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Clinical courses of primary immune-mediated hemolytic anemia (pIMHA) in dogs are highly variable, however, limited information is available to predict their accurate prognoses. To evaluate the prognostic significance of clinical factors and to propose a scoring system to predict prognoses, the medical records of seventy-one dogs with pIMHA were reviewed.

The effective immortalization of various primary cells presented in animal body is implemented by using different genes and agents. Cellular immortalization can be carried out in lots of ways;and custom service is available in the market to help generate immortalized cell lines.

Source Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA. Abstract OBJECTIVE: To identify factors associated with onset and continued elicitation of tail chasing in Bull Terriers and other terriers and to determine response to treatment with clomipramine hydrochloride, a serotonin-reuptake inhibitor. DESIGN: Prospective study.

Eleven dogs diagnosed with refractory idiopathic epilepsy were treated orally with gabapentin for a minimum of three months at an initial dose of 10 mg/kg every eight hours. They were all experiencing episodes of generalised tonic-clonic seizures and had been treated chronically with a combination of phenobarbital and potassium bromide at doses sufficient to reach acceptable therapeutic serum levels without causing significant side effects. In each dog, the number of seizures per week, the average duration of the seizures and the number of days on which seizures occurred were compared for the three months before and after they were treated with gabapentin. A minimum 50 per cent reduction in the number of seizures per week was interpreted as a positive response to gabapentin, and six of the dogs showed a positive response. After the addition of gabapentin, both the number of seizures per week (P= 0·005) and the number of days with any seizures in a one-week period (P=0·03) were significantly reduced. Mild side effects of ataxia and sedation were observed in five of the dogs, but they were not severe enough to warrant the treatment being discontinued during the trial.

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This is an study designed to probe the efficency and secondary effects in using recombinant human erythropoietin to treat anemia ( that contributes to clinical manifestations of chronic renal failure in cats ( and dogs)

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Abstract Oral glucosamine was compared to a placebo for the management of cats with feline idiopathic cystitis (FIC) in a randomised, double-blinded, placebo-controlled, study. Forty cats with a history of recurrent cystitis due to FIC were divided into two groups and treated daily per os with either 125 mg N-acetyl glucosamine or a placebo for six months.

In caring for sick animals, all veterinarians eventually find themselves faced with a patient that has anemia of such severity as to require a blood transfusion. Access to blood products has improved in the past few years. Veterinary blood banks can supply canine, feline, and even ferret blood within 24 hours via overnight mail.

Knowledge of the cat has advanced rapidly in the 9 years since the second edition of Feline Medicine and Therapeutics was published. The primary object of this book remains the same however - to help veterinary surgeons and students to practise the art and science of feline medicine.

Similarly to the dog, most cases of hyperadrenocorticism in the cat are caused by the excessive secretion of adrenocorticotropic hormone (ACTH) from the pars intermedia or pars distalis of the pituitary gland which stimulates the adrenal glands to secrete an excessive amount of cortisol.

This article will review the laboratory tests that are available for diagnosis of HC. An emphasis will be made on the clinical process that leads to the decision to perform those tests and common misconceptions and issues that arise when performing them.

The serum transaminase activity appears to be proportional to the extent of muscle damage. This increase may permit the objective diagnosis of white muscle disease without sacrifice of the animal.

Abstract Feline elimination problems are the leading behavioral complaint of cat owners. When presented with a feline elimination problem there are three main diagnostic categories: medical problems, marking or toileting problems. It isimportant to first perform diagnostic tests to rule out and/or address underlying medical issues and all feline housesoiling patients should receive a comprehensive physical examination.

This article provides data to suggest that feeding a diet specifically formulated to meet the needs of cats with CRF, together with phosphate binding drugs if required, controls hyperphosphataemia and secondary renal hyperparathyroidism, is associated with an increased survival time.

estudio sobre la utilidad de un spray (Zero Odor) como tratamiento para mejorar el atratactivo de la bandeja en casos de gatos con eliminación inadecuada por aversión a la misma

Abstract Decreasing litter box odor may be an important treatment component in addressing feline inappropriate elimination. A three-phase study was conducted to determine if the use of Zero Odor litter box spray increases the preference of litter boxes to cats, presumably by its odor-eliminating quality.

Tracheal Collapse in Dogs Tracheal collapse is a common cause of airway obstruction in dogs. The trachea, or "windpipe," is a tube made up of sturdy rings of cartilage through which air is transported to and from the lungs. Sometimes, however, the tracheal rings begin to collapse, and as air is squeezed through, a characteristic honking cough results.

Surgical Neurology Branch (R.J.W., A.O.V., H.L.D., J.W., E.H.O.), National Institutes of Neurological Disorders and Stroke, National Institutes of Health, and Reproductive Medicine and Biology Branch (L.K.N.), National Institute of Child Health and Development, National Institutes of Health, Bethesda, Maryland 20892-1414 Address all correspondence and requests for reprints to: Edward H.