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This National Aeronautics and Space Administration (NASA) Research Announcement (NRA) solicits ground-based research proposals from established researchers and graduate students to generate new scientific insights by utilizing experimental data residing in NASA's Physical Sciences Informatics (PSI) system (http://psi.nasa.gov), an online database of completed physical science reduced-gravity flight experiments conducted on the International Space Station (ISS), Space Shuttle flights, and Free-flyers, or from related ground-based studies. The solicitation (NNH17ZTT001N-17PSI-D), entitled "Use of the NASA Physical Sciences Informatics System - Appendix D," will be available on or about September 15, 2017. Upon release, the solicitation will be found via the following steps: 1. Open the NSPIRES homepage at http://nspires.nasaprs.com/ 2. Select "Solicitations" 3. Select "Open Solicitations" 4. Select "Use of the NASA Physical Sciences Informatics System NNH17ZTT001N" 5. Select List of Open Program Elements 6. Select "Use of the NASA Physical Sciences Informatics System - Appendix D" 7. Select "Appendix D NNH17ZTT001N-17PSI-D" under Announcement Documents. NASA plans to host a proposers' conference via WebEx shortly after the release of the Appendix to provide more information and to answer questions about the NRA and the PSI system. NASA's Physical Sciences Research Program conducts fundamental and applied physical sciences research, with the objective of enabling exploration and pioneering scientific discovery.

The Office of National Drug Control Policy (ONDCP), Executive Office of the President, is seeking applications from public nonprofit institutions/organizations (includes institutions of higher education and hospitals) to perform research and analysis of data to inform drug policy. This project seeks to further refine a methodology for obtaining drug early warning indicators from expanded testing of urine samples that were previously collected and tested as part of an existing drug test protocol. This method was initially developed using local criminal justice populations - including persons in pre-trial or lock-up, parolees or probationers, and drug court participants. In addition, this method was also tested in two trauma units, with promising results. This project will use similar methodology in criminal justice, health care, and other venues, to include opioid treatment admissions, trauma units or emergency departments, and criminal justice programs such as parole or probation, where biological samples are often collected from clients.

The purpose of this Funding Opportunity Announcement (FOA) is to seek applications for the George M. O'Brien Urology Cooperative Research Centers Program. This program will provide a coordinated platform for multidisciplinary interactions between basic and clinical scientists with the overall goal of understanding the etiology and development of benign urologic diseases and disorders, and providing a collaborative venue to design better treatments, diagnostics, and prevention strategies for these disease conditions within the NIDDK mission interests. This program will also serve as a national resource to the larger urological research community and provide educational enrichment opportunities to scientists electing to pursue research in benign urology. Accordingly, applications are sought from individuals willing to cooperate with the NIDDK under a cooperative centers program. The funded Centers will work with the NIDDK in facilitating research collaborations and interactions within and among centers and with the larger research community to accomplish the overall goal of improving treatment of urologic disorders through enhanced communication and research excellence.

The purpose of this funding opportunity announcement is to encourage applications on biomarker discovery that utilize metabolomics approaches to advance the understanding, assessment and management of symptoms.

The purpose of this document is to advise the public that NOAA/NOS/National Centers for Coastal Ocean Science (NCCOS and the NOAA Ocean Acidification Program (OAP) are soliciting proposals for the Identification and Application of Acidification Thresholds in Coastal Ecosystems. Funding is contingent upon the availability of Fiscal Year 2018 Federal appropriations. It is anticipated that projects funded under this announcement will have a September 1, 2018 start date. Total funding for this research: Applicants should submit proposals not to exceed $350,000 per year for projects generally 2-3 years in duration, with a total multi-year budget not to exceed $1,050,000. If funds become available for this program, up to approximately $1,000,000 may be available in Fiscal Year 2018 for the first year of about 1-3 projects with expected start dates of September 1, 2018. Funding for this program is contingent upon availability of funds, which may not have been appropriated at the time of this announcement.. While projects are expected to be 2-3 years in scope, funding may be spread over 4 federal fiscal years depending on how project timelines align with federal budgets.

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate developmental research evaluating the effect of care planning on self-management of late effects of cancer therapy; adherence to medications, cancer screening, and health behavior guidelines; utilization of follow-up care; survivors' health and psychosocial outcomes. How organizational-level factors influence the implementation of care planning and its associated costs is also of interest. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care; 3) evaluate effects of planning on systems outcomes, such as associated costs and impact on providers and organizations implementing the care planning; and 4) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions that improve follow-up care for cancer survivors.

