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This article discusses new Duke University research showing a highly significant correlation (p = 0.007) between higher vitamin D intake and MRI brain lesions (http://www.fasebj.org/cgi/content/meeting_abstract/21/6/A1072), as well as the potential for lesion reversal. These lesions have been associated with cognitive impairment, stroke, psychiatric disorders and mortality. This article also discusses the levels of vitamin D and calcium needed to avoid osteoporosis and vascular calcification in the light of new research on blockage of the vitamin D receptor due to bacterial products and elevated 25D.

Discussion of both preventive and therapeutic doses / protocols for Vitamin D3 for influenza. Discussion of actual / potential harm in flu shots.

I've contributed a lot to this discussion.  Perhaps I've been obssessive.  I'm concerned about the state of healthcare in this country, though.  I'm upset about the rampant myths and lies being tossed around about healthcare reform.  I'm concerned about all the lazy thinking we citizens are exhibiting. Misinformation, misunderstandings, bias, prejudice, narrowly self-interested polemics, anger, manipulations, and nastiness are badly hurting the process (and probable outcome) of healthcare reform debates and efforts. I can't NOT write long, detailed comments when I read stuff that's...well...WHACK!

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Natural Standard Herbal Pharmacotherapy: An Evidence-Based Approach is now available for purchase. The book provides practical guidance on the use of herbal therapies for medical conditions. This reference tool will be an essential part of herbal pharmacy core curricula for all healthcare disciplines. Chapters are organized by medical condition and present supportive evidence, including potential mechanisms of action and dosing, for selected herbal therapies. The chapters also include integrative therapy plans to help clinicians quickly assess patient needs and create cohesive treatment plans. In addition, adjunct therapies, including herbs, supplements and modalities, that are commonly used in combination with primary treatments are discussed. Case studies, which summarize efficacy, safety, dosing and interactions for high-utilization products, help prepare healthcare providers for patient counseling in clinical practice. Review questions, similar to those on national board exams, allow readers to evaluate their learning and identify areas for further study. The book also includes several appendices, which provide information about lab values as well as the safety, interactions and pharmacokinetics of select herbs.

Vitamin D, nervous system and aging.\nP. Tuohimaa, T. Keisala, A. Minasyan, J. Cachat and A. Kalueff. .\nPsychoneuroendocrinology, Volume 34, Supplement 1, December 2009, Pages S278-S286\n NEUROACTIVE STEROIDS: EFFECTS and MECHANISMS ofACTION\n \n\nReview of vitamin D3, its active metabolites, and their functioning in the central nervous system (CNS), especially in relation to nervous system pathologies and aging. The vitamin D3 endocrine system consists of 3 active calcipherol hormones: calcidiol (25OHD3), 1α-calcitriol (1α,25(OH)2D3) and 24-calcitriol (24,25(OH)2D3). The impact of the calcipherol hormone system on aging, health and disease is discussed. Low serum calcidiol concentrations are associated with an increased risk of several chronic diseases including osteoporosis, cancer, diabetes, autoimmune disorders, hypertension, atherosclerosis, and muscle weakness ~ all of which can be considered aging-related diseases. The relationship of many of these diseases and aging-related changes in physiology show a U-shaped response curve to serum calcidiol concentrations. Clinical data suggest that vitamin D3 insufficiency is associated with an increased risk of several CNS diseases, including multiple sclerosis, Alzheimers, Parkinsons, seasonal affective disorder (SAD), and schizophrenia. In line with this, recent animal and human studies suggest that vitamin D insufficiency is associated with abnormal development and functioning of the CNS. * Overall, imbalances in the calcipherol system appear to cause abnormal function, including premature aging, of the CNS. *

Rader also believes that the MEGA trial raises important questions about just how widespread the use of statin therapy should be in primary prevention...reignite discussion on over-the-counter low-dose statins.

We describe how innate and adaptive immune cascades trigger the release of cytokines and chemokines, resulting in the initiation and progression of atherosclerosis. We discuss how cytokines have direct and indirect effects on myocardial function.

Obama's Impact on Healthcare and Pharma Industry Here's where pharma industry people can discuss the pros and cons of Obama's plans for healthcare in the US and the pharma industry.

Discussion of barriers presented by health insurance procedures, protocols, and economics to direct and efficient delivery of medical care.