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Weiye Loh

Our local Animation industry | the kent ridge common - 0 views

  • While many industrial veterans here put the blame solely on the “bo chap” attitudes of the students, I wish to point out the fact that those industrial veterans in the animation industry are just too afraid to admit that it was the fault of the tertiary education systems. It is true that while some students have an attitude problem, the lecturers in the polytechnics and universities have their fair share of the blame too. I also wish to speak up for students who have the passion for the industry but they are not shown the right path. Otherwise how do you explain that it took my mentor 2 years and only half the price of the poly fees to teach me all that I needed to know to find a job in the CG industry?
Weiye Loh

If Peas Can Talk, Should We Eat Them? - NYTimes.com - 0 views

  • growing fields of plant intelligence studies and neurobotany
  • . Is it morally permissible to submit to total instrumentalization living beings that, though they do not have a central nervous system, are capable of basic learning and communication? Should their swift response to stress leave us coldly indifferent, while animal suffering provokes intense feelings of pity and compassion?
  • When it comes to a plant, it turns out to be not only a what but also a who — an agent in its milieu, with its own intrinsic value or version of the good. Inquiring into justifications for consuming vegetal beings thus reconceived, we reach one of the final frontiers of dietary ethics.
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  • the subjectivity of plants is not centered in a single organ or function but is dispersed throughout their bodies, from the roots to the leaves and shoots. Nevertheless, this dispersion of vitality holds out a promise of its own: the plasticity of plants and their wondrous capacity for regeneration, their growth by increments, quantitative additions or reiterations of already existing parts does little to change the form of living beings that are neither parts nor wholes because they are not hierarchically structured organisms. The “renewable” aspects of perennial plants may be accepted by humans as a gift of vegetal being and integrated into their diets.
  • The desire to eat ethically is, perhaps, akin to this royal sensitivity, as some would argue that it is a luxury of those who do have enough food to select, in a conscious manner, their dietary patterns.
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    a pea plant subjected to drought conditions communicated its stress to other such plants, with which it shared its soil. In other words, through the roots, it relayed to its neighbors the biochemical message about the onset of drought, prompting them to react as though they, too, were in a similar predicament. Curiously, having received the signal, plants not directly affected by this particular environmental stress factor were better able to withstand adverse conditions when they actually occurred. This means that the recipients of biochemical communication could draw on their "memories" - information stored at the cellular level - to activate appropriate defenses and adaptive responses when the need arose.
Weiye Loh

Digital Domain - Computers at Home - Educational Hope vs. Teenage Reality - NYTimes.com - 0 views

  • MIDDLE SCHOOL students are champion time-wasters. And the personal computer may be the ultimate time-wasting appliance.
  • there is an automatic inclination to think of the machine in its most idealized form, as the Great Equalizer. In developing countries, computers are outfitted with grand educational hopes, like those that animate the One Laptop Per Child initiative, which was examined in this space in April.
  • Economists are trying to measure a home computer’s educational impact on schoolchildren in low-income households. Taking widely varying routes, they are arriving at similar conclusions: little or no educational benefit is found. Worse, computers seem to have further separated children in low-income households, whose test scores often decline after the machine arrives, from their more privileged counterparts.
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  • Professor Malamud and his collaborator, Cristian Pop-Eleches, an assistant professor of economics at Columbia University, did their field work in Romania in 2009, where the government invited low-income families to apply for vouchers worth 200 euros (then about $300) that could be used for buying a home computer. The program provided a control group: the families who applied but did not receive a voucher.
  • the professors report finding “strong evidence that children in households who won a voucher received significantly lower school grades in math, English and Romanian.” The principal positive effect on the students was improved computer skills.
  • few children whose families obtained computers said they used the machines for homework. What they were used for — daily — was playing games.
  • negative effect on test scores was not universal, but was largely confined to lower-income households, in which, the authors hypothesized, parental supervision might be spottier, giving students greater opportunity to use the computer for entertainment unrelated to homework and reducing the amount of time spent studying.
  • The North Carolina study suggests the disconcerting possibility that home computers and Internet access have such a negative effect only on some groups and end up widening achievement gaps between socioeconomic groups. The expansion of broadband service was associated with a pronounced drop in test scores for black students in both reading and math, but no effect on the math scores and little on the reading scores of other students.
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    Computers at Home: Educational Hope vs. Teenage Reality By RANDALL STROSS Published: July 9, 2010
Weiye Loh

Why Evolution May Favor Irrationality - Newsweek - 0 views

  • The reason we succumb to confirmation bias, why we are blind to counterexamples, and why we fall short of CartesianCartesian logic in so many other ways is that these lapses have a purpose: they help us “devise and evaluate arguments that are intended to persuade other people,” says psychologist Hugo Mercier of the University of Pennsylvania. Failures of logic, he and cognitive scientist Dan Sperber of the Institut Jean Nicod in Paris propose, are in fact effective ploys to win arguments.
  • That puts poor reasoning in a completely different light. Arguing, after all, is less about seeking truth than about overcoming opposing views.
  • while confirmation bias, for instance, may mislead us about what’s true and real, by letting examples that support our view monopolize our memory and perception, it maximizes the artillery we wield when trying to convince someone that, say, he really is “late all the time.” Confirmation bias “has a straightforward explanation,” argues Mercier. “It contributes to effective argumentation.”
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  • finding counterexamples can, in general, weaken our confidence in our own arguments. Forms of reasoning that are good for solving logic puzzles but bad for winning arguments lost out, over the course of evolution, to those that help us be persuasive but cause us to struggle with abstract syllogisms. Interestingly, syllogisms are easier to evaluate in the form “No flying things are penguins; all penguins are birds; so some birds are not fliers.” That’s because we are more likely to argue about animals than A, B, and C.
  • The sort of faulty thinking called motivated reasoning also impedes our search for truth but advances arguments. For instance, we tend to look harder for flaws in a study when we don’t agree with its conclusions and are more critical of evidence that undermines our point of view.
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    The Limits of Reason Why evolution may favor irrationality.
Weiye Loh

Sam Harris to Speak at 3 CFI Branches on U.S. Book Tour | Center for Inquiry - 1 views

  • Sam Harris’s first book, The End of Faith , ignited a worldwide debate about the validity of religion. In the aftermath, Harris discovered that most people—from religious fundamentalists to non-believing scientists—agree on one point: Science has nothing to say on the subject of human values. Indeed, our failure to address questions of meaning and morality through science has now become the most common justification for religious faith. It is also the primary reason why so many secularists and religious moderates feel obligated to “respect” the hardened superstitions of their more devout neighbors.
  • In this explosive new book, Sam Harris tears down the wall between scientific facts and human values, arguing that most people are simply mistaken about the relationship between morality and the rest of human knowledge. Harris urges us to think about morality in terms of human and animal well-being, viewing the experiences of conscious creatures as peaks and valleys on a “moral landscape.” Because there are definite facts to be known about where we fall on this landscape, Harris foresees a time when science will no longer limit itself to merely describing what people do in the name of “morality”; in principle, science should be able to tell us what we ought to do to live the best lives possible.
  • Harris demonstrates that we already know enough about the human brain and its relationship to events in the world to say that there are right and wrong answers to the most pressing questions of human life. Because such answers exist, moral relativism is simply false—and comes at increasing cost to humanity.
Weiye Loh

