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Sastry endorses David Kolb’s “learning loop” model: concrete experience, observation and reflection, forming abstract concepts, then further implementing and analyzing. She ponders if this cycle can transcend classroom learning to engender change in the world. Her own research and consulting in health care delivery are based on such a stepped method. She stresses that an integrated, holistic perspective is also required. For instance, a malnourished patient will be unable to absorb drugs administered for AIDS; medicine is insufficient without food. As to the larger picture, she says “obviously we’ve got to tackle global warming and carbon emissions, but we also need to tackle poverty.”

Over 200 scientific and medical journals are taking part. For our theme issue, we asked a wide variety of commentators worldwide—including clinicians, medical researchers, health reporters, policy makers, health activists, and development experts—to name the single intervention that they think would improve the health of those living in poverty.