed to develop student understanding and application of the scientific method, but few seriously examine the various ethical questions associated with scientific research. This interdisciplinary case study presents three experiments and asks not only if they are scientifically valid but whether they were ethically performed.  The experiments examine the psychology of love, a cause of breast cancer, and how the immune system functions in the presence of cancer. Based on their opinions of the validity and ethics of each experiment, students are asked to conclude which of the experiments were actually conducted by scientists and which are fictional. Students should already be familiar with the scientific method, but information on the Georgetown Mantra and Nuremberg Code.is included. The case could be modified for use in non-majors and majors classes.  The format of the case challenges students of any background to use information from both science and ethics to see how the differing approaches of scientist and ethicist can complement and strengthen each other.

Naked mole rats are hairless, blind, underground dwellers that are remarkably impervious to cancer. But why you ask? Well, researchers at the University of Rochester asked that same question and it turns out a cluster of genes, called the INK4 locus, is the answer. This locus, also found in humans and mice, uses that cluster to carry instructions, or encode, for several cancer fighting proteins.

This flipped case study begins with a video in which a student reveals a family member's diagnosis with breast cancer and then considers the whirlwind of questions that arise in such a situation. Students are asked to relate to the main character and identify what questions they would have and what resources they could consult to seek information.  This sets the context for students to use websites and videos to investigate the nature of cancer, its causes, and progression. Students then learn about the major methods of cancer treatment (surgery, radiation therapy, and chemotherapy), how they work, and the limitations and side effects of each. The case concludes by addressing the claim of one of the characters that there is a conspiracy to hide a cure for cancer. The case would be implemented near the middle of a high school, non-majors, or introductory biology course after discussion of basic cell biology and the cell cycle.

Our students will face decisions about health, science, and medicine that we can hardly imagine.   How can we keep student needs and science first, yet still create a safe and affirming space for intellectual curiosity? Teaching biology creates many opportunities to authentically incorporate student curiosity. The Next-Generation Science Standards (NGSS) expect students to ask questions about natural phenomena and then explain their answers using models. This website offers examples of adapting curriculum to NGSS and gender-inclusive standards, as well as resources for advocating to administration and others.

This interrupted case study tells the story of Miles, a freshman in college, who volunteers to help with the composting program on campus. Miles is excited about composting but his mother is hesitant to try it at home. Miles learns about the key ingredients for successful composting and his mother eventually begins to see its value. This case is presented in four parts, and can be used with or without the PowerPoint presentation and associated clicker questions (see Supplemental Materials). First, students are asked to analyze waste that they generate at home and identify any material that is compostable. Next, students explore the science of composting. Finally, students explore the topic of human manure to consider composting to the extreme. The case was designed for an environmental science course for non-majors; no prerequisite knowledge is assumed.

This set of mini cases on the ecology of eastern cottontail rabbits is designed to give students practical experience using statistics in a scientific context. Given a dataset and experimental design, groups of students are asked to play the part of a wildlife management researcher to determine the results for each study. Students practice the scientific process and gain experience making hypotheses and predictions, choosing an appropriate statistical test, interpreting and displaying results, and presenting data to others. Students choose between four basic, commonly used, statistical tests (t-test, one-way ANOVA, linear regression, and Chi-square test), and justify their choices. This activity was developed for undergraduate level students and is applicable to biology courses, particularly those dealing with ecology or management. The case is designed for student groups, but could be modified into clicker questions or individual assignments.

Amanda Briody describes two BioInteractive resources focused on Gorongosa National Park in Mozambique. She uses the short film "The Guide: A Biologist in Gorongosa" to introduce students to the park and its scientists. The Gorongosa Interactive Timeline allows her to ask data-based questions on the park's history and ecology, and have students make evidence-based claims.

In the second film of the Great Transitions trilogy, paleontologist Julia Clarke takes us on a journey to uncover the evidence that birds descended from dinosaurs. The discovery of Archaeopteryx in a quarry in Germany in the early 1860s provided the first clue that birds descended from reptiles. But what kind of reptile? In the last 40 years, scientists have identified many shared features between birds and two-legged carnivorous dinosaurs called theropods. The film illustrates many of the practices of science, including asking important questions, formulating and testing hypotheses, analyzing and interpreting evidence, and revising explanations as new evidence becomes available.

I'm sure you've probably heard of at least a few invasive species. Maybe you've heard of the Cane Toad. It's one of the classic introductions of invasive species gone wrong. It was introduced to eat pests in cane fields and then turned into a plague of epic proportions in Northern Australia. But here is the question. Now that these species are here, is it worth fighting their spread, or should we spend time and effort on other things. It's worth asking, and not just for the ethical implications. We live in a modern world and I think there is a real financial element to this as well. See if you can follow my logic through this video short. Do you agree with my thoughts? Should we keep fighting? Do you have any personal experience with an invasive species?

Data Nuggets are free classroom activities, co-designed by scientists and teachers, designed to bring contemporary research and authentic data into the classroom. Data Nuggets include a connection to the scientist behind the data and the true story of their research. Each activity gives students practice working with 'messy data' and interpreting quantitative information. Students are guided through the entire process of science, including identifying hypotheses and predictions, visualizing and interpreting data, making evidence based claims, and asking their own questions for future research. Because of their simplicity and flexibility, Data Nuggets can be used throughout the school year and across grades K-16, as students grow in their quantitative abilities and gain confidence." Sounds like real science to me!

Post the link to the Science News article "Life on Earth may have begun in hostile hot springs" to your virtual classroom. Ask students to read the article for homework and prepare for online class by answering the first question. Before the class meets, provide the students with the links to all articles they will need for class. Class discussion can be conducted via Zoom; the research and recipe-building components can be conducted in breakout rooms.

So you have a research assignment. Do you know where to begin? There is so much information out there on the web that it can be hard to know where to start and what path to take through the 'jungle of information'. The Research Safari is designed to help you do just that. Follow the information / inquiry process described here to help you work through your research task. There are also lots of great resources, tools and information that will help give your assignment that WOW factor. The Research Safari will help you to answer the following questions: What am I actually being asked to do for my assignment? What do I already know about the topic? Where am I going to get the information I need? How do I know that the information is accurate or 'authentic' (not fake)? Which are the best websites to use? ​What is the best way for me to present my assignment? How can I make this the best assignment ever?

Scientists are not sure whether viruses are living or non-living. In general, scientists use a list of criteria to determine if something is alive. Let's look at some traits of living things and see if viruses also have those traits.