The Office of Cooperative Threat Reduction (CTR), part of the Department's Bureau of International Security and Nonproliferation (ISN), sponsors foreign assistance activities funded by the Nonproliferation, Anti-terrorism, Demining and Related Programs (NADR) account, and focuses on mitigating proliferation risk in frontline states and regions where terrorist threats are on the rise, such as in the Middle East, Africa and Asia. ISN/CTR administers the Chemical Security Program (CSP) in partnership with government, security, academic, and industrial communities to strengthen their ability to prevent chemical attacks. CSP secures chemical weapons-related assets (such as chemicals, equipment, technologies, expertise, and infrastructure) against terrorist networks and proliferant states intent on conducting chemical attacks. To accomplish this mission, CSP sponsors efforts to identify and address chemical security vulnerabilities and to detect and investigate early warning signs of chemical attacks. CSP focuses its resources in countries where non-state actors and returning foreign fighters have demonstrated an ability or interest in using chemical weapons, and seeks to instill sustainable chemical security capabilities in partner countries.

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research evaluating the effect of care planning on self-management of late effects of cancer therapy; adherence to medications, cancer screening, and health behavior guidelines; utilization of follow-up care; survivors' health and psychosocial outcomes. How organizational-level factors influence the implementation of care planning and its associated costs is also of interest. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care; 3) evaluate effects of planning on systems outcomes, such as associated costs and impact on providers and organizations implementing the care planning; and 4) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions that improve follow-up care for cancer survivors.

The purpose of this funding opportunity announcement is to encourage applications on biomarker discovery that utilize metabolomics approaches to advance the understanding, assessment and management of symptoms.

1. Lithium-ion Battery Safety. Safety concerns continue to hamper full adoption of lithium-ion batteries for defense systems, despite significant research investments by the government and the private sector. This Defense initiative will advance promising lithium-ion battery safety technologies at university research laboratories into early laboratory prototypes and potentially minimum viable products for adoption by the defense and commercial sectors via early startups, small businesses and non-traditional defense contractors. Specific technical areas of interest include, but are not limited to, the following: improved electrolytes; stable high-energy anodes and cathodes; cell components and structures that enhance safety and reliability (e.g. use of electrode coatings and electrolyte additives); safety optimization through battery and battery module design and packaging; and battery management and state of health techniques that prevent and/or mitigate catastrophic failure. 2. Electrical Grid Reliability, Resiliency and Security. Both the defense and commercial sectors recognize the ever-growing criticality to enhance electrical grid reliability, resiliency and security through innovation at the component and system levels. This Defense initiative will advance relevant electrical grid innovations at university research laboratories into early laboratory prototypes and potentially minimum viable products for adoption by the defense and commercial sectors via early startups, small businesses and non-traditional defense contractors. Specific technical areas of interest include, but are not limited to, the following: advanced electrical power generation, transmission and distribution hardware and software; physical cyber secured industrial controls hardware and software; effective control of microgrids supporting high-dynamic loads; electrical grid protocols and controls to maintain secured operations of critical infrastructure under adverse conditions; hardening of e

The objectives of the Funding Opportunity Announcement (FOA) are to continue the development of carbon capture technologies to either the engineering scale or to a commercial design.

The Thermal Transport Processes program is part of the Transport Phenomena cluster, which includes also 1) Combustion and Fire Systems; 2) Fluid Dynamics; and 3) Particulate and Multiphase Processes. The Thermal Transport Processes (TTP) program supports engineering research projects that lay the foundation for new discoveries in thermal transport phenomena. These projects should either develop new fundamental knowledge or combine existing knowledge in thermodynamics, fluid mechanics, and heat and mass transfer to probe new areas of innovation. The program seeks transformative projects with the potential for improving our basic understanding, predictability and application of thermal transport processes. Projects should articulate the contribution(s) to the fundamental knowledge supporting thermal transport processes and state clearly the potential application(s) impact when appropriate. Projects that combine analytical, experimental and numerical efforts, geared toward understanding, modeling and predicting thermal phenomena, are of great interest. Collaborative and interdisciplinary proposals for which the main contribution is in thermal transport processes fundamentals are also encouraged.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage cooperative agreement (U54) applications from multidisciplinary groups of investigators to accelerate the rate of progress in determining the functional, pharmacological, neuronal network and whole animal consequences of genetic variants discovered in patients with various types of epilepsy and to develop strategies for establishing diagnostic criteria and identifying potential targets for intervention.

