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This funding opportunity announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose development of a broad base of innovative technologies in biomedical computing, informatics, and Big Data Science that will support rapid progress in areas of scientific opportunity in biomedical research. It is expected that this research and development is conducted in the context of important biomedical and behavioral research problems. As such, applications are intended to develop enabling technologies that could apply to the interests of most NIH Institutes and Centers and range from basic biomedicine to research in all relevant organ systems and diseases. Major themes of research include collaborative environments; data integration; analysis and modeling methodologies; and novel computer science and statistical approaches. New opportunities are also emerging as large and complex data sets are becoming increasingly available to the research community.

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that develop new knowledge in two core programs: Computer Systems Research (CSR) program; and Networking Technology and Systems (NeTS) program. Proposers are invited to submit proposals in three project classes, which are defined as follows: Small Projects - up to $500,000 total budget with durations up to three years; Medium Projects - $500,001 to $1,200,000 total budget with durations up to four years; and Large Projects - $1,200,001 to $3,000,000 total budget with durations up to five years.

This funding opportunity enables engineering and computer science departments to lead the nation by successfully achieving significant sustainable changes necessary to overcome longstanding issues in their undergraduate programs and educate inclusive communities of engineering and computer science students prepared to solve 21^st-century challenges.

The advancement of sensing technology such as RGBD (Red Green Blue Depth), multi-camera and light field imaging systems, networks of sensors, advanced visual analytics and cloud computing will challenge the longstanding paradigms of capturing, creating, analyzing and utilizing visual information. Advances in Visual and Experiential Computing (VEC) will enable capability, adaptability, scalability, and usability that will far exceed the simple information systems of today. VEC technology will transform the way people interact with visual information through, for example, the realization of new mobile and wearable devices and the emergence of autonomous machines and semantically aware spaces. VEC research will drive innovation and competition in many industrial sectors as well as enhance the quality of life for ordinary people. Fast growing visual data has become a bottleneck in human decision processes in several emergent situations. New VEC technology is crucial to extracting information from complex visual and related data sets, combining this information with intuitive modes of human perception, and generating actionable information. The goal of this joint solicitation between NSF and Intel is to foster novel, transformative, multidisciplinary approaches that promote research in VEC technologies, taking into consideration the various challenges present in this field. This solicitation aims to foster a research community committed to advancing research and education at the confluence of VEC technologies, and to transitioning its findings into practice. NSF and Intel will support three types of projects, each three years in duration: Small projects with funding from $500,000 to $1,000,000 per project; Medium projects with funding from $1,000,001 to $2,000,000 per project; and Large projects with funding from $2,000,001 to $3,000,000.?? It is intended that NSF and Intel will cofund each project in equal amounts. This NSF/Intel partnership combines CISE??s experience

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that take a system-oriented approach to the development of novel computing and networking technologies, or to the enhancement of existing systems in any of several dimensions, or that explore new ways to make use of existing technologies.

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that take a system-oriented approach to the development of novel computing and networking technologies, or to the enhancement of existing systems in any of several dimensions, or that explore new ways to make use of existing technologies. Proposers are invited to submit proposals in three project classes, which are defined as follows:

The HVSI funds and performs a range of hypersonic research tasks in support of the Department of Defense (DoD) High Performance Computing Modernization Program (HPCMP). HPCMP desires to improve computational simulations of hypersonic vehicles in support of DoD goals by accelerating the successful development of HPC software and hardware. The HVSI will be looking to improve computational simulation approaches including numerical methods, modeling approaches, and simulation of a variety of aerothermodynamic and propulsion aspects of hypersonic flight. Specific science and technology areas include turbulence, boundary layer transition, fluid-structure-thermal interactions, non-equilibrium chemistry, ablation, and combustion.

BJA’s Student Computer Forensics and Digital Evidence Educational Opportunities Program is an innovative new program that seeks to partner with an institution of higher education to further educational opportunities for students in the fields of computer forensics and digital evidence. This practical and academic program will better prepare students for employment within federal, state, local, territorial, and tribal law enforcement agencies that are charged with the prevention, investigation, and response to economic, cyber, and high-tech crimes.

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that develop new knowledge in two core programs: Computer Systems Research (CSR) program; and Networking Technology and Systems (NeTS) program.

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that develop new knowledge in two core programs: Computer Systems Research (CSR) program; and Networking Technology and Systems (NeTS) program. Proposers are invited to submit proposals in three project classes, which are defined as follows: Small Projects - up to $500,000 total budget with durations up to three years; Medium Projects - $500,001 to $1,200,000 total budget with durations up to four years; and Large Projects - $1,200,001 to $3,000,000 total budget with durations up to five years.

