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MiamiOH OARS

2018 Part the Cloud: Translational Research Funding for Alzheimer's Disease - 0 views

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    Applications will be accepted from academic investigators and small companies with lead candidate therapeutic agents that require early stage testing prior to Proof of Concept (POC) Phase 2 or 3 efficacy studies, or with lead therapeutic agents that have already established human safety data and require a small-scale pilot Proof of Mechanism (POM) study in humans to begin proving the scientific concept in humans. This award will support Phase 1 studies or pilot small- scale Phase 2a studies for repurposed drugs in normal individuals or individuals with preclinical or symptomatic Alzheimer's disease (i.e. early human studies to set the stage for efficacy studies), including single and multiple dose studies to establish safety, brain penetration and/or target engagement and POM in preparation for larger proof of concept trials. In addition, proposals may be considered that are POC to validate biological marker(s) of disease progression in a clinical trial environment. Any proposal must have a clear focus on Alzheimer's disease and related disorder and be translational in nature. All proposals should clearly and explicitly outline the measure to be investigated, the methods for study, and outcomes. Researchers from underrepresented groups are encouraged to apply.
MiamiOH OARS

American Heart Association / Allen Initiative in Brain Health and Cognitive Impa - 0 views

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    As health advances allow people to live longer, healthy aging has become an urgent frontier for research. The burden of age-related cognitive impairment - whether from Alzheimer's disease, vascular dysfunction, or other causes - is growing exponentially. To accelerate collaborative brain-aging research, the Paul G. Allen Frontiers Group and the American Heart Association/American Stroke Association are committing $43 million with additional partners to co-fund a new research initiative with the goal of shedding new light on how to better prevent, detect, and treat age-related cognitive impairment, including Alzheimer's disease.
MiamiOH OARS

AHA, Allen Frontiers Group Issue RFP for Initiative in Brain Health and Cognitive Impai... - 0 views

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    The purpose of the American Heart Association/Allen Initiative in Brain Health and Cognitive Impairment is to discover and fund highly promising teams of investigators who can expand the frontiers of bioscience, pursuing creative, transformative ideas with the potential to move brain health and cognitive impairment science forward. The initiative will award up to $43 million over eight years to one or more highly inspiring and innovative integrated team(s) for large-scale integrated research that identifies novel, early, actionable, biological/mechanistic contributors to age-related cognitive impairment.

MiamiOH OARS

National Alzheimer's Call Center - 0 views

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    The Administration on Aging will hold a competition for a new cooperative agreement to continue operation of a national information and counseling service for persons with Alzheimer's disease, their family members and caregivers (National Alzheimer's Call Center). The National Call Center will be available to people in 56 states and territories, 24 hours a day, 7 days a week, 365 days a year to provide expert advice, care consultation, information and referrals at the national and local levels, regarding Alzheimer's disease and related dementias (ADRD).
MiamiOH OARS

Alzheimer's Disease Programs to States and Communities - 0 views

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    Cooperative agreements under this funding opportunity announcement (FOA), Alzheimer's Disease Program Initiative (ADPI), are dedicated to the development and expansion of dementia-capable home and community-based service (HCBS) systems in States and Communities. There are two application options contained in this FOA, one for States (Option A) and the other for Communities (Option B). No entity would be eligible to apply for both State and Community options. The systems resulting from program activities under both program options will provide quality, person-centered services that help individuals remain independent and safe in their communities.
MiamiOH OARS

RFA-AG-19-005: Collaborative Network to Advance Deprescribing Research for Older Adults... - 0 views

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    Deprescribing, the cessation of long-term therapy under clinician supervision, is a fundamental technique of geriatric practice and palliative medicine to address inappropriate medication use and/or polypharmacy common among older adults with multi-morbidity. Important research gaps remain whose resolution may improve approaches to deprescribing and may improve health outcomes by optimizing the goal-directed care of older adults with multiple chronic conditions. This FOA is intended to support a collaborative network to advance scientific research into techniques and outcomes of deprescribing medications for prevention and treatment of older adults with multiple chronic conditions. This network should address the scientific, safety, ethical, and logistical challenges of deprescribing trials and may incorporate focused attention to other relevant and well-justified topics, such as the risks and benefits of target medications, or alternative approaches that may substitute for the deprescribed drugs.
MiamiOH OARS

Collaborative Network to Advance Deprescribing Research for Older Adults with Multiple ... - 0 views