Paul Crowley's Blog - A survey of anti-cryonics writing - 0 views

  • cryonics offers almost eternal life. To its critics, cryonics is pseudoscience; the idea that we could freeze someone today in such a way that future technology might be able to re-animate them is nothing more than wishful thinking on the desire to avoid death. Many who battle nonsense dressed as science have spoken out against it: see for example Nano Nonsense and Cryonics, a 2001 article by celebrated skeptic Michael Shermer; or check the Skeptic’s Dictionary or Quackwatch entries on the subject, or for more detail read the essay Cryonics–A futile desire for everlasting life by “Invisible Flan”.
  • And of course the pro-cryonics people have written reams and reams of material such as Ben Best’s Scientific Justification of Cryonics Practice on why they think this is exactly as plausible as I might think, and going into tremendous technical detail setting out arguments for its plausibility and addressing particular difficulties. It’s almost enough to make you want to sign up on the spot. Except, of course, that plenty of totally unscientific ideas are backed by reams of scientific-sounding documents good enough to fool non-experts like me. Backed by the deep pockets of the oil industry, global warming denialism has produced thousands of convincing-sounding arguments against the scientific consensus on CO2 and AGW. T
  • Nano Nonsense and Cryonics goes for the nitty-gritty right away in the opening paragraph:To see the flaw in this system, thaw out a can of frozen strawberries. During freezing, the water within each cell expands, crystallizes, and ruptures the cell membranes. When defrosted, all the intracellular goo oozes out, turning your strawberries into runny mush. This is your brain on cryonics.This sounds convincing, but doesn’t address what cryonicists actually claim. Ben Best, President and CEO of the Cryonics Institute, replies in the comments:Strawberries (and mammalian tissues) are not turned to mush by freezing because water expands and crystallizes inside the cells. Water crystallizes in the extracellular space because more nucleators are found extracellularly. As water crystallizes in the extracellular space, the extracellular salt concentration increases causing cells to lose water osmotically and shrink. Ultimately the cell membranes are broken by crushing from extracellular ice and/or high extracellular salt concentration. […] Cryonics organizations use vitrification perfusion before cooling to cryogenic temperatures. With good brain perfusion, vitrification can reduce ice formation to negligible amounts.
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  • The Skeptic’s Dictionary entry is no advance. Again, it refers erroneously to a “mushy brain”. It points out that the technology to reanimate those in storage does not already exist, but provides no help for us non-experts in assessing whether it is a plausible future technology, like super-fast computers or fusion power, or whether it is as crazy as the sand-powered tank; it simply asserts baldly and to me counterintuitively that it is the latter. Again, perhaps cryonic reanimation is a sand-powered tank, but I can explain to you why a sand-powered tank is implausible if you don’t already know, and if cryonics is in the same league I’d appreciate hearing the explanation.
  • Another part of the article points out the well-known difficulties with whole-body freezing — because the focus is on achieving the best possible preservation of the brain, other parts suffer more. But the reason why the brain is the focus is that you can afford to be a lot bolder in repairing other parts of the body — unlike the brain, if my liver doesn’t survive the freezing, it can be replaced altogether.
  • Further, the article ignores one of the most promising possibilities for reanimation, that of scanning and whole-brain emulation, a route that requires some big advances in computer and scanning technology as well as our understanding of the lowest levels of the brain’s function, but which completely sidesteps any problems with repairing either damage from the freezing process or whatever it was that led to legal death.
  • Sixteen years later, it seems that hasn’t changed; in fact, as far as the issue of technical feasability goes it is starting to look as if on all the Earth, or at least all the Internet, there is not one person who has ever taken the time to read and understand cryonics claims in any detail, still considers it pseudoscience, and has written a paper, article or even a blog post to rebut anything that cryonics advocates actually say. In fact, the best of the comments on my first blog post on the subject are already a higher standard than anything my searches have turned up.
  • I don’t have anything useful to add, I just wanted to say that I feel exactly as you do about cryonics and living forever. And I thought that this statement: I know that I don’t know enough to judge. shows extreme wisdom. If only people wishing to comment on global warming would apply the same test.
  • WRT global warming, the mistake people make is trying to go direct to the first-order evidence, which is much too complicated and too easy to misrepresent to hope to directly interpret unless you make it your life’s work, and even then only in a particular area. The correct thing to do is to collect second-order evidence, such as that every major scientific academy has backed the IPCC.
    • Weiye Loh
       
      First-order evidence vs second-order evidence...
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    Cryonics
Weiye Loh

Morality, with limits | Russell Blackford | Comment is free | guardian.co.uk - 0 views

  • What can Darwin teach us about morality?At least to some extent, we are a species with an evolved psychology. Like other animals, we have inherited behavioural tendencies from our ancestors, since these were adaptive for them in the sense that they tended to lead to reproductive success in past environments.
  • But what follows from this?
  • we are not evolution's slaves. All other things being equal, we should act in accordance with the desires that we actually have
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  • Generally speaking, it is rational for us to act in ways that accord with our reflectively-endorsed desires or values, rather than in ways that maximise our reproductive chances or in whatever ways we tend to respond without thinking.
  • Admittedly, our evolved nature may affect this, in the sense that any workable system of moral norms must be practical for the needs of beings like us, who are, it seems, naturally inclined to be neither angelically selfless nor utterly uncaring about others.
  • our evolved psychology may impose limits on what real-world moral systems can realistically demand of human beings, perhaps defeating some of the more extreme ambitions of both conservatives and liberals. It may not be realistic to expect each other to be either as self-denying as moral conservatives seem to want or as altruistic as some liberals seem to want.
  • realistic moral systems will allow considerable scope for individuals to act in accordance with whatever they actually value.
  • A rational and realistic approach to morality, based on our actual, reflectively-endorsed desires and values, and how they are best realised in current circumstances, might deflate some expectations. It might also diverge from familiar moral teachings, handed down through religious and cultural traditions. Much that is found in traditional Christian morality
  • But realising all this need not be shocking. If it leads to some deflation of extreme political expectations and to some reason-based correction of traditional morality, we should welcome it.
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    Morality, with limits We can't expect people to be either as self-denying as conservatives or as altruistic as liberals seem to want
Weiye Loh