New information technologies can be envisioned that are based on biological principles and that use biomaterials in the fabrication of devices and components; it is anticipated that these information technologies could enable stored data to be retained for more than 100 years and storage capacity to be 1,000 times greater than current capabilities. These could also facilitate compact computers that will operate with substantially lower power than today's computers. Research in support of these goals can have a significant impact on advanced information processing and storage technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, engineering, physics, chemistry, materials science, computer science, and information science that will enable heretofore-unanticipated breakthroughs as well as meet educational goals.

The Division of Earth Sciences (EAR) will consider proposals for the development of cyberinfrastructure for the geosciences (Geoinformatics).  EAR seeks the development and implementation of enabling information technology with impacts that extend beyond an individual investigator or small group of investigators and that facilitates the next generation of geosciences research.  Proposals to this solicitation may seek support for community-driven development and implementation of databases; tools for data integration, interoperability, and visualization; software development and code hardening; and data-intensive/new computing methodologies that support the enhancement of geosciences research and education activities. Collaboration with computational scientists and the development of public/private partnerships are strongly encouraged.

Software is an integral enabler of computation, experiment and theory and a primary modality for realizing the Cyberinfrastructure Framework for 21st Century Science and Engineering (CIF21) vision, as described in http://www.nsf.gov/pubs/2010/nsf10015/nsf10015.jsp. Scientific discovery and innovation are advancing along fundamentally new pathways opened by development of increasingly sophisticated software. Software is also directly responsible for increased scientific productivity and significant enhancement of researchers' capabilities. In order to nurture, accelerate and sustain this critical mode of scientific progress, NSF has established the Software Infrastructure for Sustained Innovation (SI2) program, with the overarching goal of transforming innovations in research and education into sustained software resources that are an integral part of the cyberinfrastructure. SI2 is a long-term investment focused on catalyzing new thinking, paradigms, and practices in developing and using software to understand natural, human, and engineered systems. SI2's intent is to foster a pervasive cyberinfrastructure to help researchers address problems of unprecedented scale, complexity, resolution, and accuracy by integrating computation, data, networking, observations and experiments in novel ways.

The "Campus Cyberinfrastructure - Network Infrastructure and Engineering (CC-NIE)" program invests in improvements and re-engineering at the campus level to support a range of data transfers supporting computational science and computer networks and systems research. The program also supports Network Integration activities tied to achieving higher levels of performance, reliability and predictability for science applications and distributed research projects. Two types of CC-NIE awards will be made. Data Driven Networking and Infrastructure for the Campus and Researcher awards will be supported at up to $500,000 total for up to 2 years. Network Integration and Applied Innovation awards will be supported at up to $1,000,000 total for up to 2 years.

Eligible applicants are postdoctoral fellows and faculty at degree-granting institutes in the United States or Canada. Applicants must hold a Ph.D. in mathematics, physics, chemistry, computer science, statistics, or engineering and be interested in investigating research opportunities in the biological sciences. Biologists holding a doctorate degree at the time of application who are interested in working with physical scientists, mathematicians, engineers, chemists, statisticians, or computer scientists to incorporate their ideas and approaches to answering biological questions are eligible to apply.

VirtUE seeks to leverage the federal government's impending migration to commercial cloud based information Technology (IT) infrastructures and the current explosion of new virtualization and operating system (OS) concepts to create and demonstrate a more secure interactive user computing environment (UCE) than the government has had in the past or likely to have in the near future. Currently the government UCE is represented by a general purpose Windows desktop OS running multiple installed applications hosted on either a dedicated physical computer or on a shared virtualized platform. When a desktop OS is hosted on a shared virtualized platform, it is called a virtualized desktop interface or VDI.

Quantum Information Science (QIS) supports theoretical and experimental proposals that explore quantum applications to new computing paradigms or that foster interactions between physicists, mathematicians, and computer scientists that push the frontiers of quantum-based information, transmission, and manipulation.

The Challenge seeks designs that lead to the acquisition of academic, technical, and employability skills through engaging simulated experiences in the hybrid reality continuum. For the purpose of this notice, ``hybrid reality continuum'' refers to the range of computer-generated simulations that extend from completely simulated environments to environments that incorporate aspects of the real world. For the purpose of this Challenge, ``EdSim'' is broadly defined as computer-generated three-dimensional learning environments, including virtual, augmented, and mixed realities that draw upon or mimic real-world experiences and are designed to educate users.

This BAA focuses on developing new technologies to allow secure data sharing; trusted computing; smart routing; cyber defense; Multi-Level Security (MLS) trust at the tactical edge; and a comprehensive, multi-security domain, user-defined operational picture to effectively and efficiently improve the state-of-the-art for defense enterprise, cloud, and mobile/tactical computing/operations.

The BIGDATA program seeks novel approaches in computer science, statistics, computational science, and mathematics, along with innovative applications in domain science, including social and behavioral sciences, geosciences, education, biology, the physical sciences, and engineering that lead towards the further development of the interdisciplinary field of data science