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The following programs have due dates that fall between October 1 - 25, 2013, and these dates are being revised due to the Federal  government shutdown. These revised dates apply whether the proposal is being submitted via the NSF FastLane System or  Grants.gov. Due to compressed proposal deadlines resulting from the shutdown, proposers are advised that they may experience a  delay when contacting IT Help Central with technical support questions. Frequently asked questions regarding these date changes  are available on the Resumption of Operations page on the NSF website at: http://www.nsf.gov/bfa/dias/policy/postshutdown.jsp. 

The National Science Foundation (NSF) announces a third year of a program on collaborative research and education in the area of scalable nanomanufacturing, including the long-term societal implications of the large-scale implementation of nanomanufacturing innovations. This program is in response to and is a component of the National Nanotechnology Initiative Signature Initiative: Sustainable Nanomanufacturing - Creating the Industries of the Future (http://www.nano.gov/node/611). Although many nanofabrication techniques have demonstrated the ability to fabricate small quantities of nanomaterials and devices for characterization and evaluation purposes, the emphasis of this program is on research to overcome the key impediments that prevent the low cost production of useful nanomaterials, devices and systems at industrially relevant scale. Therefore, competitive proposals will incorporate three elements in their research plans:A persuasive argument that the nanomaterials, devices or systems to be produced have or are likely to have sufficient demand to justify eventual scale-up;A clearly identified and arguably complete set of research issues that must be addressed to enable the low cost production of high quality products; andA compelling research plan with clear objectives to overcome the identified research issues that is supported by preliminary results relevant to scale-up.

The National Science Foundation (NSF) announces a fifth year of a program on collaborative research and education in the area of Scalable Nanomanufacturing. This program is in response to and is a component of the National Nanotechnology Initiative Signature Initiative: Sustainable Nanomanufacturing - Creating the Industries of the Future (http://www.nano.gov/node/611). Although many nanofabrication techniques have demonstrated the ability to fabricate small quantities of nanomaterials, nanostructures and nanodevices for characterization and evaluation purposes, the emphasis of the Scalable Nanomanufacturing program is on research to overcome the key scientific and technical barriers that prevent the production of useful nanomaterials, nanostructures, devices and systems at an industrially relevant scale, reliably, and at low cost and within environmental, health and safety guidelines. Competitive proposals will incorporate three elements in their research plans:

This Funding Opportunity Announcement (FOA) invites applications for the development of innovative research projects in cancer nanotechnology. This initiative, to be known as Innovative Research in Cancer Nanotechnology (IRCN), is an integral component of a broader program - the NCI Alliance for Nanotechnology in Cancer (The Alliance) (http://nano.cancer.gov). IRCN awards are designed to enable multi-disciplinary research and transformative discoveries in cancer biology and/or oncology through the use of nanotechnology. Proposed projects should address major barriers in cancer biology and/or oncology using nanotechnology and should emphasize fundamental understanding of nanomaterial interactions with biological systems and/or mechanisms of their in vivo delivery.

The National Science Foundation (NSF) announces a fourth year of a program on collaborative research and education in the area of scalable nanomanufacturing, including the long-term societal implications of the large-scale implementation of nanomanufacturing innovations. This program is in response to and is a component of the National Nanotechnology Initiative Signature Initiative: Sustainable Nanomanufacturing - Creating the Industries of the Future (http://www.nano.gov/node/611.) Although many nanofabrication techniques have demonstrated the ability to fabricate small quantities of nanomaterials, nanostructures and nanodevices for characterization and evaluation purposes, the emphasis of the scalable nanomanufacturing program is on research to overcome the key scientific and technological barriers that prevent the production of useful nanomaterials, nanostructures, devices and systems at an industrially relevant scale, reliably, and at low cost and within environmental, health and safety guidelines. 