IPhone and Android Apps Breach Privacy - WSJ.com - 0 views

  • Few devices know more personal details about people than the smartphones in their pockets: phone numbers, current location, often the owner's real name—even a unique ID number that can never be changed or turned off.
  • An examination of 101 popular smartphone "apps"—games and other software applications for iPhone and Android phones—showed that 56 transmitted the phone's unique device ID to other companies without users' awareness or consent. Forty-seven apps transmitted the phone's location in some way. Five sent age, gender and other personal details to outsiders.
  • The findings reveal the intrusive effort by online-tracking companies to gather personal data about people in order to flesh out detailed dossiers on them.
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  • iPhone apps transmitted more data than the apps on phones using Google Inc.'s Android operating system. Because of the test's size, it's not known if the pattern holds among the hundreds of thousands of apps available.
  • TextPlus 4, a popular iPhone app for text messaging. It sent the phone's unique ID number to eight ad companies and the phone's zip code, along with the user's age and gender, to two of them.
  • Pandora, a popular music app, sent age, gender, location and phone identifiers to various ad networks. iPhone and Android versions of a game called Paper Toss—players try to throw paper wads into a trash can—each sent the phone's ID number to at least five ad companies. Grindr, an iPhone app for meeting gay men, sent gender, location and phone ID to three ad companies.
  • iPhone maker Apple Inc. says it reviews each app before offering it to users. Both Apple and Google say they protect users by requiring apps to obtain permission before revealing certain kinds of information, such as location.
  • The Journal found that these rules can be skirted. One iPhone app, Pumpkin Maker (a pumpkin-carving game), transmits location to an ad network without asking permission. Apple declines to comment on whether the app violated its rules.
  • With few exceptions, app users can't "opt out" of phone tracking, as is possible, in limited form, on regular computers. On computers it is also possible to block or delete "cookies," which are tiny tracking files. These techniques generally don't work on cellphone apps.
  • makers of TextPlus 4, Pandora and Grindr say the data they pass on to outside firms isn't linked to an individual's name. Personal details such as age and gender are volunteered by users, they say. The maker of Pumpkin Maker says he didn't know Apple required apps to seek user approval before transmitting location. The maker of Paper Toss didn't respond to requests for comment.
  • Many apps don't offer even a basic form of consumer protection: written privacy policies. Forty-five of the 101 apps didn't provide privacy policies on their websites or inside the apps at the time of testing. Neither Apple nor Google requires app privacy policies.
  • the most widely shared detail was the unique ID number assigned to every phone.
  • On iPhones, this number is the "UDID," or Unique Device Identifier. Android IDs go by other names. These IDs are set by phone makers, carriers or makers of the operating system, and typically can't be blocked or deleted. "The great thing about mobile is you can't clear a UDID like you can a cookie," says Meghan O'Holleran of Traffic Marketplace, an Internet ad network that is expanding into mobile apps. "That's how we track everything."
  • O'Holleran says Traffic Marketplace, a unit of Epic Media Group, monitors smartphone users whenever it can. "We watch what apps you download, how frequently you use them, how much time you spend on them, how deep into the app you go," she says. She says the data is aggregated and not linked to an individual.
  • Apple and Google ad networks let advertisers target groups of users. Both companies say they don't track individuals based on the way they use apps.
  • Apple limits what can be installed on an iPhone by requiring iPhone apps to be offered exclusively through its App Store. Apple reviews those apps for function, offensiveness and other criteria.
  • Apple says iPhone apps "cannot transmit data about a user without obtaining the user's prior permission and providing the user with access to information about how and where the data will be used." Many apps tested by the Journal appeared to violate that rule, by sending a user's location to ad networks, without informing users. Apple declines to discuss how it interprets or enforces the policy.
  • Google doesn't review the apps, which can be downloaded from many vendors. Google says app makers "bear the responsibility for how they handle user information." Google requires Android apps to notify users, before they download the app, of the data sources the app intends to access. Possible sources include the phone's camera, memory, contact list, and more than 100 others. If users don't like what a particular app wants to access, they can choose not to install the app, Google says.
  • Neither Apple nor Google requires apps to ask permission to access some forms of the device ID, or to send it to outsiders. When smartphone users let an app see their location, apps generally don't disclose if they will pass the location to ad companies.
  • Lack of standard practices means different companies treat the same information differently. For example, Apple says that, internally, it treats the iPhone's UDID as "personally identifiable information." That's because, Apple says, it can be combined with other personal details about people—such as names or email addresses—that Apple has via the App Store or its iTunes music services. By contrast, Google and most app makers don't consider device IDs to be identifying information.
  • A growing industry is assembling this data into profiles of cellphone users. Mobclix, the ad exchange, matches more than 25 ad networks with some 15,000 apps seeking advertisers. The Palo Alto, Calif., company collects phone IDs, encodes them (to obscure the number), and assigns them to interest categories based on what apps people download and how much time they spend using an app, among other factors. By tracking a phone's location, Mobclix also makes a "best guess" of where a person lives, says Mr. Gurbuxani, the Mobclix executive. Mobclix then matches that location with spending and demographic data from Nielsen Co.
  • Mobclix can place a user in one of 150 "segments" it offers to advertisers, from "green enthusiasts" to "soccer moms." For example, "die hard gamers" are 15-to-25-year-old males with more than 20 apps on their phones who use an app for more than 20 minutes at a time. Mobclix says its system is powerful, but that its categories are broad enough to not identify individuals. "It's about how you track people better," Mr. Gurbuxani says.
  • four app makers posted privacy policies after being contacted by the Journal, including Rovio Mobile Ltd., the Finnish company behind the popular game Angry Birds (in which birds battle egg-snatching pigs). A spokesman says Rovio had been working on the policy, and the Journal inquiry made it a good time to unveil it.
  • Free and paid versions of Angry Birds were tested on an iPhone. The apps sent the phone's UDID and location to the Chillingo unit of Electronic Arts Inc., which markets the games. Chillingo says it doesn't use the information for advertising and doesn't share it with outsiders.
  • Some developers feel pressure to release more data about people. Max Binshtok, creator of the DailyHoroscope Android app, says ad-network executives encouraged him to transmit users' locations. Mr. Binshtok says he declined because of privacy concerns. But ads targeted by location bring in two to five times as much money as untargeted ads, Mr. Binshtok says. "We are losing a lot of revenue."
  • Apple targets ads to phone users based largely on what it knows about them through its App Store and iTunes music service. The targeting criteria can include the types of songs, videos and apps a person downloads, according to an Apple ad presentation reviewed by the Journal. The presentation named 103 targeting categories, including: karaoke, Christian/gospel music, anime, business news, health apps, games and horror movies. People familiar with iAd say Apple doesn't track what users do inside apps and offers advertisers broad categories of people, not specific individuals. Apple has signaled that it has ideas for targeting people more closely. In a patent application filed this past May, Apple outlined a system for placing and pricing ads based on a person's "web history or search history" and "the contents of a media library." For example, home-improvement advertisers might pay more to reach a person who downloaded do-it-yourself TV shows, the document says.
  • The patent application also lists another possible way to target people with ads: the contents of a friend's media library. How would Apple learn who a cellphone user's friends are, and what kinds of media they prefer? The patent says Apple could tap "known connections on one or more social-networking websites" or "publicly available information or private databases describing purchasing decisions, brand preferences," and other data. In September, Apple introduced a social-networking service within iTunes, called Ping, that lets users share music preferences with friends. Apple declined to comment.
Weiye Loh

Search Optimization and Its Dirty Little Secrets - NYTimes.com - 0 views

  • Mr. Stevens turned out to be a boyish-looking 31-year-old native of Singapore. (Stevens is the name he uses for work; he says he has a Chinese last name, which he did not share.) He speaks with a slight accent and in an animated hush, like a man worried about eavesdroppers. He describes his works with the delighted, mischievous grin of a sophomore who just hid a stink bomb.
  • “The key is to roll the campaign out slowly,” he said as he nibbled at seared duck foie gras. “A lot of companies are in a rush. They want as many links as we can get them as fast as possible. But Google will spot that. It will flag a Web site that goes from zero links to a few hundred in a week.”
  • The hardest part about the link-selling business, he explained, is signing up deep-pocketed mainstream clients. Lots of them, it seems, are afraid they’ll get caught. Another difficulty is finding quality sites to post links. Whoever set up the JCPenney.com campaign, he said, relied on some really low-rent, spammy sites — the kind with low PageRanks, as Google calls its patented measure of a site’s quality. The higher the PageRank, the more “Google juice” a site offers others to which it is linked.
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  • Mr. Stevens said that Web site owners, or publishers, as he calls them, get a small fee for each link, and the transaction is handled entirely over the Web. Publishers can reject certain keywords and links — Mr. Stevens said some balked at a lingerie link — but for the most part the system is on a kind of autopilot. A client pays Mr. Stevens and his colleagues for links, which are then farmed out to Web sites. Payment to publishers is handled via PayPal.
  • You might expect Mr. Stevens to have a certain amount of contempt for Google, given that he spends his professional life finding ways to subvert it. But through the evening he mentioned a few times that he’s in awe of the company, and the quality of its search engine.
  • “I think we need to make a distinction between two different kinds of searches — informational and commercial,” he said. “If you search ‘cancer,’ that’s an informational search and on those, Google is amazing. But in commercial searches, Google’s results are really polluted. My own personal experience says that the guy with the biggest S.E.O. budget always ranks the highest.”
  • To Mr. Stevens, S.E.O. is a game, and if you’re not paying black hats, you are losing to rivals with fewer compunctions.
  • WHY did Google fail to catch a campaign that had been under way for months? One, no less, that benefited a company that Google had already taken action against three times? And one that relied on a collection of Web sites that were not exactly hiding their spamminess? Mr. Cutts emphasized that there are 200 million domain names and a mere 24,000 employees at Google.
Weiye Loh

Studying the politics of online science « through the looking glass - 0 views

  • Mendick, H. and Moreau, M. (2010). Monitoring the presence and representation of  women in SET occupations in UK based online media. Bradford: The UKRC.
  • Mendick and Moreau considered the representation of women on eight ‘SET’ (science, engineering and technology) websites: New Scientist, Bad Science, the Science Museum, the Natural History Museum, Neuroskeptic, Science: So What, Watt’s Up With That and RichardDawkins.net. They also monitored SET content across eight more general sites: the BBC, Channel 4, Sky, the Guardian, the Daily Mail, Wikipedia, YouTube and Twitter.
  • Their results suggest online science informational content is male dominated in that far more men than women are present. On some websites, they found no SET women. All of the 14 people in SET identified on the sampled pages of the RichardDawkins.net website were men, and so were all 29 of those mentioned on the sampled pages of the Channel 4 website (Mendick & Moreau, 2010: 11).
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  • They found less hyperlinking of women’s than men’s names (Mendick & Moreau, 2010: 7). Personally, I’d have really liked some detail as to how they came up with this, and what constituted ‘hyperlinking of women’s names’ precisely. It’s potentially an interesting finding, but I can’t quite get a grip on what they are saying.
  • They also note that the women that did appear, they were often peripheral to the main story, or ‘subject to muting’ (i.e. seen but not heard). They also noted many instances where women were pictured but remain anonymous, as if there are used to illustrate a piece – for ‘ornamental’ purposes – and give the example of the wikipedia entry on scientists, which includes a picture a women as an example, but stress she is anonymous (Mendick & Moreau, 2010: 12).
  • Echoing findings of earlier research on science in the media (e.g. the Bimbo or Boffin paper), they noted that women, when represented, tended to be associated with ‘feminine’ attributes and activities, demonstrating empathy with children and animals, etc. They also noted a clustering in specific fields. For example, in the pages they’d sampled of the Guardian, they found seven mentions of women scientists compared with twenty-eight of men, and three of the these women were in a single article, about Jane Goodall (Mendick & Moreau, 2010: 12-13).
  • The women presented were often discussed in terms of appearance, personality, sexuality and personal circumstances, again echoing previous research. They also noted that women scientists, when present, tended to be younger than the men, and there was a striking lack of ethnic diversity (Mendick & Moreau, 2010: 14).
  • I’m going to be quite critical of this research. It’s not actively bad, it just seems to lack depth and precision. I suspect Mendick and Moreau were doing their best with low resources and an overly-broad brief. I also think that we are still feeling our way in terms of working out how to study online science media, and so can learn something from such a critique.
  • Problem number one: it’s a small study, and yet a ginormous topic. I’d much rather they had looked at less, but made more of it. At times I felt like I was reading a cursory glance at online science.
  • Problem number two: the methodological script seemed a bit stuck in the print era. I felt the study lacked a feel for the variety of routes people take through online science. It lacked a sense of online science’s communities and cliques, its cultures and sub-cultures, its history and its people. It lacked context. Most of all, it lacked a sense of what I think sits at the center of online communication: the link.
  • It tries to look at too much, too quickly. We’re told that of the blog entries sampled from Bad Science, three out of four of the women mentioned were associated with ‘bad science’, compared to 12 out of 27 of the men . They follow up this a note that Goldacre has appeared on television critiquing Greenfield,­ a clip of which is on his site (Mendick & Moreau, 2010: 17-18). OK, but ‘bad’ needs unpacking here, as does the gendered nature of the area Goldacre takes aim at. As for Susan Greenfield, she is a very complex character when it comes to the politics of science and gender (one I’d say it is dangerous to treat representations of simplistically). Moreover, this is a very small sample, without much feel for the broader media context the Bad Science blog works within, including not only other platforms for Ben Goldacre’s voice but comment threads, forums and a whole community of other ‘bad science bloggers’ (and their relationships with each other)
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    okmark
Weiye Loh