Currently, the drugs are designed in such a way that the active pharmaceutical ingredient (API) is immediately released in the stomach and absorbed in the bloodstream, rapidly relieving the patient from his/her pain (left-hand side). In case multiple doses are taken all at once, a (potentially toxic) supratherapeutic amount of API immediately gets into the user's bloodstream (center). This amount is illicitly used to induce euphoria and could be potentially toxic. Grünenthal's intention is to design a drug formulation that guarantees the API's release profile in case of proper therapeutical usage. However, in case multiple drug units are taken, the release of API, that is available for absorption (right-hand side), will be limited or, at least, decreased to avoid overdosing.

With this DCL, ECR invites proposals on the development, application, and extension of formal models and methodologies for STEM education research and evaluation, including methods for improving statistical modeling, qualitative modeling, measurement, replication, and learning analytics. This includes research on methodological aspects of new or existing procedures for data collection, curation, and inference in STEM education. Similarly, ECR seeks proposals related to collection of unique databases with cross-boundary value, particularly when paired with innovative developments in measurement or methodology (standard statistical modeling, qualitative research, measurement, replication and learning analytics). Proposers must demonstrate how advances in the methodology will support important theoretical insights in STEM education research or evaluation. Proposers are encouraged to explore a wide range of fundamental research projects (in the areas of quantitative, qualitative, measurement, replication, and learning analytics methodologies)

The goal of the Great Lakes Restoration Initiative (GLRI) is to target the most significant environmental problems in the Great Lakes ecosystem by funding and implementing projects that address these problems. This single source funding opportunity to The Nature Conservancy funds fee title acquisition of land from a willing seller at the Bailey's Harbor Boreal Forest and Wetlands State Natural Area in Door County, Wisconsin. The program authorizing statutes for GLRI awards are listed in CFDA number 15.662 located at CFDA.gov.

The purpose of this research is to identify, implement, and evaluate the use of effective strategies and tools for provider and patient use to taper and/or discontinue opioids, benzodiazepines, and other medications in which risk outweighs benefits to prevent falls, overdose, and other injuries among community dwelling older adults.

The purpose of the Cyberlearning for Work at the Human-Technology Frontier program is to fund exploratory and synergistic research in learning technologies to prepare learners to excel in work at the human-technology frontier. This program responds to the pressing societal need to educate and re-educate learners of all ages (students, teachers and workers) in science, technology, engineering, and mathematics (STEM) content areas to ultimately function in highly technological environments, including in collaboration with intelligent systems. Innovative technologies can reshape learning processes, which in turn can influence new technology design. Learning technology research in this program should be informed by the convergence of multiple disciplines: education and learning sciences, computer and information science and engineering, and cognitive, behavioral and social sciences. This program funds learning technology research in STEM and other foundational areas that enable STEM learning.

The Fusion Energy Sciences (FES) of the Office of Science (SC), U.S. Department of Energy (DOE), herby announces its interest in receiving applications to carry out experimental research in magnetic fusion energy sciences on long-pulse overseas stellarator facilities, namely Wendelstein 7-X (Germany) and the Large Helical Device (LHD - Japan). The research should be related to the planning, execution, and analysis of experiments concerning the topical areas described below. The FES Burning Plasma Science: Long Pulse portfolio supports U.S. researchers who work in collaboration with foreign scientists to explore critical science and technology issues at the frontiers of magnetic fusion research. These collaborations take advantage of the unique capabilities of the most advanced overseas research facilities.

This NOFO will support achievement of national targets for 2018 antiretroviral therapy (ART) scale-up towards the UNAIDS Fast Track Targets in Ukraine. The recipient will implement innovative and effective recruitment and case management models for persons who inject drugs (PWID) and men who have sex with men (MSM) at the community level. These innovative changes will increase uptake of HIV community based testing and increase ART initiation for these populations. The recipient will pilot risk network-based testing using point-of-care recency assays to link recently infected PWID to care. The project will focus on the six regions with the highest HIV burden (Dnipropetrovsk, Mykolayiv, Odesa, government controlled areas (GCA) of Donetsk, Kyiv City, and Kherson) and continue to work in six additional medium burden oblasts (Cherkasy, Poltava, Chernihiv, Zaporizhzhya, Kirovohrad, and Kyiv). The recipient will also increase the capacity of the Government of Ukraine’s Center for Public Health (CPH) and regional monitoring and evaluation (M&E) centers specialists to conduct data analysis using statistical software and build institutional capacity to conduct economic evaluations of HIV interventions. Illustrative strategic information (SI) activities include development of trainings to support the Ministry of Health (MOH) and the newly established CPH in using statistical software, routine analysis of surveillance data, study design, and research protocol development.