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The origin of Aids denialism lies with one man. Peter Duesberg has spent the whole of his academic career at the University of California, Berkeley. In the 1970s he performed groundbreaking work that helped show how mutated genes cause cancer, an insight that earned him a well-deserved international reputation.

in the early 1980s, something changed. Duesberg attempted to refute his own theories, claiming that it was not mutated genes but rather environmental toxins that are cancer's true cause. He dismissed the studies of other researchers who had furthered his original work. Then, in 1987, he published a paper that extended his new train of thought to Aids.

Initially many scientists were open to Duesberg's ideas. But as evidence linking HIV to Aids mounted - crucially the observation that ARVs brought Aids sufferers who were on the brink of death back to life - the vast majority concluded that the debate was over. Nonetheless, Duesberg persisted with his arguments, and in doing so attracted a cabal of supporters

So if syphilis causes AIDS, and not HIV, where is the evidence? As microbiologist and epidemiolist Tara Smith points out in her excellent blog, Margulis offers none. Instead, she says to the credulous and uncritical interviewer: The idea that penicillin kills the cause of the disease is nuts. If you treat the painless chancre in the first few days of infection, you may stop the bacterium before the symbiosis develops, but if you really get syphilis, all you can do is live with the spirochete. The spirochete lives permanently as a symbiont in the patient. The infection cannot be killed because it becomes part of the patient’s genome and protein synthesis biochemistry. After syphilis establishes this symbiotic relationship with a person, it becomes dependent on human cells and is undetectable by any testing. Great. Just what we need: an untestable hypothesis promoted by assertion and reputation, not something concrete that scientists could test (although most specialists in microbiology would say the evidence is clear that the HIV retrovirus, and not the spirochaete bacterium Treponema pallidum, is the true cause of AIDS).

Has she never actually LOOKED at the hundreds of peer-reviewed scientific papers documenting the structure of the HIV virus, and the clear documentation of that virus in patients that suffer and die from AIDS? Or the fact that patients treated with anti-retrovirals manage to suppress their AIDS symptoms? Or the disaster in South Africa, when the government became active AIDS deniers, spread misinformation and myths about AIDS, and the infection rate shot up? Not even the hard-core AIDS deniers like Peter Duesberg deny that the HIV virus exists!

she slips outside the realm of science entirely, and becomes a full-fledged AIDS denier. My jaw just dropped when I read the following: There is a vast body of literature on syphilis spanning from the 1500s until after World War II, when the disease was supposedly cured by penicillin. It’s in our paper “Resurgence of the Great Imitator.” Our claim is that there’s no evidence that HIV is an infectious virus, or even an entity at all. There’s no scientific paper that proves that the HIV virus causes AIDS. Kary Mullis said in an interview that he went looking for a reference substantiating that HIV causes AIDS and discovered, “There is no such document.”