News Clips: Pinning down acupuncture: It's a placebo - 0 views

  • some doctors seem to have embraced even disproven remedies. Take, for instance, a review of acupuncture research that appeared last July in the New England Journal of Medicine. This highly respected journal is one of the most widely read by doctors across specialities.In Acupuncture For Chronic Low Back Pain, the authors reviewed clinical trials done to assess if acupuncture actually helps in chronic low back pain. The most important meta-analysis available was a 2008 study involving 6,359 patients, which 'showed that real acupuncture treatments were no more effective than sham acupuncture treatments'.
  • The authors then editorialised: 'There was nevertheless evidence that both real acupuncture and sham acupuncture were more effective than no treatment and that acupuncture can be a useful supplement to other forms of conventional therapy for low back pain.'
  • First, they admit that pooled clinical trials of the best sort show that real acupuncture does no better than sham acupuncture. This should mean that acupuncture does not work - full stop. But then they say that both sham and real acupuncture work as well as the other and thus is useful. Translation: Please use acupuncture as a placebo on your patients; just don't let them know it is a placebo.
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  • I should add that I am not criticising TCM per se. Only acupuncture, a facet of TCM, albeit its most dramatic, is being scrutinised here. Chinese herbology must be analysed on its own merits.Interestingly, although acupuncture may be TCM's poster boy today, the Chinese physician in days of yore would have looked askance at it. Instead, his practice and prestige were based upon his grasp of the Chinese pharmacopoeia.
  • Acupuncture was left to the shamans and blood letters. After all, it was grounded, not in the knowledge of which herbs were best for what conditions, but astrology.
  • In Giovanni Maciocia's 2005 book, The Foundations Of Chinese Medicine: A Comprehensive Text For Acupuncturists And Herbalists, there is a chart showing the astrological provenance of acupuncture. The chart shows how the 12 main acupuncture meridians and the 12 main body segments correspond to the 12 Houses of the Chinese zodiac.
  • In Chinese cosmology, all life is animated by a numinous force called qi, the flow of which mirrors the sun's apparent 'movement' during the year through the ecliptic. (The ecliptic is the imaginary plane of the earth's orbit around the sun).Moreover, everything in the Chinese zodiac is mirrored on Earth and in Man. This was taught even in the earliest systematised TCM text, the Yellow Emperor's Canon Of Medicine, thus: 'Heaven is covered with constellations, Earth with waterways, and man with channels.'This 'as above, so below' doctrine means that if there is qi flowing around in the imaginary closed loop of the zodiac, there is qi flowing correspondingly in the body's closed loop of imaginary meridians as well.
  • Note that not only is acupuncture astrological in origin but also the astrology is based on a model of the universe which has the earth at its centre. This geocentric model was an erroneous idea widely accepted before the Copernican revolution.
  • So should doctors check the daily horoscopes of their patients?
Weiye Loh

The world through language » Scienceline - 0 views

  • If you know only one language, you live only once. A man who knows two languages is worth two men. He who loses his language loses his world. (Czech, French and Gaelic proverbs.)
  • The hypothesis first put forward fifty years ago by linguist Benjamin Lee Whorf—that our language significantly affects our experience of the world—is making a comeback in various forms, and with it no shortage of debate.
  • The idea that language shapes thought was taboo for a long time, said Dan Slobin, a psycholinguist at the University of California, Berkeley. “Now the ice is breaking.” The taboo, according to Slobin, was largely due to the widespread acceptance of the ideas of Noam Chomsky, one of the most influential linguists of the 20th century. Chomsky proposed that the human brain comes equipped at birth with a set of rules—or universal grammar—that organizes language. As he likes to say, a visiting Martian would conclude that everyone on Earth speaks mutually unintelligible dialects of a single language.
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  • Chomsky is hesitant to accept the recent claims of language’s profound influence on thought. “I’m rather skeptical about all of this, though there probably are some marginal effects,” he said.
  • Some advocates of the Whorfian view find support in studies of how languages convey spatial orientation. English and Dutch speakers describe orientation from an egocentric frame of reference (to my left or right). Mayan speakers use a geocentric frame of reference (to the north or south).
  • Does this mean they think about space in fundamentally different ways? Not exactly, said Lila Gleitman, a psychologist from the University of Pennsylvania. Since we ordinarily assume that others talk like us, she explained, vague instructions like “arrange it the same way” will be interpreted in whatever orientation (egocentric or geocentric) is most common in our language. “That’s going to influence how you solve an ambiguous problem, but it doesn’t mean that’s the way you think, or must think,” said Gleitman. In fact, she repeated the experiment with unambiguous instructions, providing cues to indicate whether objects should be arranged north-south or left-right. She found that people in both languages are just as good at arranging objects in either orientation.
  • Similarly, Anna Papafragou, a psychologist at the University of Delaware, thinks that the extent of language’s effect on thought has been somewhat exaggerated.
  • Papafragou compared how long Greek and English speakers paid attention to clip-art animation sequences, for example, a man skating towards a snowman. By measuring their eye movements, Papafragou was able to tell which parts of the scene held their gaze the longest. Because English speakers generally use verbs that describe manner of motion, like slide and skip, she predicted they would pay more attention to what was moving (the skates). Since Greeks use verbs that describe path, like approach and ascend, they should pay more attention to endpoint of the motion (the snowman). She found that this was true only when people had to describe the scene; when asked to memorize it, attention patterns were nearly identical. According to Papafragou, when people need to speak about what they see, they’ll focus on the parts relevant for planning sentences. Otherwise, language does not show much of an effect on attention.
  • “Each language is a bright transparent medium through which our thoughts may pass, relatively undistorted,” said Gleitman.
  • Others think that language does, in fact, introduce some distortion. Linguist Guy Deutscher of the University of Manchester in the U.K. suggests that while language can’t prevent you from thinking anything, it does compel you to think in specific ways. Language forces you to habitually pay attention to different aspects of the world.
  • For example, many languages assign genders to nouns (“bridge” is feminine in German and masculine in Spanish). A study by cognitive psychologist Lera Boroditsky of Stanford University found that German speakers were more likely to describe “bridge” with feminine terms like elegant and slender, while Spanish speakers picked words like sturdy and towering. Having to constantly keep track of gender, Deutscher suggests, may subtly change the way native speakers imagine object’s characteristics.
  • However, this falls short of the extreme view some ascribe to Whorf: that language actually determines thought. According to Steven Pinker, an experimental psychologist and linguist at Harvard University, three things have to hold for the Whorfian hypothesis to be true: speakers of one language should find it nearly impossible to think like speakers of another language; the differences in language should affect actual reasoning; and the differences should be caused by language, not just correlated with it. Otherwise, we may just be dealing with a case of “crying Whorf.”
  • But even mild claims may reveal complexities in the relationship between language and thought. “You can’t actually separate language, thought and perception,” said Debi Roberson, a psychologist at the University of Essex in the U.K. “All of these processes are going on, not just in parallel, but interactively.”
  • Language may not, as the Gaelic proverb suggests, form our entire world. But it will continue to provide insights into our thoughts—whether as a window, a looking glass, or a distorted mirror.
Weiye Loh

