This Funding Opportunity Announcement (FOA) invites a High Impact Research and Research Infrastructure Cooperative Agreement application (UC4) from the Program Director/Principal Investigator (PD/PI) of the Data Coordinating Center (DCC) that has been involved in study design and coordination, and data and biosample acquisition and management, since the inception of The Environmental Determinants of Diabetes in the Young (TEDDY) consortium, an ongoing epidemiological study.