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Ropinirole, bromocriptine, and piribedil are associated with the highest incidence rates of adverse effects in Parkinson's disease, according to a review published online Sept. 4 in CNS Neuroscience & Therapeutics. Bao-Dong Li, from the Hebei Province Cangzhou Hospital of Integrated Traditional and Western Medicine in China, and colleagues conducted a systematic review to compare the adverse effects of 11 drugs used to treat Parkinson's disease. Data were included from 24 randomized controlled trials. The researchers found that, compared with placebo, the incidence of adverse reactions of ropinirole, rotigotine, entacapone, and sumanirole were higher in terms of nausea. The incidence rates of dyskinesia side effects were highest with ropinirole, while in terms of patients' hallucination, pramipexole was significantly higher. The surface under the cumulative ranking curve values of all drugs showed that the incidence of adverse reaction of pergolide was relatively high (nausea, 83.5 percent; hallucination, 79.8 percent); the incidence of dyskinesia and somnolence was higher with ropinirole (80.5 and 69.4 percent); in terms of dizziness, the incidence of adverse reaction of piribedil was higher (67.0 percent), and in terms of constipation, the incidence of bromocriptine was relatively high (62.3 percent). "In addition to current forms of treatment, we hope that our results can produce useful information for further development of new drugs to treat Parkinson's disease based on the natures of each drug," the authors write.

Most physicians on Twitter with a financial conflict of interest (FCOI) and frequent tweets mention specific drugs for which they have a conflict, according to a study published in the September issue of The Lancet Haematology. Victoria Kaestner, from the Oregon Health & Science University in Portland, and colleagues examined whether conflicted physicians tweet about specific products for which they have a FCOI. A total of 156 physicians who tweeted a median of 584 times were included, with a 2014 median general payment totaling $13,600.

American Educational Institute (AEI) Medical-Dental-Legal Update is organized by American Educational Institute (AEI) and will be held during Oct 02, 2017 - Apr 27, 2018 at Grand Wailea Resort, Maui, Hawaii, United States of America. The target audience for this medical event is Dentists. This CME Conference has been approved for a maximum of 20 AMA PRA Category 1 Credits. Conference Description : You practice in a dynamic and challenging environment. While keeping clinically current is imperative, it isn't enough. You must also acquire the skills necessary to navigate a professional liability minefield, manage a more effective and efficient practice, and navigate a maze of healthcare laws and regulations. The 2017-18 Medical-Dental-Legal Update Update is designed to assist you in that endeavor. The course, offered weekly in 32 enviable destinations, is a unique, 20-hour survey of the intersection of medicine and law as well as selected clinical topics. Produced in state-of-the-art production studios with broadcast-grade, HD digital technology. This Conference offers vital instruction from national experts in the fields of law, medicine, dentistry, asset protection, revenue cycle management and practice management. And their presentations include discussions ranging from domestic violence, payment receipt optimization, medical malpractice, fraud and abuse, and optimizing retirement and benefit plan structures, to the oral-systemic connection, medical errors, Hepatitis B & C, neurology and cardiovascular fitness. The Update is presented in a structured classroom setting affording you the opportunity for dialogue with your medical, dental and legal colleagues, and through September 28, 2018, you will have over 900 opportu­nities to attend at your choice of 30 premier sun and ski resorts - virtually any week you choose. Conference Objectives are: * Recommend preventive lifestyle behaviors and protective pharmacothe­rapy. * Assess the appropriate­ness of th

American Educational Institute (AEI) Medical-Dental-Legal Update is organized by American Educational Institute (AEI) and will be held during Oct 02, 2017 - Sep 28, 2018 at Dickenson Square, Maui, Hawaii, United States of America. The target audience for this medical event is Dentists. This CME Conference has been approved for a maximum of 20 AMA PRA Category 1 Credits. Conference Description : You practice in a dynamic and challenging environment. While keeping clinically current is imperative, it isn't enough. You must also acquire the skills necessary to navigate a professional liability minefield, manage a more effective and efficient practice, and navigate a maze of healthcare laws and regulations. The 2017-18 Medical-Dental-Legal Update Update is designed to assist you in that endeavor. The course, offered weekly in 32 enviable destinations, is a unique, 20-hour survey of the intersection of medicine and law as well as selected clinical topics. Produced in state-of-the-art production studios with broadcast-grade, HD digital technology. This Conference offers vital instruction from national experts in the fields of law, medicine, dentistry, asset protection, revenue cycle management and practice management. And their presentations include discussions ranging from domestic violence, payment receipt optimization, medical malpractice, fraud and abuse, and optimizing retirement and benefit plan structures, to the oral-systemic connection, medical errors, Hepatitis B & C, neurology and cardiovascular fitness. Conference Objectives are: * Recommend preventive lifestyle behaviors and protective pharmacothe­rapy. * Assess the appropriate­ness of the direct patient care model for your practice * Utilize a variety of clinically relevant but relatively unknown treatments. * Better recognize and respond to victims of child violence. * Better understand and deal with medical malpractice litigation. * More effectively reduce practice risk and protect assets exposed t

Management of type 2 diabetes should include shared decision making, and patients should be offered individualized diabetes self-management education and glycemic management plans, according to a summary of a clinical practice guideline published online Oct. 23 in the Annals of Internal Medicine. Paul R. Conlin, M.D., from the VA Boston Healthcare System in West Roxbury, Massachusetts, and colleagues convened a joint U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) Evidence-Based Practice Work Group to develop a guideline for management of type 2 diabetes mellitus. The authors provided updates on management within seven areas: patient-centered care and shared decision making, glycemic biomarkers, target ranges of hemoglobin A1c (HbA1c), individualized treatment plans, pharmacologic treatment in the outpatient setting, glucose targets for critically ill patients, and treatment for patients in the hospital. Patients should be offered individualized diabetes self-management education, as well as individualized glycemic management plans and target ranges for HbA1c. "In summary, the VA/DoD CPG [clinical practice guideline] attempts to convey to clinicians, policymakers, and patients the rationale for personalizing treatment on the basis of results from major trials, limitations of the HbA1c test, and evaluation of patient risk for adverse drug events. Conveying complex information in an understandable manner to individual patients and families through a formal process of shared decision making is thus foundational to setting and revising goals that are meaningful, safe, and achievable in everyday clinical practice," the authors write.

Most ophthalmologists write no more than 10 opioid prescriptions annually, with a mean supply per prescription of five days, according to a study published online Oct. 5 in JAMA Ophthalmology. Shriji Patel, M.D., and Paul Sternberg Jr., M.D., both from Vanderbilt Eye Institute in Nashville, Tennessee, analyzed physician and beneficiary measures using Medicare Part D Prescriber Data (2013 to 2015) to determine prescribing patterns for opioid drugs for participating ophthalmologists. The researchers found that, consistently, 88 to 89 percent of ophthalmologists wrote 10 opioid prescriptions or fewer annually. Only about 1 percent of ophthalmologists wrote more than 100 opioid prescriptions annually. On average, ophthalmologists wrote seven opioid prescriptions per year with a mean supply of five days. The six states with the highest volume of annual opioid prescriptions per ophthalmologist were in the South.

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