Rationally Speaking: Double podcast teaser! Vegetarianism and the relationship between ... - 0 views

  • Vegetarianism: is it a good idea? Vegetarianism is a complex set of beliefs and practices, spanning from the extreme “fruitarianism,” where people only eat fruits and other plant parts that can be gathered without “harming” the plant (though I’m sure the plant would rather keep its fruits and use them for the evolutionary purpose of dispersing its own offspring) to various forms of “flexitaranism,” like pollotarianism (poultry is okay to eat) and pescetarianism (fisk okay).
  • Is it true that a vegetarian diet increases one’s health? Yes, but only in certain respects, partially because vegetarians also tend to be health conscious in general (they exercise, don’t smoke, drink less, etc.), and it is not the case for the more extreme versions (including veganism), where one needs to be extremely careful to achieve a balanced diet which may need to be supplemented artificially, especially for growing children.
  • What is the ethical case for vegetarianism? Again, the answer is complex. It seems hard to logically defend fruitarianism, and borderline to make a moral argument for veganism, but broader forms of vegetarianism certainly get at important issues of suffering and mistreatment of both animals and industry workers, not to mention that the environmental impact of meat eating is much more damaging than that of vegetarianism. And so the debate rages on.
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  • Value-free science? Many scientists think that science is about objectivity and “just the facts, ma’am.” Not so fast, philosophers, historians and sociologists of science have argued now for a number of decades. While I certainly have no sympathy for the extreme postmodernist position exemplified by the so-called “strong programme” in sociology of science — that science is entirely the result of social construction — there are several interesting and delicate facets of the problem to explore.
  • there are values embedded in the practice of science itself: testability, accuracy, generality, simplicity, and the like. Needless to say, few if any of these can be justified within science itself — there is no experiment confirming Occam’s razor, for instance.
  • Then there are the many moral dimensions of science practice, both in terms of ethical issues internal to science (fraud) and of the much broader ones affecting society at large (societal consequences of research and technological advances).
  • There is also the issue of diversity in science. Until very recently, and in many fields still today, science has largely been an affair conducted by white males. And this has historically resulted in a large amount of nonsense — say about gender differences, or ethnic differences — put forth as objective knowledge and accepted by the public because it has the imprimatur of science. But, you might say, that was the past, now we have corrected the errors and moved on. Except that such an argument ignores the fact that there is little reason to think that only we have gotten it just right, that the current generation is somehow immune from an otherwise uninterrupted history of science-based blunders.
  • Regarding Occam's Razor, there is a justification for it based on probability theory, see:http://www.johndcook.com/blog/2011/01/12/occams-razor-bayes-theorem/http://telescoper.wordpress.com/2011/02/19/bayes-razor/http://www.stat.duke.edu/~berger/papers/ockham.html
  • another interesting dimension of the relationship between values and science concerns which scientific questions we should pursue (and, often, fund with public money). Scientists often act as they ought to be the only arbiters here, and talk as if some questions were “obviously” intrinsically important. But when your research is costly and paid for by the public, perhaps society deserves a bit more of an explanation concerning why millions of dollars ought to be spent on obscure problems that apparently interest only a handful of university professors concentrated in one or a few countries.
Weiye Loh

