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Research Highlights KCNJ16-Depleted Kidney Organoids Recapitulate Tubulopathy and Lipid Recovery upon Statins Treatment Statin Treatment Reverses Lipid Accumulation in KCNJ16-Deficient Kidney Organoids T2+ T-regulatory Cells in Renal Inflammation and Fibrosis following Ischemic Kidney Injury Kidney Organoids Illuminate the Protective Role of ST2+ Tregs in Renal Inflammation and Fibrosis A perfusable, vascularized kidney organoid-on-chip model [Biofabrication] Microfluidic Kidney Organoid with Vascular Integration for Perfusion Studies. A Genetically Inducible Endothelial Niche Enables Vascularization of Human Kidney Organoids with Multilineage Maturation and Emergence of Renin Expressing Cells [Lab on a Chip] Brain Organoid sEVs Modulate Breast Cancer Invasion in Microphysiological Assays. Kidney Organoid Modeling of WT1 Mutations Reveals Key Regulatory Paths Underlying Podocyte Development [Advanced Science] WT1 Mutations in Kidney Organoids: Unveiling Regulatory Pathways.

Research Highlights Artificial Meshed Vessel-Induced Dimensional Breaking Growth of Human Brain Organoids and Multiregional Assembloids Modeling Neurodevelopmental Disorders with Vascularized Brain Organoids Modeling Lewy Body Disease with SNCA Triplication iPSC-Derived Cortical Organoids and Identifying Therapeutic Drugs Cortical Organoids Reveal Pathogenic Mechanisms in α-Synucleinopathies.

Brain Organoids, Neural Organoids | ISoOR ISoOR is at the forefront of research on brain and neural organoids, providing the latest information and insights in this rapidly evolving field. ISoOR regularly updates its platform with new findings and insights, ensuring access to the most current information. ISoOR also hosts conferences focused on neural and brain organoid with eyes, promoting networking and collaboration. Furthermore, ISoOR's Research Highlights provide concise summaries of impactful studies, keeping the scientific community informed and engaged.

Pancreatic Organoids Research Highlights Pancreatic Cancer Tumor Organoids Exhibit Subtype-Specific Differences in Metabolic Profiles Organoid Models Uncover Subtype-Specific Therapeutic Avenues in PDAC Patient-derived Organoid Pharmacotyping as A Predictive Tool for Therapeutic Selection in Pancreatic Ductal Adenocarcinoma Advancing Pancreatic Cancer Therapies with Patient-Derived Organoid Pharmacotyping Wnt-Deficient and Hypoxic Environment Orchestrates Squamous Reprogramming of Human Pancreatic Ductal Adenocarcinoma Integrating Organoid Systems to Elucidate the Epigenetic Mechanisms of Pancreatic Tumorigenesis

Journal of Organoid & Bioscience ISSN:3029-2271 The Journal of Organoid & Bioscience, the official stem cell research journal of the International Society of Organoid Research, is a distinguished open access, peer-reviewed international journal. The organoid journal specializes in publishing groundbreaking research in the field of organoids, encompassing basic, translational, and related studies. With its commitment to high-quality research, the Organoid Journal plays a crucial role in advancing the organoid field, serving as a vital resource for researchers, clinicians, and academics worldwide. If you want to know more about organoid journal impact factor, please visit our website.

Welcome to ISoOR 2023 From August 7 to 8, 2023, the International Society of Organoid Research (ISoOR) held its inaugural annual meeting in Singapore. Hosted by ISoOR and co-organized by the Pharmacological Society (Singapore) and Scipolis, the conference was themed "Organoid: Accelerate Your Research." It delved into subjects such as "Organoids and Precision Medicine," "Organoids and Regenerative Medicine," "Organoids and New Drug Development," as well as "The Organoid Market from an Investor's Perspective."

Research Highlights Optimization of Culture Conditions to Generate Vascularized Multi-Lineage Liver Organoids with Structural Complexity and Functionalityv Vascularized Multi-Lineage Liver Organoids: A New Frontier in Disease Modeling Evaluating the Effects of Perinatal Exposures to BPSIP on Hepatic Cholesterol Metabolism in Female and Male Offspring ICR Mice Breaking Barriers: Utilizing Liver Organoids to Study BPSIP's Metabolic Impact HKDC1 Promotes Liver Cancer Stemness Under Hypoxia via Stabilizing β-Catenin Exploiting Hepatic Organoid Models to Uncover HKDC1's Role in Liver Cancer Metastasis m6A-Dependent ITIH1 Regulated by TGF-β Acts as a Target for Hepatocellular Carcinoma Progression Recombinant ITIH1 Protein Inhibits Hepatocellular Carcinoma Growth in 3D Organoid Cultures

Pioneering Organoid Research at the"Organoids Are Us"Conference in Thailand: A Collaborative Endeavor to Drive Scientific Innovation Pioneering Organoid Research at the"Organoids Are Us"Conference in Thailand: A Collaborative Endeavor to Drive Scientific Innovation The "Organoids Are Us" symposium, held in the picturesque setting of Pattaya, Thailand, has successfully concluded, marking a significant milestone in the field of organoid research. The International Society of Organoid Research (ISoOR) was honored to be invited and to present at the conference.

Research Highlights Malignant Pleural Effusion Facilitates the Establishment and Maintenance of Tumor Organoid Biobank with Multiple Patient-Derived Lung Tumor Cell Sources Malignant Pleural Effusion Boosts Lung Cancer Organoid Establishment Modeling Lung Adenocarcinoma Metastases Using Patient-Derived Lung Organoids The Role of Organoid Models in Evaluating GOQD-PEI/S2.2/pLVSIN-iC9 Gene Therapy

Research Highlights AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming [Cell Proliferation]In Organoid Models, AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming. Ear Organoids Feb 24, 2024 Varying Mechanical Forces Drive Sensory Epithelium Formation [Science Advances] Organoid models reveals the impact of mechanical stress on the formation of inner ear sensory epithelium and its signaling regulatory molecular mechanisms, providing new insights fo.

Research Highlights Characterizing the Effects of Triclosan and Triclocarban on the Intestinal Epithelial Homeostasis Using Small Intestinal Organoids Assessment of TCS/TCC Toxicity on Intestinal Epithelium Using Organoid Models.

Efficient and Reproducible Generation of Human iPSC-Derived Cardiomyocytes and Cardiac Organoids in Stirred Suspension Systems [Nature Communications] Suspension Culture for High-Yield iPSC Cardiac Cells and Organoids.