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    Deprescribing, the cessation of long-term therapy under clinician supervision, is a fundamental technique of geriatric practice and palliative medicine to address inappropriate medication use and/or polypharmacy common among older adults with multimorbidity. Important research gaps remain whose resolution may improve approaches to deprescribing and may improve health outcomes by optimizing the goal-directed care of older adults with multiple chronic conditions. This FOA is intended to support a collaborative network to advance scientific research into techniques and outcomes of deprescribing medications for prevention and treatment of older adults with multiple chronic conditions. This network should address the scientific, safety, ethical, and logistical challenges of deprescribing trials and may incorporate focused attention to other relevant and well-justified topics, such as the risks and benefits of target medications, or alternative approaches that may substitute for the deprescribed drugs. This FOA will support the establishment and initial operations of a network over the 5-year grant period including development of collaborations, resources, and infrastructure.
MiamiOH OARS

Tax Counseling for the Elderly - 0 views

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    The Tax Counseling for the Elderly (TCE) Program offers FREE tax help to individuals who are age 60 or older. Section 163 of the Revenue Act of 1978, Public Law No. 95-600, 92 Stat. 2810, November 6, 1978, authorizes this cooperative agreement. The Act authorizes the Internal Revenue Service (IRS) to enter into agreements with private or public nonprofit agencies and organizations, which will provide training and technical assistance to volunteers who provide FREE tax counseling and assistance to elderly individuals in the preparation of their federal income tax returns.
    This Act authorizes an appropriation of special funds, in the form of grants, to provide tax assistance to persons age 60 years of age or older. The IRS receives the funds as a line item in the budget appropriation. The total funds are distributed to the grant recipients for their expenses.
MiamiOH OARS

RFA-AG-19-002: Small Research Grant Program for the Next Generation of Clinical Researc... - 0 views

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    This Small Research Grant Program supports important and innovative research in areas in which more scientific investigation is needed to improve the prevention, diagnosis, treatment and care for Alzheimer's disease and related dementias (AD/ADRD). The program seeks (i) to facilitate the next generation of researchers in the United States to pursue research and academic careers in neurosciences, AD/ADRD and healthy brain aging, and (ii) to stimulate established researchers who are not currently doing AD/ADRD research to perform pilot studies toward developing new innovative AD/ADRD research programs that leverage and build upon their existing expertise. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
MiamiOH OARS

Drug Discovery Program | Alzheimer's Drug Discovery Foundation - 0 views

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    The Alzheimer's Drug Discovery Foundation has issued a Request for Proposals for its Preclinical Drug Discovery program.



    Through the program, grants of up to $600,000 over two years will be awarded to promising preclinical drug discovery programs relevant to Alzheimer's disease, related dementias, and cognitive aging. Preclinical research funding priorities include high throughput screening, medicinal chemistry hit-to-lead development and optimization, in vitro and in vivo efficacy studies, ADME, toxicology, pharma-cokinetics and pharma-co-dynamics, and in vivo proof-of-concept with lead compounds and biologics.
    Program areas of particular interest include new chemical compounds for Alzheimer's disease, preclinical proof-of-concept, and re-purposing. With regards to potential drug targets, ADDF is interested in novel targets that include but are not limited to neuro-inflammation, protein degradation/autophagy, growth factor signaling, synaptic function/morphology, calcium regulation, energy utilization/mitochondria function, insulin sensitivity, epigenetics, ApoE function and cholesterol metabolism, vascular injury and the blood-brain barrier interface, cognitive enhancers, myelin changes, ischemia and oxidative stress, and tau-related toxicities.
    To be eligible, applicants must be academic investigators seeking to create and support innovative translational programs in academic medical centers and universities; biotechnology companies with programs dedicated to Alzheimer's disease translational development; and new biotechnology company spinouts or existing biotechnology companies that demonstrate a clear need for nonprofit funding. Funding is provided through program-related investments (PRIs) that require a return on investment based on scientific and/or business milestones.
MiamiOH OARS

Small Research Grant Program for the Next Generation of Researchers in Basic Alzheimer'... - 0 views

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    This Small Research Grant Program supports important and innovative research in areas in which more scientific investigation is needed to improve the prevention, diagnosis, treatment and care for Alzheimer's disease and related dementias. The program seeks to stimulate the next generation of researchers in the United States to pursue research and academic careers in neurosciences, Alzheimer's disease and healthy brain aging.
MiamiOH OARS