Skepticblog » A Creationist Challenge - 0 views

  • The commenter starts with some ad hominems, asserting that my post is biased and emotional. They provide no evidence or argument to support this assertion. And of course they don’t even attempt to counter any of the arguments I laid out. They then follow up with an argument from authority – he can link to a PhD creationist – so there.
  • The article that the commenter links to is by Henry M. Morris, founder for the Institute for Creation Research (ICR) – a young-earth creationist organization. Morris was (he died in 2006 following a stroke) a PhD – in civil engineering. This point is irrelevant to his actual arguments. I bring it up only to put the commenter’s argument from authority into perspective. No disrespect to engineers – but they are not biologists. They have no expertise relevant to the question of evolution – no more than my MD. So let’s stick to the arguments themselves.
  • The article by Morris is an overview of so-called Creation Science, of which Morris was a major architect. The arguments he presents are all old creationist canards, long deconstructed by scientists. In fact I address many of them in my original refutation. Creationists generally are not very original – they recycle old arguments endlessly, regardless of how many times they have been destroyed.
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  • Morris also makes heavy use of the “taking a quote out of context” strategy favored by creationists. His quotes are often from secondary sources and are incomplete.
  • A more scholarly (i.e. intellectually honest) approach would be to cite actual evidence to support a point. If you are going to cite an authority, then make sure the quote is relevant, in context, and complete.
  • And even better, cite a number of sources to show that the opinion is representative. Rather we get single, partial, and often outdated quotes without context.
  • (nature is not, it turns out, cleanly divided into “kinds”, which have no operational definition). He also repeats this canard: Such variation is often called microevolution, and these minor horizontal (or downward) changes occur fairly often, but such changes are not true “vertical” evolution. This is the microevolution/macroevolution false dichotomy. It is only “often called” this by creationists – not by actual evolutionary scientists. There is no theoretical or empirical division between macro and micro evolution. There is just evolution, which can result in the full spectrum of change from minor tweaks to major changes.
  • Morris wonders why there are no “dats” – dog-cat transitional species. He misses the hierarchical nature of evolution. As evolution proceeds, and creatures develop a greater and greater evolutionary history behind them, they increasingly are committed to their body plan. This results in a nestled hierarchy of groups – which is reflected in taxonomy (the naming scheme of living things).
  • once our distant ancestors developed the basic body plan of chordates, they were committed to that body plan. Subsequent evolution resulted in variations on that plan, each of which then developed further variations, etc. But evolution cannot go backward, undo evolutionary changes and then proceed down a different path. Once an evolutionary line has developed into a dog, evolution can produce variations on the dog, but it cannot go backwards and produce a cat.
  • Stephen J. Gould described this distinction as the difference between disparity and diversity. Disparity (the degree of morphological difference) actually decreases over evolutionary time, as lineages go extinct and the surviving lineages are committed to fewer and fewer basic body plans. Meanwhile, diversity (the number of variations on a body plan) within groups tends to increase over time.
  • the kind of evolutionary changes that were happening in the past, when species were relatively undifferentiated (compared to contemporary species) is indeed not happening today. Modern multi-cellular life has 600 million years of evolutionary history constraining their future evolution – which was not true of species at the base of the evolutionary tree. But modern species are indeed still evolving.
  • Here is a list of research documenting observed instances of speciation. The list is from 1995, and there are more recent examples to add to the list. Here are some more. And here is a good list with references of more recent cases.
  • Next Morris tries to convince the reader that there is no evidence for evolution in the past, focusing on the fossil record. He repeats the false claim (again, which I already dealt with) that there are no transitional fossils: Even those who believe in rapid evolution recognize that a considerable number of generations would be required for one distinct “kind” to evolve into another more complex kind. There ought, therefore, to be a considerable number of true transitional structures preserved in the fossils — after all, there are billions of non-transitional structures there! But (with the exception of a few very doubtful creatures such as the controversial feathered dinosaurs and the alleged walking whales), they are not there.
  • I deal with this question at length here, pointing out that there are numerous transitional fossils for the evolution of terrestrial vertebrates, mammals, whales, birds, turtles, and yes – humans from ape ancestors. There are many more examples, these are just some of my favorites.
  • Much of what follows (as you can see it takes far more space to correct the lies and distortions of Morris than it did to create them) is classic denialism – misinterpreting the state of the science, and confusing lack of information about the details of evolution with lack of confidence in the fact of evolution. Here are some examples – he quotes Niles Eldridge: “It is a simple ineluctable truth that virtually all members of a biota remain basically stable, with minor fluctuations, throughout their durations. . . .“ So how do evolutionists arrive at their evolutionary trees from fossils of organisms which didn’t change during their durations? Beware the “….” – that means that meaningful parts of the quote are being omitted. I happen to have the book (The Pattern of Evolution) from which Morris mined that particular quote. Here’s the rest of it: (Remember, by “biota” we mean the commonly preserved plants and animals of a particular geological interval, which occupy regions often as large as Roger Tory Peterson’s “eastern” region of North American birds.) And when these systems change – when the older species disappear, and new ones take their place – the change happens relatively abruptly and in lockstep fashion.”
  • Eldridge was one of the authors (with Gould) of punctuated equilibrium theory. This states that, if you look at the fossil record, what we see are species emerging, persisting with little change for a while, and then disappearing from the fossil record. They theorize that most species most of the time are at equilibrium with their environment, and so do not change much. But these periods of equilibrium are punctuated by disequilibrium – periods of change when species will have to migrate, evolve, or go extinct.
  • This does not mean that speciation does not take place. And if you look at the fossil record we see a pattern of descendant species emerging from ancestor species over time – in a nice evolutionary pattern. Morris gives a complete misrepresentation of Eldridge’s point – once again we see intellectual dishonesty in his methods of an astounding degree.
  • Regarding the atheism = religion comment, it reminds me of a great analogy that I first heard on twitter from Evil Eye. (paraphrase) “those that say atheism is a religion, is like saying ‘not collecting stamps’ is a hobby too.”
  • Morris next tackles the genetic evidence, writing: More often is the argument used that similar DNA structures in two different organisms proves common evolutionary ancestry. Neither argument is valid. There is no reason whatever why the Creator could not or would not use the same type of genetic code based on DNA for all His created life forms. This is evidence for intelligent design and creation, not evolution.
  • Here is an excellent summary of the multiple lines of molecular evidence for evolution. Basically, if we look at the sequence of DNA, the variations in trinucleotide codes for amino acids, and amino acids for proteins, and transposons within DNA we see a pattern that can only be explained by evolution (or a mischievous god who chose, for some reason, to make life look exactly as if it had evolved – a non-falsifiable notion).
  • The genetic code is essentially comprised of four letters (ACGT for DNA), and every triplet of three letters equates to a specific amino acid. There are 64 (4^3) possible three letter combinations, and 20 amino acids. A few combinations are used for housekeeping, like a code to indicate where a gene stops, but the rest code for amino acids. There are more combinations than amino acids, so most amino acids are coded for by multiple combinations. This means that a mutation that results in a one-letter change might alter from one code for a particular amino acid to another code for the same amino acid. This is called a silent mutation because it does not result in any change in the resulting protein.
  • It also means that there are very many possible codes for any individual protein. The question is – which codes out of the gazillions of possible codes do we find for each type of protein in different species. If each “kind” were created separately there would not need to be any relationship. Each kind could have it’s own variation, or they could all be identical if they were essentially copied (plus any mutations accruing since creation, which would be minimal). But if life evolved then we would expect that the exact sequence of DNA code would be similar in related species, but progressively different (through silent mutations) over evolutionary time.
  • This is precisely what we find – in every protein we have examined. This pattern is necessary if evolution were true. It cannot be explained by random chance (the probability is absurdly tiny – essentially zero). And it makes no sense from a creationist perspective. This same pattern (a branching hierarchy) emerges when we look at amino acid substitutions in proteins and other aspects of the genetic code.
  • Morris goes for the second law of thermodynamics again – in the exact way that I already addressed. He responds to scientists correctly pointing out that the Earth is an open system, by writing: This naive response to the entropy law is typical of evolutionary dissimulation. While it is true that local order can increase in an open system if certain conditions are met, the fact is that evolution does not meet those conditions. Simply saying that the earth is open to the energy from the sun says nothing about how that raw solar heat is converted into increased complexity in any system, open or closed. The fact is that the best known and most fundamental equation of thermodynamics says that the influx of heat into an open system will increase the entropy of that system, not decrease it. All known cases of decreased entropy (or increased organization) in open systems involve a guiding program of some sort and one or more energy conversion mechanisms.
  • Energy has to be transformed into a usable form in order to do the work necessary to decrease entropy. That’s right. That work is done by life. Plants take solar energy (again – I’m not sure what “raw solar heat” means) and convert it into food. That food fuels the processes of life, which include development and reproduction. Evolution emerges from those processes- therefore the conditions that Morris speaks of are met.
  • But Morris next makes a very confused argument: Evolution has neither of these. Mutations are not “organizing” mechanisms, but disorganizing (in accord with the second law). They are commonly harmful, sometimes neutral, but never beneficial (at least as far as observed mutations are concerned). Natural selection cannot generate order, but can only “sieve out” the disorganizing mutations presented to it, thereby conserving the existing order, but never generating new order.
  • The notion that evolution (as if it’s a thing) needs to use energy is hopelessly confused. Evolution is a process that emerges from the system of life – and life certainly can use solar energy to decrease its entropy, and by extension the entropy of the biosphere. Morris slips into what is often presented as an information argument.  (Yet again – already dealt with. The pattern here is that we are seeing a shuffling around of the same tired creationists arguments.) It is first not true that most mutations are harmful. Many are silent, and many of those that are not silent are not harmful. They may be neutral, they may be a mixed blessing, and their relative benefit vs harm is likely to be situational. They may be fatal. And they also may be simply beneficial.
  • Morris finishes with a long rambling argument that evolution is religion. Evolution is promoted by its practitioners as more than mere science. Evolution is promulgated as an ideology, a secular religion — a full-fledged alternative to Christianity, with meaning and morality . . . . Evolution is a religion. This was true of evolution in the beginning, and it is true of evolution still today. Morris ties evolution to atheism, which, he argues, makes it a religion. This assumes, of course, that atheism is a religion. That depends on how you define atheism and how you define religion – but it is mostly wrong. Atheism is a lack of belief in one particular supernatural claim – that does not qualify it as a religion.
  • But mutations are not “disorganizing” – that does not even make sense. It seems to be based on a purely creationist notion that species are in some privileged perfect state, and any mutation can only take them farther from that perfection. For those who actually understand biology, life is a kluge of compromises and variation. Mutations are mostly lateral moves from one chaotic state to another. They are not directional. But they do provide raw material, variation, for natural selection. Natural selection cannot generate variation, but it can select among that variation to provide differential survival. This is an old game played by creationists – mutations are not selective, and natural selection is not creative (does not increase variation). These are true but irrelevant, because mutations increase variation and information, and selection is a creative force that results in the differential survival of better adapted variation.
  •  
    One of my earlier posts on SkepticBlog was Ten Major Flaws in Evolution: A Refutation, published two years ago. Occasionally a creationist shows up to snipe at the post, like this one:i read this and found it funny. It supposedly gives a scientific refutation, but it is full of more bias than fox news, and a lot of emotion as well.here's a scientific case by an actual scientists, you know, one with a ph. D, and he uses statements by some of your favorite evolutionary scientists to insist evolution doesn't exist.i challenge you to write a refutation on this one.http://www.icr.org/home/resources/resources_tracts_scientificcaseagainstevolution/Challenge accepted.
Weiye Loh

Science-Based Medicine » Skepticism versus nihilism about cancer and science-... - 0 views

