Applications to the Fiscal Year 2017 (FY17) Neurofibromatosis Research Program (NFRP) are being solicited by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The execution management agent for this Program Announcement is the Congressionally Directed Medical Research Programs (CDMRP). The NFRP was initiated in 1996 to provide support for research of exceptional scientific merit that promotes the understanding, diagnosis, and treatment of neurofibromatosis (NF) including NF type 1 (NF1) and type 2 (NF2) and schwannomatosis.
Applications to the Fiscal Year 2017 (FY17) Neurofibromatosis Research Program (NFRP) are being solicited by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The execution management agent for this Program Announcement is the Congressionally Directed Medical Research Programs (CDMRP). The NFRP was initiated in 1996 to provide support for research of exceptional scientific merit that promotes the understanding, diagnosis, and treatment of neurofibromatosis (NF) including NF type 1 (NF1) and type 2 (NF2) and schwannomatosis.
The Fiscal Year 2015 Department of Defense Appropriations Act provides research funding for the following peer reviewed programs managed by the Department of Defense office of Congressionally Directed Medical Research Programs (CDMRP):
Alcohol and Substance Abuse Research Program - $4.0 million
Amyotrophic Lateral Sclerosis Research Program - $7.5 million
Autism Research Program - $6.0 million
Bone Marrow Failure Research Program - $3.2 million
Breast Cancer Research Program - $120.0 million
Duchenne Muscular Dystrophy Research Program - $3.2 million
Epilepsy Research Program - $7.5 million
Gulf War Illness Research Program - $20.0 million
Joint Warfighter Medical Research Program - $50.0 million
Lung Cancer Research Program - $10.5 million
Military Burn Research Program - $8.0 million
Multiple Sclerosis Research Program - $5.0 million
Neurofibromatosis Research Program - $15.0 million
Neurotoxin Exposure Treatment Parkinson's Research Program - $16.0 million
Orthotics and Prosthetics Outcomes - $10.0 million
Ovarian Cancer Research Program - $20.0 million
Peer Reviewed Alzheimer's Research Program - $12.0 million
Peer Reviewed Cancer Research Program - $50.0 million
Peer Reviewed Medical Research Program - $247.5 million
Peer Reviewed Orthopaedic Research Program - $30.0 million
Prostate Cancer Research Program - $80.0 million
Spinal Cord Injury Research Program - $30.0 million
Tuberous Sclerosis Complex Research Program - $6.0 million
Vision Research Program - $10.0 million
The NFRP Exploration - Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in NF research. Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well- formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is encouraged, but not required.
The proposed research project should be innovative. Innovative research may introduce a novel paradigm, challenge existing paradigms, examine existing problems from novel perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of NF.
To allow investigators time to plan and develop applications, NFRP is providing its strategic plan for award mechanisms to be offered in 2013 should funding become available. Congressional funds for the FY13 NFRP have not yet been appropriated, and this document is not to be construed as an obligation by the government; there is no guarantee of funding for these planned mechanisms.
Areas of Emphasis: The FY13 NFRP encourages research projects applications that specifically address the critical needs of the NF community in the following areas of emphasis:
Cognitive and social dysfunction in the setting of NF;
Drug discovery for the treatment of NF;
Heterogeneity of neurofibromas and other NF-related tumors using genomics, epigenetics, systems biology, or other similar approaches;
Manifestations of NF post-adolescence;
Novel disease markers such as imaging and proteomics of NF;
Pain in the setting of NF.
The NFRP Exploration - Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in NF research. Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is encouraged, but not required.
The NFRP Exploration - Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in NF research. Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is encouraged, but not required.
The NFRP Investigator-Initiated Research Award supports highly rigorous, high-impact research projects that have the potential to make an important contribution to NF research and/or patient care. Research projects may focus on any phase of research, excluding clinical trials. The rationale for a research idea may be derived from laboratory discovery, population-based studies, a clinician's firsthand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to NF and the proposed research project.
The NFRP Exploration - Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in NF research. Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is encouraged, but not required. The proposed research project should be innovative. Innovative research may introduce a novel paradigm, challenge existing paradigms, examine existing problems from novel perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of NF.
Group items tagged 
