Group items tagged

Review of patients treated with drug of dopenzil. Could be a primary source.

This 2009 research article is a detailed review of one FDA approved drug, Donepezil, to treat Alzheimer's Disease. The article outlines the background of Alzheimer's Disease, the methods of the study, the treatment of the drug, the results of the study, and further discussion on the patient group of the study. The article will be used as the main example of drug development in Alzheimer's Disease in the NPR-like blurb. Although this is the primary source, it will not suffice as the main focus of the blurb, which will be centered on the current drugs on the market and recent history in treatment for Alzheimer's Disease. Rather, this primary source will provide listeners with a specific example of the development and clinical research of one approved drug for Alzheimer's treatment.

Clinical trials overview for vaccine bapinezumab.

This primary source addresses "what's next" in drug development for the treatment of Alzheimer's. Specifically, this source is an overview of clinical trials for the Bapineuzumab vaccine that includes patients of different levels of cognitive impairment. This article helps shed light on biovariability and the fact that drugs' effectiveness depends on the individual.

Official Namenda website. Describes the biology of how the drug works to treat Alzheimer's.

This primary source is the official Namenda website, the brand name Memantine drug for the treatment of Alzheimer's disease. Because we discuss the two broad categories of drugs on the market for the treatment of Alzheimer's in our NPR-like blurb, one of which is Memantine, this article has been influential in our understanding the biology of how the drug works in treatment.

We chose this primary source in order to have a firm understanding of the causes, symptoms, and treatments of Alzheimer's disease. This article offers a brief summary of the two types of Alzheimer's, the early and late onset, the causes and other risk factors, the behavioral and physiological effects. There are also a list of exams and tests, which are necessary for different medical conditions that could be causing or exacerbating the disease. This source is a good reference for general information about Alzheimer's disease.

This articles helpfully analyzes the different mechanisms of action that current AD drugs use. This was helpful for the more science-focused part of our project. To comment on AD treatment it was necessary to learn a basic understanding of how the drugs work inside the body. We found that they used the same receptor based mechanism of action that the drugs we studied in class used.