  • I’m a John Ioannidis convert, and I accept that there is a lot of medical literature that is erroneous. (Just search for Dr. Ioannidis’ last name on this blog, and you’ll find copious posts praising him and discussing his work.) In fact, as I’ve pointed out, most medical researchers instinctively know that most new scientific findings will not hold up to scrutiny, which is why we rarely accept the results of a single study, except in unusual circumstances, as being enough to change practice. I also have pointed out many times that this is not necessarily a bad thing. Replication is key to verification of scientific findings, and more often than not provocative scientific findings are not replicated. Does that mean they shouldn’t be published?
  • As for pseudoscience, I’m half tempted to agree with Dr. Spector, but just not in the way he thinks. Unfortunately, over the last 20 years or so, there has been an increasing amount of pseudoscience in the medical literature in the form of “complementary and alternative medicine” (CAM) studies of highly improbable remedies or even virtually impossible ones (i.e., homeopathy). However, that does not appear to be what Dr. Spector is talking about, which is why I looked up his references. The second reference is to an SI article from 2009 entitled Science and Pseudoscience in Adult Nutrition Research and Practice. There, and only there, did I find out just what it is that Dr. Spector apparently means by “pseudoscience”: By pseudoscience, I mean the use of inappropriate methods that frequently yield wrong or misleading answers for the type of question asked. In nutrition research, such methods also often misuse statistical evaluations.
  • Dr. Spector doesn’t really know the difference between inadequately rigorous science and pseudoscience! Now, don’t get me wrong. I know that it’s not always easy to distinguish science from pseudoscience, especially at the fringes, but in general bad science has to go a lot further than Dr. Spector thinks to merit the the term “pseudoscience.” It is clear (to me, at least) from his articles that Dr. Spector throws around the term “pseudoscience” around rather more loosely than he should, using it as a pejorative for any clinical science less rigorous than a randomized, double-blind, placebo-controlled trial that meets FDA standards for approval of a drug (his pharma background coming to the fore, no doubt). Pseudoscience, Dr. Spector. You keep using that word. I do not think it means what you think it means. Indeed, I almost get the impression from his articles that Dr. Spector views any study that doesn’t reach FDA-level standards for drug approval to be pseudoscience.
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  • Medical science, when it works well, tends to progress from basic science, to small pilot studies, to larger randomized studies, and then–only then–to those big, rigorous, insanely expensive randomized, double-blind, placebo-controlled trials. Dr. Spector mentions hierarchies of evidence, but he seems to fall into a false dichotomy, namely that if it’s not Level I evidence, it’s crap. The problem is, as Mark pointed out, in medicine we often don’t have Level I evidence for many questions. Indeed, for some questions, we will never have Level I evidence. Clinical medicine involves making decisions in the midst of uncertainty, sometimes extreme uncertainty.
  • Dr. Spector then proceeds to paint a picture of reckless physicians proceeding on crappy studies to pump women full of hormones. Actually, it was more than a bit more complicated on than that. That was the time when I was in my medical training, and I remember the discussions we had regarding the strength (or lack thereof) of the epidemiological data and the lack of good RCTs looking at HRT. I also remember that nothing works as well to relieve menopausal symptoms as HRT, an observation we have been reminded of again since 2003, which is the year when the first big study came out implicating HRT in increasing the risk of breast cancer (more later).
  • I found a rather fascinating editorial in the New England Journal of Medicine from more than 20 years ago that discussed the state of the evidence back then with regard to estrogen and breast cancer: Evidence that estrogen increases the risk of breast cancer has been surprisingly difficult to obtain. Clinical and epidemiologic studies and studies in animals strongly suggest that endogenous estrogen plays a part in causing breast cancer. If so, exogenous estrogen should be a potent promoter of breast cancer. Although more than 20 case–control and prospective studies of the relation of breast cancer and noncontraceptive estrogen use have failed to demonstrate the expected association, relatively few women in these studies used estrogen for extended periods. Studies of the use of diethylstilbestrol and oral contraceptives suggest that a long exposure or latency may be necessary to show any association between hormone use and breast cancer. In the Swedish study, only six years of follow-up was needed to demonstrate an increased risk of breast cancer with the postmenopausal use of estradiol. It should be noted, however, that half the women in the subgroup that provided detailed data on the duration of hormone use had taken estrogen for many years before their base-line prescription status was defined. The duration of estrogen exposure in these women before the diagnosis of breast cancer was probably seriously underestimated; a short latency cannot be attributed to estradiol on the basis of these data. Other recent studies of the use of noncontraceptive estrogen suggest a slightly increased risk of breast cancer after 15 to 20 years’ use.
  • even now, the evidence is conflicting regarding HRT and breast cancer, with the preponderance of evidence suggesting that mixed HRT (estrogen and progestin) significantly increases the risk of breast cancer, while estrogen-alone HRT very well might not increase the risk of breast cancer at all or (more likely) only very little. Indeed, I was just at a conference all day Saturday where data demonstrating this very point were discussed by one of the speakers. None of this stops Dr. Spector from categorically labeling estrogen as a “carcinogen that causes breast cancers that kill women.” Maybe. Maybe not. It’s actually not that clear. The problem, of course, is that, consistent with the first primary reports of WHI results, the preponderance of evidence finding health risks due to HRT have indicted the combined progestin/estrogen combinations as unsafe.
Weiye Loh

Don't dumb me down | Science | The Guardian - 0 views

  • Science stories usually fall into three families: wacky stories, scare stories and "breakthrough" stories.
  • these stories are invariably written by the science correspondents, and hotly followed, to universal jubilation, with comment pieces, by humanities graduates, on how bonkers and irrelevant scientists are.
  • A close relative of the wacky story is the paradoxical health story. Every Christmas and Easter, regular as clockwork, you can read that chocolate is good for you (www.badscience.net/?p=67), just like red wine is, and with the same monotonous regularity
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  • At the other end of the spectrum, scare stories are - of course - a stalwart of media science. Based on minimal evidence and expanded with poor understanding of its significance, they help perform the most crucial function for the media, which is selling you, the reader, to their advertisers. The MMR disaster was a fantasy entirely of the media's making (www.badscience.net/?p=23), which failed to go away. In fact the Daily Mail is still publishing hysterical anti-immunisation stories, including one calling the pneumococcus vaccine a "triple jab", presumably because they misunderstood that the meningitis, pneumonia, and septicaemia it protects against are all caused by the same pneumococcus bacteria (www.badscience.net/?p=118).
  • people periodically come up to me and say, isn't it funny how that Wakefield MMR paper turned out to be Bad Science after all? And I say: no. The paper always was and still remains a perfectly good small case series report, but it was systematically misrepresented as being more than that, by media that are incapable of interpreting and reporting scientific data.
  • Once journalists get their teeth into what they think is a scare story, trivial increases in risk are presented, often out of context, but always using one single way of expressing risk, the "relative risk increase", that makes the danger appear disproportionately large (www.badscience.net/?p=8).
  • he media obsession with "new breakthroughs": a more subtly destructive category of science story. It's quite understandable that newspapers should feel it's their job to write about new stuff. But in the aggregate, these stories sell the idea that science, and indeed the whole empirical world view, is only about tenuous, new, hotly-contested data
  • Articles about robustly-supported emerging themes and ideas would be more stimulating, of course, than most single experimental results, and these themes are, most people would agree, the real developments in science. But they emerge over months and several bits of evidence, not single rejiggable press releases. Often, a front page science story will emerge from a press release alone, and the formal academic paper may never appear, or appear much later, and then not even show what the press reports claimed it would (www.badscience.net/?p=159).
  • there was an interesting essay in the journal PLoS Medicine, about how most brand new research findings will turn out to be false (www.tinyurl.com/ceq33). It predictably generated a small flurry of ecstatic pieces from humanities graduates in the media, along the lines of science is made-up, self-aggrandising, hegemony-maintaining, transient fad nonsense; and this is the perfect example of the parody hypothesis that we'll see later. Scientists know how to read a paper. That's what they do for a living: read papers, pick them apart, pull out what's good and bad.
  • Scientists never said that tenuous small new findings were important headline news - journalists did.
  • there is no useful information in most science stories. A piece in the Independent on Sunday from January 11 2004 suggested that mail-order Viagra is a rip-off because it does not contain the "correct form" of the drug. I don't use the stuff, but there were 1,147 words in that piece. Just tell me: was it a different salt, a different preparation, a different isomer, a related molecule, a completely different drug? No idea. No room for that one bit of information.
  • Remember all those stories about the danger of mobile phones? I was on holiday at the time, and not looking things up obsessively on PubMed; but off in the sunshine I must have read 15 newspaper articles on the subject. Not one told me what the experiment flagging up the danger was. What was the exposure, the measured outcome, was it human or animal data? Figures? Anything? Nothing. I've never bothered to look it up for myself, and so I'm still as much in the dark as you.
  • Because papers think you won't understand the "science bit", all stories involving science must be dumbed down, leaving pieces without enough content to stimulate the only people who are actually going to read them - that is, the people who know a bit about science.
  • Compare this with the book review section, in any newspaper. The more obscure references to Russian novelists and French philosophers you can bang in, the better writer everyone thinks you are. Nobody dumbs down the finance pages.
  • Statistics are what causes the most fear for reporters, and so they are usually just edited out, with interesting consequences. Because science isn't about something being true or not true: that's a humanities graduate parody. It's about the error bar, statistical significance, it's about how reliable and valid the experiment was, it's about coming to a verdict, about a hypothesis, on the back of lots of bits of evidence.
  • science journalists somehow don't understand the difference between the evidence and the hypothesis. The Times's health editor Nigel Hawkes recently covered an experiment which showed that having younger siblings was associated with a lower incidence of multiple sclerosis. MS is caused by the immune system turning on the body. "This is more likely to happen if a child at a key stage of development is not exposed to infections from younger siblings, says the study." That's what Hawkes said. Wrong! That's the "Hygiene Hypothesis", that's not what the study showed: the study just found that having younger siblings seemed to be somewhat protective against MS: it didn't say, couldn't say, what the mechanism was, like whether it happened through greater exposure to infections. He confused evidence with hypothesis (www.badscience.net/?p=112), and he is a "science communicator".
  • how do the media work around their inability to deliver scientific evidence? They use authority figures, the very antithesis of what science is about, as if they were priests, or politicians, or parent figures. "Scientists today said ... scientists revealed ... scientists warned." And if they want balance, you'll get two scientists disagreeing, although with no explanation of why (an approach at its most dangerous with the myth that scientists were "divided" over the safety of MMR). One scientist will "reveal" something, and then another will "challenge" it
  • The danger of authority figure coverage, in the absence of real evidence, is that it leaves the field wide open for questionable authority figures to waltz in. Gillian McKeith, Andrew Wakefield, Kevin Warwick and the rest can all get a whole lot further, in an environment where their authority is taken as read, because their reasoning and evidence is rarely publicly examined.
  • it also reinforces the humanities graduate journalists' parody of science, for which we now have all the ingredients: science is about groundless, incomprehensible, didactic truth statements from scientists, who themselves are socially powerful, arbitrary, unelected authority figures. They are detached from reality: they do work that is either wacky, or dangerous, but either way, everything in science is tenuous, contradictory and, most ridiculously, "hard to understand".
  • This misrepresentation of science is a direct descendant of the reaction, in the Romantic movement, against the birth of science and empiricism more than 200 years ago; it's exactly the same paranoid fantasy as Mary Shelley's Frankenstein, only not as well written. We say descendant, but of course, the humanities haven't really moved forward at all, except to invent cultural relativism, which exists largely as a pooh-pooh reaction against science. And humanities graduates in the media, who suspect themselves to be intellectuals, desperately need to reinforce the idea that science is nonsense: because they've denied themselves access to the most significant developments in the history of western thought for 200 years, and secretly, deep down, they're angry with themselves over that.
  • had a good spirited row with an eminent science journalist, who kept telling me that scientists needed to face up to the fact that they had to get better at communicating to a lay audience. She is a humanities graduate. "Since you describe yourself as a science communicator," I would invariably say, to the sound of derisory laughter: "isn't that your job?" But no, for there is a popular and grand idea about, that scientific ignorance is a useful tool: if even they can understand it, they think to themselves, the reader will. What kind of a communicator does that make you?
  • Science is done by scientists, who write it up. Then a press release is written by a non-scientist, who runs it by their non-scientist boss, who then sends it to journalists without a science education who try to convey difficult new ideas to an audience of either lay people, or more likely - since they'll be the ones interested in reading the stuff - people who know their way around a t-test a lot better than any of these intermediaries. Finally, it's edited by a whole team of people who don't understand it. You can be sure that at least one person in any given "science communication" chain is just juggling words about on a page, without having the first clue what they mean, pretending they've got a proper job, their pens all lined up neatly on the desk.
Weiye Loh

