Therapeutic strategies aimed at preventing Aβ formation, blocking its aggregation into plaques, lowering its soluble levels in the brain, and disassembling existing amyloid plaques are among the main strategies employed to slow the progression of AD. Recently, a few therapeutic programs have aimed at reducing tau phosphorylation and/or aggregation. Beyond plaque- and tangle-related targets, other aspects of AD pathophysiology, including mitochondrial dysfunction, failure of molecular transport mechanisms, oxidative damage, inflammation, and cell-cycle dysregulation, may also provide therapeutic opportunities.
Rowley Rice on 17 Dec 09This popular source is an article from the Washington Times which discusses the problem of overmedication in the elderly. Interviews with doctors from hospitals across the country document the widespread issue. The elderly are often afflicted by many different conditions that require a diverse array of drug treatments. This often leads to drugs that combine for harsh side effects or which counter act each other. This was a very useful article in our blurb because it documents the problems that Mary Summer's husband experienced.