The purpose of this FOA is to support projects to develop tools and strategies for studying: 1. the three dimensional architecture of the nucleus in relationship to the topography of nuclear bodies and transcriptional machineries, 2. the structure and function of poorly characterized nuclear structures, or 3. the role of specialized proteins and RNAs in the assembly, organization, and function of nuclear bodies, nuclear structures, and specialized subnuclear domains. - See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-14-008.html#sthash.HQemmZlU.dpuf

The purpose of this FOA is to seek, identify and support bold and innovative approaches to broaden graduate and postdoctoral training, such that training programs reflect the range of career options that trainees (regardless of funding source) ultimately may pursue and that are required for a robust biomedical, behavioral, social and clinical research enterprise. Collaborations with non-academic partners are encouraged to ensure that experts from a broad spectrum of research and research-related careers contribute to coursework, rotations, internships or other forms of exposure. This program will establish a new paradigm for graduate and postdoctoral training; awardee institutions will work together to define needs and share best practices.

The Research Experiences for Undergraduates (REU) program supports active research participation by undergraduate students in any of the areas of research funded by the National Science Foundation. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. This solicitation features two mechanisms for support of student research: (1) REU Sites are based on independent proposals to initiate and conduct projects that engage a number of students in research. REU Sites may be based in a single discipline or academic department or may offer interdisciplinary or multi-department research opportunities with a coherent intellectual theme. Proposals with an international dimension are welcome. (2) REU Supplements may be included as a component of proposals for new or renewal NSF grants or cooperative agreements or may be requested for ongoing NSF-funded research projects.

Despite the increasing number of complex parenteral dosage forms including polymeric micelles, liposomes, nanosuspensions and others, currently there is still a lack of compendial or biorelevant in vitro drug release assays for these complex dosage forms. The purpose of this study is to evaluate current in vitro release methods for complex parenteral dosage forms and analyze their capability of detecting formulation differences, predicting in-vivo performance, as well as their method robustness. This study is intended to advance the regulatory review process of complex parenteral drug products, which in turn will help provide the US public with access to high quality generic complex parenteral drug products.

The Small Business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The SBIR program solicits proposals from the small business sector consistent with NSF's mission. The program is governed by Public Law 112-81 (SBIR/STTR Reauthorization Act of 2011). A main purpose of the legislation is to stimulate technological innovation and increase private sector commercialization. The NSF SBIR program is therefore in a unique position to meet both the goals of NSF and the purpose of the SBIR legislation by transforming scientific discovery into both social and economic benefit, and by emphasizing private sector commercialization. Accordingly, NSF has formulated broad solicitation topics for SBIR that conform to the high-technology investment sector's interests. The topics are: Biological and Chemical Technologies (BC) Education Applications (EA) Electronics, Information and Communication Technologies (EI) Nanotechnology, Advanced Materials, and Manufacturing (NM)

The MPM program supports fundamental, hypothesis-driven research on the interrelationship of materials processing, structure, properties, performance and process control. Analytical, experimental, and numerical studies are supported, including novel processing methods for any materials system (metals, polymers, ceramics, hybrids, composites, etc.). Proposed research should include the consideration of cost, performance, and feasibility of scale-up, as appropriate. Research that address multi-scale and/or multi-functional materials systems is encouraged as is research in support of environmentally-benign manufacturing. Collaborative proposals with industry (GOALI) are encouraged. Research on micro-scale (and larger) processes is funded by the MPM program; research on processing at the submicron or nano scale is funded by the Nanomanufacturing (NM) program. Research on solid freeform fabrication processes is funded by the Manufacturing Machines and Equipment (MME) program, as are material removal process proposals such as cutting or grinding. Proposals that focus on research leading to new paradigms of material systems design should consider the Design of Engineering Material Systems (DEMS) program. Proposals that primarily focus on fundamental material composition-structure-property studies, where neither processing nor manufacturing plays a significant role in the proposed work, should be submitted to the Materials and Surface Engineering (MSE) program or to the appropriate program in the DMR division.Investigators wishing to serve on a proposal review panel should email the Program Director with a short biographical sketch, a list of areas of expertise and/or a link to their home page. REU/RET supplement requests should be submitted by March 31 each year.