Retirement and Disability Research Consortium - 0 views

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    As authorized under section 1110 of the Social Security Act, SSA announces the solicitation of applications for cooperative agreements to compete a Retirement and Disability Research Consortium (RDRC). SSA seeks applications in support of the RDRC that will continue to serve as a national resource fostering high quality research on matters related to retirement and disability policy. The Consortium may consist of one or more research "centers" - research organizations, universities, and associations of research organizations and universities in the United States that may include affiliates at other research institutions
MiamiOH OARS

PAR-18-760: In Vivo Synaptic Function in Alzheimers Disease and Related Dementias (R21 ... - 0 views

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    To study in vivo synaptic structure and function in Alzheimer's and related dementia; and to advance development of methods to study synapses in animal models and humans.
MiamiOH OARS

Limited Competition: Interaction of HIV Infection and Alcohol Abuse on Central Nervous ... - 0 views

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    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) invites applications to evaluate the cumulative and progressive effects on brain structure and cognitive/behavioral function of combined HIV infection and alcohol abuse on older patients cohorts.
MiamiOH OARS

In Vivo Synaptic Function in Alzheimers Disease and Related Dementias (R21 Clinical Tri... - 0 views

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    To study in vivo synaptic structure and function in Alzheimer's and related dementia; and to advance development of methods to study synapses in animal models and humans.
MiamiOH OARS

Broader Impacts 101 workshop | Miami University - 0 views

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    Presenter Liz Nysson will provide a general overview of broader impacts, including:

    The history of the National Science Foundation's broader impacts (BI) criterion
    Strategies for conceptualizing, developing, implementing, and evaluating BI activities
    Tips for leveraging existing resources to build a "BI identity"
MiamiOH OARS

UA6 Life Course Intervention Research Network (LCI-RN) - 0 views

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    The purpose of this program is to coordinate a national platform to support research studies to advance knowledge in disease prevention and health promotion across the life course by supporting a national network of interdisciplinary MCH researchers to design, plan, and implement multi-site life course intervention research studies
MiamiOH OARS

Innovations in Nutrition Programs and Services - 0 views

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    This funding opportunity is for competitive grants to be awarded under the OAA Title IV authority to increase the evidenced based knowledge base of nutrition providers, drive improved health outcomes for program recipients by promoting higher service quality, and increase program efficiency through innovative nutrition service delivery models. Funding will support innovative and promising practices that move the aging network towards evidenced based practices that enhance the quality, effectiveness of nutrition services programs or outcomes within the aging services network. Innovation can include service products that appeal to caregivers (such as web-based ordering systems and carryout food products), increased involvement of volunteers (such as retired chefs), consideration of eating habits and choice (such as variable meal times, salad bars, or more fresh fruits and vegetables), new service models (testing variations and hybrid strategies) and other innovations to better serve a generation of consumers whose needs and preferences are different. Innovative and promising practices may include the testing and publishing of positive outcomes in which nutrition programs provide a meaningful role in support of the health and long-term care of older individuals. Outcomes should focus on methods to improve collaboration with local health care entities, decrease health care costs for a specific population or decrease the incidence of the need for institutionalization among older adults. Through this program, funds may be used to help develop and test additional models or to replicate models that have already been tested in other community-based settings.
MiamiOH OARS

Brookdale Foundation Announces RFP for Respite and Relatives as Parents Programs | RFPs... - 0 views

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    In addition to providing respite care and enjoyable group activities that build on the strengths and abilities of participants, the programs offer family caregivers access to services such as counseling, support groups, information and referral, training, and education. With a nationwide network of programs providing regular respite services, the program demonstrates that a cost-effective social model of adult day services can successfully address the special needs of Alzheimer's families.
    To that end, grants of up to $15,000 will be awarded to up to fifteen Group Respite and Early Memory Loss programs to develop a new dementia-specific social model program. Grant funds may not be used to support or expand the hours, days, or service capacity of existing social, health, or medical model programs or to serve mixed populations.
    Applications must be received no later than June 27.
MiamiOH OARS

PA-18-751: Geriatrics and Clinical Gerontology Research to Address Health Disparities i... - 0 views

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    This Funding Opportunity Announcement (FOA) announces the availability of administrative supplements to support aging research that addresses disparities in health, with emphasis on geriatrics and clinical gerontology studies.
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