Biomimicry: How Scientists Emulate Nature to Create Sustainable Designs | The Utopianis... - 0 views

  • “The core idea is that nature, imaginative by necessity, has already solved many of the problems we are grappling with. Animals, plants, and microbes are the consummate engineers. They have found what works, what is appropriate, and most important, what lasts here on Earth. This is the real news of biomimicry: After 3.8 billion years of research and development, failures are fossils, and what surrounds us is the secret to survival. Like the viceroy butterfly imitating the monarch, we humans are imitating the best adapted organisms in our habitat. We are learning, for instance, how to harness energy like a leaf, grow food like a prairie, build ceramics like an abalone, self-medicate like a chimp, create color like a peacock, compute like a cell, and run a business like a hickory forest.”
  • A more recent example of biomimetics in action is a biological laser created by two physicists at Harvard Medical School. Malte Gather and Seok Hyun Yun placed a single cell, genetically engineered to produce green fluorescent proteins originally found in jellyfish, into a cavity with two parallel mirrors on either side. When they exposed the cell to pulses of light, it emitted green fluorescent light that focused into a laser beam with the aid of the parallel mirrors. As Gather and Yun pointed out in their paper, the single-cell biological laser avoids the use of “artificial or engineered optical gain materials, such as doped crystals, semiconductors, synthetic dyes and purified gases.”
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    if one of our goals as a species is longevity, we may want to humble ourselves and take a look at how other species manage to live symbiotically with the earth instead of just on it. Biomimetics, or biomimicry, does just that.
Weiye Loh

God is not the Creator, claims academic - Telegraph - 1 views

  • Professor Ellen van Wolde, a respected Old Testament scholar and author, claims the first sentence of Genesis "in the beginning God created the Heaven and the Earth" is not a true translation of the Hebrew.
  • She said she eventually concluded the Hebrew verb "bara", which is used in the first sentence of the book of Genesis, does not mean "to create" but to "spatially separate". The first sentence should now read "in the beginning God separated the Heaven and the Earth"
  • She said: "It meant to say that God did create humans and animals, but not the Earth itself."
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  • She said she hoped that her conclusions would spark "a robust debate", since her finds are not only new, but would also touch the hearts of many religious people. She said: "Maybe I am even hurting myself. I consider myself to be religious and the Creator used to be very special, as a notion of trust. I want to keep that trust." A spokesman for the Radboud University said: "The new interpretation is a complete shake up of the story of the Creation as we know it." Prof Van Wolde added: "The traditional view of God the Creator is untenable now."
Weiye Loh

TODAYonline | World | Off-the-shelf body parts? - 0 views

  • LONDON - Scientific advances including techniques allowing patients to grow new joints inside their own bodies will allow the elderly to remain active well beyond their 100th birthdays, researchers claim. British scientists are working on a system which should allow the elderly to buy body parts "off the shelf" and even regenerate their own damaged joints and hearts. Their ultimate aim is to fix up the body with customised replacement parts grown to order. They have already carried out human trials on heart valves which are still working four years after they were transplanted. At the University of Leeds, Britain's biggest bioengineering unit and the world leader in artificial joint replacement research is coordinating a project that aims to give people 50 active years after the age of 50."It is the rise of the bionic pensioner," said Professor Christina Doyle, whose company is working with the university to develop the new technologies. "The idea is when something wears out, your surgeon can buy a replacement off the shelf or, more accurately, in a bag."The university is spending £50 million ($114 million) over the next five years on the new project. The main thrust of the research centres on a method of tissue and medical engineering which the university is at the forefront of developing. Led by the immunologist Professor Eileen Ingham, they are pioneering a technique of stripping the living cells from donor human and animal parts, leaving just the collagen or elastin "scaffold" of the tissue. These "biological shells", which could be for knee, ankle or hip ligaments, as well as blood vessels and heart valves, are then transplanted into the patient whose own body then invades them replacing the removed cells with their own. The technique, which could be available within five years, effectively removes the need for anti-rejection drugs. It is similar to the recently developed system of using stem cells to regrow organs outside the body, but costs about a tenth of the price.
Weiye Loh

Designers Make Data Much Easier to Digest - NYTimes.com - 0 views

  • On the benefit side, people become more engaged when they can filter information that is presented visually and make discoveries on their own. On the risk side, Professor Shneiderman says, tools as powerful as visualizations have the potential to mislead or confuse consumers. And privacy implications arise, he says, as increasing amounts of personal, housing, medical and financial data become widely accessible, searchable and viewable.
  • In the 1990s, Professor Shneiderman developed tree mapping, which uses interlocking rectangles to represent complicated data sets. The rectangles are sized and colored to convey different kinds of information, like revenue or geographic region, says Jim Bartoo, the chief executive of the Hive Group, a software company that uses tree mapping to help companies and government agencies monitor operational data. When executives or plant managers see the nested rectangles grouped together, he adds, they should be able to immediately spot anomalies or trends. In one tree-map visualization of a sales department on the Hive Group site, red tiles represent underperforming sales representatives while green tiles represent people who exceeded their sales quotas. So it’s easy to identify the best sales rep in the company: the biggest green tile. But viewers can also reorganize the display — by region, say, or by sales manager — to see whether patterns exist that explain why some employees are falling behind. “It’s the ability of the human brain to pick out size and color” that makes tree mapping so intuitive, Mr. Bartoo says. Information visualization, he adds, “suddenly starts answering questions that you didn’t know you had.”
  • data visualization is no longer just a useful tool for researchers and corporations. It’s also an entertainment and marketing vehicle.
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  • In 2009, for example, Stamen Design, a technology and design studio in San Francisco, created a live visualization of Twitter traffic during the MTV Video Music awards. In the animated graphic, floating bubbles, each displaying a photograph of a celebrity, expanded or contracted depending on the volume of Twitter activity about each star. The project provided a visceral way for viewers to understand which celebrities dominated Twitter talk in real time, says Eric Rodenbeck, the founder and creative director of Stamen Design.
  • Designers once created visual representations of data that would steer viewers to information that seemed the most important or newsworthy, he says; now they create visualizations that contain attractive overview images and then let users direct their own interactive experience — wherever it may take them. “It’s not about leading with a certain view anymore,” he says. “It’s about delivering the view that gets the most participation and engagement.”
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