The Environmental Health and Safety of Nanotechnology (Nano EHS) program provides support to examine and mitigate the environmental effects of nanotechnologies. Fundamental research is sought to understand, evaluate, and lessen the impact of nanotechnology on the environment and biological systems. The program emphasizes engineering principles underlying the environmental health and safety impacts of nanotechnology. Innovative methods related to clean nanomaterials production processes, waste reduction, recycling, and industrial ecology of nanotechnology are also of interest.

The Thermal Transport Processes program supports engineering research aimed at gaining a basic understanding of the thermal transport phenomena at nano/micro and macro scales in (1) cooling and heating of equipment and devices, (2) energy conversion, power generation and thermal energy storage and conservation, (3) the synthesis and processing of materials including advanced manufacturing, (4) the propulsion of air and land-based vehicles, and (5) thermal phenomena in biological systems.

The Fluid Dynamics program supports fundamental research and education on mechanisms and phenomena governing fluid flow. Proposed research should contribute to basic understanding; thus enabling the better design; predictability; efficiency; and control of systems that involve fluids. Encouraged are proposals that address innovative uses of fluids in materials development; manufacturing; biotechnology; nanotechnology; clinical diagnostics and drug delivery; sensor development and integration; energy and the environment. While the research should focus on fundamentals, a clear connection to potential application should be outlined.

To continue to strengthen the innovation ecosystem, NSF is revising NSF 12-511 to promote two choices under the Partnerships for Innovation (PFI): Accelerating Innovation Research (AIR) subprogram.  The first choice, Technology Translation, encourages the translation of technologically-promising research discoveries made by prior and/or current NSF-funded investigators toward a path of commercialization; while the second choice, Research Alliance, promotes synergistic collaborations between an existing NSF-funded research alliance (including consortia such as Engineering Research Centers, Industry University Cooperative Research Centers, Science and Technology Centers, Nanoscale Science and Engineering Centers, Materials Research Science and Engineering Centers, Centers for Chemical Innovation, and Emerging Frontiers in Research and Innovation grantees) and other public and private entities to motivate the translation and transfer of research discoveries into innovative technologies and commercial reality.  Both of these choices are designed to accelerate innovation that results in the creation of new wealth and the building of strong local, regional, and national economies.

This solicitation aims at introducing nanoscale science, engineering, and technology through a variety of interdisciplinary approaches into undergraduate engineering education. The focus of the FY 2013 competition is on nanoscale engineering education with relevance to devices and systems and/or on the societal, ethical, economic and/or environmental issues relevant to nanotechnology.

The Particulate and Multiphase Processes program supports fundamental and applied research on phenomena governing particulate and multiphase processes, including flows of suspensions of particles, drops or bubbles, granular and granular-fluid flows, flow behavior of micro or nano-structured fluids, aerosol science and technology, and self- and directed-assembly processes involving particulates. Innovative research is sought that contributes to improving the basic understanding, design, predictability, efficiency, and control of particulate and multiphase processes with particular emphasis on: novel manufacturing techniques, multiphase systems of relevance to energy harvesting, multiphase transport in biological systems or biotechnology, and environmental sustainability.

The Research Experiences for Undergraduates (REU) program supports active research participation by undergraduate students in any of the areas of research funded by the National Science Foundation. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. This solicitation features two mechanisms for support of student research: (1) REU Sites are based on independent proposals to initiate and conduct projects that engage a number of students in research. REU Sites may be based in a single discipline or academic department or may offer interdisciplinary or multi-department research opportunities with a coherent intellectual theme. Proposals with an international dimension are welcome. (2) REU Supplements may be included as a component of proposals for new or renewal NSF grants or cooperative agreements or may be requested for ongoing NSF-funded research projects.

The INSPIRE awards program was established to address some of the most complicated and pressing scientific problems that lie at the intersection of traditional disciplines.  It is intended to encourage investigators to submit bold, exceptional proposals that some may consider to be at a disadvantage in a standard NSF review process; it is not intended for proposals that are more appropriate for existing award mechanisms.